netropsin and lexitropsin

netropsin has been researched along with lexitropsin in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (17.91)	18.7374
1990's	35 (52.24)	18.2507
2000's	17 (25.37)	29.6817
2010's	3 (4.48)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lown, JW	3
Joseph, T; Kumar, S; Lown, JW; Pon, RT; Singh, MP	1
Lown, JW; Wang, W	1
Chen, FX; Church, KM; Gold, B; Wurdeman, RL; Zhang, Y	2
Feng, W; Lown, JW; Mazurek, P; Sapse, AM; Shukla, K	1
Dickerson, RE; Kopka, ML; Larsen, TA	1
Lown, JW; Rao, KE; Shea, RG; Yadagiri, B	1
Dabrowiak, JC; Goodisman, J; Kissinger, K	1
Jaseja, M; Kumar, S; Lown, JW; Pon, RT; Sapse, AM; Yadagiri, B; Zimmermann, J	1
Burckhardt, G; Krowicki, K; Lown, JW; Luck, G; Störl, J; Zimmer, C	1
Pullman, B; Randrianarivelo, M; Zakrzewska, K	1
Krowicki, K; Lee, M; Lown, JW; Pon, RT; Shea, RG	1
Dabrowiak, JC; Kissinger, K; Krowicki, K; Lown, JW	1
Hartley, JA; Krowicki, K; Lee, M; Lown, JW; Pon, RT	1
Chang, DK; Hartley, JA; Krowicki, K; Lee, M; Lown, JW; Pon, RT	1
Borer, PN; LaPlante, SR; Levy, GC; Wang, S	1
Lavery, R; Pullman, B; Zakrzewska, K	1
Krowicki, K; Lee, M; Lown, JW; Pon, RT	1
Coulter, DM; Krowicki, K; Lee, M; Lown, JW; Pon, RT	1
Borodulin, VB; Gurskiĭ, GV; Zasedatelev, AS	1
Bordenick, N; Hartley, JA; Lee, M; Webber, J; Wyatt, MD	1
Chen, YH; Lown, JW	1
Bailly, C; Colson, P; Helbecque, N; Hénichart, JP; Houssier, C; Houssin, R; Plouvier, B	1
Lown, JW; Reinert, KE; Stutter, E; Zimmer, C	1
Gupta, R; Lown, JW; Xie, G	1
Bailly, C; Colson, P; Gosselin, G; Hénichart, JP; Houssier, C; Imbach, JL; Lown, JW; Mrani, D; Périgaud, C; Rao, KE	1
Guo, D; Gupta, R; Lown, JW	1
Burckhardt, G; Lown, JW; Luck, G; Störl, K; Zimmer, C	1
Chen, FX; Gold, B; Mehta, P; Zhang, Y	1
Dickerson, RE; Goodsell, DS; Kopka, ML; Lown, JW; Ng, HL	1
al-Said, NH; Gupta, R; Lown, JW; Oreski, B	1
Brazil-Zison, M; Dickerson, RE; Filipowsky, ME; Kopka, ML; Lown, JW	1
al-Said, NH; Lown, JW; Sternbach, DL; Zhao, R	1
Chen, YH; Lown, JW; Yang, Y	1
Gupta, R; Liu, J; Lown, JW; Xie, G	1
Babkina, IN; Baklanov, MM; Gorbunov, IuA; Lokhov, SG; Riabinin, VA; Sandakhchiev, LS; Siniakov, AN	1
Allalunis-Turner, MJ; Cubitt, SA; Lown, JW; Miller, GG; Soderlind, KJ; Xie, Y	1
Dickerson, RE; Goodsell, DS; Landaw, EM; Walker, WL	1
Dickerson, RE; Goodsell, DS; Kopka, ML; Walker, WL	1
Gallagher, K; Sharp, K	1
Lown, JW; Mazumder, A; Neamati, N; Owen, JM; Pommier, Y; Sunder, S; Tandon, M	1
Goodsell, DS; Kopka, ML; Walker, WL	1
Abbondandolo, A; Aprile, A; Campomenosi, P; Chen, FX; Fronza, G; Gold, B; Inga, A; Menichini, P; Monti, P; Ottaggio, L; Viaggi, S	1
Bartulewicz, D; Markowska, A; Pućkowska, A; Rózański, A; Zwierz, K	1
Balduzzi, A; Bonmassar, E; Dande, P; Gold, B; Graziani, G; Lacal, PM; Levati, L; Madaio, R; Portarena, I; Tentori, L; Turriziani, M; Vernole, P	1
Fishleigh, RV; Fox, KR; Khalaf, AI; Pitt, AR; Scobie, M; Suckling, CJ; Urwin, J; Waigh, RD; Young, SC	1
Cui, W; Gmeiner, WH; Lown, JW; Marky, LA; Sharma, S; Soto, AM	1
Lown, JW; Reddy, BS; Sharma, SK	1
Goodsell, DS	1
Herdewijn, P; Zhang, Z	1
Denny, WA	1
Markowska, A; Rózański, A	1
Bailly, C; Boykin, DW; Carrasco, C; Kumar, A; Stephens, CE; Wang, L; Wilson, WD	1
Czuchajowski, L; Domingues, MR; Domingues, P; Ferrer-Correia, AJ; Gajewski, M	1
Arrowsmith, J; Clark, AS; Jennings, SA; Stevens, MF	1
Anthony, NG; Fox, KR; Johnston, BF; Khalaf, AI; Mackay, SP; McGroarty, IS; Parkinson, JA; Skellern, GG; Suckling, CJ; Waigh, RD	1
Anthony, NG; Johnston, BF; Khalaf, AI; MacKay, SP; Parkinson, JA; Suckling, CJ; Waigh, RD	1
