neurokinin b has been researched along with dynorphins in 120 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.83) | 18.2507 |
| 2000's | 7 (5.83) | 29.6817 |
| 2010's | 78 (65.00) | 24.3611 |
| 2020's | 34 (28.33) | 2.80 |
| Authors | Studies |
|---|---|
| Donaldson, LF; Hanley, MR; Haskell, CA | 1 |
| Furuta, T; Kaneko, T; Zhou, L | 2 |
| Amstalden, M; Foradori, CD; Goodman, RL; Lehman, MN | 1 |
| Ciofi, P; Lapirot, OC; Tramu, G | 1 |
| Caraty, A; Ciofi, P; Clarke, IJ; Coolen, LM; de Oliveira, CV; Goodman, RL; Iqbal, J; Jafarzadehshirazi, MR; Lehman, MN; Pereira, A; Smith, JT | 1 |
| Rance, NE | 1 |
| Chavkin, C; Clifton, DK; Gottsch, ML; Navarro, VM; Okamura, H; Steiner, RA | 1 |
| Cheng, G; Coolen, LM; Goodman, RL; Lehman, MN; Padmanabhan, V | 1 |
| Clifton, DK; Maeda, K; Mogi, K; Mori, Y; Murata, K; Nakada, T; Navarro, VM; Ohkura, S; Okamura, H; Steiner, RA; Tsukamura, H; Wakabayashi, Y | 1 |
| Kotan, LD; Topaloglu, AK; Yuksel, B | 1 |
| Coolen, LM; Goodman, RL; Lehman, MN | 2 |
| Mori, Y; Murata, K; Ohkura, S; Okamura, H; Sakamoto, K; Takeuchi, Y; Wakabayashi, Y | 1 |
| Cholanian, M; Dacks, PA; Krajewski, SJ; Rance, NE; Smith, MA | 1 |
| Maeda, K; Ohkura, S; Oka, Y; Okamura, H; Tsukamura, H; Uenoyama, Y; Wakabayashi, Y | 1 |
| Navarro, VM; Tena-Sempere, M | 1 |
| Alreja, M; Bosch, MA; Braun, RE; Clifton, DK; Dearth, A; García-Galiano, D; Gottsch, ML; Hobbs, SJ; Navarro, VM; Palmiter, RD; Pinilla, L; Ronnekleiv, OK; Steiner, RA; Tena-Sempere, M; Wu, M | 1 |
| Grachev, P; Kinsey-Jones, JS; Li, XF; Lightman, SL; Lin, YS; Milligan, SR; O'Byrne, KT | 1 |
| Ciofi, P; Krajewski-Hall, SJ; Lai, J; McMullen, NT; Mittelman-Smith, MA; Rance, NE; Williams, H | 1 |
| Kanasaki, H; Mijiddorj, T; Miyazaki, K; Oride, A; Purwana, IN; Sukhbaatar, U | 1 |
| Aguilar, E; Dieguez, C; Millar, RP; Pinilla, L; Tena-Sempere, M | 1 |
| Bloom, SR; Borsay, BÁ; Ciofi, P; Dhillo, WS; Gergely, P; Ghatei, MA; Herczeg, L; Hrabovszky, E; Liposits, Z; Molnár, CS; Sipos, MT | 1 |
| Billings, HJ; Coolen, LM; Drews, S; Goodman, RL; Hileman, SM; Lehman, MN; Merkley, CM; Porter, KL | 1 |
| Mori, Y; Okamura, H; Sakamoto, K; Wakabayashi, Y; Yamamura, T | 1 |
| Deura, C; Ieda, N; Maeda, K; Minabe, S; Mostari, P; Tsukamura, H; Uenoyama, Y; Yamada, S | 1 |
| Goodman, RL; Hileman, SM; Lehman, MN | 1 |
| Maeda, K; Ohkura, S; Okamura, H; Tsukamura, H; Uenoyama, Y; Wakabayashi, Y | 1 |
| Navarro, VM | 2 |
| Alreja, M | 1 |
| Boehm, U; de Croft, S; Herbison, AE | 1 |
| Burger, LL; Moenter, SM; Ruka, KA | 2 |
| Bedecarrats, GY; Joseph, NT; Millar, RP; Tello, JA | 1 |
| Dacks, PA; Krajewski-Hall, SJ; Mittelman-Smith, MA; Rance, NE; Romanovsky, AA | 1 |
| Deura, C; Fujii, N; Iwase, A; Kikkawa, F; Maeda, K; Minabe, S; Nakahara, T; Nakamura, S; Noguchi, T; Oishi, S; Tsukamura, H; Uenoyama, Y; Watanabe, Y | 1 |
| Cernea, M; Connors, JM; Coolen, LM; Goodman, RL; Hardy, SL; Hileman, SM; Lehman, MN; Millar, RP; Nestor, CC; Porter, KL | 1 |
| Grachev, P; Millar, RP; O'Byrne, KT | 1 |
| Millar, RP | 1 |
| Maeda, K; Tsukamura, H; Uenoyama, Y | 1 |
| Bartzen-Sprauer, J; Ciofi, P; Klosen, P; Mikkelsen, JD; Simonneaux, V | 1 |
| Castellano, JM; Mikkelsen, JD; Overgaard, A; Ruiz-Pino, F; Tena-Sempere, M | 1 |
| He, M; Hu, G; Lin, C; Wong, AO | 1 |
| Garcia-Galiano, D; Leon, S; Manfredi-Lozano, M; Navarro, VM; Pinilla, L; Roa, J; Ruiz-Pino, F; Sánchez-Garrido, MA; Tena-Sempere, M | 1 |
| Ahn, T; Coolen, LM; Fergani, C; Lehman, MN; Padmanabhan, V | 1 |
| Cholanian, M; Krajewski-Hall, SJ; McMullen, NT; Rance, NE | 1 |
| Clarke, IJ; Li, Q; Millar, RP; Smith, JT | 1 |
| Coolen, LM; Goodman, RL; Lehman, MN; Merkley, CM | 1 |
| Chavkin, C; Clifton, DK; Ferrara, LK; Oakley, AE; Reed, SD; Steiner, RA | 1 |
| Cernea, M; Coolen, LM; Goodman, RL; Lehman, MN; Padmanabhan, V | 1 |
| Flynn, FW; Pitynski, D; Skinner, DC | 1 |
| Anselmo-Franci, JA; Bertram, R; Carolino, RO; Helena, CV; Kalil, B; Pogrebna, VV; Stathopoulos, AM; Toporikova, N | 1 |
| Iwata, K; Murakawa, H; Ozawa, H; Takeshita, T | 1 |
| Krajewski-Hall, SJ; McMullen, NT; Mittelman-Smith, MA; Rance, NE | 1 |
| Hassaneen, A; Ieda, N; Inoue, N; Kimura, K; Maeda, KI; Matsuda, F; Matsuyama, S; Naniwa, Y; Ohkura, S; Suetomi, Y; Tsukamura, H; Uenoyama, Y | 1 |
| Chrousos, GP; Livadas, S | 1 |
| Roepke, TA; Snyder, M; Yang, JA; Yasrebi, A | 1 |
| Cernea, M; Coolen, LM; Lehman, MN; Padmanabhan, V; Phillips, R | 1 |
| Prevot, V; Shruti, S | 1 |
| Ishigami, A; Iwata, K; Kunimura, Y; Ozawa, H | 1 |
| Dudek, M; Kołodziejski, PA; Pruszyńska-Oszmałek, E; Sliwowska, JH; Ziarniak, K | 1 |
| Clarke, IJ; Coolen, LM; Goodman, RL; Lehman, MN; Smith, J; Weems, P | 1 |
