neurokinin b has been researched along with kiss1 protein, human in 225 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (2.67) | 29.6817 |
| 2010's | 152 (67.56) | 24.3611 |
| 2020's | 67 (29.78) | 2.80 |
| Authors | Studies |
|---|---|
| Caraty, A; Ciofi, P; Clarke, IJ; Coolen, LM; de Oliveira, CV; Goodman, RL; Iqbal, J; Jafarzadehshirazi, MR; Lehman, MN; Pereira, A; Smith, JT | 1 |
| Rance, NE | 1 |
| Akalin, NS; Cook, JR; Guclu, M; Imamoglu, S; Kotan, LD; Mungan, NO; O'Rahilly, S; Porter, KM; Reimann, F; Semple, RK; Serin, A; Topaloglu, AK; Yalin, AS; Yuksel, B | 1 |
| Latronico, AC | 1 |
| Semple, RK; Topaloglu, AK | 1 |
| Clifton, DK; Kauffman, AS; Kim, J; Navarro, VM; Steiner, RA | 1 |
| Chavkin, C; Clifton, DK; Gottsch, ML; Navarro, VM; Okamura, H; Steiner, RA | 1 |
| Cheng, G; Coolen, LM; Goodman, RL; Lehman, MN; Padmanabhan, V | 1 |
| Challis, BG; Coll, AP; Corander, MP; Dhillo, WS; Huhtaniemi, IT; Jovanovic, Z; Loraine Tung, YC; Murphy, KG; O'Rahilly, S; Rimmington, D; Semple, RK; Thompson, EL; Topaloglu, AK; Yeo, GS | 1 |
| Clifton, DK; Maeda, K; Mogi, K; Mori, Y; Murata, K; Nakada, T; Navarro, VM; Ohkura, S; Okamura, H; Steiner, RA; Tsukamura, H; Wakabayashi, Y | 1 |
| Coolen, LM; Goodman, RL; Lehman, MN | 2 |
| Bloom, SR; Caraty, A; Ciofi, P; Dhillo, WS; Ghatei, MA; Horvath, MC; Hrabovszky, E; Kallo, I; Keller, E; Liposits, Z; Vida, B | 1 |
| Kotan, LD; Topaloglu, AK | 1 |
| Ali, B; Amin, NA; Ciofi, P; Plant, TM; Ramaswamy, S; Seminara, SB | 1 |
| Dhillo, WS; Jayasena, CN | 1 |
| Cholanian, M; Dacks, PA; Krajewski, SJ; Rance, NE; Smith, MA | 1 |
| Latronico, AC; Silveira, LG; Tusset, C | 1 |
| Maeda, K; Ohkura, S; Oka, Y; Okamura, H; Tsukamura, H; Uenoyama, Y; Wakabayashi, Y | 1 |
| Ciofi, P; Grove, KL; Kirigiti, M; Smith, MS; True, C | 1 |
| Castellano, JM; Clifton, DK; McConkey, SM; Navarro, VM; Pineda, R; Pinilla, L; Ruiz-Pino, F; Steiner, RA; Tena-Sempere, M | 1 |
| Navarro, VM; Tena-Sempere, M | 2 |
| Plant, TM; Ramaswamy, S; Seminara, SB | 1 |
| Alreja, M; Bosch, MA; Braun, RE; Clifton, DK; Dearth, A; García-Galiano, D; Gottsch, ML; Hobbs, SJ; Navarro, VM; Palmiter, RD; Pinilla, L; Ronnekleiv, OK; Steiner, RA; Tena-Sempere, M; Wu, M | 1 |
| Gereltsetseg, G; Irahara, M; Iwasa, T; Kinouchi, R; Kuwahara, A; Matsuzaki, T; Murakami, M; Yamamoto, S; Yasui, T; Yoshida, S | 1 |
| Blomenröhr, M; García-Galiano, D; Gaytan, F; Krajnc-Franken, MA; Leon, S; Manfredi-Lozano, M; Navarro, VM; Pinilla, L; Romero-Ruiz, A; Tena-Sempere, M; van Ingen Schenau, D; van Noort, PI | 1 |
| Grachev, P; Kinsey-Jones, JS; Li, XF; Lightman, SL; Lin, YS; Milligan, SR; O'Byrne, KT | 1 |
| Ichikawa, M; Maeda, K; Matsuyama, S; Mogi, K; Mori, Y; Ohkura, S; Okamura, H; Tsukamura, H; Wakabayashi, Y | 1 |
| Caraty, A; Ciofi, P; Coen, CW; Deli, L; Hrabovszky, E; Kalló, I; Liposits, Z; Molnár, CS; Vida, B | 1 |
| Kauffman, AS; Poling, MC | 1 |
| Anderson, RA; Bouligand, J; Brailly-Tabard, S; Francou, B; George, JT; Guiochon-Mantel, A; Millar, RP; Tello, JA; Young, J | 1 |
| Almeida, TA; Candenas, L; Cejudo Roman, A; Dorta, I; Hernández, M; Illanes, M; Pinto, FM; Tena-Sempere, M | 1 |
| Briscoe, AM; Davis, SM; Goodman, RL; Hileman, SM; Nestor, CC; Valent, M | 1 |
| Ciofi, P; Krajewski-Hall, SJ; Lai, J; McMullen, NT; Mittelman-Smith, MA; Rance, NE; Williams, H | 1 |
| Iijima, N; Matsumoto, K; Ozawa, H; Sawai, N; Takumi, K | 1 |
| Kinsey-Jones, JS; Li, XF; Lin, YS; O'Byrne, KT | 1 |
| Berberoğlu, M; Cesur, Y; Demirbilek, H; Doğan, M; Dökmetaş, S; Gürbüz, F; Güven, A; Kekil, MB; Kılıçlı, MF; Kirel, B; Kotan, LD; Mengen, E; Önenli Mungan, N; Özbek, MN; Özen, S; Poyrazoğlu, Ş; Saka, N; Şıklar, Z; Temiz, F; Topaloğlu, AK; Yüksel, B | 1 |
| Aguilar, E; Dieguez, C; Millar, RP; Pinilla, L; Tena-Sempere, M | 1 |
| Carroll, RS; Clifton, DK; Gill, JC; Kaiser, UB; Kwong, C; Martin, C; Navarro, VM; Noel, SD; Steiner, RA; Xu, S | 1 |
| Bouret, SG; Caron, E; Ciofi, P; Prevot, V | 1 |
| Bloom, SR; Borsay, BÁ; Ciofi, P; Dhillo, WS; Gergely, P; Ghatei, MA; Herczeg, L; Hrabovszky, E; Liposits, Z; Molnár, CS; Sipos, MT | 1 |
| di Domenico, AL; Grachev, P; Kinsey-Jones, JS; Li, XF; Lightman, SL; Millar, RP; O'Byrne, KT | 1 |
| Mori, Y; Murata, K; Ohkura, S; Okamura, H; Sakamoto, K; Takeuchi, Y; Wakabayashi, Y; Yayou, K | 1 |
| Tena-Sempere, M | 2 |
| Billings, HJ; Coolen, LM; Drews, S; Goodman, RL; Hileman, SM; Lehman, MN; Merkley, CM; Porter, KL | 1 |
| Aguilar, E; Castellano, JM; García-Galiano, D; Navarro, VM; Pineda, R; Pinilla, L; Roa, J; Ruiz-Pino, F; Sánchez-Garrido, MA; Tena-Sempere, M | 1 |
| Bloom, SR; Borsay, BÁ; Ciofi, P; Dhillo, WS; Ghatei, MA; Herczeg, L; Hrabovszky, E; Liposits, Z; Molnár, CS; Rácz, K; Sipos, MT; Vida, B | 1 |
| Elsamani, L; Grachev, P; Hu, MH; Li, XF; Lightman, SL; Lin, YS; Millar, RP; O'Byrne, KT; Paterson, SJ | 1 |
| Gore, AC; Kirson, D; Perez, LF; Walker, DM | 1 |
| Mori, Y; Okamura, H; Sakamoto, K; Wakabayashi, Y; Yamamura, T | 1 |
| Krajewski-Hall, SJ; McMullen, NT; Mittelman-Smith, MA; Rance, NE; Williams, H | 1 |
| Deura, C; Ieda, N; Maeda, K; Minabe, S; Mostari, P; Tsukamura, H; Uenoyama, Y; Yamada, S | 1 |
| Goodman, RL; Hileman, SM; Lehman, MN | 1 |
| Maeda, K; Ohkura, S; Okamura, H; Tsukamura, H; Uenoyama, Y; Wakabayashi, Y | 1 |
| Navarro, VM | 2 |
| Alreja, M | 1 |
| Boehm, U; de Croft, S; Herbison, AE | 1 |
| Burger, LL; Moenter, SM; Ruka, KA | 2 |
| Bedecarrats, GY; Joseph, NT; Millar, RP; Tello, JA | 1 |
| Millar, RP; Newton, CL | 1 |
| Dacks, PA; Krajewski-Hall, SJ; Mittelman-Smith, MA; Rance, NE; Romanovsky, AA | 1 |
| Lippincott, MF; Seminara, SB; True, C | 1 |
| Cernea, M; Connors, JM; Coolen, LM; Goodman, RL; Hardy, SL; Hileman, SM; Lehman, MN; Millar, RP; Nestor, CC; Porter, KL | 1 |
| Bloom, SR; Borsay, BÁ; Ciofi, P; Dhillo, WS; Ghatei, MA; Herczeg, L; Hrabovszky, E; Liposits, Z; Rácz, K | 1 |
| Mori, Y; Okamura, H; Sakamoto, K; Takeuchi, Y; Tanaka, T; Wakabayashi, Y; Yamamura, T | 1 |
| Grachev, P; Millar, RP; O'Byrne, KT | 1 |
| Millar, RP | 1 |
| Iijima, N; Matsuzaki, T; Ozawa, H; Sawai, N | 1 |
| Cui, Y; Liu, J; Yan, X; Yuan, C; Zhao, N | 1 |
| Maeda, K; Tsukamura, H; Uenoyama, Y | 1 |
| Bartzen-Sprauer, J; Ciofi, P; Klosen, P; Mikkelsen, JD; Simonneaux, V | 1 |
| Castellano, JM; Mikkelsen, JD; Overgaard, A; Ruiz-Pino, F; Tena-Sempere, M | 1 |
| Bloom, SR; Borsay, BÁ; Ciofi, P; Dhillo, WS; Ghatei, MA; Herczeg, L; Hrabovszky, E; Liposits, Z; Skrapits, K | 2 |
| Cui, P; Fang, F; Hua, W; Jiang, S; Li, F; Liu, Y; Luo, L; Song, M; Song, S; Tian, Y | 1 |
| Almeida, TA; Candenas, L; Cejudo-Román, A; Fernández-Sánchez, M; García-Ortega, J; Hernández, M; Pinto, FM; Prados, N; Romero, M; Tena-Sempere, M | 1 |
| Garcia-Galiano, D; Leon, S; Manfredi-Lozano, M; Navarro, VM; Pinilla, L; Roa, J; Ruiz-Pino, F; Sánchez-Garrido, MA; Tena-Sempere, M | 1 |
| Ahn, T; Coolen, LM; Fergani, C; Lehman, MN; Padmanabhan, V | 1 |
| Abacı, A; Anık, A; Böber, E; Çalan, ÖG; Çatlı, G; Dündar, BN; Küme, T | 1 |
| Cholanian, M; Krajewski-Hall, SJ; McMullen, NT; Rance, NE | 1 |
| Clarke, IJ; Li, Q; Millar, RP; Smith, JT | 1 |
| Coolen, LM; Goodman, RL; Lehman, MN; Merkley, CM | 1 |
| Chavkin, C; Clifton, DK; Ferrara, LK; Oakley, AE; Reed, SD; Steiner, RA | 1 |
| Cernea, M; Coolen, LM; Goodman, RL; Lehman, MN; Padmanabhan, V | 1 |
| Flynn, FW; Pitynski, D; Skinner, DC | 1 |
| Ishihara, T; Kanasaki, H; Kyo, S; Mijiddorj, T; Oride, A; Sukhbaatar, U | 1 |
| Anselmo-Franci, JA; Bertram, R; Carolino, RO; Helena, CV; Kalil, B; Pogrebna, VV; Stathopoulos, AM; Toporikova, N | 1 |
| Leng, G; Ludwig, M; Millar, RP; Pineda, R; Sabatier, N | 1 |
| Castellano, JM; Lomniczi, A; Matagne, V; Ojeda, SR; Plant, TM; Ramaswamy, S; Toro, CA; Wright, H | 1 |
| Iwata, K; Murakawa, H; Ozawa, H; Takeshita, T | 1 |
| Anderson, RC; Millar, RP; Newton, CL | 1 |
| Alexiadis, M; Fuller, PJ; Hannan, NJ; Hastie, R; Kaitu'u-Lino, TJ; McNamara, H; Tong, S; Tuohey, L; Vickers, DK; Walker, SP; Whitehead, CL | 1 |
| Krajewski-Hall, SJ; McMullen, NT; Mittelman-Smith, MA; Rance, NE | 1 |
| Hassaneen, A; Ieda, N; Inoue, N; Kimura, K; Maeda, KI; Matsuda, F; Matsuyama, S; Naniwa, Y; Ohkura, S; Suetomi, Y; Tsukamura, H; Uenoyama, Y | 1 |
| Abbara, A; Bassett, P; Bloom, SR; Comninos, AN; Dhillo, WS; Jayasena, CN; Mizamtsidi, M; Narayanaswamy, S; Papadopoulou, DA; Prague, JK; Shah, AJ; Veldhuis, JD | 1 |
| Chrousos, GP; Livadas, S | 1 |
| Roepke, TA; Snyder, M; Yang, JA; Yasrebi, A | 1 |
| Cernea, M; Coolen, LM; Lehman, MN; Padmanabhan, V; Phillips, R | 1 |
