Page last updated: 2024-08-25

neplanocin a and cytarabine

neplanocin a has been researched along with cytarabine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corbett, TH; Court, BA; Kessel, D; Phadtare, S; Renis, HE; Zimlicka, J1
Phadtare, S; Zemlicka, J1
Davari, H; Hakimelahi, GH; Hakimelahi, S; Hwu, JR; King, KY; Mei, NW; Moosavi-Movahedi, AA; Wen, YS1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chandra, G; Chang, TS; Choi, S; Jang, JY; Jeong, LS; Kim, G; Lee, SK; Lee, Y; Moon, YW; Mulamoottil, VA; Nayak, A; Noh, M; Oh, K; Sahu, PK; Song, J1
De Clercq, E; Marquez, VE; Murase, J1
Honma, Y; Kanatani, Y; Matsuda, A; Niitsu, N; Shuto, S; Umeda, M; Yamamoto-Yamaguchi, Y1

Other Studies

7 other study(ies) available for neplanocin a and cytarabine

ArticleYear
Unsaturated and carbocyclic nucleoside analogues: synthesis, antitumor, and antiviral activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Friend murine leukemia virus; HIV-1; HIV-2; Humans; Indicators and Reagents; Leukemia L1210; Mice; Molecular Structure; Nucleosides; Rauscher Virus; Structure-Activity Relationship

1991
Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Antibiotics, Antineoplastic; Guanine; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1987
Synthesis and biological evaluation of purine-containing butenolides.
    Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11

    Topics: 4-Butyrolactone; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Furans; Herpesvirus 3, Human; Humans; Hydrolases; Kinetics; Magnetic Resonance Spectroscopy; Mice; Purines; Stereoisomerism; Structure-Activity Relationship; Thymidine Kinase; Tumor Cells, Cultured

2001
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
    Journal of medicinal chemistry, 2015, Jun-25, Volume: 58, Issue:12

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Vero Cells; Virus Diseases; Viruses

2015
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses

1991
Neplanocin A, a potent inhibitor of S-adenosylhomocysteine hydrolase, potentiates granulocytic differentiation of acute promyelocytic leukemia cells induced by all-trans retinoic acid.
    Experimental hematology, 1997, Volume: 25, Issue:12

    Topics: Adenosine; Adenosylhomocysteinase; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Synergism; Enzyme Inhibitors; Granulocytes; Humans; Hydrolases; Leukemia, Promyelocytic, Acute; Leukopoiesis; Tretinoin; Tumor Cells, Cultured

1997