nefopam and clonidine

nefopam has been researched along with clonidine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (26.67)18.2507
2000's9 (60.00)29.6817
2010's1 (6.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Nomura, K; Ohkubo, Y; Yamaguchi, I1
Conti, G; de Blasi, RA; Gasparetto, A; La Rosa, I; Orsi, P; Pinto, G; Rosa, G; Sanitá, R1
Gray, AM; Nevinson, MJ; Sewell, RD1
Boldt, J; Kumle, B; Maleck, WH; Piper, SN; Schmidt, CC; Suttner, SW1
Bilotta, F; Rosa, G1
Boldt, J; Kranke, P; Maleck, WH; Piper, SN; Röhm, KD; Suttner, SW1
Eberhart, LH; Kranke, P; Roewer, N; Tramèr, MR1
Bilotta, F; Ferri, F; Giovannini, F; Pinto, G; Rosa, G1
Amrouni, H; Andrieu, G; Carnaille, B; Lebuffe, G; Pattou, F; Robin, E; Vallet, B; Wattier, JM1
Alfonsi, P; Chauvin, M; Gaude-Joindreau, V; Guignard, B; Passard, A; Sessler, DI1
Liu, M; Lv, M; Qu, W; Wang, X; Wang, Y1
Al-Dahna, T; Dinges, HC; Eberhart, L; Rücker, G; Schubert, AK; Wiesmann, T; Wulf, H1

Reviews

3 review(s) available for nefopam and clonidine

ArticleYear
Single-dose parenteral pharmacological interventions for the prevention of postoperative shivering: a quantitative systematic review of randomized controlled trials.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:3

    Topics: Clonidine; Dose-Response Relationship, Drug; Humans; Nefopam; Postoperative Complications; Randomized Controlled Trials as Topic; Shivering

2004
Nefopam for the prevention of perioperative shivering: a meta-analysis of randomized controlled trials.
    BMC anesthesiology, 2015, Jun-09, Volume: 15

    Topics: Analgesics, Non-Narcotic; Anesthesia; Clonidine; Humans; Intraoperative Complications; Nefopam; Randomized Controlled Trials as Topic; Shivering

2015
Pharmacologic interventions for the therapy of postanesthetic shivering in adults: a systematic review and network meta-analysis.
    Minerva anestesiologica, 2023, Volume: 89, Issue:10

    Topics: Adult; Clonidine; Doxapram; Humans; Meperidine; Methylphenidate; Nefopam; Network Meta-Analysis; Shivering; Tramadol

2023

Trials

6 trial(s) available for nefopam and clonidine

ArticleYear
Control of post anaesthetic shivering with nefopam hydrochloride in mildly hypothermic patients after neurosurgery.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:1

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Basal Metabolism; Blood Pressure; Body Temperature; Brain; Carbon Dioxide; Cerebrospinal Fluid Pressure; Cerebrovascular Circulation; Clonidine; Elective Surgical Procedures; Electroencephalography; Energy Metabolism; Female; Humans; Hypothermia; Male; Meperidine; Nefopam; Oxygen Consumption; Postoperative Period; Shivering

1995
Nefopam and clonidine in the prevention of postanaesthetic shivering.
    Anaesthesia, 1999, Volume: 54, Issue:7

    Topics: Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Anesthesia, General; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Nefopam; Placebos; Postanesthesia Nursing; Shivering

1999
A comparison of nefopam and clonidine for the prevention of postanaesthetic shivering: a comparative, double-blind and placebo-controlled dose-ranging study.
    Anaesthesia, 2004, Volume: 59, Issue:6

    Topics: Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Anesthesia, General; Blood Pressure; Body Temperature; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Infant, Newborn; Male; Middle Aged; Nefopam; Postoperative Complications; Severity of Illness Index; Shivering

2004
Nefopam or clonidine in the pharmacologic prevention of shivering in patients undergoing conscious sedation for interventional neuroradiology.
    Anaesthesia, 2005, Volume: 60, Issue:2

    Topics: Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Blood Pressure; Clonidine; Conscious Sedation; Double-Blind Method; Ephedrine; Female; Heart Rate; Humans; Male; Middle Aged; Nefopam; Neuroradiography; Prospective Studies; Radiology, Interventional; Severity of Illness Index; Shivering; Vasoconstrictor Agents

2005
Analgesic efficacy of bilateral superficial cervical plexus block administered before thyroid surgery under general anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Blood Pressure; Cervical Plexus; Clonidine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Nefopam; Nerve Block; Pain Measurement; Pain, Postoperative; Ropivacaine; Sufentanil; Thyroidectomy

2007
Nefopam and alfentanil additively reduce the shivering threshold in humans whereas nefopam and clonidine do not.
    Anesthesiology, 2009, Volume: 111, Issue:1

    Topics: Adult; Alfentanil; Body Temperature; Clonidine; Drug Synergism; Humans; Male; Nefopam; Shivering; Single-Blind Method; Young Adult

2009

Other Studies

6 other study(ies) available for nefopam and clonidine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Involvement of dopamine in the mechanism of action of FR64822, a novel non-opioid antinociceptive compound.
    European journal of pharmacology, 1991, Nov-05, Volume: 204, Issue:2

    Topics: Acetates; Acetic Acid; Analgesics; Animals; Clonidine; Dopamine; Dopamine Antagonists; Male; Mice; Mice, Inbred Strains; Nefopam; Pain; Pain Measurement; Pyridines; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine

1991
The involvement of opioidergic and noradrenergic mechanisms in nefopam antinociception.
    European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3

    Topics: Abdominal Pain; Acetic Acid; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Idazoxan; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nefopam; Pain Measurement; Receptors, Adrenergic; Receptors, Opioid

1999
Pharmacological prevention of postanesthetic shivering.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:4

    Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Antiemetics; Clonidine; Humans; Indoles; Nefopam; Postoperative Complications; Quinolizines; Shivering

2002