Anthony, NG; Drummond, AJ; Ebrahimabadi, AH; Khalaf, AI; Mackay, SP; Suckling, CJ; Waigh, RD	1
Baraldi, PG; Borgatti, M; Carrion, MD; Gambari, R; Heilmann, J; Iaconinoto, MA; Romagnoli, R; Tabrizi, MA	1
Anthony, NG; Breen, D; Clarke, J; Donoghue, G; Drummond, AJ; Ellis, EM; Gemmell, CG; Helesbeux, JJ; Hunter, IS; Khalaf, AI; Mackay, SP; Parkinson, JA; Suckling, CJ; Waigh, RD	1
Crawford, RL; Fusco, W; Han, X; Li, C; Mosher, MD; Natale, NR; Paszczynski, A; Rider, KC; Zhou, P	1
Hibbs, DE; Lo, AT; Rutledge, PJ; Salam, NK; Todd, MH	1
Aldini, G; Colombo, M; Colombo, N; D'Alessio, R; Malyszko, J; Riccardi Sirtori, F; Vistoli, G	1
Ahuja, R; Alniss, HY; Mishra, YK; Panda, PK; Parkinson, JA; Semreen, MH; Witzel, II	1

Reviews

6 review(s) available for netropsin and lexitropsin

Article	Year
Lexitropsins in antiviral drug development. Antiviral research, 1992, Volume: 17, Issue:3 Topics: Antineoplastic Agents; Antiviral Agents; Base Sequence; DNA; Molecular Sequence Data; Netropsin; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	1992
DNA recognition by lexitropsins, minor groove binding agents. Journal of molecular recognition : JMR, 1994, Volume: 7, Issue:2 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Base Sequence; Binding Sites; Distamycins; DNA; Drug Design; Electrochemistry; Humans; Ligands; Models, Biological; Molecular Sequence Data; Molecular Structure; Netropsin; Nucleic Acid Conformation	1994
Progress in the design of DNA sequence-specific lexitropsins. Biopolymers, 1997, Volume: 44, Issue:4 Topics: Antineoplastic Agents; Antiviral Agents; Base Sequence; Binding Sites; DNA; Drug Design; Models, Molecular; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protein Conformation	1997
Recent developments in sequence selective minor groove DNA effectors. Current medicinal chemistry, 2001, Volume: 8, Issue:5 Topics: Animals; Anthraquinones; Benzimidazoles; Bisbenzimidazole; Bleomycin; Chemistry, Pharmaceutical; Cross-Linking Reagents; Distamycins; DNA; Drug Design; Duocarmycins; Humans; Indoles; Leucomycins; Ligands; Netropsin; Urea	2001
Sequence recognition of DNA by lexitropsins. Current medicinal chemistry, 2001, Volume: 8, Issue:5 Topics: Base Pairing; Crystallography, X-Ray; Distamycins; DNA; Drug Design; Models, Chemical; Models, Molecular; Netropsin	2001
DNA minor groove alkylating agents. Current medicinal chemistry, 2001, Volume: 8, Issue:5 Topics: Alkylating Agents; Animals; Anthramycin; Antibiotics, Antineoplastic; Benzofurans; Bisbenzimidazole; Chlorambucil; Cyclohexanecarboxylic Acids; Cyclohexenes; Distamycins; DNA; Duocarmycins; Humans; Indoles; Netropsin; Nitrogen Mustard Compounds; Pyrroles; Structure-Activity Relationship	2001

Other Studies

61 other study(ies) available for netropsin and lexitropsin

Article	Year
A 1H-NMR study of the DNA binding characteristics of thioformyldistamycin, an amide isosteric lexitropsin. Biochemistry, 1992, Jul-21, Volume: 31, Issue:28 Topics: Base Sequence; Computer Simulation; Distamycins; DNA; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Netropsin; Oligodeoxyribonucleotides	1992
Anti-HIV-I activity of linked lexitropsins. Journal of medicinal chemistry, 1992, Jul-24, Volume: 35, Issue:15 Topics: Antiviral Agents; Cells, Cultured; DNA, Viral; Drug Design; HIV-1; Moloney murine leukemia virus; Netropsin; Structure-Activity Relationship; Viral Plaque Assay	1992
Control over the sequence specificity of DNA alkylation: syntheses and reactions with 32P-end-labelled DNA of N-alkyl-N-nitrosoureas linked to minor groove binding lexitropsins. IARC scientific publications, 1991, Issue:105 Topics: Alkylation; Antineoplastic Agents; Base Sequence; DNA; Molecular Sequence Data; Netropsin; Nitrosourea Compounds; Phosphorus Radioisotopes	1991
