Compounds > nelfinavir
Page last updated: 2024-08-24

nelfinavir and elacridar

nelfinavir has been researched along with elacridar in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Anderson, BD; Edwards, JE; McNamara, PJ; Morgan, ME; Savolainen, J1
Alcorn, J; Anderson, BD; Edwards, JE; McNamara, PJ; Savolainen, J1
Bui, T; Ho, RJ; Kelly, EJ; Salama, NN1
Agarwal, S; Chen, Y; Elmquist, WF; Giri, N; Pan, G; Shaik, N1
Elmquist, WF; Giri, N; Shaik, N1

Other Studies

8 other study(ies) available for nelfinavir and elacridar

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effects of a P-glycoprotein inhibitor on brain and plasma concentrations of anti-human immunodeficiency virus drugs administered in combination in rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:5

    Topics: Acridines; Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Drug Interactions; HIV Protease Inhibitors; Isoquinolines; Male; Nelfinavir; Prodrugs; Purine Nucleosides; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines

2002
Role of P-glycoprotein in distribution of nelfinavir across the blood-mammary tissue barrier and blood-brain barrier.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:4

    Topics: Acridines; Animals; Animals, Newborn; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Female; HIV Protease Inhibitors; Lactation; Mammary Glands, Animal; Milk; Nelfinavir; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines

2005
The impact of pharmacologic and genetic knockout of P-glycoprotein on nelfinavir levels in the brain and other tissues in mice.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:6

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; HIV Protease Inhibitors; Male; Mice; Mice, Knockout; Nelfinavir; Tetrahydroisoquinolines; Tissue Distribution

2005
Substrate-dependent breast cancer resistance protein (Bcrp1/Abcg2)-mediated interactions: consideration of multiple binding sites in in vitro assay design.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:3

    Topics: Acridines; Adenosine; Animals; Binding Sites; Cell Line; Diketopiperazines; Dogs; Heterocyclic Compounds, 4 or More Rings; Nelfinavir; Neoplasm Proteins; Poloxamer; Protein Binding; Tetrahydroisoquinolines

2009
Investigation of the micellar effect of pluronic P85 on P-glycoprotein inhibition: cell accumulation and equilibrium dialysis studies.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:11

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line; Cell-Free System; Cells; Dialysis; Dideoxynucleosides; Diphenylhexatriene; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Fluorescent Dyes; HIV-1; Inhibitory Concentration 50; Mannitol; Micelles; Nelfinavir; Permeability; Poloxamer; Protease Inhibitors; Saquinavir; Surface-Active Agents; Temperature; Tetrahydroisoquinolines; Time Factors

2009