neplanocin a has been researched along with 9-(2',3'-dihydroxycyclopent-4'-enyl)adenine in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borchardt, RT; Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Borchardt, RT; Borcherding, DR; Hasobe, M; McKee, JG | 1 |
| Borchardt, RT; Borcherding, DR; Hasobe, M; Keller, BT; Mckee, JG | 1 |
| Balzarini, J; Borchardt, RT; Borcherding, DR; Cools, M; De Clercq, E; Drach, JC; Kitaoka, S; Konno, T; Marquez, VE | 1 |
| Bartlett, WJ; Borchardt, RT; Borcherding, DR; Lee, Y; Wolfe, MS | 1 |
| Borchardt, RT; Borcherding, DR; Keller, BT; Narayanan, SR; Scholtz, SA | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; Matsuda, A; Obara, T; Saito, Y; Shuto, S; Snoeck, R | 1 |
| Ahn, HS; Choi, WJ; Chun, MW; Jeong, LS; Kim, HO; Lee, KM; Moon, HR; Yoo, SJ | 1 |
| Choi, S; Choi, WJ; Heo, YS; Hwang, KY; Jeong, LS; Kim, HO; Lee, HJ; Lee, HW; Lee, KM; Lee, Y; Park, JG; Zhao, LX | 1 |
| Converso, A; Fraley, ME; Garbaccio, RM; Hartingh, T; Hartman, GD; Huang, SY; Majercak, JM; McCampbell, A; Na, SJ; Ray, WJ; Savage, MJ; White, R; Wolffe, C; Yeh, S; Yu, Y; Zhang, R | 1 |
10 other study(ies) available for neplanocin a and 9-(2',3'-dihydroxycyclopent-4'-enyl)adenine
| Article | Year |
|---|---|
Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
Topics: Adenosine; Animals; Cell Division; DNA, Neoplasm; Homocysteine; Leukemia L1210; Methylation; Polyamines; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1990 |
9-(trans-2',trans-3'-Dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine: analogs of neplanocin A which retain potent antiviral activity but exhibit reduced cytotoxicity.
Topics: Adenosine; Antiviral Agents; Cell Survival; DNA; RNA; Structure-Activity Relationship | 1987 |
Effects of 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine on the metabolism of S-adenosylhomocysteine in mouse L929 cells.
Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; Animals; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Homocysteine; Hydrolases; Mice; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1988 |
Broad-spectrum antiviral activities of neplanocin A, 3-deazaneplanocin A, and their 5'-nor derivatives.
Topics: Adenosine; Animals; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; HeLa Cells; Mice; Reoviridae; Respirovirus; Rotavirus; Simplexvirus; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication | 1989 |
4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cattle; Hydrolases; Liver; Phosphorylation | 1992 |
9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Cattle; Hydrolases; Kinetics; Liver; NAD | 1988 |
New neplanocin analogues. 7. Synthesis and antiviral activity of 2-halo derivatives of neplanocin A.
Topics: Adenosine; Animals; Antiviral Agents; Arenaviridae; Chlorocebus aethiops; Cytomegalovirus; Molecular Structure; Parainfluenza Virus 3, Human; Reoviridae; Vaccinia virus; Vero Cells; Vesicular stomatitis Indiana virus | 1996 |
Synthesis of fluorinated cyclopentenyladenine as potent inhibitor of S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosylhomocysteinase; Cyclopentanes; Enzyme Inhibitors; Fluorine; Magnetic Resonance Spectroscopy | 2004 |
X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
Topics: Adenosine; Adenosylhomocysteinase; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Dynamics Simulation; Optical Rotation; Spectrometry, Mass, Fast Atom Bombardment | 2011 |
Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Animals; Brain Chemistry; Drug Design; Enzyme Activation; Enzyme Inhibitors; Homocysteine; Hydrogen Bonding; Hydrolases; Inhibitory Concentration 50; Models, Molecular; Rats; S-Adenosylhomocysteine; Substrate Specificity | 2014 |