Page last updated: 2024-09-03

neurokinin a(4-10) and neurokinin a

neurokinin a(4-10) has been researched along with neurokinin a in 31 studies

Compound Research Comparison

Studies (neurokinin a(4-10))	Trials (neurokinin a(4-10))	Recent Studies (post-2010) (neurokinin a(4-10))	Studies (neurokinin a)	Trials (neurokinin a)	Recent Studies (post-2010) (neurokinin a)
34	0	0	1,765	34	91

Protein Interaction Comparison

Protein	Taxonomy	neurokinin a (IC50)
Substance-K receptor	Homo sapiens (human)	0.0017
Neuromedin-K receptor	Homo sapiens (human)	0.045
Substance-K receptor	Mesocricetus auratus (golden hamster)	0.001

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (12.90)	18.7374
1990's	22 (70.97)	18.2507
2000's	5 (16.13)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Buck, SH; Harbeson, SL; Le, TB; Shatzer, SA	1
Advenier, C; Bakdach, H; Brelière, JC; Emonds-Alt, X; Le Fur, G; Naline, E; Toty, L; Vilain, P	1
Giachetti, A; Giuliani, S; Maggi, CA; Mizrahi, J; Patacchini, R; Quartara, L; Renzetti, AR; Rovero, P	1
Ballati, L; Evangelista, S; Maggi, CA	1
Maggi, CA; Motta, A; Rovero, P; Saviano, G; Temussi, PA	1
Beaujouan, JC; Carruette, A; Chassaing, G; Garret, C; Lavielle, S; Loeuillet, D; Petitet, F; Robilliard, P; Saffroy, M; Torrens, Y	1
Giachetti, A; Maggi, CA; Meli, A; Patacchini, R	1
Beresford, IJ; Deal, MJ; Hagan, RM; Ireland, SJ; Jordan, CC; Ward, P	1
Constantine, JW; Lebel, WS; Woody, HA	1
Giachetti, A; Maggi, CA; Patacchini, R; Pestellini, V; Regoli, D; Rovero, P	1
Abelli, L; Ballati, L; Giachetti, A; Giuliani, S; Maggi, CA; Manzini, S; Meli, A; Rovero, P	1
Ballati, L; Conti, S; Maggi, CA; Manzini, S; Rovero, P	1
Couture, R; Drapeau, G; Guimond, C; Laneuville, O; Regoli, D	1
Casini, A; Geppetti, P; Maggi, CA; Surrenti, C	1
Hatae, Y; Kamiya, H; Kodama, H; Sakaguchi, K; Shimohigashi, Y; Takano, Y; Waki, M; Yamada, A	1
Beaujouan, JC; Glowinski, J; Petitet, F; Saffroy, M; Torrens, Y	1
Boucher, S; Couture, R; Gitter, BD; Howbert, JJ; Picard, P; Regoli, D	1
Liminga, U	1
Giuliani, S; Maggi, CA; Meini, S; Patacchini, R	1
Bertrand, C; Geppetti, P; Graf, PD; Nadel, JA	1
Champion, E; Foulon, DM; Jones, TR; Masson, P; Rodger, IW	1
De Giorgio, R; Giachetti, A; Maggi, CA; Patacchini, R	1
Barbanti, G; Giachetti, A; Giuliani, S; Maggi, CA; Patacchini, R; Quartara, L; Rovero, P; Turini, D	1
Goso, C; Maggi, CA; Patacchini, R; Quartara, L; Rovero, P	1
Betschart, J; Blanchard, JC; Garret, C; Grall, I; Piot, O; Ravard, S	1
Burcher, E; Comis, A; Matuszek, MA	1
Bozzi, A; Carnicelli, V; Delle Fave, G; Di Giulio, A; Oratore, A; Romano, G; Severi, C; Strom, R	1
Bergren, DR	1
Bueno, L; Carini, F; Crea, A; Criscuoli, M; D'Aranno, V; Fioramonti, J; Giuliani, S; Lecci, A; Maggi, CA; Marinoni, E; Tramontana, M	1
Burcher, E; Miller, RC; Warner, FJ	2