The binding of prototype lexitropsins to the minor groove of DNA: quantum chemical studies. Journal of biomolecular structure & dynamics, 1991, Volume: 9, Issue:2 Topics: Base Sequence; DNA; Hydrogen Bonding; Molecular Sequence Data; Molecular Structure; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Quantum Theory	1991
Crystal structure analysis of the B-DNA dodecamer CGTGAATTCACG. Biochemistry, 1991, May-07, Volume: 30, Issue:18 Topics: Base Sequence; Binding Sites; DNA; Fourier Analysis; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Oligonucleotides; Stereoisomerism; Water; X-Ray Diffraction	1991
Molecular recognition between oligopeptides and nucleic acids: DNA sequence specificity and binding properties of thiazole-lexitropsins incorporating the concepts of base site acceptance and avoidance. Anti-cancer drug design, 1990, Volume: 5, Issue:1 Topics: Base Sequence; Binding Sites; DNA; Drug Interactions; Guanidines; In Vitro Techniques; Ligands; Molecular Sequence Data; Netropsin; Nucleic Acid Denaturation; Protein Binding; Restriction Mapping; Structure-Activity Relationship; Thiazoles	1990
N-(2-chloroethyl)-N-nitrosoureas covalently bound to nonionic and monocationic lexitropsin dipeptides. Synthesis, DNA affinity binding characteristics, and reactions with 32P-end-labeled DNA. Biochemistry, 1990, Jul-24, Volume: 29, Issue:29 Topics: Alkylation; Base Sequence; Binding Sites; Cations; Distamycins; DNA; DNA Restriction Enzymes; Ethylnitrosourea; Guanidines; Guanine; Molecular Sequence Data; Molecular Structure; Netropsin	1990
Thermodynamic data from drug-DNA footprinting experiments. Biochemistry, 1990, Jul-03, Volume: 29, Issue:26 Topics: Base Sequence; Binding Sites; Deoxyribonuclease I; DNA, Bacterial; Hydrogen Bonding; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Nucleotide Mapping; Thermodynamics	1990
Molecular recognition and binding of a GC site-avoiding thiazole-lexitropsin to the decadeoxyribonucleotide d-[CGCAATTGCG]2: 1H-NMR evidence for thiazole intercalation. Journal of biomolecular structure & dynamics, 1990, Volume: 8, Issue:1 Topics: Base Composition; Base Sequence; Binding Sites; DNA; Hydrogen; Intercalating Agents; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Thermodynamics; Thiazoles	1990
Variation of DNA sequence specificity of DNA-oligopeptide binding ligands related to netropsin: imidazole-containing lexitropsins. Biochimica et biophysica acta, 1989, Sep-21, Volume: 1009, Issue:1 Topics: Base Composition; Binding Sites; Circular Dichroism; DNA; Guanidines; Imidazoles; Netropsin; Poly dA-dT; Polydeoxyribonucleotides; Structure-Activity Relationship	1989
Theoretical modeling of DNA-monocationic lexitropsin complexation: influence of ligand binding on DNA curvature. Journal of biomolecular structure & dynamics, 1989, Volume: 6, Issue:4 Topics: Computer Simulation; DNA; DNA-Binding Proteins; Models, Molecular; Netropsin; Nucleic Acid Conformation; Thermodynamics	1989
Molecular recognition between oligopeptides and nucleic acids. Specificity of binding of a monocationic bis-furan lexitropsin to DNA deduced from footprinting and 1H NMR studies. Journal of molecular recognition : JMR, 1989, Volume: 2, Issue:2 Topics: Base Sequence; Binding Sites; Densitometry; DNA; Guanidines; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligopeptides; Protons	1989