| Kelly, MJ; Nestor, CC; Padilla, SL; Palmiter, RD; Qiu, J; Rønnekleiv, OK; Zhang, C | 1 |
| Prevot, V; Shruti, S | 1 |
| Anderson, RA; George, JT; Millar, RP; Skorupskaite, K; Veldhuis, JD | 4 |
| Coolen, LM; Fergani, C; Goodman, RL; Grachev, P; Hardy, SL; Lehman, MN; Mazzella, L; McCosh, RB; Newcomb, N | 1 |
| Ishigami, A; Iwata, K; Kunimura, Y; Ozawa, H | 1 |
| Adachi, K; Chatkupt, T; Davidson, BL; Dissen, GA; Lomniczi, A; Nakai, H; Ojeda, SR | 1 |
| Çelmeli, G; Ellidağ, HY; Parlak, AE; Parlak, M; Türkkahraman, D; Yılmaz, N | 1 |
| Dudek, M; Kołodziejski, PA; Pruszyńska-Oszmałek, E; Sliwowska, JH; Ziarniak, K | 1 |
| Clarke, IJ; Coolen, LM; Goodman, RL; Lehman, MN; Smith, J; Weems, P | 1 |
| Iwata, K; Kunimura, Y; Matsumoto, K; Ozawa, H | 1 |
| Blumenfeld, Z | 1 |
| Goto, T; Hirabayashi, M; Ieda, N; Ikegami, K; Inoue, N; Maeda, KI; Maturana, AD; Minabe, S; Nakamura, S; Oishi, S; Sanbo, M; Sugimoto, A; Tsukamura, H; Uenoyama, Y | 1 |
| Dobson, H; Fergani, C; Jones, DN; Pickavance, LC; Routly, JE; Smith, RF | 1 |
| Janahmadi, M; Khazali, H; Mahmoudi, F; Salehi, MS | 1 |
| DeFazio, RA; Johnson, ML; Moenter, SM; Moya, MR; Vanacker, C | 1 |
| Garcia, JP; Guerriero, KA; Keen, KL; Kenealy, BP; Seminara, SB; Terasawa, E | 1 |
| Iwata, K; Kanaya, M; Ozawa, H | 1 |
| Clarke, IJ; Henry, BA; Li, Q; Millar, RP | 1 |
| Chanson, P; Christin-Maître, S; Maione, L; Young, J | 1 |
| Irahara, M; Iwasa, T; Matsuzaki, T; Mayila, Y; Yanagihara, R; Yano, K | 1 |
| Iwata, K; Nakao, K; Ozawa, H; Takeshita, T | 1 |
| Baek, JW; Hwang, IT; Kang, MJ; Oh, YJ; Shim, YS; Yang, S | 1 |
| Coolen, LM; Goodman, RL; Lehman, MN; Lucas, KA; Moore, AM | 1 |
| Bedenbaugh, MN; Coolen, LM; Goodman, RL; Hileman, SM; Lehman, MN; Nestor, CC | 1 |
| Czyzyk, A; Genazzani, AD; Genazzani, AR; Meczekalski, B; Podfigurna, A; Szeliga, A | 1 |
| Garcia, JP; Keen, KL; Kenealy, BP; Seminara, SB; Terasawa, E | 1 |
| Khoradmehr, A; Mohammad Reza, JS; Saedi, S; Tamadon, A | 1 |
| Coolen, LM; Goodman, RL; Lehman, MN; Moore, AM; Porter, DT | 1 |
| Coolen, LM; Goodman, RL; Hardy, S; Hileman, SM; Lehman, MN; McCosh, RB; Weems, PW | 1 |
| Adams, H; Berry, ED; Clapper, JA; Foote, AP; Freking, BA; Lents, CA; Nonneman, DJ; Oliver, WT; Petersen, SL; Prezotto, LD; Thorson, JF; Wright, EC | 1 |
| Khajehnasiri, N; Khazali, H; Sheikhzadeh, F | 1 |
| Hosseini, A; Khazali, H | 1 |
| Chung, MJ; Chung, Y; Jun, Y; Kim, E | 1 |
| Kallό, I; Kołodziejski, PA; Pruszyńska-Oszmałek, E; Śliwowska, JH; Ziarniak, K | 1 |
| Blasco, V; Candenas, L; Fernández-Atucha, A; Fernández-Sánchez, M; Pinto, FM; Prados, N; Tena-Sempere, M | 1 |
| Colledge, WH; Herbison, AE; Kane, G; Piet, R; Schafer, D | 1 |
| Fergani, C; Leon, S; Navarro, VM; Padilla, SL; Palmiter, RD; Verstegen, AM | 1 |
| Anderson, RA; Sassarini, J; Skorupskaite, K | 1 |
| Blackmore, EM; Krajewski-Hall, SJ; McMullen, NT; Miranda Dos Santos, F; Rance, NE | 1 |
| Inoue, N; Magata, F; Matsuda, F; Minabe, S; Ozawa, H; Sato, M; Tsukamura, H; Uenoyama, Y; Watanabe, Y | 1 |
| Arlt, W; Chan, YM; Cole, TR; Farooqi, IS; Fergani, C; Hall, JE; Jones, CM; León, S; Lippincott, MF; Navarro, VM; Seminara, SB; Shaw, ND; Stewart, SE; Talbi, R; Terasawa, E | 1 |
| Inoue, N; Majarune, S; Nagae, M; Nima, P; Sugimoto, A; Tsukamura, H; Uenoyama, Y | 1 |
| Plant, TM | 1 |
| Cobern, JA; Coolen, LM; Goodman, RL; Lehman, MN; Moore, AM; Padmanabhan, V; Porter, DT | 1 |
| Fergani, C; Gerutshang, A; León, S; Maguire, CA; Navarro, VM; Simavli, S; Talbi, R | 1 |
| Bedenbaugh, MN; Bowdridge, EC; Coolen, LM; Goodman, RL; He, W; Hileman, SM; Lehman, MN; Lopez, JA; McCosh, RB | 1 |
| Coolen, LM; Lehman, MN; Moore, AM | 2 |
| De Burgh, R; Lass, G; Li, XF; Lightman, SL; O'Byrne, KT; Tsaneva-Atanasova, K; Voliotis, M | 1 |
| Alfaia, C; Colledge, WH; Franceschini, I; Guillaume, D; Levern, Y; Poissenot, K; Robert, V; Yeo, SH | 1 |
| Bala, G; Meczekalski, B; Podfigurna, A; Szeliga, A | 2 |
| Dhillo, WS | 3 |
| Garcia, JP; Keen, KL; Seminara, SB; Terasawa, E | 1 |
| Coolen, LM; Goodman, RL; He, W; Lehman, MN; Levine, JE | 1 |
| Abbara, A; Hunjan, T | 1 |
| Barroso, A; Roa, J; Tena-Sempere, M | 1 |
| Amodei, R; Coolen, LM; Corder, KR; Estill, CT; Gribbin, K; He, W; Jonker, SS; Lehman, MN; Lindgren, I; Roselli, CE; Stormshak, F; Whitler, W | 1 |
| Esparza, LA; Ho, BS; Kauffman, AS; Schafer, D; Thackray, VG | 1 |
| Clarke, IJ; Henry, B; Li, Q; Pereira, A; Rao, A; Smith, JT | 1 |
| Azizi, V; Hosseini, A; Khazali, H; Oryan, S | 1 |
| Herbison, AE; Hessler, S; Liu, X | 1 |
| Abreu, AP; Aylwin, CF; Bosch, MA; Carroll, RS; Eren, A; Kaiser, UB; Latronico, AC; Liang, JN; Lomniczi, A; Navarro, VM; Ojeda, S; Rønnekleiv, OK; Song, YB; Toro, CA | 1 |
| Inoue, N; Matsuda, F; Matsuyama, S; Munetomo, A; Ohkura, S; Sonoda, S; Suetomi, Y; Takeuchi, Y; Tatebayashi, R; Tsukamura, H; Uenoyama, Y | 1 |
| Bedenbaugh, MN; Bowdridge, EC; Goodman, RL; Haller, M; Hileman, SM; Lehman, MN; Lindo, AN; Lopez, JA; McCosh, RB; Metzger, M | 1 |
| Blasco, V; Candenas, L; Fernández-Atucha, A; Fernández-Sánchez, M; González-Ravina, C; Pinto, FM | 1 |
| Chatzicharalampous, C | 1 |
| Dudek, M; Kalló, I; Kołodziejski, PA; Pruszyńska-Oszmałek, E; Śliwowska, JH; Ziarniak, K | 1 |
| Abbara, A; Dhillo, WS; Phylactou, M | 1 |
| Cheng, L; Dong, H; Huang, D; Wang, Z; Yang, L; Yi, P | 1 |
| Goto, T; Hirabayashi, M; Ikegami, K; Inoue, N; Kobayashi, K; Majarune, S; Nagae, M; Nakamura, S; Okamoto, S; Sanbo, M; Tsuchida, H; Tsukamura, H; Uenoyama, Y | 1 |
| Atay, E; Atay, Z; Cakici, C; Ceran, O; Kılınç, S; Turan, M; Ulfer, G; Yigitbasi, T | 1 |
| Iwata, K; Minabe, S; Ozawa, H; Tsuchida, H; Tsukamura, H | 1 |
| Bedenbaugh, MN; Bowdridge, EC; Fergani, C; Freking, BA; Hileman, SM; Lehman, MN; Lents, CA; Lindo, AN; Lopez, JA; McCosh, RB; Meadows, LJ; Thorson, JF; Young, SA | 1 |
| Abbara, A; Dhillo, WS | 1 |
| Bakker, J | 1 |
| Anderson, RA; Skorupskaite, K | 1 |
| Coolen, LM; Lehman, MN; Lohr, DB; Moore, AM | 1 |
| Chaudhry, N; Khan, SH | 1 |
| Inoue, N; Nagae, M; Tsuchida, H; Tsukamura, H; Uenoyama, Y | 1 |
| Okamura, H; Wakabayashi, Y; Yamamura, T | 2 |
| Harlow, K; Knauer, MT; Lents, CA; Nestor, CC; Renwick, AN; Shuping, SL; Sommer, JR | 1 |
| Goto, T; Ikegami, K; Inoue, N; Nakamura, S; Tsukamura, H; Uenoyama, Y; Watanabe, Y | 1 |
| Anderson, RA; Millar, RP | 1 |
| Seminara, SB; Topaloglu, AK | 1 |
| Andrés Cortasa, S; Berta Dorfman, V; Daniel Vitullo, A; Fidel, V; Halperin, J; Ignacio Felipe Inserra, P; Proietto, S; Raúl Schmidt, A | 1 |
| Enomoto, H; Iwata, K; Matsumoto, K; Morita, A; Otsuka, M; Ozawa, H | 1 |
| Lettieri, A; Magni, P; Nur Demirci, T; Passarelli, A | 1 |
| Goodman, RL; Herbison, AE; Lehman, MN; Navarro, VM | 1 |
| Harlow, K; Merkley, CM; Nestor, CC; Renwick, AN; Shuping, SL; Sommer, JR | 1 |
| Doneray, H; Guzelkas, I; Orbak, Z; Ozturk, N; Sagsoz, N | 1 |
| Hajbos, M; Kostrzak, A; Kucharski, M; Maciejewska-Jeske, M; Meczekalski, B; Niwczyk, O; Rudnicka, E; Smolarczyk, R; Szeliga, A | 1 |
| Terasawa, E | 1 |
| Griesgraber, MJ; Griffith, EH; Harlow, K; Hileman, SM; Nestor, CC; Seman, AD; Shuping, SL; Sommer, JR | 1 |
| Lehman, MN | 1 |
| Kanasaki, H; Kyo, S; Okada, H; Oride, A; Tumurbaatar, T; Tumurgan, Z | 1 |
| Arora, T; Parkash, J; Prashar, V; Sharma, A; Singh, R | 1 |
| Abot, A; Dardente, H; Dufourny, L; Duittoz, A; Fleurot, R; Froment, P; Hellier, V; Knauf, C; Robert, V | 1 |
| Carroll, RS; Chouman, S; Johnson, M; Johnson, T; Kaiser, UB; Naulé, L; Navarro, VM; Roberts, SA | 1 |
| Coimbra, CC; Costa, SP; da Costa Silva, KS; Dias Peixoto, MF; Diniz E Magalhães, CO; Domingues, TE; Ferreira da Fonseca, S; Henriques, PC; Lacerda, ACR; Mendonça, VA; Reis, AM; Rodrigues, CM; Sampaio, KH; Scheidet, PHF; Silva, SB; Szawka, RE | 1 |
| Coutinho, EA; Esparza, LA; Hudson, AD; Kauffman, AS; Rizo, N; Steffen, P | 1 |
| Dhillo, WS; Mills, EG | 1 |
| Almeida, FRCL; Araujo-Lopes, R; Campideli-Santana, AC; Gusmao, DO; Szawka, RE | 1 |
| Constantin, S | 1 |
| Ueta, Y | 1 |
| Abaraonye, I; Abbara, A; Bartram, S; Charalambides, MM; Koysombat, K; Lancaster, A; Murthy, S; Patel, B; Petitt, T; Pradeep, A; Stevenson, H; Vineall, O | 1 |
| Ishii, H; Iwata, K; Matsuda, F; Ogata, R; Ozawa, H; Sato, M | 1 |
| Moore, AM | 1 |
| Guru, S; Han, SY; Herbison, AE; Kim, JC; McQuillan, HJ; Morris, PG; Pardo-Navarro, M; Yeo, SH | 1 |
| Chen, Y; Hu, J; Li, J; Li, X; Li, Z; Xu, G; Zhao, X | 1 |
| Ciftci, N; Demirbilek, H; Vuralli, D | 1 |
| Goodman, RL; Hileman, SM; Lehman, MN; Merkley, CM; Nestor, CC | 1 |
| Kimura, K; Matsuyama, S; Minabe, S; Nakamura, S; Ohkura, S | 1 |