| Goto, T; Hirabayashi, M; Ieda, N; Ikegami, K; Inoue, N; Maeda, KI; Maturana, AD; Minabe, S; Nakamura, S; Oishi, S; Sanbo, M; Sugimoto, A; Tsukamura, H; Uenoyama, Y | 1 |
| Dobson, H; Fergani, C; Jones, DN; Pickavance, LC; Routly, JE; Smith, RF | 1 |
| DeFazio, RA; Johnson, ML; Moenter, SM; Moya, MR; Vanacker, C | 1 |
| Iwata, K; Kanaya, M; Ozawa, H | 1 |
| Irahara, M; Iwasa, T; Matsuzaki, T; Mayila, Y; Yanagihara, R; Yano, K | 1 |
| Iwata, K; Nakao, K; Ozawa, H; Takeshita, T | 1 |
| Coolen, LM; Goodman, RL; Lehman, MN; Lucas, KA; Moore, AM | 1 |
| Bedenbaugh, MN; Coolen, LM; Goodman, RL; Hileman, SM; Lehman, MN; Nestor, CC | 1 |
| Czyzyk, A; Genazzani, AD; Genazzani, AR; Meczekalski, B; Podfigurna, A; Szeliga, A | 1 |
| Khoradmehr, A; Mohammad Reza, JS; Saedi, S; Tamadon, A | 1 |
| Coolen, LM; Goodman, RL; Lehman, MN; Moore, AM; Porter, DT | 1 |
| Coolen, LM; Goodman, RL; Hardy, S; Hileman, SM; Lehman, MN; McCosh, RB; Weems, PW | 1 |
| Hosseini, A; Khazali, H | 1 |
| Kallό, I; Kołodziejski, PA; Pruszyńska-Oszmałek, E; Śliwowska, JH; Ziarniak, K | 1 |
| Blackmore, EM; Krajewski-Hall, SJ; McMullen, NT; Miranda Dos Santos, F; Rance, NE | 1 |
| Inoue, N; Magata, F; Matsuda, F; Minabe, S; Ozawa, H; Sato, M; Tsukamura, H; Uenoyama, Y; Watanabe, Y | 1 |
| Arlt, W; Chan, YM; Cole, TR; Farooqi, IS; Fergani, C; Hall, JE; Jones, CM; León, S; Lippincott, MF; Navarro, VM; Seminara, SB; Shaw, ND; Stewart, SE; Talbi, R; Terasawa, E | 1 |
| Plant, TM | 1 |
| Cobern, JA; Coolen, LM; Goodman, RL; Lehman, MN; Moore, AM; Padmanabhan, V; Porter, DT | 1 |
| Coolen, LM; Lehman, MN; Moore, AM | 2 |
| De Burgh, R; Lass, G; Li, XF; Lightman, SL; O'Byrne, KT; Tsaneva-Atanasova, K; Voliotis, M | 1 |
| Bennett, N; Voigt, C | 1 |
| Dees, WL; Hiney, JK; Srivastava, VK | 1 |
| Coolen, LM; Goodman, RL; He, W; Lehman, MN; Levine, JE | 1 |
| Esparza, LA; Ho, BS; Kauffman, AS; Schafer, D; Thackray, VG | 1 |
| Azizi, V; Hosseini, A; Khazali, H; Oryan, S | 1 |
| Inoue, N; Matsuda, F; Matsuyama, S; Munetomo, A; Ohkura, S; Sonoda, S; Suetomi, Y; Takeuchi, Y; Tatebayashi, R; Tsukamura, H; Uenoyama, Y | 1 |
| Dudek, M; Kalló, I; Kołodziejski, PA; Pruszyńska-Oszmałek, E; Śliwowska, JH; Ziarniak, K | 1 |
| Cheng, L; Dong, H; Huang, D; Wang, Z; Yang, L; Yi, P | 1 |
| Goto, T; Hirabayashi, M; Ikegami, K; Inoue, N; Kobayashi, K; Majarune, S; Nagae, M; Nakamura, S; Okamoto, S; Sanbo, M; Tsuchida, H; Tsukamura, H; Uenoyama, Y | 1 |
| Iwata, K; Minabe, S; Ozawa, H; Tsuchida, H; Tsukamura, H | 1 |
| Anderson, RA; Skorupskaite, K | 1 |
| Coolen, LM; Lehman, MN; Lohr, DB; Moore, AM | 1 |
| Inoue, N; Nagae, M; Tsuchida, H; Tsukamura, H; Uenoyama, Y | 1 |
| Okamura, H; Wakabayashi, Y; Yamamura, T | 1 |
| Harlow, K; Knauer, MT; Lents, CA; Nestor, CC; Renwick, AN; Shuping, SL; Sommer, JR | 1 |
| Goto, T; Ikegami, K; Inoue, N; Nakamura, S; Tsukamura, H; Uenoyama, Y; Watanabe, Y | 1 |
| Goodman, RL; Herbison, AE; Lehman, MN; Navarro, VM | 1 |
| Griesgraber, MJ; Griffith, EH; Harlow, K; Hileman, SM; Nestor, CC; Seman, AD; Shuping, SL; Sommer, JR | 1 |
| Kanasaki, H; Kyo, S; Okada, H; Oride, A; Tumurbaatar, T; Tumurgan, Z | 1 |
| Abot, A; Dardente, H; Dufourny, L; Duittoz, A; Fleurot, R; Froment, P; Hellier, V; Knauf, C; Robert, V | 1 |
| Coutinho, EA; Esparza, LA; Hudson, AD; Kauffman, AS; Rizo, N; Steffen, P | 1 |
| Dhillo, WS; Mills, EG | 1 |
| Almeida, FRCL; Araujo-Lopes, R; Campideli-Santana, AC; Gusmao, DO; Szawka, RE | 1 |
| Ueta, Y | 1 |
| Abaraonye, I; Abbara, A; Bartram, S; Charalambides, MM; Koysombat, K; Lancaster, A; Murthy, S; Patel, B; Petitt, T; Pradeep, A; Stevenson, H; Vineall, O | 1 |
| Ishii, H; Iwata, K; Matsuda, F; Ogata, R; Ozawa, H; Sato, M | 1 |
| Moore, AM | 1 |
| Guru, S; Han, SY; Herbison, AE; Kim, JC; McQuillan, HJ; Morris, PG; Pardo-Navarro, M; Yeo, SH | 1 |
| Chen, Y; Hu, J; Li, J; Li, X; Li, Z; Xu, G; Zhao, X | 1 |
| Goodman, RL; Hileman, SM; Lehman, MN; Merkley, CM; Nestor, CC | 1 |
| Kimura, K; Matsuyama, S; Minabe, S; Nakamura, S; Ohkura, S | 1 |
| Tsukamura, H; Uenoyama, Y | 1 |
| Aerts, EG; Agus, S; Bowdridge, EC; Coolen, LM; Goodman, RL; Griesgraber, MJ; Hardy, SL; Hileman, SM; Lehman, MN; Moore, AM; Onslow, K; Walters, BA | 1 |
| Herbison, AE; Morris, PG | 1 |
| Enomoto, Y; Hirabayashi, M; Inoue, N; Kometani, M; Matsunaga, N; Matsuzaki, S; Nagae, M; Nonogaki, M; Panthee, A; Takizawa, M; Tsuchida, H; Tsukamura, H; Uenoyama, Y; Yamada, K | 1 |
32 review(s) available for neurokinin b and dynorphins
| Article | Year |
|---|---|
Neurokinin B signalling in human puberty.
Topics: Animals; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Median Eminence; Mutation; Neurokinin B; Puberty; Receptors, Neurokinin-3; Signal Transduction; Tachykinins | 2010 |
Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Feedback, Physiological; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Models, Biological; Neurokinin B; Periodicity; Tumor Suppressor Proteins | 2010 |
Male effect pheromone tickles the gonadotrophin-releasing hormone pulse generator.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Biological Clocks; Dynorphins; Electrophysiology; Female; Gonadotropin-Releasing Hormone; Humans; Male; Neurokinin B; Neurons; Ovulation; Periodicity; Pheromones; Signal Transduction | 2010 |
Neurokinin B and the hypothalamic regulation of reproduction.
Topics: Aging; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Female; Gene Expression; Humans; Hypothalamus; Kisspeptins; Macaca mulatta; Male; Neurokinin B; Neurons; Postmenopause; Pregnancy; Receptors, Neurokinin-3; Reproduction; Sex Characteristics; Signal Transduction; Terminology as Topic; Tumor Suppressor Proteins | 2010 |
Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus.
Topics: Animals; Dynorphins; Environment; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurobiology; Neurokinin B; Neurons; Steroids; Tumor Suppressor Proteins | 2010 |
Kisspeptins and the neuroendocrine control of reproduction.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Neurosecretory Systems; Neurotransmitter Agents; Reproduction; Tumor Suppressor Proteins | 2011 |
Kisspeptins and reproduction: physiological roles and regulatory mechanisms.
Topics: Animals; Dynorphins; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Hypothalamus; Kisspeptins; Male; Neural Pathways; Neurokinin B; Puberty; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reproduction; Sex Differentiation; Signal Transduction | 2012 |
Neuroanatomy of the kisspeptin signaling system in mammals: comparative and developmental aspects.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Axons; Dynorphins; Galanin; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Preoptic Area; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Signal Transduction; Third Ventricle | 2013 |
Kisspeptin and GnRH pulse generation.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Goats; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Male; Neurokinin B; Neurons; Ovulation; Spermatogenesis | 2013 |
Electrophysiology of kisspeptin neurons.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrous Cycle; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Kisspeptins; Male; Mice; N-Methylaspartate; Neurokinin B; Neurons; Reproduction | 2013 |
Reproductive neuropeptides: prevalence of GnRH and KNDy neural signalling components in a model avian, gallus gallus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Chickens; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neuropeptides; Reproduction | 2013 |
Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: a novel hypothesis on the mechanism of hot flushes.
Topics: Animals; Body Temperature Regulation; Dynorphins; Estradiol; Estrous Cycle; Female; Hot Flashes; Humans; Hypothalamus; Kisspeptins; Luteinizing Hormone; Models, Biological; Neurokinin B; Neurons; Ovariectomy; Postmenopause; Preoptic Area; Rats; Receptors, Neurokinin-3; Signal Transduction; Skin; Tail; Vasodilation | 2013 |
A role for neurokinin B in pulsatile GnRH secretion in the ewe.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Neurons; Receptors, Neurokinin-3; Sheep; Signal Transduction | 2014 |
The role of neurokinin B signalling in reproductive neuroendocrinology.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Kisspeptins; Luteinizing Hormone; Male; Mice; Neuroendocrinology; Neurokinin B; Pituitary-Adrenal System; Rats; Reproduction; Signal Transduction | 2014 |
KNDy neuron as a gatekeeper of puberty onset.
Topics: Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Neurons; Puberty; Sexual Maturation | 2014 |
Neurokinin B and reproductive functions: "KNDy neuron" model in mammals and the emerging story in fish.
Topics: Animals; Dynorphins; Fishes; Mammals; Neurokinin B; Neurons; Reproduction | 2014 |
Control of the onset of puberty.
Topics: Animals; Dynorphins; Estradiol; Gene Expression Regulation, Developmental; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neuropeptides; Pituitary Gland; Puberty; Sexual Maturation | 2016 |
Regulation of GnRH pulsatility in ewes.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Breeding; Dynorphins; Estradiol; Estrous Cycle; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Homeostasis; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Periodicity; Progesterone; Seasons; Sexual Maturation; Sheep | 2018 |
The role of kisspeptin/neurokinin B/dynorphin neurons in pathomechanism of vasomotor symptoms in postmenopausal women: from physiology to potential therapeutic applications.