Other Studies

31 other study(ies) available for neurokinin a(4-10) and neurokinin a

Article	Year
A new class of high affinity ligands for the neurokinin A NK2 receptor: psi (CH2NR) reduced peptide bond analogues of neurokinin A4-10. Journal of medicinal chemistry, 1992, Oct-16, Volume: 35, Issue:21 Topics: Amino Acid Sequence; Animals; Cricetinae; In Vitro Techniques; Ligands; Molecular Sequence Data; Neurokinin A; Oxidation-Reduction; Peptide Fragments; Phosphatidylinositols; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Urinary Bladder	1992
Effects on the isolated human bronchus of SR 48968, a potent and selective nonpeptide antagonist of the neurokinin A (NK2) receptors. The American review of respiratory disease, 1992, Volume: 146, Issue:5 Pt 1 Topics: Acetylcholine; Amino Acid Sequence; Animals; Benzamides; Biphenyl Compounds; Bronchi; Bronchoconstriction; Cricetinae; Dinoprost; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation, Preclinical; Female; Histamine; Humans; In Vitro Techniques; Male; Middle Aged; Molecular Sequence Data; Neurokinin A; Peptide Fragments; Piperidines; Potassium Chloride; Racemases and Epimerases; Receptors, Neurokinin-2; Receptors, Neurotransmitter	1992
Heterogeneity of tachykinin NK-2 receptors in rabbit, guinea-pig and human smooth muscles. Neuropeptides, 1992, Volume: 23, Issue:3 Topics: Amino Acid Sequence; Animals; Guinea Pigs; Humans; Molecular Sequence Data; Muscle, Smooth; Neurokinin A; Peptide Fragments; Rabbits; Radioligand Assay; Receptors, Neurotransmitter; Receptors, Tachykinin; Tachykinins	1992
Effect of ruthenium red on the bronchoconstriction induced by capsaicin and by selective tachykinin receptor agonists in anaesthetized guinea-pig. Journal of autonomic pharmacology, 1992, Volume: 12, Issue:5 Topics: Anesthesia; Animals; Bronchial Spasm; Bronchoconstriction; Capsaicin; Guanethidine; Guinea Pigs; Male; Neurokinin A; Peptide Fragments; Propranolol; Receptors, Neurotransmitter; Receptors, Tachykinin; Ruthenium Red	1992
Conformation-activity relationship of tachykinin neurokinin A (4-10) and of some [Xaa8] analogues. Biochemistry, 1991, Oct-22, Volume: 30, Issue:42 Topics: Amino Acid Sequence; Animals; Dimethyl Sulfoxide; Guinea Pigs; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Neurokinin A; Peptide Fragments; Protein Conformation; Rabbits; Structure-Activity Relationship	1991
Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides, 1991, Volume: 19, Issue:2 Topics: Amino Acid Sequence; Animals; Binding Sites; Biological Assay; Guinea Pigs; Molecular Sequence Data; Neurokinin A; Neurokinin B; Peptide Fragments; Portal Vein; Rabbits; Radioimmunoassay; Rats; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Receptors, Tachykinin; Structure-Activity Relationship; Tachykinins	1991
Tachykinin receptors in the circular muscle of the guinea-pig ileum. British journal of pharmacology, 1990, Volume: 101, Issue:4 Topics: Animals; Atropine; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tetrodotoxin	1990
Receptor-selective, peptidase-resistant agonists at neurokinin NK-1 and NK-2 receptors: new tools for investigating neurokinin function. Neuropeptides, 1991, Volume: 19, Issue:2 Topics: Administration, Cutaneous; Amino Acid Sequence; Animals; Bronchoconstriction; Capillary Permeability; Chromatography, High Pressure Liquid; Guinea Pigs; Male; Molecular Sequence Data; Neurokinin A; Neurokinin B; Peptide Fragments; Rats; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Trachea	1991
Inhibition of tachykinin-induced hypotension in dogs by CP-96,345, a selective blocker of NK-1 receptors. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:4 Topics: Animals; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Neurokinin A; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Stereoisomerism; Substance P; Tachykinins	1991
A highly selective NK-2 tachykinin receptor antagonist containing D-tryptophan. European journal of pharmacology, 1990, Jan-03, Volume: 175, Issue:1 Topics: Amino Acid Sequence; Animals; Dogs; In Vitro Techniques; Molecular Sequence Data; Muscle, Smooth, Vascular; Neurokinin A; Peptide Fragments; Rabbits; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Tryptophan	1990