| Tsukamura, H; Uenoyama, Y | 1 |
| Aerts, EG; Agus, S; Bowdridge, EC; Coolen, LM; Goodman, RL; Griesgraber, MJ; Hardy, SL; Hileman, SM; Lehman, MN; Moore, AM; Onslow, K; Walters, BA | 1 |
| Herbison, AE; Morris, PG | 1 |
| Enomoto, Y; Hirabayashi, M; Inoue, N; Kometani, M; Matsunaga, N; Matsuzaki, S; Nagae, M; Nonogaki, M; Panthee, A; Takizawa, M; Tsuchida, H; Tsukamura, H; Uenoyama, Y; Yamada, K | 1 |
53 review(s) available for neurokinin b and kiss1 protein, human
| Article | Year |
|---|---|
The recent genetics of hypogonadotrophic hypogonadism - novel insights and new questions.
Topics: Consanguinity; Extracellular Matrix Proteins; Female; Fibroblast Growth Factor 8; Gastrointestinal Hormones; Gonads; Humans; Hypogonadism; Hypothalamo-Hypophyseal System; Kallmann Syndrome; Kisspeptins; Male; Nerve Tissue Proteins; Neurokinin B; Neuropeptides; Phenotype; Receptor, Fibroblast Growth Factor, Type 1; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Receptors, Peptide; Sexual Maturation; Tumor Suppressor Proteins | 2010 |
Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Feedback, Physiological; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Models, Biological; Neurokinin B; Periodicity; Tumor Suppressor Proteins | 2010 |
Molecular causes of hypogonadotropic hypogonadism.
Topics: Animals; Female; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Hypothalamo-Hypophyseal System; Kisspeptins; Male; Mice; Neurokinin B; Pituitary-Adrenal System; Puberty; Puberty, Delayed; Tumor Suppressor Proteins | 2010 |
Neurokinin B and the hypothalamic regulation of reproduction.
Topics: Aging; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Female; Gene Expression; Humans; Hypothalamus; Kisspeptins; Macaca mulatta; Male; Neurokinin B; Neurons; Postmenopause; Pregnancy; Receptors, Neurokinin-3; Reproduction; Sex Characteristics; Signal Transduction; Terminology as Topic; Tumor Suppressor Proteins | 2010 |
Impact of mutations in kisspeptin and neurokinin B signaling pathways on human reproduction.
Topics: Amino Acid Sequence; Animals; Female; Gonads; Humans; Kisspeptins; Male; Molecular Sequence Data; Neurokinin B; Puberty, Precocious; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Reproduction; Signal Transduction; Tumor Suppressor Proteins | 2010 |
Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus.
Topics: Animals; Dynorphins; Environment; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurobiology; Neurokinin B; Neurons; Steroids; Tumor Suppressor Proteins | 2010 |
Kisspeptins and the neuroendocrine control of reproduction.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Neurosecretory Systems; Neurotransmitter Agents; Reproduction; Tumor Suppressor Proteins | 2011 |
Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility.
Topics: Animals; Fertility; Humans; Kisspeptins; Metabolic Networks and Pathways; Models, Biological; Neurokinin B; Neurosecretory Systems; Puberty; Reproduction; Sex Differentiation | 2011 |
Kisspeptins and reproduction: physiological roles and regulatory mechanisms.
Topics: Animals; Dynorphins; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Hypothalamus; Kisspeptins; Male; Neural Pathways; Neurokinin B; Puberty; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reproduction; Sex Differentiation; Signal Transduction | 2012 |
Deciphering puberty: novel partners, novel mechanisms.
Topics: Animals; Humans; Kisspeptins; Leptin; Neurokinin B; Neurosecretory Systems; Puberty | 2012 |
Neuroanatomy of the kisspeptin signaling system in mammals: comparative and developmental aspects.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Axons; Dynorphins; Galanin; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Preoptic Area; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Signal Transduction; Third Ventricle | 2013 |
Kisspeptin and GnRH pulse generation.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Goats; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Male; Neurokinin B; Neurons; Ovulation; Spermatogenesis | 2013 |
Electrophysiology of kisspeptin neurons.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrous Cycle; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Kisspeptins; Male; Mice; N-Methylaspartate; Neurokinin B; Neurons; Reproduction | 2013 |
Reproductive neuropeptides: prevalence of GnRH and KNDy neural signalling components in a model avian, gallus gallus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Chickens; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neuropeptides; Reproduction | 2013 |
Current and future applications of GnRH, kisspeptin and neurokinin B analogues.
Topics: Animals; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B | 2013 |
Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: a novel hypothesis on the mechanism of hot flushes.
Topics: Animals; Body Temperature Regulation; Dynorphins; Estradiol; Estrous Cycle; Female; Hot Flashes; Humans; Hypothalamus; Kisspeptins; Luteinizing Hormone; Models, Biological; Neurokinin B; Neurons; Ovariectomy; Postmenopause; Preoptic Area; Rats; Receptors, Neurokinin-3; Signal Transduction; Skin; Tail; Vasodilation | 2013 |
Use of genetic models of idiopathic hypogonadotrophic hypogonadism in mice and men to understand the mechanisms of disease.
Topics: Animals; Disease Models, Animal; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Kisspeptins; Mice; Neurokinin B; Signal Transduction | 2013 |
Keeping puberty on time: novel signals and mechanisms involved.
Topics: Age Factors; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Gene Regulatory Networks; Humans; Hypothalamus; Kisspeptins; Leptin; MicroRNAs; Models, Biological; Neurokinin B; Neurons; Puberty; Signal Transduction | 2013 |
A role for neurokinin B in pulsatile GnRH secretion in the ewe.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Neurons; Receptors, Neurokinin-3; Sheep; Signal Transduction | 2014 |
The role of neurokinin B signalling in reproductive neuroendocrinology.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Kisspeptins; Luteinizing Hormone; Male; Mice; Neuroendocrinology; Neurokinin B; Pituitary-Adrenal System; Rats; Reproduction; Signal Transduction | 2014 |
KNDy neuron as a gatekeeper of puberty onset.
Topics: Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Neurons; Puberty; Sexual Maturation | 2014 |
Therapeutic Neuroendocrine Agonist and Antagonist Analogs of Hypothalamic Neuropeptides as Modulators of the Hypothalamic-Pituitary-Gonadal Axis.
Topics: Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Gonads; Humans; Hypothalamo-Hypophyseal System; Kisspeptins; Neurokinin B | 2016 |
Control of the onset of puberty.
Topics: Animals; Dynorphins; Estradiol; Gene Expression Regulation, Developmental; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neuropeptides; Pituitary Gland; Puberty; Sexual Maturation | 2016 |
Investigational and experimental GnRH analogs and associated neurotransmitters.
Topics: Drugs, Investigational; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Kisspeptins; Male; Neurokinin B | 2017 |
Topics: Animals; Female; Gonadotrophs; Gonadotropin-Releasing Hormone; Gonads; Hormone Antagonists; Humans; Hypogonadism; Hypothalamo-Hypophyseal System; Kisspeptins; Male; Menopause; Neurokinin B; Pituitary-Adrenal System; Sexual Maturation | 2017 |
Regulation of GnRH pulsatility in ewes.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Breeding; Dynorphins; Estradiol; Estrous Cycle; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Homeostasis; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Periodicity; Progesterone; Seasons; Sexual Maturation; Sheep | 2018 |
The role of kisspeptin/neurokinin B/dynorphin neurons in pathomechanism of vasomotor symptoms in postmenopausal women: from physiology to potential therapeutic applications.
Topics: Dynorphins; Feedback, Physiological; Female; Hot Flashes; Humans; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Postmenopause; Vasomotor System | 2018 |
The role of neuropeptides and neurotransmitters on kisspeptin/kiss1r-signaling in female reproduction.
Topics: Animals; Dynorphins; Female; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Receptors, Kisspeptin-1; Reproduction; Signal Transduction | 2018 |
KNDy Cells Revisited.
Topics: Animals; Dynorphins; Estrogens; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Progesterone; Reproduction; Testosterone | 2018 |
The neurokinin B pathway in the treatment of menopausal hot flushes.