Topics: Dynorphins; Feedback, Physiological; Female; Hot Flashes; Humans; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Postmenopause; Vasomotor System | 2018 |
The role of neuropeptides and neurotransmitters on kisspeptin/kiss1r-signaling in female reproduction.
Topics: Animals; Dynorphins; Female; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Receptors, Kisspeptin-1; Reproduction; Signal Transduction | 2018 |
KNDy Cells Revisited.
Topics: Animals; Dynorphins; Estrogens; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Progesterone; Reproduction; Testosterone | 2018 |
The neurobiological mechanism underlying hypothalamic GnRH pulse generation: the role of kisspeptin neurons in the arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Mice; Neurokinin B; Neurons | 2019 |
Does the KNDy Model for the Control of Gonadotropin-Releasing Hormone Pulses Apply to Monkeys and Humans?
Topics: Animals; Dynorphins; Female; Gonadotropin-Releasing Hormone; Haplorhini; Humans; Hypothalamus; Kisspeptins; Male; Neurokinin B | 2019 |
Metabolic regulation of kisspeptin - the link between energy balance and reproduction.
Topics: Animals; Dynorphins; Energy Metabolism; Female; Gonadotropin-Releasing Hormone; Homeostasis; Humans; Hypothalamo-Hypophyseal System; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Ovary; Puberty; Reproduction | 2020 |
Hypothalamic neurokinin signalling and its application in reproductive medicine.
Topics: Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Male; Neurokinin B; Reproductive Medicine | 2022 |
Role of KNDy Neurons Expressing Kisspeptin, Neurokinin B, and Dynorphin A as a GnRH Pulse Generator Controlling Mammalian Reproduction.
Topics: Animals; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Kisspeptins; Mammals; Neurokinin B; Neurons; Reproduction | 2021 |
Cellular and molecular mechanisms regulating the KNDy neuronal activities to generate and modulate GnRH pulse in mammals.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Mammals; Neurokinin B; Neurons | 2022 |
Neuroendocrine control of gonadotropin-releasing hormone: Pulsatile and surge modes of secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dendrimers; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Mice; Neurokinin B; Rats; Sheep | 2022 |
Invited review: Translating kisspeptin and neurokinin B biology into new therapies for reproductive health.
Topics: Animals; Biology; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Male; Mammals; Neurokinin B; Reproduction; Reproductive Health | 2022 |
Kisspeptin-neuron control of LH pulsatility and ovulation.
Topics: Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons | 2022 |
KNDy neurons as the GnRH pulse generator: Recent studies in ruminants.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neurons; Ruminants | 2023 |
KNDy neurones and GnRH/LH pulse generation: Current understanding and future aspects.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Mammals; Neurokinin B; Neurons; Reproduction | 2023 |
1 trial(s) available for neurokinin b and dynorphins
| Article | Year |
|---|---|
κ Agonists as a novel therapy for menopausal hot flashes.
Topics: Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hot Flashes; Humans; Kisspeptins; Luteinizing Hormone; Middle Aged; Neurokinin B; Neurons; Pentazocine; Placebos; Postmenopause; Receptors, Opioid, kappa | 2015 |
87 other study(ies) available for neurokinin b and dynorphins
| Article | Year |
|---|---|
Functional characterization by heterologous expression of a novel cloned tachykinin peptide receptor.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cloning, Molecular; DNA, Complementary; Dynorphins; Membrane Potentials; Mice; Molecular Sequence Data; Neurokinin B; Oocytes; Rats; Receptors, Opioid, kappa; Receptors, Tachykinin; Xenopus laevis | 1996 |
Preprodynorphin-, preproenkephalin-, preprotachykinin A- and preprotachykinin B-immunoreactive neurons in the accumbens nucleus and olfactory tubercle: double-immunofluorescence analysis.
Topics: Animals; Dynorphins; Enkephalins; Fluorescent Antibody Technique; Immunohistochemistry; Neurokinin B; Neurons; Nucleus Accumbens; Olfactory Pathways; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Tachykinins | 2002 |
Chemical organization of projection neurons in the rat accumbens nucleus and olfactory tubercle.
Topics: Animals; Basal Ganglia; Dynorphins; Enkephalins; Fluorescent Antibody Technique; Immunoenzyme Techniques; Immunohistochemistry; Male; Neural Pathways; Neurokinin B; Neurons; Nucleus Accumbens; Olfactory Pathways; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Tachykinins | 2003 |
Colocalisation of dynorphin a and neurokinin B immunoreactivity in the arcuate nucleus and median eminence of the sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Hypothalamus; Immunohistochemistry; Median Eminence; Neural Pathways; Neurokinin B; Neurons; Sheep; Tissue Distribution | 2006 |
An androgen-dependent sexual dimorphism visible at puberty in the rat hypothalamus.
Topics: Analysis of Variance; Androgens; Animals; Animals, Newborn; Castration; Dynorphins; Female; Gene Expression Regulation, Developmental; Hypothalamus; Male; Models, Biological; Neurokinin B; Rats; Rats, Wistar; Sex Characteristics; Time Factors | 2007 |
Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; gamma-MSH; Immunohistochemistry; In Vitro Techniques; Kisspeptins; Male; Neurokinin B; Neurons; Sheep; Tumor Suppressor Proteins | 2007 |
Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback.