In vivo pharmacology of [beta Ala8]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonist. European journal of pharmacology, 1990, Feb-20, Volume: 177, Issue:1-2 Topics: Anesthesia; Animals; Blood Pressure; Blood Proteins; Bronchi; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Salivation; Urinary Bladder	1990
Neurokinin A-(4-10): a potent bronchospastic agent virtually devoid of sialologic properties in anaesthetized guinea-pigs. European journal of pharmacology, 1988, Apr-13, Volume: 148, Issue:3 Topics: Anesthesia; Animals; Bronchial Spasm; Guinea Pigs; Male; Neurokinin A; Neuropeptides; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Salivation; Substance P; Trachea	1988
Characterization of the peripheral action of neurokinins and neurokinin receptor selective agonists on the rat cardiovascular system. Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:5 Topics: Animals; Cardiovascular System; Female; Injections, Intravenous; Male; Neurokinin A; Neurokinin B; Neurons, Afferent; Parasympathetic Nervous System; Peptide Fragments; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Substance P; Sympathetic Nervous System; Tachycardia	1989
Effects of calcitonin gene-related peptide (CGRP), neurokinin A and neurokinin A (4-10) on the mitogenic response of human peripheral blood mononuclear cells. Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:3 Topics: Adult; Calcitonin; Calcitonin Gene-Related Peptide; Female; Humans; In Vitro Techniques; Male; Mitogens; Monocytes; Neurokinin A; Neuropeptides; Peptide Fragments; Phytohemagglutinins; Thymidine; Vasodilator Agents	1989
Dimerization of neurokinin A and B COOH-terminal heptapeptide fragments enhanced the selectivity for tachykinin receptor subtypes. European journal of pharmacology, 1988, Jul-07, Volume: 151, Issue:2 Topics: Amino Acid Sequence; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Protein Conformation; Rats; Receptors, Neurotransmitter; Receptors, Tachykinin; Vas Deferens	1988
A new selective bioassay for tachykinin NK3 receptors based on inositol monophosphate accumulation in the guinea pig ileum. European journal of pharmacology, 1993, Oct-15, Volume: 247, Issue:2 Topics: Animals; Biphenyl Compounds; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Inositol Phosphates; Male; Muscle, Smooth; Neurokinin A; Peptide Fragments; Phosphatidylinositols; Phospholipids; Receptors, Neurokinin-3; Stimulation, Chemical; Substance P; Tachykinins	1993
Use of non-peptide tachykinin receptor antagonists to substantiate the involvement of NK1 and NK2 receptors in a spinal nociceptive reflex in the rat. European journal of pharmacology, 1993, Mar-02, Volume: 232, Issue:2-3 Topics: Animals; Benzamides; Biphenyl Compounds; Hypnotics and Sedatives; Injections, Spinal; Male; Neurokinin A; Nociceptors; Pain Measurement; Pain Threshold; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Reflex; Spinal Cord; Substance P	1993
Selective neurokinin NK1 and NK2 receptor agonists infused in the substantia nigra of the rat increase vacuous chewing. European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3 Topics: Animals; Dose-Response Relationship, Drug; Female; Mastication; Neurokinin A; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Substantia Nigra	1993
Evidence for the presence of a septide-sensitive tachykinin receptor in the circular muscle of the guinea-pig ileum. European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3 Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neurokinin A; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins	1993
Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors. The American review of respiratory disease, 1993, Volume: 148, Issue:4 Pt 1 Topics: Airway Resistance; Animals; Atropine; Benzamides; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P	1993
NK1 and NK2 receptors mediate tachykinin and resiniferatoxin-induced bronchospasm in guinea pigs. The American review of respiratory disease, 1993, Volume: 148, Issue:4 Pt 1 Topics: Animals; Benzamides; Bronchial Spasm; Bronchoconstriction; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tachykinins	1993