Molecular recognition between oligopeptides and nucleic acids. Monocationic imidazole lexitropsins that display enhanced GC sequence dependent DNA binding. Biochemistry, 1987, Sep-08, Volume: 26, Issue:18 Topics: Base Sequence; Deoxyribonuclease I; DNA; Guanidines; Imidazoles; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Netropsin; Oligopeptides; Structure-Activity Relationship	1987
Sequence specific molecular recognition by a monocationic lexitropsin of the decadeoxyribonucleotide d-[CATGGCCATG]2: structural and dynamic aspects deduced from high field 1H-NMR studies. Nucleic acids research, 1988, Jan-25, Volume: 16, Issue:2 Topics: Computer Simulation; DNA-Binding Proteins; Guanidines; Hydrogen Bonding; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Chemical; Motion; Netropsin; Oligodeoxyribonucleotides; Protein Binding	1988
Structural and dynamic aspects of binding of a prototype lexitropsin to the decadeoxyribonucleotide d(CGCAATTGCG)2 deduced from high-resolution 1H NMR Studies. Biochemistry, 1988, Jan-12, Volume: 27, Issue:1 Topics: Base Sequence; DNA; Guanidines; Hydrogen; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protein Binding; Protein Conformation	1988
Analysis of DNA and DNA-lexitropsin interaction using multinuclear NMR and molecular dynamics. Biochemical pharmacology, 1988, May-01, Volume: 37, Issue:9 Topics: DNA; Guanidines; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Conformation; Netropsin; Thermodynamics	1988
Lexitropsins: rational design of DNA sequence reading agents as novel anti-cancer agents and potential cellular probes. Anti-cancer drug design, 1988, Volume: 3, Issue:1 Topics: Antineoplastic Agents; Base Sequence; Biological Transport; Gene Expression Regulation; Guanidines; Netropsin; Nucleic Acid Conformation; Protein Binding; Structure-Activity Relationship	1988
A theoretical study of the sequence specificity in binding of lexitropsins to B-DNA. Journal of biomolecular structure & dynamics, 1987, Volume: 4, Issue:5 Topics: Base Sequence; Chemical Phenomena; Chemistry, Physical; DNA; Guanidines; Hydrogen Bonding; Imidazoles; Models, Molecular; Netropsin; Poly dA-dT; Polydeoxyribonucleotides	1987
Structural and dynamic aspects of the sequence specific binding of netropsin and its bis-imidazole analogue on the decadeoxyribonucleotide d-[CGCAATTGCG]2. Journal of biomolecular structure & dynamics, 1988, Volume: 5, Issue:4 Topics: Base Sequence; DNA-Binding Proteins; Guanidines; Kinetics; Magnetic Resonance Spectroscopy; Netropsin; Oligodeoxyribonucleotides; Protein Binding; Repetitive Sequences, Nucleic Acid	1988
Sequence specific molecular recognition and binding of a monocationic bis-imidazole lexitropsin to the decadeoxyribonucleotide d-[(GATCCGTATG).(CATACGGATC)]: structural and dynamic aspects of intermolecular exchange studied by 1H-NMR. Journal of biomolecular structure & dynamics, 1988, Volume: 5, Issue:5 Topics: Base Sequence; Binding Sites; Guanidines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides	1988
[Interaction of lexitropsin with DNA: negative result of the attempt to detect complex AT/GC-specific binding]. Doklady Akademii nauk SSSR, 1987, Volume: 294, Issue:5 Topics: Base Sequence; Binding Sites; Chemical Phenomena; Chemistry; DNA; Guanidines; Kinetics; Ligands; Netropsin	1987
Novel cytotoxic DNA sequence and minor groove targeted photosensitizers: conjugates of pyrene and netropsin analogues. Bioorganic & medicinal chemistry, 1995, Volume: 3, Issue:6 Topics: Antineoplastic Agents; Bacteriophage T4; Circular Dichroism; DNA; DNA Damage; DNA, Viral; Humans; Netropsin; Photosensitizing Agents; Pyrenes; Structure-Activity Relationship; Thymus Gland; Tumor Cells, Cultured; Ultraviolet Rays	1995