Topics: Aging; Animals; Dynorphins; Estrogens; Feedback, Physiological; Female; Humans; Hypothalamus; Kisspeptins; Menopause; Middle Aged; Neurokinin B; Neurons; Neurosecretory Systems; Ovary; Rats; Substance P; Tumor Suppressor Proteins | 2009 |
Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estradiol; Female; Gonadotropin-Releasing Hormone; In Situ Hybridization; Kisspeptins; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Neurokinin B; Neurons; Ovariectomy; Protein Precursors; Receptors, Neurokinin-3; Receptors, Opioid; RNA, Messenger; Signal Transduction; Tumor Suppressor Proteins | 2009 |
The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus: sex differences and effects of prenatal testosterone in sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Neurons; Oligopeptides; Pregnancy; Prenatal Exposure Delayed Effects; Sex Characteristics; Sheep; Testosterone | 2010 |
Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Biological Clocks; Dynorphins; Electrophysiology; Estrous Cycle; Female; Goats; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Neurosecretory Systems; Ovariectomy; Periodicity; Proteins; Reproduction; Tumor Suppressor Proteins | 2010 |
Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Feedback, Physiological; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Neurokinin B; Neurons; Receptors, Estrogen; Receptors, Progesterone; Signal Transduction | 2011 |
The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Narcotic Antagonists; Neurokinin B; Ovariectomy; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Receptors, Opioid; Receptors, Opioid, kappa; Signal Transduction; Substance P | 2012 |
Arcuate kisspeptin/neurokinin B/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dynorphins; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Immunohistochemistry; Immunotoxins; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Neuropeptide Y; Ovariectomy; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins | 2012 |
Role of Neurokinin B and Dynorphin A in pituitary gonadotroph and somatolactotroph cell lines.
Topics: Animals; Cell Line; Dynorphins; Gonadotrophs; Gonadotropins; Lactotrophs; Neurokinin B; Nociceptin Receptor; Pituitary Gland; Prolactin; Promoter Regions, Genetic; Rats; Receptors, Opioid; Receptors, Tachykinin; Somatotrophs; Transfection | 2012 |
Low degree of overlap between kisspeptin, neurokinin B, and dynorphin immunoreactivities in the infundibular nucleus of young male human subjects challenges the KNDy neuron concept.
Topics: Adult; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Male; Nerve Fibers; Neurokinin B; Neurons | 2012 |
KNDy (kisspeptin/neurokinin B/dynorphin) neurons are activated during both pulsatile and surge secretion of LH in the ewe.
Topics: Animals; Dynorphins; Estrous Cycle; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Pituitary Gland, Anterior; Proto-Oncogene Proteins c-fos; Sheep | 2012 |
Electrophysiological and morphological evidence for synchronized GnRH pulse generator activity among Kisspeptin/neurokinin B/dynorphin A (KNDy) neurons in goats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Axons; Dynorphins; Electrodes; Electrophysiological Phenomena; Female; Gene Expression Regulation, Developmental; Goats; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Neurokinin B; Neurons; Peptide Fragments; Pheromones; Substance P | 2013 |
dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cerebral Ventricles; Dynorphins; Estrogens; Feedback, Physiological; Female; Gene Expression Regulation, Developmental; In Situ Hybridization; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Ovariectomy; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Opioid, kappa; RNA, Messenger; Signal Transduction; Tachykinins | 2013 |
Interactions between kisspeptins and neurokinin B.
Topics: Animals; Dynorphins; gamma-Aminobutyric Acid; Glutamic Acid; Gonadal Steroid Hormones; Humans; Kisspeptins; Luteinizing Hormone; Mutation; Neurokinin B; Neurons; Peptide Fragments; Puberty; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Rodentia; Sexual Maturation; Substance P | 2013 |
Neurokinin B activates arcuate kisspeptin neurons through multiple tachykinin receptors in the male mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Green Fluorescent Proteins; Kisspeptins; Male; Membrane Potentials; Mice; Mice, Transgenic; Neurokinin B; Neurons; Oligopeptides; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Quinolines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Receptors, Tachykinin; Substance P | 2013 |
Regulation of arcuate neurons coexpressing kisspeptin, neurokinin B, and dynorphin by modulators of neurokinin 3 and κ-opioid receptors in adult male mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Benzeneacetamides; Dynorphins; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Kisspeptins; Male; Membrane Potentials; Mice; Mice, Transgenic; Neurokinin B; Neurons; Orchiectomy; Peptide Fragments; Pyrrolidines; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Substance P; Time Factors | 2013 |
Chronic peripheral administration of kappa-opioid receptor antagonist advances puberty onset associated with acceleration of pulsatile luteinizing hormone secretion in female rats.
Topics: Animals; Drug Implants; Dynorphins; Female; Luteinizing Hormone; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Neurokinin B; Neurons; Ovary; Peptide Fragments; Puberty, Precocious; Random Allocation; Rats; Rats, Wistar; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Sexual Maturation; Signal Transduction; Substance P; Weaning | 2013 |
Kisspeptin, neurokinin B, and dynorphin act in the arcuate nucleus to control activity of the GnRH pulse generator in ewes.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; N-Methylaspartate; Neurokinin B; Neurons; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Sheep | 2013 |
New developments in kisspeptin, neurokinin B and dynorphin A regulation of gonadotropin-releasing hormone pulsatile secretion.
Topics: Animals; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Rats; Sheep; Signal Transduction | 2014 |
Photoperiodic co-regulation of kisseptin, neurokinin B and dynorphin in the hypothalamus of a seasonal rodent.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cricetinae; Dorsomedial Hypothalamic Nucleus; Dynorphins; Gene Expression Regulation; Kisspeptins; Male; Mesocricetus; Neurokinin B; Neurons; Neuropeptides; Photoperiod; Seasons | 2014 |
Disparate changes in kisspeptin and neurokinin B expression in the arcuate nucleus after sex steroid manipulation reveal differential regulation of the two KNDy peptides in rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Castration; Cell Count; Dynorphins; Female; Gonadal Steroid Hormones; Kisspeptins; Male; Neurokinin B; Neurons; Rats; Rats, Wistar; Sex Characteristics | 2014 |
Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats.
Topics: Aging; Animals; Dynorphins; Enkephalins; Female; Follicle Stimulating Hormone; Hypothalamus; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Peptide Fragments; Protein Precursors; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 2015 |
Prenatal testosterone excess decreases neurokinin 3 receptor immunoreactivity within the arcuate nucleus KNDy cell population.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Fetus; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Pregnancy; Receptors, Neurokinin-3; Sheep; Testosterone | 2015 |
Chronic oestradiol reduces the dendritic spine density of KNDy (kisspeptin/neurokinin B/dynorphin) neurones in the arcuate nucleus of ovariectomised Tac2-enhanced green fluorescent protein transgenic mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dendritic Spines; Down-Regulation; Dynorphins; Estradiol; Female; Green Fluorescent Proteins; Kisspeptins; Male; Mice; Mice, Transgenic; Neurokinin B; Neurons; Ovariectomy; Pregnancy; Protein Precursors; Tachykinins; Time Factors; Transgenes | 2015 |
Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Immunohistochemistry; In Situ Hybridization; Kisspeptins; Luteinizing Hormone; Models, Animal; Neurokinin B; Neurons; Neurotransmitter Agents; Ovariectomy; Peptide Fragments; Receptors, Neurokinin-3; RNA, Messenger; Sheep; Substance P | 2015 |
Evidence for Changes in Numbers of Synaptic Inputs onto KNDy and GnRH Neurones during the Preovulatory LH Surge in the Ewe.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Ovulation; Preoptic Area; Sheep; Vesicular Glutamate Transport Protein 2 | 2015 |
Prenatal Testosterone Treatment Leads to Changes in the Morphology of KNDy Neurons, Their Inputs, and Projections to GnRH Cells in Female Sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Disease Models, Animal; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neurons; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Preoptic Area; Sheep; Testosterone | 2015 |
Does salt have a permissive role in the induction of puberty?
