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neplanocin a and s-adenosylhomocysteine

neplanocin a has been researched along with s-adenosylhomocysteine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's4 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borchardt, RT; Kramer, DL; Porter, CW; Sufrin, JR1
Borchardt, RT; Borcherding, DR; Hasobe, M; Keller, BT; Mckee, JG1
Borchardt, RT; Hasobe, M; McKee, JG1
Borchardt, RT; Decedue, CJ; Fisher, EW; Keller, BT1
Glazer, RI; Haines, DR; Knode, MC; Marquez, VE; Tseng, CK1
Borchardt, RT; Keller, BT1
Linder, M; Scholtissek, C; Woyciniuk, P1
Bu, G; Oxenrider, KA; Sitz, TO1
Tsiftsoglou, AS; Vizirianakis, IS1
Converso, A; Fraley, ME; Garbaccio, RM; Hartingh, T; Hartman, GD; Huang, SY; Majercak, JM; McCampbell, A; Na, SJ; Ray, WJ; Savage, MJ; White, R; Wolffe, C; Yeh, S; Yu, Y; Zhang, R1

Other Studies

10 other study(ies) available for neplanocin a and s-adenosylhomocysteine

ArticleYear
Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
    Cancer research, 1990, Jul-01, Volume: 50, Issue:13

    Topics: Adenosine; Animals; Cell Division; DNA, Neoplasm; Homocysteine; Leukemia L1210; Methylation; Polyamines; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors

1990
Effects of 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine on the metabolism of S-adenosylhomocysteine in mouse L929 cells.
    Molecular pharmacology, 1988, Volume: 33, Issue:6

    Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; Animals; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Homocysteine; Hydrolases; Mice; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship

1988
Relationship between intracellular concentration of S-adenosylhomocysteine and inhibition of vaccinia virus replication and inhibition of murine L-929 cell growth.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Antibiotics, Antineoplastic; Cell Division; Chromatography, High Pressure Liquid; Homocysteine; Hydrolases; L Cells; Methylation; Mice; S-Adenosylhomocysteine; Time Factors; Vaccinia virus; Virus Replication

1989
Neplanocin A inhibition of S-adenosylhomocysteine hydrolase in Alcaligenes faecalis has no effect on growth of the microorganism.
    The Journal of antibiotics, 1987, Volume: 40, Issue:6

    Topics: Adenosine; Adenosylhomocysteinase; Alcaligenes; Bacillus subtilis; Hydrolases; N-Glycosyl Hydrolases; S-Adenosylhomocysteine; S-Adenosylmethionine

1987
3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Colonic Neoplasms; Humans; Hydrolases; Kinetics; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylhomocysteine; Uridine

1986
Metabolic conversion of neplanocin A to S-neplanocylmethionine by mouse L 929 cells.
    Biochemical and biophysical research communications, 1984, Apr-16, Volume: 120, Issue:1

    Topics: Adenosine; Animals; Biotransformation; L Cells; Methionine; Methyltransferases; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity

1984
The methyltransferase inhibitor Neplanocin A interferes with influenza virus replication by a mechanism different from that of 3-deazaadenosine.
    Virus research, 1995, Volume: 35, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Drug Synergism; Homocysteine; Hydrolases; Influenza A virus; Methionine; Methyltransferases; RNA Caps; RNA, Viral; S-Adenosylhomocysteine; Tubercidin; Viral Proteins; Virus Replication

1995
Adenosine analogs inhibit the guanine-7-methylation of mRNA cap structures.
    FEBS letters, 1993, Feb-01, Volume: 316, Issue:3

    Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; In Vitro Techniques; Methylation; Methyltransferases; Mice; RNA Caps; S-Adenosylhomocysteine

1993
Induction of murine erythroleukemia cell differentiation is associated with methylation and differential stability of poly(A)+ RNA transcripts.
    Biochimica et biophysica acta, 1996, Jun-05, Volume: 1312, Issue:1

    Topics: Actins; Adenosine; Animals; Cell Differentiation; Cell Division; Cycloleucine; Dimethyl Sulfoxide; Erythrocytes; Erythropoiesis; Globins; Hemoglobins; Kinetics; Leukemia, Erythroblastic, Acute; Methylation; Mice; Neoplasm Proteins; Peroxidases; Peroxiredoxin III; Peroxiredoxins; Proto-Oncogene Proteins c-myc; Ribonucleotides; RNA Caps; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured

1996
Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase.
    Bioorganic & medicinal chemistry letters, 2014, Jun-15, Volume: 24, Issue:12

    Topics: Adenosine; Animals; Brain Chemistry; Drug Design; Enzyme Activation; Enzyme Inhibitors; Homocysteine; Hydrogen Bonding; Hydrolases; Inhibitory Concentration 50; Models, Molecular; Rats; S-Adenosylhomocysteine; Substrate Specificity

2014