DNA minor groove binding of cross-linked lexitropsins: experimental conditions required to observe the covalently linked WPPW (groove wall-peptide-peptide-groove wall) motif. Biophysical journal, 1995, Volume: 68, Issue:5 Topics: Antineoplastic Agents; Antiviral Agents; Binding Sites; Cross-Linking Reagents; DNA; Imidazoles; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Models, Theoretical; Netropsin; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Protein Binding; Protein Conformation	1995
Influence of the methyl substituents of a thiazole-containing lexitropsin on the mode of binding to DNA. Anti-cancer drug design, 1995, Volume: 10, Issue:2 Topics: Animals; Antineoplastic Agents; Binding Sites; Cattle; DNA; Intercalating Agents; Netropsin; Spectrum Analysis; Thiazoles; Viscosity	1995
DNA interaction of the imidazole-containing lexitropsin ImPy: titration viscometric study in comparison to netropsin. Journal of biomolecular structure & dynamics, 1995, Volume: 12, Issue:4 Topics: Animals; Binding Sites; Cattle; DNA; Imidazoles; Ligands; Molecular Structure; Netropsin; Titrimetry; Viscosity	1995
Hybrid molecules containing propargylic sulfones and DNA minor groove-binding lexitropsins: synthesis, sequence specificity of reaction with DNA and biological evaluation. Gene, 1994, Nov-04, Volume: 149, Issue:1 Topics: 1-Propanol; Alkynes; Antineoplastic Agents; Base Sequence; Binding Sites; DNA; Drug Screening Assays, Antitumor; Hot Temperature; Humans; Kinetics; Molecular Sequence Data; Molecular Structure; Netropsin; Oligopeptides; Propanols; Sulfones; Tumor Cells, Cultured	1994
Psoralen--lexitropsin hybrids: DNA sequence selectivity of photoinduced cross-linking from MPE footprinting and exonuclease III stop assay, and mode of binding from electric linear dichroism. Anti-cancer drug design, 1994, Volume: 9, Issue:3 Topics: Antineoplastic Agents; Base Sequence; DNA; Edetic Acid; Exodeoxyribonucleases; Furocoumarins; Molecular Sequence Data; Netropsin	1994
DNA sequence-selective binding of head-to-tail linked bis-lexitropsins: relation of phasing to cytotoxic potency. Anti-cancer drug design, 1993, Volume: 8, Issue:5 Topics: Antineoplastic Agents; Base Sequence; DNA; Drug Screening Assays, Antitumor; Humans; Molecular Sequence Data; Netropsin; Protein Binding; Structure-Activity Relationship; Tumor Cells, Cultured	1993
Binding to DNA of selected lexitropsins and effects on prokaryotic topoisomerase activity. Biochimica et biophysica acta, 1993, Jun-25, Volume: 1173, Issue:3 Topics: Animals; Circular Dichroism; Distamycins; DNA; DNA Topoisomerases, Type I; Netropsin; Temperature; Topoisomerase II Inhibitors	1993
Groove- and sequence-selective alkylation of DNA by sulfonate esters tethered to lexitropsins. Biochemistry, 1993, Aug-10, Volume: 32, Issue:31 Topics: Alkanesulfonates; Alkylating Agents; Base Sequence; DNA; Models, Molecular; Molecular Sequence Data; Netropsin	1993
Structure of a dicationic monoimidazole lexitropsin bound to DNA. Biochemistry, 1995, Dec-26, Volume: 34, Issue:51 Topics: Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Cations; Crystallography, X-Ray; DNA; DNA Adducts; Electrochemistry; Hydrogen Bonding; Imidazoles; Models, Molecular; Molecular Sequence Data; Molecular Structure; Netropsin; Nucleic Acid Conformation	1995
