neferine has been researched along with liensinine in 20 studies
| Studies (neferine) | Trials (neferine) | Recent Studies (post-2010) (neferine) | Studies (liensinine) | Trials (liensinine) | Recent Studies (post-2010) (liensinine) |
|---|---|---|---|---|---|
| 165 | 0 | 120 | 51 | 0 | 34 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 11 (55.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jing, MX; Nong, Y; Wang, JL | 1 |
| Chen, Y; Fan, G; Mitchell, A; Wu, H; Wu, Y | 1 |
| Bian, BL; Liu, W; Si, N; Wang, HJ | 1 |
| Jin, Y; Wang, JL; Zhao, LB | 1 |
| Hu, BR; Huang, Y; Li, S; Liu, P; Wang, JL; Xiang, JZ; Zhao, LB | 1 |
| Li, XZ; Liang, YZ; Liu, S; Qi, LF; Wang, B | 1 |
| Bai, Y; Huang, Y; Liu, P; Wang, J; Xiang, J; Zhao, L | 1 |
| Dong, ZX; Gu, DF; Hu, MQ; Hu, XX; Li, BX; Shi, YQ; Yang, BF; Zhang, J; Zhao, X | 1 |
| Jin, Y; Liang, Z; Wei, T; Zhang, L | 1 |
| Bi, H; Huang, M; Jiang, H; Shen, Q; Yu, L; Zeng, S; Zhou, H; Zhou, Q | 1 |
| Guo, ZB; Xie, Y; Zeng, SX; Zhang, LT; Zhang, Y; Zheng, BD | 1 |
| Bu, T; Chen, D; Chen, ZC; Dong, YY; Ge, RS; Hu, G; Wang, YY; Xu, RA; Yao, WW | 1 |
| Gong, Y; Li, B; Liu, Q; Liu, T; Liu, Z; Shao, C; Wang, R; Wang, X; Wu, T; Zhang, X | 1 |
| Itoh, A; Nakajima, H; Nishimura, K; Oshiro, H; Sugimoto, Y; Sun, S; Tanahashi, T; Toda, T; Yamada, J | 1 |
| Lan, F; Li, M; Li, S; Liu, C; Sun, S; Wang, S; Yu, Y; Zhang, Q | 1 |
| Chen, HB; Lin, MT; Tang, SL; Zhang, C; Zhang, JY; Zhao, ZZ | 1 |
| Pan, Y; Sun, J; Xiao, M; Yang, GM; Zhang, JL; Zhu, MS | 1 |
| An, L; Jiang, Y; Liu, CM; Pan, B; Wu, Z; Zhou, J; Zhu, C | 1 |
| Huang, C; Wang, S; Wang, X; Wu, Y; Yang, P; Yang, Y; Zhou, Z | 1 |
| Gao, YH; Jiang, JY; Li, S; Lin, HR; Ma, BT; Wang, HB; Wu, MC; Xue, MF; Zhang, C | 1 |
20 other study(ies) available for neferine and liensinine
| Article | Year |
|---|---|
[Effects of liensinine on haemodynamics in rats and the physiologic properties of isolated rabbit atria].
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Benzylisoquinolines; Female; Hemodynamics; In Vitro Techniques; Isoquinolines; Male; Myocardial Contraction; Phenols; Quinidine; Rabbits; Rats; Rats, Sprague-Dawley; Verapamil | 1992 |
Separation, identification and rapid determination of liensine, isoliensinine and neferine from embryo of the seed of Nelumbo nucifera Gaertn. by liquid chromatography coupled to diode array detector and tandem mass spectrometry.
Topics: Alkaloids; Benzylisoquinolines; Calibration; Chromatography, High Pressure Liquid; Isoquinolines; Mass Spectrometry; Nelumbo; Phenols; Plant Extracts; Reproducibility of Results; Seeds; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2007 |
[Study on preparation technology of plumula nelumbinis Alkaloid Dripping Pill and determination of content by HPLC].
Topics: Alkaloids; Benzylisoquinolines; Chromatography, High Pressure Liquid; Isoquinolines; Microspheres; Nelumbo; Particle Size; Phenols; Plants, Medicinal; Polyethylene Glycols; Quality Control; Seeds; Solubility; Technology, Pharmaceutical | 2007 |
[Determination of three alkaloids in total alkaloids exfracts from Lotus plumule by RP-HPLC].
Topics: Alkaloids; Benzylisoquinolines; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Isoquinolines; Lotus; Phenols; Plants, Medicinal; Reproducibility of Results; Seeds | 2007 |
[Metabolic products and pathway of neferine in rat liver].
Topics: Administration, Oral; Alcohol Oxidoreductases; Animals; Aryl Hydrocarbon Hydroxylases; Benzylisoquinolines; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P450 Family 2; Isoquinolines; Ketoconazole; Male; Microsomes, Liver; Nelumbo; Phenols; Plants, Medicinal; Quinidine; Rats; Seeds; Spectrometry, Mass, Electrospray Ionization | 2007 |
Preparative separation and purification of liensinine, isoliensinine and neferine from seed embryo of Nelumbo nucifera GAERTN using high-speed counter-current chromatography.
Topics: Benzylisoquinolines; Chromatography, High Pressure Liquid; Countercurrent Distribution; Isoquinolines; Magnetic Resonance Spectroscopy; Nelumbo; Phenols; Plant Extracts; Seeds | 2009 |
Simultaneous determination of liensinine, isoliensinine and neferine from seed embryo of Nelumbo nucifera Gaertn. in rat plasma by a rapid HPLC method and its application to a pharmacokinetic study.
