Page last updated: 2024-08-25

neplanocin a and adenine

neplanocin a has been researched along with adenine in 10 studies

*Adenine: A purine base and a fundamental unit of ADENINE NUCLEOTIDES. [MeSH]

*Adenine: A purine base and a fundamental unit of ADENINE NUCLEOTIDES. [MeSH]

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hanai, Y; Maruyama, T; Sato, Y1
Cools, M; de Clercq, E2
De Clercq, E; Kitaoka, S; Konno, T1
Borchardt, RT; Borcherding, DR; Keller, BT; Narayanan, SR; Scholtz, SA1
De Clercq, E; Durbin, RK; Stollar, V1
Borchardt, RT; Borcherding, DR; Hasobe, M; Keller, BT; McKee, JG; Narayanan, S1
Phadtare, S; Zemlicka, J1
Chandra, G; Chang, TS; Choi, S; Jang, JY; Jeong, LS; Kim, G; Lee, SK; Lee, Y; Moon, YW; Mulamoottil, VA; Nayak, A; Noh, M; Oh, K; Sahu, PK; Song, J1
Chen, Q; Liu, C; Schneller, SW1

Other Studies

10 other study(ies) available for neplanocin a and adenine

ArticleYear
Synthesis of methylenecyclobutyl- and cyclobutenyl adenine A, potent antiviral carbocyclic analogues of oxetanocin A.
    Nucleic acids symposium series, 1991, Issue:25

    Topics: Adenine; Adenosine; Antiviral Agents; Molecular Structure

1991
Correlation between the antiviral activity of acyclic and carbocyclic adenosine analogues in murine L929 cells and their inhibitory effect on L929 cells S-adenosylhomocysteine hydrolase.
    Biochemical pharmacology, 1989, Apr-01, Volume: 38, Issue:7

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Fibroblasts; Hydrolases; Kinetics; Mice; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication

1989
Antiviral potency of adenosine analogues: correlation with inhibition of S-adenosylhomocysteine hydrolase.
    Biochemical and biophysical research communications, 1985, May-31, Volume: 129, Issue:1

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Antibiotics, Antineoplastic; Antiviral Agents; Hydrolases; Kinetics; Measles virus; Reoviridae; Tubercidin; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication

1985
Comparative efficacy of broad-spectrum antiviral agents as inhibitors of rotavirus replication in vitro.
    Antiviral research, 1986, Volume: 6, Issue:1

    Topics: Adenine; Adenosine; Amides; Antiviral Agents; Cell Line; Cytidine; Dose-Response Relationship, Drug; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Rotavirus; Tubercidin; Vidarabine; Virus Replication

1986
9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Cattle; Hydrolases; Kinetics; Liver; NAD

1988
SVLM21, a mutant of Sindbis virus able to grow in Aedes albopictus cells in the absence of methionine, shows increased sensitivity to S-adenosylhomocysteine hydrolase inhibitors such as neplanocin A.
    Virology, 1988, Volume: 163, Issue:1

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Aedes; Animals; Antiviral Agents; Cell Line; Genes, Viral; Hydrolases; Methionine; Methyltransferases; Mutation; S-Adenosylmethionine; Sindbis Virus; Tubercidin; Viral Plaque Assay

1988
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 11. Molecular dissections of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antibiotics, Antineoplastic; Antiviral Agents; Cattle; Cell Line; Chemical Phenomena; Chemistry; Hydrolases; Liver; Mice; Vaccinia virus; Virus Replication

1988
Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Antibiotics, Antineoplastic; Guanine; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1987
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
    Journal of medicinal chemistry, 2015, Jun-25, Volume: 58, Issue:12

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Vero Cells; Virus Diseases; Viruses

2015
Enantiomeric 3-deaza-1',6'-isoneplanocin and its 3-bromo analogue: Synthesis by the Ullmann reaction and their antiviral properties.
    Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Antiviral Agents; Cytomegalovirus; Ebolavirus; Humans; Morbillivirus; Norovirus; Nucleosides; Stereoisomerism

2016