Topics: Female; Gonadotropin-Releasing Hormone; Gonadotropins; Hot Flashes; Humans; Kisspeptins; Menopause; Neurokinin B; Randomized Controlled Trials as Topic; Receptors, Neurokinin-3; Treatment Outcome | 2019 |
The neurobiological mechanism underlying hypothalamic GnRH pulse generation: the role of kisspeptin neurons in the arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Mice; Neurokinin B; Neurons | 2019 |
Kisspeptin and neurokinin B analogs use in gynecological endocrinology: where do we stand?
Topics: Female; Humans; Infertility, Female; Kisspeptins; Neurokinin B; Neurons; Ovulation Induction; Puberty | 2020 |
Role of Kisspeptin and NKB in Puberty in Nonhuman Primates: Sex Differences.
Topics: Animals; Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Macaca mulatta; Male; Neurokinin B; Puberty; Sex Characteristics; Signal Transduction | 2019 |
Does the KNDy Model for the Control of Gonadotropin-Releasing Hormone Pulses Apply to Monkeys and Humans?
Topics: Animals; Dynorphins; Female; Gonadotropin-Releasing Hormone; Haplorhini; Humans; Hypothalamus; Kisspeptins; Male; Neurokinin B | 2019 |
Clinical Translational Studies of Kisspeptin and Neurokinin B.
Topics: Animals; Female; Fertilization in Vitro; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Male; Neurokinin B; Reproduction; Translational Research, Biomedical | 2019 |
Neuropeptide Control of Puberty: Beyond Kisspeptins.
Topics: Animals; Humans; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Neuropeptides; Puberty; Reproduction; Sexual Maturation; Signal Transduction | 2019 |
Metabolic regulation of kisspeptin - the link between energy balance and reproduction.
Topics: Animals; Dynorphins; Energy Metabolism; Female; Gonadotropin-Releasing Hormone; Homeostasis; Humans; Hypothalamo-Hypophyseal System; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Ovary; Puberty; Reproduction | 2020 |
Kisspeptin and neurokinin B expression in the human hypothalamus: Relation to reproduction and gender identity.
Topics: Female; Gender Identity; Humans; Hypothalamus; Kisspeptins; Male; Neurokinin B; Reproduction | 2021 |
Hypothalamic neurokinin signalling and its application in reproductive medicine.
Topics: Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Male; Neurokinin B; Reproductive Medicine | 2022 |
Beyond GnRH, LH and FSH: The role of kisspeptin on hypothalalmic-pituitary gonadal (HPG) axis pathology and diagnostic consideration.
Topics: Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Neurokinin B | 2021 |
Role of KNDy Neurons Expressing Kisspeptin, Neurokinin B, and Dynorphin A as a GnRH Pulse Generator Controlling Mammalian Reproduction.
Topics: Animals; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Mammals; Neurokinin B; Neurons; Reproduction | 2021 |
Cellular and molecular mechanisms regulating the KNDy neuronal activities to generate and modulate GnRH pulse in mammals.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Mammals; Neurokinin B; Neurons | 2022 |
The roles of kisspeptin and neurokinin B in GnRH pulse generation in humans, and their potential clinical application.
Topics: Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Receptors, Neurokinin-3 | 2022 |
Review of human genetic and clinical studies directly relevant to GnRH signalling.
Topics: Animals; Gonadotropin-Releasing Hormone; Human Genetics; Humans; Kisspeptins; Ligands; Mammals; Neurokinin B | 2022 |
Neuroendocrine control of gonadotropin-releasing hormone: Pulsatile and surge modes of secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dendrimers; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Mice; Neurokinin B; Rats; Sheep | 2022 |
Neuroendocrine Determinants of Polycystic Ovary Syndrome.
Topics: Acetylcholine; Dopamine; Female; Galanin; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurotransmitter Agents; Polycystic Ovary Syndrome; Serotonin; United States | 2022 |
The mechanism underlying the pubertal increase in pulsatile GnRH release in primates.
Topics: Animals; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Primates; Sexual Maturation | 2022 |
Hypothalamic Kisspeptin Neurons: Integral Elements of the GnRH System.
Topics: Arcuate Nucleus of Hypothalamus; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Polycystic Ovary Syndrome | 2023 |
Invited review: Translating kisspeptin and neurokinin B biology into new therapies for reproductive health.
Topics: Animals; Biology; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Male; Mammals; Neurokinin B; Reproduction; Reproductive Health | 2022 |
Targeting KNDy neurons to control GnRH pulses.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neurons | 2022 |
Kisspeptin-neuron control of LH pulsatility and ovulation.
Topics: Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons | 2022 |
KNDy neurons as the GnRH pulse generator: Recent studies in ruminants.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neurons; Ruminants | 2023 |
KNDy neurones and GnRH/LH pulse generation: Current understanding and future aspects.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Mammals; Neurokinin B; Neurons; Reproduction | 2023 |
5 trial(s) available for neurokinin b and kiss1 protein, human
| Article | Year |
|---|---|
Kisspeptin restores pulsatile LH secretion in patients with neurokinin B signaling deficiencies: physiological, pathophysiological and therapeutic implications.
Topics: Adult; Disorders of Sex Development; Estradiol; Female; Humans; Inhibins; Kisspeptins; Luteinizing Hormone; Male; Mutation; Neurokinin B; Pulsatile Flow; Receptors, Neurokinin-3; Signal Transduction; Testosterone | 2013 |
κ Agonists as a novel therapy for menopausal hot flashes.
Topics: Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hot Flashes; Humans; Kisspeptins; Luteinizing Hormone; Middle Aged; Neurokinin B; Neurons; Pentazocine; Placebos; Postmenopause; Receptors, Opioid, kappa | 2015 |
Interactions Between Neurokinin B and Kisspeptin in Mediating Estrogen Feedback in Healthy Women.
Topics: Adolescent; Adult; Cross-Over Studies; Estradiol; Estrogens; Feedback, Physiological; Female; Humans; Kisspeptins; Luteinizing Hormone; Middle Aged; Neurokinin B; Neurotransmitter Agents; Receptors, Tachykinin; Signal Transduction; Young Adult | 2016 |
Kisspeptin and neurokinin B interactions in modulating gonadotropin secretion in women with polycystic ovary syndrome.
Topics: Female; Humans; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Polycystic Ovary Syndrome | 2020 |
Female infertility is associated with an altered expression of the neurokinin B/neurokinin B receptor and kisspeptin/kisspeptin receptor systems in ovarian granulosa and cumulus cells.
Topics: Adolescent; Adult; Cumulus Cells; Female; Gene Expression; Genetic Association Studies; Granulosa Cells; Humans; Infertility, Female; Kisspeptins; Neurokinin B; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Young Adult | 2020 |
167 other study(ies) available for neurokinin b and kiss1 protein, human
| Article | Year |
|---|---|
Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; gamma-MSH; Immunohistochemistry; In Vitro Techniques; Kisspeptins; Male; Neurokinin B; Neurons; Sheep; Tumor Suppressor Proteins | 2007 |
Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback.
Topics: Aging; Animals; Dynorphins; Estrogens; Feedback, Physiological; Female; Humans; Hypothalamus; Kisspeptins; Menopause; Middle Aged; Neurokinin B; Neurons; Neurosecretory Systems; Ovary; Rats; Substance P; Tumor Suppressor Proteins | 2009 |
TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction.
Topics: Amino Acid Sequence; Chromosomes, Human, Pair 4; DNA Mutational Analysis; Family; Gonads; Humans; Hypogonadism; Kisspeptins; Models, Biological; Mutation; Neurokinin B; Neurons; Pedigree; Receptors, Neurokinin-3; Reproduction; Sequence Homology, Amino Acid; Tumor Suppressor Proteins | 2009 |
The neurokinin B pathway in human reproduction.
Topics: Gonads; Humans; Hypogonadism; Hypothalamo-Hypophyseal System; Kisspeptins; Mutation; Neurokinin B; Reproduction; Signal Transduction; Tumor Suppressor Proteins | 2009 |
Sex differences in the regulation of Kiss1/NKB neurons in juvenile mice: implications for the timing of puberty.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Data Interpretation, Statistical; Female; Gene Expression Regulation; Gonadal Steroid Hormones; In Situ Hybridization; Kisspeptins; Luteinizing Hormone; Male; Mice; Mice, Inbred C57BL; Neurokinin B; Neurons; Orchiectomy; Ovariectomy; RNA, Messenger; Sex Characteristics; Sexual Maturation; Testosterone | 2009 |
Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estradiol; Female; Gonadotropin-Releasing Hormone; In Situ Hybridization; Kisspeptins; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Neurokinin B; Neurons; Ovariectomy; Protein Precursors; Receptors, Neurokinin-3; Receptors, Opioid; RNA, Messenger; Signal Transduction; Tumor Suppressor Proteins | 2009 |
The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus: sex differences and effects of prenatal testosterone in sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Neurons; Oligopeptides; Pregnancy; Prenatal Exposure Delayed Effects; Sex Characteristics; Sheep; Testosterone | 2010 |
The effects of neurokinin B upon gonadotrophin release in male rodents.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Fasting; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Male; Mice; Mice, Inbred C57BL; Neurokinin B; Protein Precursors; Proteins; Rats; Rats, Wistar; Receptors, Tachykinin; Tachykinins | 2010 |
Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Biological Clocks; Dynorphins; Electrophysiology; Estrous Cycle; Female; Goats; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Neurosecretory Systems; Ovariectomy; Periodicity; Proteins; Reproduction; Tumor Suppressor Proteins | 2010 |
The kisspeptin system of the human hypothalamus: sexual dimorphism and relationship with gonadotropin-releasing hormone and neurokinin B neurons.
Topics: Adult; Aged; Animals; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Male; Middle Aged; Neurokinin B; Neurons; Protein Precursors; Puberty; Reproduction; Sex Characteristics; Signal Transduction; Tumor Suppressor Proteins | 2010 |
Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Drug Interactions; Gonadotropin-Releasing Hormone; Humans; Immunohistochemistry; Injections, Intravenous; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Microscopy, Confocal; Neurokinin B; Oligopeptides; Orchiectomy; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, LHRH; Receptors, Neurokinin-3; Substance P | 2010 |
Neurokinin B and kisspeptin: sexual partners or single agents?
Topics: Animals; Arcuate Nucleus of Hypothalamus; Drug Interactions; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Neurokinin B; Oligopeptides; Orchiectomy; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, Neurokinin-3; Substance P | 2010 |
Characterisation of arcuate nucleus kisspeptin/neurokinin B neuronal projections and regulation during lactation in the rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Female; Immunohistochemistry; In Situ Hybridization; Kisspeptins; Lactation; Microscopy, Confocal; Neurokinin B; Neurons; Proteins; Rats; Rats, Wistar | 2011 |
Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Estradiol; Estrous Cycle; Feedback, Physiological; Female; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Organ Specificity; Peptide Fragments; Prosencephalon; Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Neurokinin-3; RNA, Messenger; Signal Transduction; Substance P | 2011 |
Evidence from the agonadal juvenile male rhesus monkey (Macaca mulatta) for the view that the action of neurokinin B to trigger gonadotropin-releasing hormone release is upstream from the kisspeptin receptor.
Topics: Age Factors; Animals; Genitalia, Male; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Models, Animal; Neurokinin B; Orchiectomy; Receptors, G-Protein-Coupled; Receptors, Neurokinin-3; Signal Transduction | 2011 |
Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Feedback, Physiological; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Neurokinin B; Neurons; Receptors, Estrogen; Receptors, Progesterone; Signal Transduction | 2011 |
Fasting reduces the kiss1 mRNA levels in the caudal hypothalamus of gonadally intact adult female rats.
Topics: Animals; Estrous Cycle; Female; Food Deprivation; Hypothalamus; Kisspeptins; Leptin; Luteinizing Hormone; Neurokinin B; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice.