Topics: Administration, Oral; Animals; Area Under Curve; Benzylisoquinolines; Calibration; Chromatography, High Pressure Liquid; Female; Half-Life; Injections, Intravenous; Isoquinolines; Male; Nelumbo; Phenols; Rats; Rats, Wistar; Reference Standards; Reproducibility of Results; Seeds; Solutions; Spectrophotometry, Ultraviolet | 2011 |
Comparative effects of liensinine and neferine on the human ether-a-go-go-related gene potassium channel and pharmacological activity analysis.
Topics: Animals; Anti-Arrhythmia Agents; Benzylisoquinolines; Binding Sites; Cell Membrane; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Isoquinolines; Membrane Potentials; Patch-Clamp Techniques; Phenols; Potassium Channel Blockers; Rats; Rats, Wistar; Structure-Activity Relationship; Time Factors; Tissue Distribution; Transfection | 2012 |
[Effect of berberine, liensinine and neferine on HERG channel expression].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzylisoquinolines; Berberine; Blotting, Western; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluorescent Antibody Technique; Gene Expression Regulation; HEK293 Cells; Humans; Isoquinolines; Male; Phenols; Rats | 2013 |
In vitro characterization of ABC transporters involved in the absorption and distribution of liensinine and its analogs.
Topics: Absorption; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Biological Transport; Caco-2 Cells; Cell Survival; Dogs; Humans; Isoquinolines; Madin Darby Canine Kidney Cells; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Phenols | 2013 |
Protective effects of alkaloid compounds from Nelumbinis Plumula on tert-butyl hydroperoxide-induced oxidative stress.
Topics: Alkaloids; Benzylisoquinolines; Biphenyl Compounds; Drug Evaluation, Preclinical; Free Radical Scavengers; Free Radicals; Glutathione; Hep G2 Cells; Humans; Isoquinolines; L-Lactate Dehydrogenase; Malondialdehyde; Nelumbo; Oxidants; Oxidative Stress; Phenols; Picrates; Plant Extracts; Reactive Oxygen Species; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances | 2013 |
Simultaneous determination of liensinine, isoliensinine and neferine in rat plasma by UPLC-MS/MS and application of the technique to pharmacokinetic studies.
Topics: Administration, Intravenous; Animals; Benzylisoquinolines; Chromatography, Liquid; Isoquinolines; Male; Phenols; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2015 |
Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation.
Topics: Apoptosis; Benzylisoquinolines; Cell Line, Tumor; Enzyme Activation; Female; Humans; Isoquinolines; MAP Kinase Signaling System; MCF-7 Cells; p38 Mitogen-Activated Protein Kinases; Phenols; Reactive Oxygen Species; Triple Negative Breast Neoplasms | 2015 |
Serotonergic mechanisms are involved in antidepressant-like effects of bisbenzylisoquinolines liensinine and its analogs isolated from the embryo of Nelumbo nucifera Gaertner seeds in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzylisoquinolines; Disease Models, Animal; Dose-Response Relationship, Drug; Isoquinolines; Male; Mice, Inbred ICR; Motor Activity; Nelumbo; Phenols; Phytotherapy; Plant Extracts; Plants, Medicinal; Seeds; Serotonergic Neurons; Serotonin Agents; Stress, Psychological; Swimming | 2015 |
Liensinine- and Neferine-Induced Cardiotoxicity in Primary Neonatal Rat Cardiomyocytes and Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Topics: Animals; Benzylisoquinolines; Cardiotoxicity; Cells, Cultured; Drugs, Chinese Herbal; Female; Humans; Induced Pluripotent Stem Cells; Isoquinolines; Male; Myocytes, Cardiac; Phenols; Rats; Rats, Sprague-Dawley | 2016 |
[Metabolites Identification for Alkaloids from Nelumbinis Plumula in Caco-2 Cells by LC/MS/MS].
Topics: Alkaloids; Benzylisoquinolines; Caco-2 Cells; Chromatography, Liquid; Drugs, Chinese Herbal; Humans; Isoquinolines; Magnoliopsida; Metabolic Networks and Pathways; Methylation; Molecular Weight; Phenols; Tandem Mass Spectrometry; Tetrahydroisoquinolines | 2015 |
Isolation and identification of a tribenzylisoquinoline alkaloid from Nelumbo nucifera Gaertn, a novel potential smooth muscle relaxant.
Topics: Alkaloids; Animals; Benzylisoquinolines; Female; In Vitro Techniques; Isoquinolines; Male; Mice, Inbred C57BL; Molecular Structure; Muscle, Smooth; Nelumbo; Neuromuscular Agents; Phenols; Seeds | 2018 |
The antiandrogenic effect of neferine, liensinine, and isoliensinine by inhibiting 5-α-reductase and androgen receptor expression via PI3K/AKT signaling pathway in prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Amino Acid Chloromethyl Ketones; Androgen Antagonists; Androgen Receptor Antagonists; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Benzylisoquinolines; Biological Products; Cell Line, Tumor; Cell Movement; Chromones; Heterocyclic Compounds, 3-Ring; Humans; Isoquinolines; Male; Morpholines; Nelumbo; Phenols; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction | 2021 |
Inhibitory effect on SARS-CoV-2 infection of neferine by blocking Ca
Topics: Antiviral Agents; Benzylisoquinolines; Calcium; Cell Line; Coronavirus; COVID-19; HEK293 Cells; Humans; Isoquinolines; Phenols; SARS-CoV-2; Virus Internalization | 2021 |
Liensinine and neferine exert neuroprotective effects via the autophagy pathway in transgenic Caenorhabditis elegans.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Animals; Animals, Genetically Modified; Autophagy; Benzylisoquinolines; Caenorhabditis elegans; Humans; Neuroblastoma; Neuroprotective Agents | 2023 |