nefopam has been researched along with morphine in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (35.00) | 18.7374 |
| 1990's | 3 (7.50) | 18.2507 |
| 2000's | 14 (35.00) | 29.6817 |
| 2010's | 7 (17.50) | 24.3611 |
| 2020's | 2 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Frey, LG; Winter, JC | 1 |
| Beaver, WT; Feise, GA | 1 |
| Phillips, G; Vickers, MD | 1 |
| Bellville, JW; Gasser, JC | 1 |
| Laska, E; Sunshine, A | 1 |
| Ambrogi, F; Cassano, GB; Marazziti, D; Rotondo, A | 1 |
| Kenny, GN; Moffat, AC; Prentice, JW | 1 |
| Jasinski, DR; Preston, KL | 1 |
| Aitken, H; Howie, JC; Kenny, GN; Lawrie, S; McArdle, CS; McLintock, TT | 1 |
| Casali, R; Masci, P; Novelli, GP; Piscitelli, P | 1 |
| Morton, AK; Pleuvry, BJ; Stainthorp, SF | 1 |
| Wörz, R | 1 |
| Piercey, MF; Schroeder, LA | 1 |
| Nimmo, WS; Todd, JG | 1 |
| Hirayama, T; Irikura, T; Taga, F | 1 |
| Campos, VM; Solis, EL | 1 |
| Kanui, TI; Karim, F; Towett, PK | 1 |
| Fletcher, D; Gillon, MC; Incagnoli, P; Josse, C; Kuhlman, L; Mimoz, O; Mirand, A; Soilleux, H | 1 |
| Taylor, MS | 1 |
| Coppe, MC; Gillardin, JM; Girard, P; Pansart, Y | 1 |
| Alquier, C; Aubrun, F; Chauvin, M; Du Manoir, B; Fletcher, D; Langlois, M; Le Guern, ME | 1 |
| Bhageerutty, K; Cazals, C; Tramoni, G; Viale, JP | 1 |
| Beloeil, H; Benhamou, D; Delage, N; Mazoit, JX; Nègre, I | 1 |
| Gillardin, JM; Girard, P; Pansart, Y | 1 |
| Alfonsi, P; Chauvin, M; Guignard, B; Kapfer, B; Sessler, DI | 1 |
| Bougault, A; Dupuis, JL; Mehaddi, Y; Merle, JC; Nathan, N; Odin, I; Vandroux, D | 1 |
| Clevenot, D; Debaene, B; Derrode, N; Fletcher, D; Rolland, D; Tirault, M | 1 |
| Bertin, P | 1 |
| Attali, JY; Aveline, C; Bonnet, F; Cognet, F; Gautier, JF; Hetet, HL; Leborgne, P; Leconte, V; Vautier, P | 1 |
| Barbier, M; Bonnal, A; Colson, P; Deras, P; Morau, E | 1 |
| Djerada, Z; Fournet-Fayard, A; Gozalo, C; Lamiable, D; Lelarge, C; Malinovsky, JM; Millart, H | 1 |
| Guyot, B; Jaouen, E; Jathières, F; Jolly, C; Keïta, H; Torre, A | 1 |
| Albaladejo, P; Bosson, JL; Greze, J; Incagnoli, P; Palombi, O; Payen, JF; Quesada, JL; Tonetti, J; Vighetti, A | 1 |
| Alonso, S; Casano, F; Cuvillon, P; Demattei, C; L'hermite, J; Lefrant, JY; Muller, L; Ripart, J; Zoric, L | 1 |
| Albaladejo, P; Aubrun, F; Belbachir, A; Bellissant, E; Beloeil, H; Durand, M; Fessenmeyer, C; Futier, E; Lasocki, S; Martinez, V; Minville, V; Renault, A; Sion, A; Verzili, D | 1 |
| Boontanapibul, K; Pinsornsak, P; Sukkarnkosol, S | 1 |
| Homprasert, C; Nitising, A; Pantubtim, C; Raksakietisak, M; Rushatamukayanunt, P; Sawasdiwipachai, P; Wilaiwan, K | 1 |
2 review(s) available for nefopam and morphine
| Article | Year |
|---|---|
Managing postoperative pain.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Morphine; Nefopam; Oxycodone; Pain, Postoperative; Preanesthetic Medication; Tramadol | 2001 |
[What are the cardiovascular complications of the analgesics and glucocorticoids?].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Cardiovascular Diseases; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Glucocorticoids; Humans; Morphine; Nalbuphine; Nefopam; Risk Assessment; Risk Factors; Time Factors; Tramadol | 2006 |
22 trial(s) available for nefopam and morphine
| Article | Year |
|---|---|
A comparison of the analgesic effect of intramuscular nefopam and morphine in patients with postoperative pain.
Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Morphine; Nefopam; Oxazocines; Pain, Postoperative | 1977 |
Nefopam in postoperative pain.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Oxazocines; Pain, Postoperative; Random Allocation; Time Factors | 1979 |
Respiratory effects of nefopam.
Topics: Clinical Trials as Topic; Depression, Chemical; Humans; Male; Morphine; Nefopam; Oxazocines; Placebos; Respiration; Time Factors | 1975 |
Nefopam and morphine in man.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Oxazocines; Pain; Pain, Postoperative; Time Factors | 1975 |
Postoperative nefopam and diclofenac. Evaluation of their morphine-sparing effect after upper abdominal surgery.
Topics: Abdomen; Adult; Aged; Diclofenac; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Oxazocines; Pain, Postoperative; Random Allocation | 1990 |
Assessment of the analgesic efficacy of nefopam hydrochloride after upper abdominal surgery: a study using patient controlled analgesia.
Topics: Abdomen; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Oxazocines; Pain Measurement; Pain, Postoperative; Random Allocation; Self Administration; Time Factors | 1988 |
Effect of premedication on drug absorption and gastric emptying.
Topics: Acetaminophen; Adult; Aged; Diazepam; Female; Gastric Emptying; Humans; Intestinal Absorption; Male; Middle Aged; Morphine; Naloxone; Nefopam; Preanesthetic Medication; Time Factors | 1983 |
The analgesic and hypothermic effects of nefopam, morphine, aspirin, diphenhydramine, and placebo.
Topics: Administration, Oral; Analgesics; Aspirin; Body Temperature; Diphenhydramine; Double-Blind Method; Humans; Injections, Intramuscular; Morphine; Nefopam; Oxazocines; Placebos; Time Factors | 1980 |
Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Administration Schedule; Drug Therapy, Combination; Female; Hepatectomy; Humans; Male; Middle Aged; Morphine; Nefopam; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prodrugs | 2001 |
Randomized prospective study of the analgesic effect of nefopam after orthopaedic surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies | 2003 |
Morphine-sparing effect of nefopam by continuous intravenous injection after abdominal surgery by laparotomy.
Topics: Abdomen; Analgesics, Non-Narcotic; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Laparoscopy; Male; Middle Aged; Morphine; Nefopam; Pain Measurement; Pain, Postoperative; Prospective Studies; Time Factors | 2003 |
The median effective dose of nefopam and morphine administered intravenously for postoperative pain after minor surgery: a prospective randomized double-blinded isobolographic study of their analgesic action.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Nefopam; Oxygen; Pain, Postoperative; Prospective Studies | 2004 |
Nefopam and ketamine comparably enhance postoperative analgesia.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Endpoint Determination; Female; Humans; Ketamine; Male; Middle Aged; Morphine; Nefopam; Pain Measurement; Pain, Postoperative | 2005 |
[Analgesic effect of continuous intravenous nefopam after urological surgery].
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Humans; Infusions, Intravenous; Laparotomy; Male; Middle Aged; Morphine; Nefopam; Neuropsychological Tests; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Urologic Surgical Procedures, Male | 2005 |
The effect of nefopam on morphine overconsumption induced by large-dose remifentanil during propofol anesthesia for major abdominal surgery.
Topics: Adult; Aged; Digestive System Surgical Procedures; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Pain, Postoperative; Piperidines; Propofol; Prospective Studies; Remifentanil | 2006 |
Postoperative analgesia and early rehabilitation after total knee replacement: a comparison of continuous low-dose intravenous ketamine versus nefopam.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Dissociative; Arthroplasty, Replacement, Knee; Double-Blind Method; Female; Humans; Infusions, Intravenous; Ketamine; Knee; Male; Morphine; Nefopam; Pain Measurement; Pain, Postoperative; Treatment Outcome | 2009 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Breast Feeding; Bupivacaine; Celecoxib; Cesarean Section; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Humans; Levobupivacaine; Morphine; Nefopam; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Young Adult | 2015 |
Does continuous wound infiltration enhance baseline intravenous multimodal analgesia after posterior spinal fusion surgery? A randomized, double-blinded, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Pain, Postoperative; Spinal Fusion | 2017 |
Opioid-sparing effect of nefopam in combination with paracetamol after major abdominal surgery: a randomized double-blind study.