Topics: Adamantane; Animals; Dipeptides; Follicle Stimulating Hormone; Galanin-Like Peptide; Glutamic Acid; Gonadotropin-Releasing Hormone; Gonadotropins; Hypogonadism; Kisspeptins; Luteinizing Hormone; Male; Mice; Mice, Knockout; Models, Neurological; Naltrexone; Neurokinin B; Peptide Fragments; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide; Signal Transduction; Substance P; Testosterone | 2012 |
The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Narcotic Antagonists; Neurokinin B; Ovariectomy; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Receptors, Opioid; Receptors, Opioid, kappa; Signal Transduction; Substance P | 2012 |
Morphological evidence for direct interaction between kisspeptin and gonadotropin-releasing hormone neurons at the median eminence of the male goat: an immunoelectron microscopic study.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Goats; Gonadotropin-Releasing Hormone; Hypothalamus; Immunohistochemistry; Kisspeptins; Male; Median Eminence; Microscopy, Immunoelectron; Neurokinin B; Neurons; Preoptic Area | 2011 |
Co-localisation of kisspeptin with galanin or neurokinin B in afferents to mouse GnRH neurones.
Topics: Animals; Female; Fluorescent Antibody Technique; Galanin; In Situ Hybridization; Kisspeptins; Mice; Microscopy, Confocal; Neurokinin B; Neurons, Afferent; Ovariectomy | 2012 |
Sexually dimorphic testosterone secretion in prenatal and neonatal mice is independent of kisspeptin-Kiss1r and GnRH signaling.
Topics: Animals; Animals, Newborn; Female; Fetus; Gene Expression Regulation, Developmental; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Mice, Knockout; Neurokinin B; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Sex Characteristics; Signal Transduction; Testis; Testosterone | 2012 |
Analysis of the expression of neurokinin B, kisspeptin, and their cognate receptors NK3R and KISS1R in the human female genital tract.
Topics: Endometrium; Fallopian Tubes; Female; Humans; Immunohistochemistry; Kisspeptins; Neurokinin B; Ovary; Postmenopause; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sexual Maturation; Uterus | 2012 |
Evidence of a role for kisspeptin and neurokinin B in puberty of female sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Female; Gonadotropin-Releasing Hormone; Immunohistochemistry; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Neurons; Oligopeptides; Orchiectomy; Ovariectomy; Peptide Fragments; Receptors, Neurokinin-3; Sexual Maturation; Sheep; Substance P; Time Factors | 2012 |
Arcuate kisspeptin/neurokinin B/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dynorphins; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Immunohistochemistry; Immunotoxins; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Neuropeptide Y; Ovariectomy; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins | 2012 |
Immunofluorescent histochemical and ultrastructural studies on the innervation of kisspeptin/neurokinin B neurons to tuberoinfundibular dopaminergic neurons in the arcuate nucleus of rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dopaminergic Neurons; Estradiol; Female; Fluorescent Antibody Technique; Immunohistochemistry; Kisspeptins; Male; Microscopy, Electron, Transmission; Microscopy, Immunoelectron; Neural Pathways; Neurokinin B; Ovariectomy; Prolactin; Rats; Rats, Wistar; Sex Characteristics | 2012 |
High-fat diet increases LH pulse frequency and kisspeptin-neurokinin B expression in puberty-advanced female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diet, High-Fat; Female; Hypothalamus; Kisspeptins; Leptin; Luteinizing Hormone; Neurokinin B; Puberty; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Distribution of gene mutations associated with familial normosmic idiopathic hypogonadotropic hypogonadism.
Topics: Adolescent; Adult; Cohort Studies; Family Health; Genetic Association Studies; Humans; Hypogonadism; Infant; Kisspeptins; Male; Mutation; Neurokinin B; Prospective Studies; Protein Isoforms; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, LHRH; Receptors, Neurokinin-3; Tachykinins; Turkey; Young Adult | 2012 |
Increased neurokinin B (Tac2) expression in the mouse arcuate nucleus is an early marker of pubertal onset with differential sensitivity to sex steroid-negative feedback than Kiss1.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Estradiol; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Mice; Mice, Knockout; Neurokinin B; Neurons; Protein Precursors; Sexual Maturation; Signal Transduction; Tachykinins | 2012 |
Alteration in neonatal nutrition causes perturbations in hypothalamic neural circuits controlling reproductive function.
Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Brain Mapping; Female; Gene Expression Regulation, Developmental; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Litter Size; Luteinizing Hormone; Male; Malnutrition; Mice; Nerve Fibers; Nerve Net; Neurokinin B; Neurons; Nutritional Status; Ovariectomy; Overnutrition; Reproduction; Sex Factors | 2012 |
Low degree of overlap between kisspeptin, neurokinin B, and dynorphin immunoreactivities in the infundibular nucleus of young male human subjects challenges the KNDy neuron concept.
Topics: Adult; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Male; Nerve Fibers; Neurokinin B; Neurons | 2012 |
Suppression of the GnRH pulse generator by neurokinin B involves a κ-opioid receptor-dependent mechanism.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Estradiol; Estrous Cycle; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Peptide Fragments; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Substance P | 2012 |
Central administration of neurokinin B activates kisspeptin/NKB neurons in the arcuate nucleus and stimulates luteinizing hormone secretion in ewes during the non-breeding season.
Topics: Anestrus; Animals; Arcuate Nucleus of Hypothalamus; Female; Kisspeptins; Luteinizing Hormone; Neurokinin B; Proto-Oncogene Proteins c-fos; Sheep | 2012 |
KNDy (kisspeptin/neurokinin B/dynorphin) neurons are activated during both pulsatile and surge secretion of LH in the ewe.
Topics: Animals; Dynorphins; Estrous Cycle; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Pituitary Gland, Anterior; Proto-Oncogene Proteins c-fos; Sheep | 2012 |
Differential modulation of gonadotropin responses to kisspeptin by aminoacidergic, peptidergic, and nitric oxide neurotransmission.
Topics: Animals; Dyneins; Follicle Stimulating Hormone; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamic Hormones; Kisspeptins; Luteinizing Hormone; Male; Melanins; Neurokinin B; Nitric Oxide; Pituitary Hormones; Rats; Rats, Wistar; Signal Transduction; Synaptic Transmission | 2012 |
Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man.
Topics: Adult; Aged; Aging; Arcuate Nucleus of Hypothalamus; Axons; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Male; Middle Aged; Neurokinin B; Neurons; Signal Transduction; Testosterone | 2012 |
GPR54-dependent stimulation of luteinizing hormone secretion by neurokinin B in prepubertal rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Bodily Secretions; Female; Kisspeptins; Luteinizing Hormone; Male; Naltrexone; Narcotic Antagonists; Neurokinin B; Peptide Fragments; Radioimmunoassay; Rats; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Tachykinin; Substance P | 2012 |
Molecular profiling of postnatal development of the hypothalamus in female and male rats.
Topics: Animals; Animals, Newborn; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Hypothalamus; Hypothalamus, Middle; Kisspeptins; Male; Nerve Tissue Proteins; Neurogenesis; Neurokinin B; Neurons; Preoptic Area; Progesterone; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sexual Maturation; Testosterone | 2012 |
Electrophysiological and morphological evidence for synchronized GnRH pulse generator activity among Kisspeptin/neurokinin B/dynorphin A (KNDy) neurons in goats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Axons; Dynorphins; Electrodes; Electrophysiological Phenomena; Female; Gene Expression Regulation, Developmental; Goats; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Neurokinin B; Neurons; Peptide Fragments; Pheromones; Substance P | 2013 |
Role for kisspeptin/neurokinin B/dynorphin (KNDy) neurons in cutaneous vasodilatation and the estrogen modulation of body temperature.
Topics: Animals; Body Temperature Regulation; Female; Kisspeptins; Neurokinin B; Neurons; Rats; Rats, Sprague-Dawley; Skin; Tail; Vasodilation | 2012 |
dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cerebral Ventricles; Dynorphins; Estrogens; Feedback, Physiological; Female; Gene Expression Regulation, Developmental; In Situ Hybridization; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Ovariectomy; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Opioid, kappa; RNA, Messenger; Signal Transduction; Tachykinins | 2013 |
Interactions between kisspeptins and neurokinin B.
Topics: Animals; Dynorphins; gamma-Aminobutyric Acid; Glutamic Acid; Gonadal Steroid Hormones; Humans; Kisspeptins; Luteinizing Hormone; Mutation; Neurokinin B; Neurons; Peptide Fragments; Puberty; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Rodentia; Sexual Maturation; Substance P | 2013 |
Neurokinin B activates arcuate kisspeptin neurons through multiple tachykinin receptors in the male mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Green Fluorescent Proteins; Kisspeptins; Male; Membrane Potentials; Mice; Mice, Transgenic; Neurokinin B; Neurons; Oligopeptides; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Quinolines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Receptors, Tachykinin; Substance P | 2013 |
Regulation of arcuate neurons coexpressing kisspeptin, neurokinin B, and dynorphin by modulators of neurokinin 3 and κ-opioid receptors in adult male mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Benzeneacetamides; Dynorphins; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Kisspeptins; Male; Membrane Potentials; Mice; Mice, Transgenic; Neurokinin B; Neurons; Orchiectomy; Peptide Fragments; Pyrrolidines; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Substance P; Time Factors | 2013 |
Kisspeptin, neurokinin B, and dynorphin act in the arcuate nucleus to control activity of the GnRH pulse generator in ewes.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; N-Methylaspartate; Neurokinin B; Neurons; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Sheep | 2013 |
Substance P immunoreactivity exhibits frequent colocalization with kisspeptin and neurokinin B in the human infundibular region.
Topics: Adult; Aged; Aged, 80 and over; Arcuate Nucleus of Hypothalamus; Axons; Capillaries; Cell Body; Female; Fluorescent Antibody Technique; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Male; Middle Aged; Neurokinin B; Pituitary Gland; Protein Transport; Substance P; Young Adult | 2013 |
A population of kisspeptin/neurokinin B neurons in the arcuate nucleus may be the central target of the male effect phenomenon in goats.
Topics: Amygdala; Animals; Arcuate Nucleus of Hypothalamus; Electrodes, Implanted; Female; Gene Expression Regulation; Goats; Gonadotropin-Releasing Hormone; Injections, Intraventricular; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Neurons; Ovariectomy; Pheromones; Quinolines; Receptors, Neurokinin-3; Reproduction; Signal Transduction | 2013 |
New developments in kisspeptin, neurokinin B and dynorphin A regulation of gonadotropin-releasing hormone pulsatile secretion.
Topics: Animals; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Rats; Sheep; Signal Transduction | 2014 |
Neurokinin B- and kisspeptin-positive fibers as well as tuberoinfundibular dopaminergic neurons directly innervate periventricular hypophyseal dopaminergic neurons in rats and mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dopaminergic Neurons; Female; Hypothalamic Area, Lateral; Imaging, Three-Dimensional; Kisspeptins; Mice; Mice, Inbred BALB C; Nerve Fibers; Neuroimaging; Neurokinin B; Rats; Rats, Wistar; Receptors, Neurokinin-3; Stilbamidines; Tyrosine 3-Monooxygenase | 2014 |
Prenatal androgen excess enhances stimulation of the GNRH pulse in pubertal female rats.
Topics: Androgens; Animals; Dihydrotestosterone; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Leptin; Luteinizing Hormone; Male; Models, Animal; Neurokinin B; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sexual Maturation | 2014 |
Photoperiodic co-regulation of kisseptin, neurokinin B and dynorphin in the hypothalamus of a seasonal rodent.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cricetinae; Dorsomedial Hypothalamic Nucleus; Dynorphins; Gene Expression Regulation; Kisspeptins; Male; Mesocricetus; Neurokinin B; Neurons; Neuropeptides; Photoperiod; Seasons | 2014 |
Disparate changes in kisspeptin and neurokinin B expression in the arcuate nucleus after sex steroid manipulation reveal differential regulation of the two KNDy peptides in rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Castration; Cell Count; Dynorphins; Female; Gonadal Steroid Hormones; Kisspeptins; Male; Neurokinin B; Neurons; Rats; Rats, Wistar; Sex Characteristics | 2014 |
Colocalization of cocaine- and amphetamine-regulated transcript with kisspeptin and neurokinin B in the human infundibular region.