Different mechanism of tachykinin NK2 receptor blockade by SR 48968 and MEN 10,627 in the guinea-pig isolated gallbladder and colon. European journal of pharmacology, 1994, Dec-12, Volume: 271, Issue:1 Topics: Amino Acid Sequence; Animals; Benzamides; Binding, Competitive; Carbachol; Colon; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-2	1994
Characterization of the tachykinin neurokinin-2 receptor in the human urinary bladder by means of selective receptor antagonists and peptidase inhibitors. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amino Acid Sequence; Anti-Bacterial Agents; Drug Interactions; Humans; In Vitro Techniques; Middle Aged; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Peptides; Protease Inhibitors; Receptors, Neurokinin-2; Tachykinins; Urinary Bladder	1993
Role of C-terminal amidation on the biological activity of neurokinin A derivatives with agonist and antagonist properties. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1 Topics: Amides; Amino Acid Sequence; Animals; Cricetinae; Endothelium, Vascular; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mesocricetus; Molecular Sequence Data; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin A; Peptide Fragments; Rabbits; Rats; Rats, Wistar; Receptors, Neurotransmitter; Receptors, Tachykinin; Structure-Activity Relationship	1993
Comparative behavioural profile of centrally administered tachykinin NK1, NK2 and NK3 receptor agonists in the guinea-pig. British journal of pharmacology, 1995, Volume: 116, Issue:5 Topics: Animals; Behavior, Animal; Guinea Pigs; Injections, Intraventricular; Male; Motor Activity; Neurokinin A; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P	1995
Binding and functional potency of neurokinin A analogues in the rat fundus: A structure-activity study. Pharmacology, 1999, Volume: 58, Issue:5 Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Cell Membrane; Gastric Fundus; In Vitro Techniques; Linear Models; Male; Neurokinin A; Peptide Fragments; Radioligand Assay; Rats; Rats, Wistar; Sequence Homology, Amino Acid; Structure-Activity Relationship	1999
Regional differences in signalling transduction pathways among smooth muscle cells from rabbit colon. Cellular signalling, 2000, Volume: 12, Issue:9-10 Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Signaling; Colon; Cyclic AMP; Cyclic GMP; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Peptide Fragments; Rabbits; Tachykinins; Vasoactive Intestinal Peptide	2000
Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs. Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 90, Issue:2 Topics: Administration, Inhalation; Airway Resistance; Animals; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Guinea Pigs; Histamine; Leukocyte Count; Lung; Male; Methacholine Chloride; Neurokinin A; Ovalbumin; Peptide Fragments; Smoking; Substance P; Wakefulness	2001
Nepadutant pharmacokinetics and dose-effect relationships as tachykinin NK2 receptor antagonist are altered by intestinal inflammation in rodent models. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:1 Topics: Acetates; Animals; Antidiarrheals; Biological Availability; Castor Oil; Cathartics; Colon; Dose-Response Relationship, Drug; Enteritis; Gastrointestinal Motility; In Vitro Techniques; Male; Mice; Muscle, Smooth; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Urinary Bladder	2001
Structure-activity relationship of neurokinin A(4-10) at the human tachykinin NK(2) receptor: the effect of amino acid substitutions on receptor affinity and function. Biochemical pharmacology, 2002, Jun-15, Volume: 63, Issue:12 Topics: Amino Acid Substitution; Analysis of Variance; Humans; Jejunum; Neurokinin A; Peptide Fragments; Radioligand Assay; Receptors, Neurokinin-2; Statistics as Topic; Structure-Activity Relationship; Trachea	2002
Human tachykinin NK2 receptor: a comparative study of the colon and urinary bladder. Clinical and experimental pharmacology & physiology, 2003, Volume: 30, Issue:9 Topics: Aged; Aged, 80 and over; Benzamides; Colon; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neurokinin A; Peptide Fragments; Piperidines; Protein Binding; Receptors, Neurokinin-2; Urinary Bladder	2003