Design, synthesis and topoisomerase II inhibition activity of 4'-demethylepipodophyllotoxin-lexitropsin conjugates. Anti-cancer drug design, 1996, Volume: 11, Issue:4 Topics: Antineoplastic Agents; Base Sequence; Catalysis; Cell Survival; DNA Topoisomerases, Type II; DNA, Recombinant; Drug Design; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Netropsin; Podophyllotoxin; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1996
Linked lexitropsins and the in vitro inhibition of HIV-1 reverse transcriptase RNA-directed DNA polymerization: a novel induced-fit of 3,5 m-pyridyl bisdistamycin to enzyme-associated template-primer. Biochemistry, 1996, Dec-03, Volume: 35, Issue:48 Topics: Antiviral Agents; Bisbenzimidazole; Diminazene; Distamycins; DNA Polymerase I; DNA Primers; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; Indoles; Kinetics; Models, Molecular; Netropsin; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides	1996
Camptothecin and minor-groove binder hybrid molecules: synthesis, inhibition of topoisomerase I, and anticancer cytotoxicity in vitro. Journal of medicinal chemistry, 1997, Jan-17, Volume: 40, Issue:2 Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; HT29 Cells; Humans; KB Cells; Netropsin; Ovarian Neoplasms; Topoisomerase I Inhibitors; Tumor Cells, Cultured	1997
Optimization of cross-linked lexitropsins. Journal of biomolecular structure & dynamics, 1996, Volume: 14, Issue:3 Topics: Circular Dichroism; Cross-Linking Reagents; Ethidium; Fluorometry; Models, Chemical; Models, Molecular; Netropsin; Oligonucleotides; Titrimetry	1996
Novel DNA-directed alkylating agents consisting of naphthalimide, nitrogen mustard and lexitropsin moieties: synthesis, DNA sequence specificity and biological evaluation. Anti-cancer drug design, 1996, Volume: 11, Issue:8 Topics: 1-Naphthylamine; Antineoplastic Agents, Alkylating; Base Sequence; Binding Sites; DNA; Drug Screening Assays, Antitumor; Humans; Imides; Mechlorethamine; Molecular Sequence Data; Netropsin; Tumor Cells, Cultured	1996
[Conjugates of oligodeoxyribonucleotides with lexitropsins, forming a DNA-ligand complex with a 1:2 ratio]. Doklady Akademii nauk, 1997, Volume: 352, Issue:2 Topics: Antiviral Agents; DNA; Netropsin; Polymerase Chain Reaction; Temperature	1997
Enediyne-lexitropsin DNA-targeted anticancer agents. Physicochemical and cytotoxic properties in human neoplastic cells in vitro, and intracellular distribution. Anti-cancer drug design, 1997, Volume: 12, Issue:3 Topics: Antibiotics, Antineoplastic; Cell Line; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Netropsin; Tissue Distribution; Tumor Cells, Cultured	1997
Estimation of the DNA sequence discriminatory ability of hairpin-linked lexitropsins. Proceedings of the National Academy of Sciences of the United States of America, 1997, May-27, Volume: 94, Issue:11 Topics: Antineoplastic Agents; Base Sequence; DNA; Models, Chemical; Netropsin; Oligodeoxyribonucleotides; Reproducibility of Results; Structure-Activity Relationship; Thermodynamics	1997
Design of stapled DNA-minor-groove-binding molecules with a mutable atom simulated annealing method. Journal of computer-aided molecular design, 1997, Volume: 11, Issue:6 Topics: Base Sequence; Binding Sites; Distamycins; DNA; Entropy; Hydrogen Bonding; Hydroxides; Netropsin; Structure-Activity Relationship	1997
Electrostatic contributions to heat capacity changes of DNA-ligand binding. Biophysical journal, 1998, Volume: 75, Issue:2 Topics: Antineoplastic Agents; Binding Sites; Bisbenzimidazole; DNA; DNA-Binding Proteins; Hot Temperature; Indoles; Intercalating Agents; Ligands; Models, Chemical; Netropsin; Repressor Proteins; Static Electricity; Thermodynamics; Viral Proteins; Viral Regulatory and Accessory Proteins	1998