Topics: Age Factors; Animals; Arcuate Nucleus of Hypothalamus; Body Mass Index; Child; Diet; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Male; Mice; Neurokinin B; Neurons; Obesity; Puberty; Rats; Reproduction; Sexual Maturation; Sodium Chloride, Dietary | 2015 |
KNDy Neurons Modulate the Magnitude of the Steroid-Induced Luteinizing Hormone Surges in Ovariectomized Rats.
Topics: Animals; Dynorphins; Female; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Ovariectomy; Pituitary Gland; Rats; Rats, Wistar | 2015 |
Both Estrogen and Androgen Modify the Response to Activation of Neurokinin-3 and κ-Opioid Receptors in Arcuate Kisspeptin Neurons From Male Mice.
Topics: Androgens; Animals; Arcuate Nucleus of Hypothalamus; Dihydrotestosterone; Dynorphins; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Neurokinin B; Neurons; Orchiectomy; Patch-Clamp Techniques; Peptide Fragments; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Receptors, Steroid; Substance P | 2016 |
Immunoelectron microscopic observation of the subcellular localization of kisspeptin, neurokinin B and dynorphin A in KNDy neurons in the arcuate nucleus of the female rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Kisspeptins; Microscopy, Immunoelectron; Neurokinin B; Neurons; Rats, Wistar | 2016 |
Ablation of KNDy Neurons Results in Hypogonadotropic Hypogonadism and Amplifies the Steroid-Induced LH Surge in Female Rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dynorphins; Estradiol; Estrous Cycle; Female; Hypogonadism; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Progesterone; Rats; Rats, Sprague-Dawley | 2016 |
Immunohistochemical characterization of the arcuate kisspeptin/neurokinin B/dynorphin (KNDy) and preoptic kisspeptin neuronal populations in the hypothalamus during the estrous cycle in heifers.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Breeding; Cattle; Dynorphins; Estradiol; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Immunohistochemistry; Kisspeptins; Neurokinin B; Neurons; Preoptic Area; Progesterone; Radioimmunoassay | 2016 |
The interaction of fasting, caloric restriction, and diet-induced obesity with 17β-estradiol on the expression of KNDy neuropeptides and their receptors in the female mouse.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Composition; Body Weight; Caloric Restriction; Diet; Diet, High-Fat; Dynorphins; Estradiol; Fasting; Female; Gene Expression Profiling; Gene Expression Regulation; Ghrelin; Kisspeptins; Mice, Inbred C57BL; Models, Biological; Neurokinin B; Neurons; Neuropeptides; Obesity; Organ Size; Signal Transduction | 2016 |
Prenatal testosterone exposure decreases colocalization of insulin receptors in kisspeptin/neurokinin B/dynorphin and agouti-related peptide neurons of the adult ewe.
Topics: Aging; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Receptor, Insulin; Sheep; Testosterone | 2016 |
A kiss to set the rhythm.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Channelrhodopsins; Dynorphins; Excitatory Postsynaptic Potentials; Female; Fertility; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Kisspeptins; Light; Male; Mice; Neurokinin B; Neurons; Optogenetics; Ovary; Periodicity; Pituitary Gland; Reproduction; Signal Transduction; Testis | 2016 |
Age-related alterations in hypothalamic kisspeptin, neurokinin B, and dynorphin neurons and in pulsatile LH release in female and male rats.
Topics: Aging; Animals; Dynorphins; Female; Histocytochemistry; Hypothalamus; Kisspeptins; Luteinizing Hormone; Male; Menopause; Neurokinin B; Neurons; Pulsatile Flow; Rats, Wistar | 2017 |
Effects of Orchidectomy and Testosterone Replacement on Numbers of Kisspeptin-, Neurokinin B-, and Dynorphin A-Immunoreactive Neurones in the Arcuate Nucleus of the Hypothalamus in Obese and Diabetic Rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diabetes Mellitus, Experimental; Diet, High-Fat; Dynorphins; Kisspeptins; Male; Neurokinin B; Neurons; Obesity; Orchiectomy; Rats; Testosterone | 2017 |
Effects of Season and Estradiol on KNDy Neuron Peptides, Colocalization With D2 Dopamine Receptors, and Dopaminergic Inputs in the Ewe.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dopaminergic Neurons; Dynorphins; Estradiol; Female; Kisspeptins; Neurokinin B; Neurons; Ovariectomy; Receptors, Dopamine D2; Reproduction; Seasons; Sheep | 2017 |
Evidence of involvement of neurone-glia/neurone-neurone communications via gap junctions in synchronised activity of KNDy neurones.
Topics: Animals; Cells, Cultured; Connexins; Dynorphins; Gap Junctions; Glycyrrhetinic Acid; Kisspeptins; Medulla Oblongata; Mefloquine; Mice, Transgenic; Neuroglia; Neurokinin B; Neurons; Peptide Fragments; Substance P | 2017 |
KNDy neurone activation prior to the LH surge of the ewe is disrupted by LPS.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Crosses, Genetic; Dynorphins; Female; Fluorescent Antibody Technique; Follicular Phase; Gonadotropin-Releasing Hormone; Immunohistochemistry; Injections, Intravenous; Kisspeptins; Lipopolysaccharides; Luteinizing Hormone; Nerve Tissue Proteins; Neurokinin B; Neurons; Ovary; Ovulation; Pituitary Gland; Sheep, Domestic | 2017 |
Long-Term Recordings of Arcuate Nucleus Kisspeptin Neurons Reveal Patterned Activity That Is Modulated by Gonadal Steroids in Male Mice.