Topics: Aged; Aged, 80 and over; Agouti-Related Protein; Axons; Female; Fluorescent Antibody Technique; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Middle Aged; Nerve Tissue Proteins; Neurokinin B; Pituitary Gland; Protein Transport; Substance P | 2014 |
Hypophysiotropic gonadotropin-releasing hormone projections are exposed to dense plexuses of kisspeptin, neurokinin B and substance p immunoreactive fibers in the human: a study on tissues from postmenopausal women.
Topics: Aged; Aged, 80 and over; Axons; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Immunohistochemistry; Kisspeptins; Middle Aged; Neurokinin B; Neurons; Pituitary Gland; Postmenopause; Substance P | 2014 |
Analysis of the serum concentrations of kisspeptin and neurokinin B in the geese during reproductive cycle and their localisation in the ovary.
Topics: Animals; Anseriformes; Female; Kisspeptins; Neurokinin B; Ovary; Protein Transport; Reproduction | 2014 |
Expression of neurokinin B/NK3 receptor and kisspeptin/KISS1 receptor in human granulosa cells.
Topics: Cells, Cultured; Female; Granulosa Cells; Humans; Kisspeptins; Neurokinin B; Receptors, Tachykinin; RNA, Messenger | 2014 |
Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats.
Topics: Aging; Animals; Dynorphins; Enkephalins; Female; Follicle Stimulating Hormone; Hypothalamus; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Peptide Fragments; Protein Precursors; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 2015 |
Prenatal testosterone excess decreases neurokinin 3 receptor immunoreactivity within the arcuate nucleus KNDy cell population.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Fetus; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Pregnancy; Receptors, Neurokinin-3; Sheep; Testosterone | 2015 |
Significance of serum neurokinin B and kisspeptin levels in the differential diagnosis of premature thelarche and idiopathic central precocious puberty.
Topics: Biomarkers; Child; Child, Preschool; Diagnosis, Differential; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kisspeptins; Leptin; Neurokinin B; Puberty, Precocious | 2015 |
Chronic oestradiol reduces the dendritic spine density of KNDy (kisspeptin/neurokinin B/dynorphin) neurones in the arcuate nucleus of ovariectomised Tac2-enhanced green fluorescent protein transgenic mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dendritic Spines; Down-Regulation; Dynorphins; Estradiol; Female; Green Fluorescent Proteins; Kisspeptins; Male; Mice; Mice, Transgenic; Neurokinin B; Neurons; Ovariectomy; Pregnancy; Protein Precursors; Tachykinins; Time Factors; Transgenes | 2015 |
Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Immunohistochemistry; In Situ Hybridization; Kisspeptins; Luteinizing Hormone; Models, Animal; Neurokinin B; Neurons; Neurotransmitter Agents; Ovariectomy; Peptide Fragments; Receptors, Neurokinin-3; RNA, Messenger; Sheep; Substance P | 2015 |
Evidence for Changes in Numbers of Synaptic Inputs onto KNDy and GnRH Neurones during the Preovulatory LH Surge in the Ewe.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Ovulation; Preoptic Area; Sheep; Vesicular Glutamate Transport Protein 2 | 2015 |
Prenatal Testosterone Treatment Leads to Changes in the Morphology of KNDy Neurons, Their Inputs, and Projections to GnRH Cells in Female Sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Disease Models, Animal; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neurons; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Preoptic Area; Sheep; Testosterone | 2015 |
Does salt have a permissive role in the induction of puberty?
Topics: Age Factors; Animals; Arcuate Nucleus of Hypothalamus; Body Mass Index; Child; Diet; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Male; Mice; Neurokinin B; Neurons; Obesity; Puberty; Rats; Reproduction; Sexual Maturation; Sodium Chloride, Dietary | 2015 |
Regulation of kisspeptin and gonadotropin-releasing hormone expression in rat placenta: study using primary cultures of rat placental cells.
Topics: Animals; Cells, Cultured; Estradiol; Female; Gene Expression Regulation, Developmental; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Placenta; Pregnancy; Rats | 2015 |
KNDy Neurons Modulate the Magnitude of the Steroid-Induced Luteinizing Hormone Surges in Ovariectomized Rats.
Topics: Animals; Dynorphins; Female; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Ovariectomy; Pituitary Gland; Rats; Rats, Wistar | 2015 |
Both Estrogen and Androgen Modify the Response to Activation of Neurokinin-3 and κ-Opioid Receptors in Arcuate Kisspeptin Neurons From Male Mice.
Topics: Androgens; Animals; Arcuate Nucleus of Hypothalamus; Dihydrotestosterone; Dynorphins; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Neurokinin B; Neurons; Orchiectomy; Patch-Clamp Techniques; Peptide Fragments; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Receptors, Steroid; Substance P | 2016 |
A Direct Neurokinin B Projection from the Arcuate Nucleus Regulates Magnocellular Vasopressin Cells of the Supraoptic Nucleus.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Infusions, Intraventricular; Kisspeptins; Male; Mice; Mice, Transgenic; Neuroanatomical Tract-Tracing Techniques; Neurokinin B; Neurons; Oxytocin; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Receptors, Neurokinin-3; Substance P; Supraoptic Nucleus; Vasopressins | 2016 |
Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression.
Topics: Animals; Blotting, Western; Chromatin Immunoprecipitation; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Follicle Stimulating Hormone; GATA Transcription Factors; Gene Expression Regulation, Developmental; Gonadotropin-Releasing Hormone; Gonadotropins; Histone Demethylases; Hypothalamus; In Situ Hybridization, Fluorescence; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Neurokinin B; Puberty; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Zinc Fingers | 2015 |
Immunoelectron microscopic observation of the subcellular localization of kisspeptin, neurokinin B and dynorphin A in KNDy neurons in the arcuate nucleus of the female rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Kisspeptins; Microscopy, Immunoelectron; Neurokinin B; Neurons; Rats, Wistar | 2016 |
Identifying late-onset fetal growth restriction by measuring circulating placental RNA in the maternal blood at 28 weeks' gestation.
Topics: Activating Transcription Factor 3; Adrenomedullin; Adult; Biomarkers; Case-Control Studies; Cesarean Section; Cohort Studies; DNA-Binding Proteins; Female; Fetal Growth Retardation; Gene Products, env; Gestational Age; Hospitalization; Humans; Infant, Newborn; Kisspeptins; Microarray Analysis; Neurokinin B; Placental Circulation; Polymerase Chain Reaction; Pregnancy; Pregnancy Proteins; Pregnancy-Associated Plasma Protein-A; RNA, Messenger | 2016 |
Ablation of KNDy Neurons Results in Hypogonadotropic Hypogonadism and Amplifies the Steroid-Induced LH Surge in Female Rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dynorphins; Estradiol; Estrous Cycle; Female; Hypogonadism; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Progesterone; Rats; Rats, Sprague-Dawley | 2016 |
Immunohistochemical characterization of the arcuate kisspeptin/neurokinin B/dynorphin (KNDy) and preoptic kisspeptin neuronal populations in the hypothalamus during the estrous cycle in heifers.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Breeding; Cattle; Dynorphins; Estradiol; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Immunohistochemistry; Kisspeptins; Neurokinin B; Neurons; Preoptic Area; Progesterone; Radioimmunoassay | 2016 |
Investigating the KNDy Hypothesis in Humans by Coadministration of Kisspeptin, Neurokinin B, and Naltrexone in Men.
Topics: Adult; Drug Therapy, Combination; Gene Expression Regulation; Gonadotropins; Humans; Kisspeptins; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neurokinin B; Neurotransmitter Agents; Prospective Studies; Single-Blind Method | 2016 |
The interaction of fasting, caloric restriction, and diet-induced obesity with 17β-estradiol on the expression of KNDy neuropeptides and their receptors in the female mouse.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Composition; Body Weight; Caloric Restriction; Diet; Diet, High-Fat; Dynorphins; Estradiol; Fasting; Female; Gene Expression Profiling; Gene Expression Regulation; Ghrelin; Kisspeptins; Mice, Inbred C57BL; Models, Biological; Neurokinin B; Neurons; Neuropeptides; Obesity; Organ Size; Signal Transduction | 2016 |
Prenatal testosterone exposure decreases colocalization of insulin receptors in kisspeptin/neurokinin B/dynorphin and agouti-related peptide neurons of the adult ewe.
Topics: Aging; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Receptor, Insulin; Sheep; Testosterone | 2016 |
High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Electrophysiological Phenomena; Gonadotropin-Releasing Hormone; Kisspeptins; Mice; Neurokinin B; Neurons; Optogenetics; Real-Time Polymerase Chain Reaction | 2016 |
A kiss to set the rhythm.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Channelrhodopsins; Dynorphins; Excitatory Postsynaptic Potentials; Female; Fertility; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Kisspeptins; Light; Male; Mice; Neurokinin B; Neurons; Optogenetics; Ovary; Periodicity; Pituitary Gland; Reproduction; Signal Transduction; Testis | 2016 |
Do Substance P and Neurokinin A Play Important Roles in the Control of LH Secretion in Ewes?
Topics: Animals; Dose-Response Relationship, Drug; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Immunohistochemistry; Kisspeptins; Luteinizing Hormone; Neurokinin A; Neurokinin B; Neurons; Receptors, Neurokinin-1; Sheep; Signal Transduction; Substance P | 2016 |
Age-related alterations in hypothalamic kisspeptin, neurokinin B, and dynorphin neurons and in pulsatile LH release in female and male rats.
Topics: Aging; Animals; Dynorphins; Female; Histocytochemistry; Hypothalamus; Kisspeptins; Luteinizing Hormone; Male; Menopause; Neurokinin B; Neurons; Pulsatile Flow; Rats, Wistar | 2017 |
Engineering a gene silencing viral construct that targets the cat hypothalamus to induce permanent sterility: An update.
Topics: Animals; Cats; Contraception; Dependovirus; Gene Expression; Gene Silencing; Genetic Engineering; Genetic Vectors; Hypothalamus; Infertility; Kisspeptins; Neurokinin B; RNA Interference | 2017 |
Basal Serum Neurokinin B Levels in Differentiating Idiopathic Central Precocious Puberty from Premature Thelarche.
Topics: Breast; Child; Diagnosis, Differential; Female; Follicle Stimulating Hormone; Humans; Kisspeptins; Luteinizing Hormone; Neurokinin B; Puberty, Precocious; ROC Curve | 2017 |
Effects of Orchidectomy and Testosterone Replacement on Numbers of Kisspeptin-, Neurokinin B-, and Dynorphin A-Immunoreactive Neurones in the Arcuate Nucleus of the Hypothalamus in Obese and Diabetic Rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diabetes Mellitus, Experimental; Diet, High-Fat; Dynorphins; Kisspeptins; Male; Neurokinin B; Neurons; Obesity; Orchiectomy; Rats; Testosterone | 2017 |
Effects of Season and Estradiol on KNDy Neuron Peptides, Colocalization With D2 Dopamine Receptors, and Dopaminergic Inputs in the Ewe.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dopaminergic Neurons; Dynorphins; Estradiol; Female; Kisspeptins; Neurokinin B; Neurons; Ovariectomy; Receptors, Dopamine D2; Reproduction; Seasons; Sheep | 2017 |
Effect of androgen on
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dihydrotestosterone; Drug Administration Schedule; Female; Gene Expression Regulation; Genes, fos; Hypothalamus, Anterior; Immunohistochemistry; Kisspeptins; Luteinizing Hormone; Neurokinin B; Rats; Receptors, Androgen; RNA, Messenger | 2017 |
Neurokinin 3 Receptor Antagonism Reveals Roles for Neurokinin B in the Regulation of Gonadotropin Secretion and Hot Flashes in Postmenopausal Women.
Topics: Administration, Oral; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Hot Flashes; Humans; Kisspeptins; Luteinizing Hormone; Middle Aged; Neurokinin B; Periodicity; Postmenopause; Receptors, Neurokinin-3; Treatment Outcome | 2018 |
Evidence of involvement of neurone-glia/neurone-neurone communications via gap junctions in synchronised activity of KNDy neurones.
