Compounds > neurokinin a (4-10), beta-ala(8)-

Page last updated: 2024-09-03

neurokinin a (4-10), beta-ala(8)- and sr 48968

neurokinin a (4-10), beta-ala(8)- has been researched along with sr 48968 in 14 studies

Compound Research Comparison

Studies (neurokinin a (4-10), beta-ala(8)-)	Trials (neurokinin a (4-10), beta-ala(8)-)	Recent Studies (post-2010) (neurokinin a (4-10), beta-ala(8)-)	Studies (sr 48968)	Trials (sr 48968)	Recent Studies (post-2010) (sr 48968)
71	0	2	338	2	13

Protein Interaction Comparison

Protein	Taxonomy	neurokinin a (4-10), beta-ala(8)- (IC50)	sr 48968 (IC50)
Substance-K receptor	Homo sapiens (human)		0.0001
Substance-P receptor	Homo sapiens (human)		0.8

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (71.43)	18.2507
2000's	4 (28.57)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Giachetti, A; Giuliani, S; Maggi, CA; Patacchini, R	1
Bartho, L; Giuliani, S; Maggi, CA; Santicioli, P	1
McKee, KT; Metters, KM; Millar, L; Rodger, IW	1
Basilisco, G; Phillips, SF	1
Brideau, C; Chan, CC; Guevremont, D; Hale, JJ; MacCoss, M; Rodger, IW; Tousignant, C	1
Astolfi, M; Goso, C; Manzini, S; Parlani, M	1
Cavero, I; Floch, A; Thiry, C	1
Giuliani, S; Lecci, A; Maggi, CA; Tramontana, M	1
Criscuoli, M; Giuliani, S; Lecci, A; Lippi, A; Maggi, CA; Patacchini, R; Santicioli, P; Tramontana, M	1
Aggio, A; Onori, L; Taddei, G; Tonini, M	1
Bialecki, R; Caccese, R; Graham, A	1
D'Agostino, G; Erbelding, D; Kilbinger, H	1
Krysiak, PS; Preiksaitis, HG	1
Couture, R; Deschamps, K	1

Other Studies

14 other study(ies) available for neurokinin a (4-10), beta-ala(8)- and sr 48968

Article	Year
In vivo and in vitro activity of SR 48,968, a non-peptide tachykinin NK-2 receptor antagonist. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Benzamides; Biphenyl Compounds; Blood Pressure; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Piperidines; Rats; Receptors, Neurokinin-2; Saliva; Substance P; Sulfones; Urinary Bladder	1993
Tachykinin NK-1 and NK-2 receptors in the circular muscle of the guinea-pig proximal colon. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Benzamides; Biphenyl Compounds; Colon; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Sulfones; Tetrodotoxin	1993
Identification of both NK1 and NK2 receptors in guinea-pig airways. British journal of pharmacology, 1993, Volume: 110, Issue:2 Topics: Animals; Benzamides; Chromatography, High Pressure Liquid; Guinea Pigs; In Vitro Techniques; Iodine Radioisotopes; Lung; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Radioligand Assay; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Respiratory System; Substance P; Trachea	1993
A selective NK-2 antagonist blocks the increase of canine colonic tone and ileal contractions induced by the NK-2 selective receptor agonist, [beta Ala8] neurokinin A-(4-10). Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:5 Topics: Animals; Benzamides; Colon; Dogs; Female; Gastrointestinal Motility; Ileum; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-2	1994
NK2 receptors mediate plasma extravasation in guinea-pig lower airways. British journal of pharmacology, 1993, Volume: 108, Issue:2 Topics: Animals; Benzamides; Blood Proteins; Bronchi; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Iodine Radioisotopes; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Receptors, Neurotransmitter	1993
[3H][beta-Ala8]neurokinin A-(4-10): a novel, selective radioligand for the tachykinin NK2 receptor. European journal of pharmacology, 1995, Dec-27, Volume: 294, Issue:1 Topics: Animals; Benzamides; Binding, Competitive; Cricetinae; In Vitro Techniques; Kinetics; Ligands; Male; Membranes; Mesocricetus; Muscle Contraction; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Urinary Bladder	1995
Pharmacological evidence that NK-2 tachykinin receptors mediate hypotension in the guinea pig but not in the rat. Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4 Topics: Animals; Benzamides; Blood Pressure; Guinea Pigs; Hypotension; Indoles; Isoindoles; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P	1996
Role of tachykinin NK1 and NK2 receptors on colonic motility in anesthetized rats: effect of agonists. Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:6 Topics: Anesthesia; Animals; Benzamides; Colon; Gastrointestinal Motility; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P	1997
Characterization of the antibronchoconstrictor activity of MEN 11420, a tachykinin NK2 receptor antagonist, in guinea-pigs. European journal of pharmacology, 1998, Jul-10, Volume: 352, Issue:2-3 Topics: Amino Acid Sequence; Animals; Atropine; Benzamides; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-2	1998
Contribution of NK(2) tachykinin receptors to propulsion in the rabbit distal colon. American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:1 Topics: Animals; Benzamides; Colon; Gastrointestinal Motility; In Vitro Techniques; Male; Muscle, Smooth; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Piperidines; Rabbits; Receptors, Neurokinin-2; Time Factors	2000
Pharmacological characterization of mucin secretion from CHO-K1-hNK(1)R cells. Neuropeptides, 1999, Volume: 33, Issue:3 Topics: Angiotensin II; Animals; Benzamides; Biological Transport; CHO Cells; Cricetinae; Endothelin-1; Glucosamine; Humans; Methacholine Chloride; Mucins; Muscarinic Agonists; Neurokinin A; Peptide Fragments; Phenylephrine; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Serotonin; Substance P; Transfection; Tritium; Vasoconstrictor Agents	1999
Tachykinin NK(2) receptors facilitate acetylcholine release from guinea-pig isolated trachea. European journal of pharmacology, 2000, May-12, Volume: 396, Issue:1 Topics: Acetylcholine; Animals; Benzamides; Capsaicin; Choline; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurokinin A; Neurons; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Trachea	2000
Tachykinins contribute to nerve-mediated contractions in the human esophagus. Gastroenterology, 2001, Volume: 120, Issue:1 Topics: Atropine; Autonomic Nervous System; Benzamides; Dose-Response Relationship, Drug; Esophagus; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Parasympatholytics; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Substance P; Tachykinins	2001
The ventral tegmental area as a putative target for tachykinins in cardiovascular regulation. British journal of pharmacology, 2005, Volume: 145, Issue:6 Topics: Acetates; Adrenergic beta-Antagonists; Animals; Atenolol; Behavior, Animal; Benzamides; Benzazepines; Blood Pressure; Dopamine D2 Receptor Antagonists; Glutamic Acid; Heart Rate; Indoles; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinolines; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Ventral Tegmental Area	2005