neoechinulin-a and oxybenzone

neoechinulin-a has been researched along with oxybenzone* in 1 studies

Other Studies

1 other study(ies) available for neoechinulin-a and oxybenzone

Article	Year
Golmaenone, a new diketopiperazine alkaloid from the marine-derived fungus Aspergillus sp. Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:3 A new diketopiperazine alkaloid, golmaenone (1). and related alkaloids, neoechinulin A (2). and L-alanyl-L-tryptophan anhydride (3). have been isolated from the culture broth of the marine-derived fungus Aspergillus sp. The structure and absolute stereochemistry of the new compound (1). was assigned by spectroscopic methods and the advanced Marfey's method. Compounds 1 and 2 exhibited a significant radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) with IC(50) values of 20 and 24 microM, respectively, which are similar to the positive control, ascorbic acid (IC(50), 20 microM). Compounds 1 and 2 also showed an ultraviolet-A (UV-A) (320--390 nm) protecting activity with ED(50) values of 90 and 170 microM, respectively, which are more active than oxybenzone (ED(50), 350 microM) currently being used as sunscreen. Topics: Ascorbic Acid; Aspergillus; Benzophenones; Biphenyl Compounds; Dipeptides; Free Radical Scavengers; Indole Alkaloids; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Picrates; Piperazines; Sunscreening Agents; Ultraviolet Rays	2004

Article

Year

Golmaenone, a new diketopiperazine alkaloid from the marine-derived fungus Aspergillus sp.

Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:3

A new diketopiperazine alkaloid, golmaenone (1). and related alkaloids, neoechinulin A (2). and L-alanyl-L-tryptophan anhydride (3). have been isolated from the culture broth of the marine-derived fungus Aspergillus sp. The structure and absolute stereochemistry of the new compound (1). was assigned by spectroscopic methods and the advanced Marfey's method. Compounds 1 and 2 exhibited a significant radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) with IC(50) values of 20 and 24 microM, respectively, which are similar to the positive control, ascorbic acid (IC(50), 20 microM). Compounds 1 and 2 also showed an ultraviolet-A (UV-A) (320--390 nm) protecting activity with ED(50) values of 90 and 170 microM, respectively, which are more active than oxybenzone (ED(50), 350 microM) currently being used as sunscreen.

Topics: Ascorbic Acid; Aspergillus; Benzophenones; Biphenyl Compounds; Dipeptides; Free Radical Scavengers; Indole Alkaloids; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Picrates; Piperazines; Sunscreening Agents; Ultraviolet Rays

2004