Topics: Abdomen; Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Pain, Postoperative; Prospective Studies | 2017 |
Multicentre, prospective, double-blind, randomised controlled clinical trial comparing different non-opioid analgesic combinations with morphine for postoperative analgesia: the OCTOPUS study.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ketoprofen; Male; Middle Aged; Morphine; Nefopam; Pain Measurement; Pain, Postoperative; Postoperative Care; Treatment Outcome | 2019 |
Does Nefopam Provide Analgesic Effect and Reduce Morphine Consumption After Primary Total Knee Arthroplasty? A Prospective, Double-Blind, Randomized Controlled Trial.
Topics: Analgesics; Analgesics, Opioid; Antiemetics; Arthroplasty, Replacement, Knee; Double-Blind Method; Humans; Morphine; Nefopam; Pain, Postoperative; Prospective Studies | 2022 |
Postoperative analgesia of intraoperative nefopam in patients undergoing anterior cervical spine surgery: A prospective randomized controlled trial.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Cervical Vertebrae; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Humans; Morphine; Nefopam; Neuralgia; Pain, Postoperative; Prospective Studies | 2022 |
16 other study(ies) available for nefopam and morphine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Comparison of the discriminative stimulus properties of nefopam and morphine.
Topics: Animals; Discrimination Learning; Drug Interactions; Female; Morphine; Naloxone; Nefopam; Oxazocines; Rats | 1979 |
Analgesia by nefopam: does it act through serotonin?
Topics: Analgesia; Blood Platelets; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Morphine; Nefopam; Orphenadrine; Serotonin Antagonists | 1991 |
A comparative assay of nefopam, morphine and d-amphetamine.
Topics: Behavior; Dextroamphetamine; Dose-Response Relationship, Drug; Humans; Male; Morphine; Nefopam; Oxazocines; Substance-Related Disorders | 1987 |
[Nefopam in postoperative analgesia. Comparison with meperidine and morphine].
Topics: Adult; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Meperidine; Middle Aged; Morphine; Nefopam; Oxazocines; Pain, Postoperative | 1988 |
The effects of nefopam on blood acid-base status in the rabbit: interactions with morphine in the mouse and rabbit.
Topics: Acid-Base Equilibrium; Analgesics; Animals; Carbon Dioxide; Drug Interactions; Female; Hydrogen-Ion Concentration; Male; Mice; Morphine; Nefopam; Oxazocines; Rabbits; Respiration; Species Specificity | 1980 |
Control of cancer pain with analgesics acting in the central nervous system.
Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Neoplasms; Pain; Pentazocine; Tilidine; Tramadol | 1984 |
Spinal and Supraspinal sites for morphine and nefopam analgesia in the mouse.
Topics: Analgesia; Animals; Brain; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Nefopam; Neurons, Afferent; Oxazocines; Receptors, Opioid; Spinal Cord | 1981 |
Electrophysiological investigations on the mode of action of nefopam, a novel analgesic agent.
Topics: Afferent Pathways; Animals; Cerebral Cortex; Electroencephalography; Electrophysiology; Evoked Potentials; Male; Morphine; Nefopam; Nervous System; Oxazocines; Rabbits; Splanchnic Nerves; Thalamus | 1981 |
The formalin test in the naked mole-rat (Heterocephalus glaber): analgesic effects of morphine, nefopam and paracetamol.
Topics: Acetaminophen; Analgesics; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Formaldehyde; Morphine; Nefopam; Nociceptors; Pain; Rodentia | 1993 |
Nefopam reduces thermal hypersensitivity in acute and postoperative pain models in the rat.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Hot Temperature; Hyperalgesia; Male; Morphine; Nefopam; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Tramadol | 2001 |
Nefopam potentiates morphine antinociception in allodynia and hyperalgesia in the rat.
Topics: Analgesics; Animals; Drug Synergism; Hyperalgesia; Male; Morphine; Nefopam; Pain Threshold; Rats; Rats, Sprague-Dawley | 2004 |
[Assessment of practices in postoperative analgesia in caesarean before and after implementation of an information program].
Topics: Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics; Anesthesia, General; Anesthesia, Obstetrical; Breast Feeding; Cesarean Section; Cicatrix; Drug Therapy, Combination; Elective Surgical Procedures; Emergencies; Female; Humans; Ketoprofen; Medical Audit; Mobility Limitation; Morphine; Narcotics; Nefopam; Pain Measurement; Pain, Postoperative; Patients; Practice Patterns, Physicians'; Pregnancy; Prospective Studies; Quality Improvement | 2013 |
Population pharmacokinetics of nefopam in elderly, with or without renal impairment, and its link to treatment response.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Area Under Curve; Female; Glomerular Filtration Rate; Humans; Logistic Models; Male; Models, Biological; Monte Carlo Method; Morphine; Nefopam; Renal Insufficiency | 2014 |