Topics: Action Potentials; Androgens; Animals; Arcuate Nucleus of Hypothalamus; Brain; Cluster Analysis; Dihydrotestosterone; Dynorphins; Estradiol; Estrogens; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Kisspeptins; Male; Mice; Mice, Transgenic; Neurokinin B; Neurons; Orchiectomy; Patch-Clamp Techniques; Receptors, Neurokinin-3 | 2017 |
Distinct dynorphin expression patterns with low- and high-dose estrogen treatment in the arcuate nucleus of female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estradiol; Female; Gene Expression Regulation; Immunohistochemistry; In Situ Hybridization; Kisspeptins; Neurokinin B; Neurons; Ovariectomy; Rats; RNA, Messenger | 2017 |
The effects of chronic testosterone administration on hypothalamic gonadotropin-releasing hormone regulatory factors (Kiss1, NKB, pDyn and RFRP) and their receptors in female rats.
Topics: Animals; Dynorphins; Estradiol; Female; Hypothalamus; Kisspeptins; Leptin; Luteinizing Hormone; Neurokinin B; Neurons; Rats; Rats, Wistar; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Testosterone | 2018 |
Expression of hypothalamic kisspeptin, neurokinin B, and dynorphin A neurons attenuates in female Zucker fatty rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Rats; Rats, Zucker | 2018 |
Three-dimensional imaging of KNDy neurons in the mammalian brain using optical tissue clearing and multiple-label immunocytochemistry.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Imaging, Three-Dimensional; Immunohistochemistry; Kisspeptins; Neurokinin B; Rats; Rats, Sprague-Dawley; Sheep | 2018 |
Evidence That Dynorphin Acts Upon KNDy and GnRH Neurons During GnRH Pulse Termination in the Ewe.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Neurokinin B; Neurons; Receptors, Opioid, kappa; Sheep | 2018 |
Central Orexin A Affects Reproductive Axis by Modulation of Hypothalamic Kisspeptin/Neurokinin B/Dynorphin Secreting Neurons in the Male Wistar Rats.
Topics: Animals; Benzoxazoles; Dioxanes; Dynorphins; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Hypothalamus; Injections, Intraventricular; Kisspeptins; Luteinizing Hormone; Male; Naphthyridines; Neurokinin B; Neurons; Orexins; Phenylurea Compounds; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reproduction; Sexual Behavior, Animal; Testosterone; Urea | 2018 |
High-fat diet and type 2 diabetes induced disruption of the oestrous cycle and alteration of hormonal profiles, but did not affect subpopulations of KNDy neurones in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diabetes Mellitus, Type 2; Diet, High-Fat; Dynorphins; Estrous Cycle; Female; Insulin; Kisspeptins; Leptin; Neurokinin B; Neurons; Neuropeptides; Peptide Hormones; Rats, Wistar | 2018 |
Glutamatergic Neurokinin 3 Receptor Neurons in the Median Preoptic Nucleus Modulate Heat-Defense Pathways in Female Mice.
Topics: Animals; Body Temperature Regulation; Dynorphins; Female; Glutamic Acid; Hot Flashes; Hot Temperature; Kisspeptins; Mice; Neurokinin B; Neurons; Preoptic Area; Proto-Oncogene Proteins c-fos; Receptors, Neurokinin-3 | 2019 |
Neonatal Estrogen Causes Irreversible Male Infertility via Specific Suppressive Action on Hypothalamic Kiss1 Neurons.
Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; Dynorphins; Estradiol; Gene Expression Regulation, Developmental; In Situ Hybridization; Infertility, Male; Kisspeptins; Male; Neurokinin B; Neurons; Rats, Wistar; Spermatogenesis; Testosterone | 2019 |
Hypothalamic Reproductive Endocrine Pulse Generator Activity Independent of Neurokinin B and Dynorphin Signaling.
Topics: Academic Medical Centers; Adolescent; Adult; Animals; Case-Control Studies; Child; Disease Models, Animal; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Kisspeptins; Luteinizing Hormone; Mice; Mice, Knockout; Narcotic Antagonists; Neurokinin B; Neurons; Signal Transduction; Substance P; Treatment Outcome; Young Adult | 2019 |
Prenatal Testosterone Exposure Alters GABAergic Synaptic Inputs to GnRH and KNDy Neurons in a Sheep Model of Polycystic Ovarian Syndrome.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Disease Models, Animal; Dynorphins; Female; GABAergic Neurons; Gonadotropin-Releasing Hormone; K Cl- Cotransporters; Kisspeptins; Neurokinin B; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Preoptic Area; Sheep; Solute Carrier Family 12, Member 2; Symporters; Testosterone | 2019 |
Kisspeptin/Neurokinin B/Dynorphin (KNDy) cells as integrators of diverse internal and external cues: evidence from viral-based monosynaptic tract-tracing in mice.
Topics: Animals; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Male; Mice; Neurokinin B; Neurons; Reproduction; Sex Characteristics | 2019 |
The Origin of GnRH Pulse Generation: An Integrative Mathematical-Experimental Approach.
Topics: Animals; Dynorphins; Estrous Cycle; Feedback, Physiological; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Theoretical; Neurokinin B; Neurons; Optogenetics; Pregnancy; Reproduction; Ultradian Rhythm | 2019 |
Reproductive status-dependent dynorphin and neurokinin B gene expression in female Damaraland mole-rats.
Topics: Animals; Brain; Dynorphins; Female; Gene Expression Regulation; Mole Rats; Neurokinin B; Neurons; Phosphorylation; Reproduction | 2019 |
Regulation of prepubertal dynorphin secretion in the medial basal hypothalamus of the female rat.
Topics: Animals; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Insulin-Like Growth Factor I; Microinjections; Neurokinin B; Peptide Fragments; Peptides; Rats; Receptor, IGF Type 1; Receptors, Neurokinin-3; Receptors, Opioid; Sexual Maturation; Substance P; Up-Regulation | 2019 |
Hyperactive LH Pulses and Elevated Kisspeptin and NKB Gene Expression in the Arcuate Nucleus of a PCOS Mouse Model.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aromatase Inhibitors; Disease Models, Animal; Dynorphins; Female; Gene Expression; Kisspeptins; Letrozole; Luteinizing Hormone; Mice; Neurokinin B; Neurons; Polycystic Ovary Syndrome | 2020 |
Central injection of neuropeptide Y modulates sexual behavior in male rats: interaction with GnRH and kisspeptin/neurokinin B/dynorphin.