Topics: Animals; Cells, Cultured; Connexins; Dynorphins; Gap Junctions; Glycyrrhetinic Acid; Kisspeptins; Medulla Oblongata; Mefloquine; Mice, Transgenic; Neuroglia; Neurokinin B; Neurons; Peptide Fragments; Substance P | 2017 |
KNDy neurone activation prior to the LH surge of the ewe is disrupted by LPS.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Crosses, Genetic; Dynorphins; Female; Fluorescent Antibody Technique; Follicular Phase; Gonadotropin-Releasing Hormone; Immunohistochemistry; Injections, Intravenous; Kisspeptins; Lipopolysaccharides; Luteinizing Hormone; Nerve Tissue Proteins; Neurokinin B; Neurons; Ovary; Ovulation; Pituitary Gland; Sheep, Domestic | 2017 |
Oxytocin Intranasal Administration Affects Neural Networks Upstream of GNRH Neurons.
Topics: Administration, Intranasal; Animals; Gonadotropin-Releasing Hormone; Hippocampus; Kisspeptins; Male; Nerve Net; Neurokinin B; Neurons; Oxytocin; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2017 |
Neurokinin 3 receptor antagonism decreases gonadotropin and testosterone secretion in healthy men.
Topics: Adult; Follicle Stimulating Hormone; Gonadotropins; Heterocyclic Compounds, 2-Ring; Humans; Hypogonadism; Kisspeptins; Luteinizing Hormone; Male; Mutation; Neurokinin B; Receptors, Neurokinin-3; Testosterone; Thiadiazoles; Young Adult | 2017 |
Long-Term Recordings of Arcuate Nucleus Kisspeptin Neurons Reveal Patterned Activity That Is Modulated by Gonadal Steroids in Male Mice.
Topics: Action Potentials; Androgens; Animals; Arcuate Nucleus of Hypothalamus; Brain; Cluster Analysis; Dihydrotestosterone; Dynorphins; Estradiol; Estrogens; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Kisspeptins; Male; Mice; Mice, Transgenic; Neurokinin B; Neurons; Orchiectomy; Patch-Clamp Techniques; Receptors, Neurokinin-3 | 2017 |
Kisspeptin and Neurokinin B Signaling Network Underlies the Pubertal Increase in GnRH Release in Female Rhesus Monkeys.
Topics: Animals; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Macaca mulatta; Median Eminence; Neurokinin B; Neurons; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Sexual Maturation; Signal Transduction; Substance P | 2017 |
Distinct dynorphin expression patterns with low- and high-dose estrogen treatment in the arcuate nucleus of female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estradiol; Female; Gene Expression Regulation; Immunohistochemistry; In Situ Hybridization; Kisspeptins; Neurokinin B; Neurons; Ovariectomy; Rats; RNA, Messenger | 2017 |
Continuous Kisspeptin Restores Luteinizing Hormone Pulsatility Following Cessation by a Neurokinin B Antagonist in Female Sheep.
Topics: Animals; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Sheep | 2018 |
The effects of chronic testosterone administration on hypothalamic gonadotropin-releasing hormone regulatory factors (Kiss1, NKB, pDyn and RFRP) and their receptors in female rats.
Topics: Animals; Dynorphins; Estradiol; Female; Hypothalamus; Kisspeptins; Leptin; Luteinizing Hormone; Neurokinin B; Neurons; Rats; Rats, Wistar; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Testosterone | 2018 |
Expression of hypothalamic kisspeptin, neurokinin B, and dynorphin A neurons attenuates in female Zucker fatty rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Rats; Rats, Zucker | 2018 |
The usefulness of circulating levels of leptin, kisspeptin, and neurokinin B in obese girls with precocious puberty.
Topics: Biomarkers; Body Mass Index; Case-Control Studies; Child; Female; Humans; Kisspeptins; Leptin; Neurokinin B; Overweight; Pediatric Obesity; Predictive Value of Tests; Puberty, Precocious; Sexual Maturation | 2018 |
Three-dimensional imaging of KNDy neurons in the mammalian brain using optical tissue clearing and multiple-label immunocytochemistry.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Imaging, Three-Dimensional; Immunohistochemistry; Kisspeptins; Neurokinin B; Rats; Rats, Sprague-Dawley; Sheep | 2018 |
Role of Kisspeptin and Neurokinin B Signaling in Male Rhesus Monkey Puberty.
Topics: Animals; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Microdialysis; Neurokinin B; Neurons; Organ Size; Puberty; Signal Transduction; Testis; Testosterone | 2018 |
Evidence That Dynorphin Acts Upon KNDy and GnRH Neurons During GnRH Pulse Termination in the Ewe.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Receptors, Opioid, kappa; Sheep | 2018 |
Energy balance affects pulsatile secretion of luteinizing hormone from the adenohypophesis and expression of neurokinin B in the hypothalamus of ovariectomized gilts.
Topics: Animals; Energy Metabolism; Fatty Acids, Nonesterified; Female; Follicle Stimulating Hormone; Food Deprivation; Hypothalamus; Insulin; Kisspeptins; Leptin; Luteinizing Hormone; Neurokinin B; Neurons; Pituitary Gland, Anterior; Receptors, LHRH; Swine | 2018 |
Various responses of male pituitary-gonadal axis to different intensities of long-term exercise: Role of expression of KNDYrelated genes.
Topics: Animals; Enkephalins; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Gonads; Humans; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Neurons; Physical Conditioning, Animal; Pituitary Gland; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Testosterone | 2018 |
Central Orexin A Affects Reproductive Axis by Modulation of Hypothalamic Kisspeptin/Neurokinin B/Dynorphin Secreting Neurons in the Male Wistar Rats.
Topics: Animals; Benzoxazoles; Dioxanes; Dynorphins; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Hypothalamus; Injections, Intraventricular; Kisspeptins; Luteinizing Hormone; Male; Naphthyridines; Neurokinin B; Neurons; Orexins; Phenylurea Compounds; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reproduction; Sexual Behavior, Animal; Testosterone; Urea | 2018 |
The effect of diet control on puberty onset and immunoreactivity of kisspeptin and neurokinin B in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diet, High-Fat; Female; Kisspeptins; Neurokinin B; Neurons; Rats; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Sexual Maturation; Signal Transduction | 2018 |
High-fat diet and type 2 diabetes induced disruption of the oestrous cycle and alteration of hormonal profiles, but did not affect subpopulations of KNDy neurones in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diabetes Mellitus, Type 2; Diet, High-Fat; Dynorphins; Estrous Cycle; Female; Insulin; Kisspeptins; Leptin; Neurokinin B; Neurons; Neuropeptides; Peptide Hormones; Rats, Wistar | 2018 |
Altered expression of the kisspeptin/KISS1R and neurokinin B/NK3R systems in mural granulosa and cumulus cells of patients with polycystic ovarian syndrome.
Topics: Adult; Case-Control Studies; Cells, Cultured; Cross-Sectional Studies; Cumulus Cells; Female; Gene Expression Regulation; Granulosa Cells; Humans; Kisspeptins; Neurokinin B; Polycystic Ovary Syndrome; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Young Adult | 2019 |
Sex- and sub region-dependent modulation of arcuate kisspeptin neurones by vasopressin and vasoactive intestinal peptide.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Calcium; Female; Kisspeptins; Male; Mice; Mice, Transgenic; Neurokinin B; Neurons; Sex Characteristics; Vasoactive Intestinal Peptide; Vasopressins | 2018 |
NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Corticomedial Nuclear Complex; Estrogens; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Mice; Mice, Knockout; Neurokinin B; Neurons; Receptors, Tachykinin; Signal Transduction | 2018 |
Glutamatergic Neurokinin 3 Receptor Neurons in the Median Preoptic Nucleus Modulate Heat-Defense Pathways in Female Mice.
Topics: Animals; Body Temperature Regulation; Dynorphins; Female; Glutamic Acid; Hot Flashes; Hot Temperature; Kisspeptins; Mice; Neurokinin B; Neurons; Preoptic Area; Proto-Oncogene Proteins c-fos; Receptors, Neurokinin-3 | 2019 |
Neonatal Estrogen Causes Irreversible Male Infertility via Specific Suppressive Action on Hypothalamic Kiss1 Neurons.
Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; Dynorphins; Estradiol; Gene Expression Regulation, Developmental; In Situ Hybridization; Infertility, Male; Kisspeptins; Male; Neurokinin B; Neurons; Rats, Wistar; Spermatogenesis; Testosterone | 2019 |
Hypothalamic Reproductive Endocrine Pulse Generator Activity Independent of Neurokinin B and Dynorphin Signaling.
Topics: Academic Medical Centers; Adolescent; Adult; Animals; Case-Control Studies; Child; Disease Models, Animal; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Kisspeptins; Luteinizing Hormone; Mice; Mice, Knockout; Narcotic Antagonists; Neurokinin B; Neurons; Signal Transduction; Substance P; Treatment Outcome; Young Adult | 2019 |
Ad libitum feeding triggers puberty onset associated with increases in arcuate Kiss1 and Pdyn expression in growth-retarded rats.
Topics: Animal Feed; Animals; Arcuate Nucleus of Hypothalamus; Brain; Enkephalins; Female; Food Deprivation; Growth Disorders; Hypothalamus, Anterior; Kisspeptins; Luteinizing Hormone; Neurokinin B; Ovarian Follicle; Ovary; Protein Precursors; Rats; Rats, Wistar; Sexual Maturation; Uterus | 2019 |
Prenatal Testosterone Exposure Alters GABAergic Synaptic Inputs to GnRH and KNDy Neurons in a Sheep Model of Polycystic Ovarian Syndrome.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Disease Models, Animal; Dynorphins; Female; GABAergic Neurons; Gonadotropin-Releasing Hormone; K Cl- Cotransporters; Kisspeptins; Neurokinin B; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Preoptic Area; Sheep; Solute Carrier Family 12, Member 2; Symporters; Testosterone | 2019 |
Characterization of the Role of NKA in the Control of Puberty Onset and Gonadotropin Release in the Female Mouse.
Topics: Animals; Female; Gonadotropins; Kisspeptins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin A; Neurokinin B; Protein Precursors; Receptors, Neurokinin-2; Sexual Maturation; Substance P; Tachykinins | 2019 |
Evidence That the LH Surge in Ewes Involves Both Neurokinin B-Dependent and -Independent Actions of Kisspeptin.
Topics: Animals; Female; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Sheep | 2019 |
Kisspeptin/Neurokinin B/Dynorphin (KNDy) cells as integrators of diverse internal and external cues: evidence from viral-based monosynaptic tract-tracing in mice.
Topics: Animals; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Male; Mice; Neurokinin B; Neurons; Reproduction; Sex Characteristics | 2019 |
The Origin of GnRH Pulse Generation: An Integrative Mathematical-Experimental Approach.
Topics: Animals; Dynorphins; Estrous Cycle; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Theoretical; Neurokinin B; Neurons; Optogenetics; Pregnancy; Reproduction; Ultradian Rhythm | 2019 |
Sexually dimorphic gene expression and neurite sensitivity to estradiol in fetal arcuate Kiss1 cells.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Estradiol; Female; Gene Expression Regulation, Developmental; Kisspeptins; Male; Mice; Mice, Inbred C57BL; Neurites; Neurokinin B; Sex Characteristics | 2020 |
Kisspeptin, Neurokinin B and New Players in Reproduction.
Topics: Animals; Humans; Kisspeptins; Neurokinin B; Reproduction | 2019 |
Kisspeptin, Neurokinin B and New Players in Reproduction.
Topics: Animals; Female; History, 20th Century; History, 21st Century; Humans; Hypothalamus; Kisspeptins; Neurokinin B; Puberty; Reproduction; Reproductive Techniques, Assisted | 2019 |
Kisspeptin, Neurokinin B and New Players in Reproduction.
Topics: Animals; Humans; Kisspeptins; Neurokinin B; Reproduction; Review Literature as Topic; Signal Transduction | 2019 |
Role for Kisspeptin and Neurokinin B in Regulation of Luteinizing Hormone and Testosterone Secretion in the Fetal Sheep.