Highly potent synthetic polyamides, bisdistamycins, and lexitropsins as inhibitors of human immunodeficiency virus type 1 integrase. Molecular pharmacology, 1998, Volume: 54, Issue:2 Topics: Anti-HIV Agents; Base Sequence; Cells, Cultured; Distamycins; DNA Footprinting; HIV Integrase; HIV Integrase Inhibitors; Humans; Molecular Sequence Data; Netropsin; Nylons; Repetitive Sequences, Nucleic Acid; Sequence Alignment; Structure-Activity Relationship	1998
N-(2-chloroethyl)-N-nitrosourea tethered to lexitropsin induces minor groove lesions at the p53 cDNA that are more cytotoxic than mutagenic. Cancer research, 1999, Feb-01, Volume: 59, Issue:3 Topics: Alkylation; Antineoplastic Agents; Base Sequence; DNA, Complementary; Ethylnitrosourea; Genes, p53; Humans; Molecular Sequence Data; Mutagens; Netropsin; Structure-Activity Relationship; Transfection	1999
Synthetic analogues of netropsin and distamycin. V. Synthesis of a carbocyclic bis-lexitropsin as potential DNA cleaving agent. Roczniki Akademii Medycznej w Bialymstoku (1995), 1999, Volume: 44 Topics: Antineoplastic Agents; Antiviral Agents; Cell Division; Distamycins; Humans; Netropsin	1999
Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemic cells. Leukemia, 2000, Volume: 14, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Chromosome Aberrations; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation; HT29 Cells; Humans; Jurkat Cells; Mutagens; Netropsin; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Suppressor Protein p53; X-ray Repair Cross Complementing Protein 1	2000
DNA binding, solubility, and partitioning characteristics of extended lexitropsins. Journal of medicinal chemistry, 2000, Aug-24, Volume: 43, Issue:17 Topics: DNA; DNA Footprinting; Electrophoresis, Polyacrylamide Gel; Hydrogen Bonding; Hydrogen-Ion Concentration; Ligands; Netropsin; Pyrroles; Solubility	2000
Shape-selective binding of geometrically-constrained bis-distamycins to a DNA duplex and a model Okazaki fragment of identical sequence. Nucleosides, nucleotides & nucleic acids, 2000, Volume: 19, Issue:8 Topics: Base Sequence; Calorimetry, Differential Scanning; Distamycins; DNA; Ligands; Molecular Structure; Netropsin; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Temperature; Transcription, Genetic	2000
Selection of an unnatural peptide library for dsDNA binding. Current medicinal chemistry, 2001, Volume: 8, Issue:5 Topics: Amino Acids; Amsacrine; Binding Sites; Chemistry, Pharmaceutical; Combinatorial Chemistry Techniques; DNA; Drug Design; Humans; Models, Molecular; Netropsin; Peptide Library	2001
Synthetic analogues of netropsin and distamycin. VI. Synthesis of carbocyclic lexitropsins containing a bioreductive element. Acta poloniae pharmaceutica, 2000, Volume: 57 Suppl Topics: Alkylation; Antineoplastic Agents; Cell Hypoxia; Distamycins; DNA, Neoplasm; Netropsin; Oxidation-Reduction	2000
Evaluation of the influence of compound structure on stacked-dimer formation in the DNA minor groove. Biochemistry, 2001, Feb-27, Volume: 40, Issue:8 Topics: Amidines; Base Pairing; Benzimidazoles; Binding Sites; Carbazoles; Cations; Circular Dichroism; DNA; DNA Footprinting; Furans; Guanidine; Netropsin; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Pyrimidine Dimers; Spectrophotometry, Ultraviolet; Surface Plasmon Resonance	2001