Topics: Animals; Dynorphins; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Male; Neurokinin B; Neuropeptide Y; Rats, Wistar; Sexual Behavior, Animal; Signal Transduction | 2021 |
Establishment of immortalised cell lines derived from female Shiba goat KNDy and GnRH neurones.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cell Line, Transformed; Dynorphins; Female; Goats; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B; Neurons; Primary Cell Culture | 2020 |
Effects of Ovariectomy and Sex Hormone Replacement on Numbers of Kisspeptin-, Neurokinin B- and Dynorphin A-immunoreactive Neurons in the Arcuate Nucleus of the Hypothalamus in Obese and Diabetic Rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diabetes Mellitus, Experimental; Dynorphins; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Neurokinin B; Neurons; Obesity; Ovariectomy; Rats | 2020 |
Effect of electroacupuncture on the kisspeptin system in a pubertal rat model of polycystic ovary syndrome.
Topics: Acupuncture Points; Animals; Dynorphins; Electroacupuncture; Estrous Cycle; Female; Follicle Stimulating Hormone; Humans; Hypothalamus; Kisspeptins; Luteinizing Hormone; Neurokinin B; Ovary; Polycystic Ovary Syndrome; Pregnancy; Puberty; Rats; Rats, Sprague-Dawley | 2021 |
Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aromatase; Dynorphins; Feedback, Physiological; Female; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Gonadotropin-Releasing Hormone; Gonadotropins; Integrases; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Organ Size; Organogenesis; Ovarian Follicle; Pituitary Gland; Rats; Receptors, LH; Receptors, LHRH; RNA, Messenger | 2021 |
Effect of diet-induced obesity on kisspeptin-neurokinin B-dynorphin A neurons in the arcuate nucleus and luteinizing hormone secretion in sex hormone-primed male and female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Diet, High-Fat; Dynorphins; Female; Gonadal Steroid Hormones; Hypogonadism; Kisspeptins; Luteinizing Hormone; Male; Metabolic Diseases; Neurokinin B; Neurons; Obesity; Rats; Rats, Wistar | 2021 |
Prenatal Androgen Exposure Alters KNDy Neurons and Their Afferent Network in a Model of Polycystic Ovarian Syndrome.
Topics: Afferent Pathways; Androgens; Animals; Disease Models, Animal; Dynorphins; Female; Kisspeptins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurokinin B; Neurons; Neurons, Afferent; Neurosecretory Systems; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects | 2021 |
Local administration of Neurokinin B in the arcuate nucleus accelerates the neural activity of the GnRH pulse generator in goats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Goats; Gonadotropin-Releasing Hormone; Kisspeptins; Neurokinin B | 2021 |
Evidence that pubertal status impacts kisspeptin/neurokinin B/dynorphin neurons in the gilt†.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Kisspeptins; Neurokinin B; Neurons; Sexual Maturation; Sus scrofa | 2021 |
In vivo imaging of the GnRH pulse generator reveals a temporal order of neuronal activation and synchronization during each pulse.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Neurokinin B; Neurons; Reproduction | 2022 |
The impact of undernutrition on KNDy (kisspeptin/neurokinin B/dynorphin) neurons in female lambs.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Malnutrition; Neurokinin B; Neurons; RNA, Messenger; Sheep | 2022 |
Hyperandrogenism induces proportional changes in the expression of Kiss-1, Tac2, and DynA in hypothalamic KNDy neurons.
Topics: Androgens; Animals; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hyperandrogenism; Hypothalamus; Kisspeptins; Mice; Neurokinin B; Neurons; Rats; Tachykinins; Testosterone | 2022 |
How does apelin affect LH levels? An investigation at the level of GnRH and KNDy neurons.
Topics: Animals; Apelin; Apelin Receptors; Arcuate Nucleus of Hypothalamus; Colforsin; Dynorphins; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Male; Mice; Neurokinin B; Neurons; Rats; Steroids | 2022 |
Conditional Deletion of KOR (Oprk1) in Kisspeptin Cells Does Not Alter LH Pulses, Puberty, or Fertility in Mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Fertility; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Luteinizing Hormone; Male; Mice; Neurokinin B; Receptors, Opioid, kappa; Sexual Maturation | 2022 |
Partial loss of arcuate kisspeptin neurons in female rats stimulates luteinizing hormone and decreases prolactin secretion induced by estradiol.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estradiol; Female; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Prolactin; Rats; Tyrosine 3-Monooxygenase | 2022 |
Sex-related differences in obesity - role of the kisspeptin-neurokinin B-dynorphin A (KNDy) neurons.
Topics: Arcuate Nucleus of Hypothalamus; Dynorphins; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Neurokinin B; Neurons; Obesity | 2023 |
Short-term depletion of plasma estrogen affects hypothalamic kisspeptin-neurokinin B-dynorphin A neurons, gonadotrophs, and pulsatile luteinizing hormone secretion in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Female; Gonadotrophs; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Rats | 2023 |
GnRH Pulse Generation in Rodents: Time to Terminate the Role of Dynorphin?
Topics: Animals; Dynorphins; Fertility; Gonadotropin-Releasing Hormone; Kisspeptins; Mice; Neurokinin B; Rodentia; Sexual Maturation | 2023 |
Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Glutamates; Hormones; Kisspeptins; Male; Mammals; Mice; Neurokinin B; Neurons | 2023 |
Effects of electroacupuncture on the kisspeptin-gonadotropin-releasing hormone (GnRH) /luteinizing hormone (LH) neural circuit abnormalities and androgen receptor expression of kisspeptin/neurokinin B/dynorphin neurons in PCOS rats.
Topics: Androgens; Animals; Dynorphins; Electroacupuncture; Estrogen Receptor alpha; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Hyperandrogenism; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Kisspeptin-1; RNA, Messenger | 2023 |
Effect of a neurokinin 3 receptor-selective agonist administration on the embryos recovered from superovulated cows.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cattle; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Mammals; Neurokinin B; Receptors, Neurokinin-3 | 2023 |
Lesions of KNDy and Kiss1R Neurons in the Arcuate Nucleus Produce Different Effects on LH Pulse Patterns in Female Sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; gamma-Aminobutyric Acid; Glutamates; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Receptors, Kisspeptin-1; RNA, Messenger; Saporins; Sheep | 2023 |
Mechanism of Arcuate Kisspeptin Neuron Synchronization in Acute Brain Slices From Female Mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Brain; Dynorphins; Female; Glutamates; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Neurokinin B; Neurons | 2023 |
Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Rats | 2023 |