Topics: Animals; Female; Fetus; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Oligopeptides; Peptide Fragments; Pregnancy; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Sheep; Substance P; Testosterone | 2020 |
Hyperactive LH Pulses and Elevated Kisspeptin and NKB Gene Expression in the Arcuate Nucleus of a PCOS Mouse Model.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aromatase Inhibitors; Disease Models, Animal; Dynorphins; Female; Gene Expression; Kisspeptins; Letrozole; Luteinizing Hormone; Mice; Neurokinin B; Neurons; Polycystic Ovary Syndrome | 2020 |
Expression of genes for Kisspeptin (KISS1), Neurokinin B (TAC3), Prodynorphin (PDYN), and gonadotropin inhibitory hormone (RFRP) across natural puberty in ewes.
Topics: Animals; Enkephalins; Female; Gene Expression; Hypothalamus; Kisspeptins; Neurokinin B; Neuropeptides; Protein Precursors; Receptors, Kisspeptin-1; Sheep, Domestic | 2020 |
Central injection of neuropeptide Y modulates sexual behavior in male rats: interaction with GnRH and kisspeptin/neurokinin B/dynorphin.
Topics: Animals; Dynorphins; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Male; Neurokinin B; Neuropeptide Y; Rats, Wistar; Sexual Behavior, Animal; Signal Transduction | 2021 |
Direct inhibition of arcuate kisspeptin neurones by neuropeptide Y in the male and female mouse.
Topics: Agouti-Related Protein; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Calcium; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Male; Mice; Neurokinin B; Neuropeptide Y | 2020 |
MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Female; Gene Expression Regulation; Gonadotropin-Releasing Hormone; HEK293 Cells; Humans; Kisspeptins; Male; Mice; Neurokinin B; Neurons; Promoter Regions, Genetic; Puberty, Precocious; Rats, Sprague-Dawley; Transcription, Genetic; Ubiquitin-Protein Ligases | 2020 |
Establishment of immortalised cell lines derived from female Shiba goat KNDy and GnRH neurones.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cell Line, Transformed; Dynorphins; Female; Goats; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neurons; Primary Cell Culture | 2020 |
Morphological and functional evidence for sexual dimorphism in neurokinin B signalling in the retrochiasmatic area of sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Female; Hypothalamus, Middle; Kisspeptins; Male; Neurokinin B; Neurons; Receptors, Tachykinin; Sex Characteristics; Sheep; Signal Transduction | 2020 |
A genetic association study of kisspeptin 1/ neurokinin B systems in patients with infertility: Is it that simple?
Topics: Cumulus Cells; Female; Genetic Association Studies; Humans; Infertility, Female; Kisspeptins; Neurokinin B | 2020 |
Effects of Ovariectomy and Sex Hormone Replacement on Numbers of Kisspeptin-, Neurokinin B- and Dynorphin A-immunoreactive Neurons in the Arcuate Nucleus of the Hypothalamus in Obese and Diabetic Rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diabetes Mellitus, Experimental; Dynorphins; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Neurokinin B; Neurons; Obesity; Ovariectomy; Rats | 2020 |
Commentary on "Pharmacodynamic Activity of the Novel Neurokinin-3 Receptor Antagonist SJX-653 in Healthy Men".
Topics: Hormone Antagonists; Humans; Kisspeptins; Male; Neurokinin B; Receptors, Neurokinin-3 | 2021 |
Effect of electroacupuncture on the kisspeptin system in a pubertal rat model of polycystic ovary syndrome.
Topics: Acupuncture Points; Animals; Dynorphins; Electroacupuncture; Estrous Cycle; Female; Follicle Stimulating Hormone; Humans; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Ovary; Polycystic Ovary Syndrome; Pregnancy; Puberty; Rats; Rats, Sprague-Dawley | 2021 |
Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aromatase; Dynorphins; Feedback, Physiological; Female; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Gonadotropin-Releasing Hormone; Gonadotropins; Integrases; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Organ Size; Organogenesis; Ovarian Follicle; Pituitary Gland; Rats; Receptors, LH; Receptors, LHRH; RNA, Messenger | 2021 |
The role of makorin ring finger protein-3, kisspeptin, and neurokinin B in the physiology of minipuberty.
Topics: Female; Humans; Hypothalamo-Hypophyseal System; Infant; Infant, Newborn; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Ovary; Prospective Studies; Testis; Ubiquitin-Protein Ligases | 2021 |
Effect of diet-induced obesity on kisspeptin-neurokinin B-dynorphin A neurons in the arcuate nucleus and luteinizing hormone secretion in sex hormone-primed male and female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diet, High-Fat; Dynorphins; Female; Gonadal Steroid Hormones; Hypogonadism; Kisspeptins; Luteinizing Hormone; Male; Metabolic Diseases; Neurokinin B; Neurons; Obesity; Rats; Rats, Wistar | 2021 |
Localization of kisspeptin, NKB, and NK3R in the hypothalamus of gilts treated with the progestin altrenogest.
Topics: Animals; Female; Gene Expression Profiling; Hypothalamus; Kisspeptins; Neurokinin B; Progestins; Receptors, Neurokinin-3; Sus scrofa; Trenbolone Acetate | 2021 |
Targeting Elevated GnRH Pulsatility to Treat Polycystic Ovary Syndrome.
Topics: Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Polycystic Ovary Syndrome | 2021 |
Prenatal Androgen Exposure Alters KNDy Neurons and Their Afferent Network in a Model of Polycystic Ovarian Syndrome.
Topics: Afferent Pathways; Androgens; Animals; Disease Models, Animal; Dynorphins; Female; Kisspeptins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurokinin B; Neurons; Neurons, Afferent; Neurosecretory Systems; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects | 2021 |
Local administration of Neurokinin B in the arcuate nucleus accelerates the neural activity of the GnRH pulse generator in goats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Goats; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B | 2021 |
Evidence that pubertal status impacts kisspeptin/neurokinin B/dynorphin neurons in the gilt†.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Kisspeptins; Neurokinin B; Neurons; Sexual Maturation; Sus scrofa | 2021 |
Distribution of kisspeptin system and its relation with gonadotropin-releasing hormone in the hypothalamus of the South American plains vizcacha, Lagostomus maximus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Male; Mammals; Neurokinin B; Pregnancy; South America | 2022 |
Hypothalamic KNDy neuron expression in streptozotocin-induced diabetic female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diabetes Mellitus, Experimental; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neurons; Rats | 2022 |
Gonadotropin-releasing hormone-secreting neuron development and function: an update.
Topics: Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons | 2022 |
In vivo imaging of the GnRH pulse generator reveals a temporal order of neuronal activation and synchronization during each pulse.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Neurokinin B; Neurons; Reproduction | 2022 |
Undernutrition reduces kisspeptin and neurokinin B expression in castrated male sheep.
Topics: Animals; Body Weight; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Male; Malnutrition; Neurokinin B; Receptors, Neurokinin-3; RNA, Messenger; Sheep | 2020 |
Serum kisspeptin, leptin, neuropeptide Y, and neurokinin B levels in adolescents with polycystic ovary syndrome.
Topics: Adolescent; Body Mass Index; Female; Humans; Kisspeptins; Leptin; Neurokinin B; Neuropeptide Y; Polycystic Ovary Syndrome | 2022 |
The impact of undernutrition on KNDy (kisspeptin/neurokinin B/dynorphin) neurons in female lambs.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Malnutrition; Neurokinin B; Neurons; RNA, Messenger; Sheep | 2022 |
Origins of the 'KNDy hypothesis' of GnRH pulse generation.
Topics: Arcuate Nucleus of Hypothalamus; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B | 2022 |
Hyperandrogenism induces proportional changes in the expression of Kiss-1, Tac2, and DynA in hypothalamic KNDy neurons.
Topics: Androgens; Animals; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hyperandrogenism; Hypothalamus; Kisspeptins; Mice; Neurokinin B; Neurons; Rats; Tachykinins; Testosterone | 2022 |
How does apelin affect LH levels? An investigation at the level of GnRH and KNDy neurons.
Topics: Animals; Apelin; Apelin Receptors; Arcuate Nucleus of Hypothalamus; Colforsin; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Male; Mice; Neurokinin B; Neurons; Rats; Steroids | 2022 |
Hypothalamic Overexpression of Makorin Ring Finger Protein 3 Results in Delayed Puberty in Female Mice.
Topics: Animals; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Male; Mice; Neurokinin B; Sexual Maturation; Ubiquitin-Protein Ligases | 2022 |
Prior aerobic physical training modulates neuropeptide expression and central thermoregulation after ovariectomy in the rat.
Topics: Animals; Body Temperature Regulation; Estradiol; Female; Humans; Kisspeptins; Neurokinin B; Norepinephrine; Ovariectomy; Rats; Tyrosine 3-Monooxygenase | 2022 |
Conditional Deletion of KOR (Oprk1) in Kisspeptin Cells Does Not Alter LH Pulses, Puberty, or Fertility in Mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Fertility; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Male; Mice; Neurokinin B; Receptors, Opioid, kappa; Sexual Maturation | 2022 |
Partial loss of arcuate kisspeptin neurons in female rats stimulates luteinizing hormone and decreases prolactin secretion induced by estradiol.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estradiol; Female; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Prolactin; Rats; Tyrosine 3-Monooxygenase | 2022 |
Sex-related differences in obesity - role of the kisspeptin-neurokinin B-dynorphin A (KNDy) neurons.
Topics: Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Neurons; Obesity | 2023 |
Short-term depletion of plasma estrogen affects hypothalamic kisspeptin-neurokinin B-dynorphin A neurons, gonadotrophs, and pulsatile luteinizing hormone secretion in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Female; Gonadotrophs; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Rats | 2023 |
GnRH Pulse Generation in Rodents: Time to Terminate the Role of Dynorphin?
Topics: Animals; Dynorphins; Fertility; Gonadotropin-Releasing Hormone; Kisspeptins; Mice; Neurokinin B; Rodentia; Sexual Maturation | 2023 |
Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Glutamates; Hormones; Kisspeptins; Male; Mammals; Mice; Neurokinin B; Neurons | 2023 |
Effects of electroacupuncture on the kisspeptin-gonadotropin-releasing hormone (GnRH) /luteinizing hormone (LH) neural circuit abnormalities and androgen receptor expression of kisspeptin/neurokinin B/dynorphin neurons in PCOS rats.
Topics: Androgens; Animals; Dynorphins; Electroacupuncture; Estrogen Receptor alpha; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Hyperandrogenism; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Kisspeptin-1; RNA, Messenger | 2023 |
Serum kisspeptin, neurokinin B and inhibin B levels can be used as alternative parameters to distinguish idiopathic CPP from premature thelarche in the early stages of puberty.
Topics: Anti-Mullerian Hormone; Child; Child, Preschool; Cross-Sectional Studies; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Puberty; Puberty, Precocious | 2023 |
Effect of a neurokinin 3 receptor-selective agonist administration on the embryos recovered from superovulated cows.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cattle; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Mammals; Neurokinin B; Receptors, Neurokinin-3 | 2023 |
Decreased neurokinin B as a risk factor of functional hypothalamic amenorrhea.
Topics: Amenorrhea; Estradiol; Female; Humans; Kisspeptins; Neurokinin B; Risk Factors | 2023 |
Continuous acceleration of neural activity of the GnRH pulse generator during chronic peripheral infusion of neurokinin 3 receptor agonist in goats.
Topics: Animals; Goats; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Receptors, Neurokinin-3 | 2023 |
Lesions of KNDy and Kiss1R Neurons in the Arcuate Nucleus Produce Different Effects on LH Pulse Patterns in Female Sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; gamma-Aminobutyric Acid; Glutamates; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Receptors, Kisspeptin-1; RNA, Messenger; Saporins; Sheep | 2023 |
Mechanism of Arcuate Kisspeptin Neuron Synchronization in Acute Brain Slices From Female Mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Brain; Dynorphins; Female; Glutamates; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Neurokinin B; Neurons | 2023 |
Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Rats | 2023 |