Electrospray tandem mass spectrometry of lexitropsins. Rapid communications in mass spectrometry : RCM, 2001, Volume: 15, Issue:12 Topics: Antineoplastic Agents; Antiviral Agents; Netropsin; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization	2001
Antitumor imidazotetrazines. 41. Conjugation of the antitumor agents mitozolomide and temozolomide to peptides and lexitropsins bearing DNA major and minor groove-binding structural motifs. Journal of medicinal chemistry, 2002, Dec-05, Volume: 45, Issue:25 Topics: Amino Acids; Animals; Antineoplastic Agents; Cell Line; Dacarbazine; DNA; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Mice; Models, Molecular; Netropsin; Nitrogen Mustard Compounds; Peptides; Temozolomide; Tumor Cells, Cultured	2002
DNA binding of a short lexitropsin. Bioorganic & medicinal chemistry letters, 2004, Mar-08, Volume: 14, Issue:5 Topics: Binding Sites; DNA; DNA-Binding Proteins; Netropsin; Protein Binding	2004
Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole. Journal of the American Chemical Society, 2004, Sep-15, Volume: 126, Issue:36 Topics: DNA; Hydrogen; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Netropsin; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Pyrroles; Thiazoles	2004
Synthesis and antimicrobial activity of some netropsin analogues. Organic & biomolecular chemistry, 2004, Nov-07, Volume: 2, Issue:21 Topics: Anti-Infective Agents; Bacteria; Microbial Sensitivity Tests; Models, Molecular; Netropsin	2004
Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates. European journal of medicinal chemistry, 2005, Volume: 40, Issue:11 Topics: Animals; Antineoplastic Agents, Alkylating; Benzofurans; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Imidazoles; Mice; Molecular Structure; Netropsin; Pyrazoles; Pyrroles; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured	2005
Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24 Topics: Alkenes; Amides; Amidines; Animals; Anti-Bacterial Agents; Antifungal Agents; Aspergillus niger; Candida albicans; Cell Line; Enterococcus faecalis; Hydrophobic and Hydrophilic Interactions; Intercalating Agents; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium fortuitum; Netropsin; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism	2007
Design, synthesis and biological evaluation of a novel class of anticancer agents: anthracenylisoxazole lexitropsin conjugates. Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4 Topics: Anthracenes; Antineoplastic Agents; Azoles; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Netropsin; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship	2009
Polyamide-scorpion cyclam lexitropsins selectively bind AT-rich DNA independently of the nature of the coordinated metal. PloS one, 2011, May-09, Volume: 6, Issue:5 Topics: AT Rich Sequence; Calorimetry; DNA; GC Rich Sequence; Heterocyclic Compounds; Metals; Netropsin; Nylons; Thermodynamics	2011
Molecular recognition of T:G mismatched base pairs in DNA as studied by electrospray ionization mass spectrometry. ChemMedChem, 2012, Volume: 7, Issue:6 Topics: Base Pair Mismatch; DNA; Guanine; Netropsin; Spectrometry, Mass, Electrospray Ionization; Thymine	2012
Investigation of the Factors That Dictate the Preferred Orientation of Lexitropsins in the Minor Groove of DNA. Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22 Topics: Binding Sites; Dimerization; DNA; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Dynamics Simulation; Molecular Weight; Netropsin; Nucleic Acid Conformation; Thiazoles	2019