nefazodone and sertraline

nefazodone has been researched along with sertraline in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (33.33)18.2507
2000's11 (33.33)29.6817
2010's11 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carlier, PR; Lo, MM; Lo, PC; Reynolds, IJ; Richelson, E; Sharma, TA; Tatsumi, M1
Cianchetta, G; Cruciani, G; Fravolini, A; Giesing, D; Singleton, RW; Vaz, RJ; Wildgoose, M; Zhang, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Jung, ME; Kang, SY; Kim, HJ; Kim, J; Kim, MJ; Kim, MS; Lee, J; Lee, KN; Lee, M; Lee, SH; Park, EJ; Park, WK; Seo, HJ; Son, EJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Preskorn, SH1
Feiger, A; Kiev, A; Shrivastava, RK; Wilcox, CS; Wisselink, PG1
Bryant, SG1
Reynolds, RD1
Yonkers, KA1
Anand, VS; Dewan, MJ1
Farvolden, P; Mancini, C; Oakman, JM; Van Ameringen, M1
Michael, A; Praseedom, A; Tubbe, PA1
Dunn, NR; Freemantle, SN; Mackay, FR; Mann, RD; Martin, RM; Pearce, GL1
Jurima-Romet, M; Neigh, S; Wright, M1
Court, MH; Duan, SX; Greenblatt, DJ; Hesse, LM; Shader, RI; Venkatakrishnan, K; von Moltke, LL1
Ferguson, JM1
Borian, F; Ferguson, JM; Hartford, JT; Ieni, J; Jody, D; McQuade, RD; Shrivastava, RK; Stahl, SM1
Olivier, B; Waldinger, MD; Zwinderman, AH1
Bagby, RM; Grigoriadis, S; Kennedy, SH1
Cheng, KT; DeVane, CL; Donovan, JL; Liston, HL; Markowitz, JS; Risch, SC; Willard, L1
Bayles-Dazet, W; Brady, KT; Killeen, TK; McRae, AL; Mellman, TA; Sonne, SC; Timmerman, MA1
Olivier, B; Schweitzer, DH; Waldinger, MD; Zwinderman, AH1
Hoge, CW; Lee, DJ; Rasmusson, AM; Schnitzlein, CW; Vythilingam, M; Wolf, JP1
Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X1

Reviews

6 review(s) available for nefazodone and sertraline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Comparison of the tolerability of bupropion, fluoxetine, imipramine, nefazodone, paroxetine, sertraline, and venlafaxine.
    The Journal of clinical psychiatry, 1995, Volume: 56 Suppl 6

    Topics: 1-Naphthylamine; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder; Drug Design; Drug Tolerance; Drugs, Investigational; Fluoxetine; Humans; Imipramine; Paroxetine; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Triazoles; Venlafaxine Hydrochloride

1995
Anxiety symptoms and anxiety disorders: how are they related to premenstrual disorders?
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 3

    Topics: 1-Naphthylamine; Adult; Age of Onset; Anxiety; Anxiety Disorders; Buspirone; Carbon Dioxide; Comorbidity; Depressive Disorder; Diagnosis, Differential; Female; Humans; Mental Disorders; Panic Disorder; Piperazines; Premenstrual Syndrome; Psychotherapy; Risk Factors; Sertraline; Sodium Lactate; Triazoles

1997
The effects of antidepressants on sexual functioning in depressed patients: a review.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 3

    Topics: Adult; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Male; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Sexual Behavior; Sexual Dysfunctions, Psychological; Sexuality; Single-Blind Method; Triazoles

2001
PSYCHOTHERAPY VERSUS PHARMACOTHERAPY FOR POSTTRAUMATIC STRESS DISORDER: SYSTEMIC REVIEW AND META-ANALYSES TO DETERMINE FIRST-LINE TREATMENTS.
    Depression and anxiety, 2016, Volume: 33, Issue:9

    Topics: Antidepressive Agents; Combined Modality Therapy; Humans; Piperazines; Psychotherapy; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride

2016
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride

2016

Trials

6 trial(s) available for nefazodone and sertraline

ArticleYear
Nefazodone versus sertraline in outpatients with major depression: focus on efficacy, tolerability, and effects on sexual function and satisfaction.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 2

    Topics: 1-Naphthylamine; Adolescent; Adult; Ambulatory Care; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Orgasm; Piperazines; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sertraline; Severity of Illness Index; Sexual Behavior; Treatment Outcome; Triazoles

1996
Reemergence of sexual dysfunction in patients with major depressive disorder: double-blind comparison of nefazodone and sertraline.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Humans; Incidence; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Recurrence; Sertraline; Sexual Dysfunctions, Psychological; Treatment Outcome; Triazoles

2001
Antidepressants and ejaculation: a double-blind, randomized, placebo-controlled, fixed-dose study with paroxetine, sertraline, and nefazodone.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antidepressive Agents; Chi-Square Distribution; Double-Blind Method; Ejaculation; Humans; Male; Middle Aged; Paroxetine; Piperazines; Placebos; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline; Triazoles

2001
A comparison of antidepressant response in younger and older women.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:4

    Topics: Adult; Aged; Aging; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive Disorder; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Sertraline; Sex Characteristics; Triazoles

2003
Comparative CYP3A4 inhibitory effects of venlafaxine, fluoxetine, sertraline, and nefazodone in healthy volunteers.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:1

    Topics: Administration, Oral; Adult; Alprazolam; Area Under Curve; Breath Tests; Carbon Radioisotopes; Cross-Over Studies; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Delayed-Action Preparations; Drug Administration Schedule; Erythromycin; Fluoxetine; Half-Life; Humans; Male; Middle Aged; Molecular Probes; Piperazines; Sertraline; Triazoles; Venlafaxine Hydrochloride

2004
Comparison of nefazodone and sertraline for the treatment of posttraumatic stress disorder.
    Depression and anxiety, 2004, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperazines; Sertraline; Stress Disorders, Post-Traumatic; Treatment Outcome; Triazoles

2004

Other Studies

21 other study(ies) available for nefazodone and sertraline

ArticleYear
Synthesis of a potent wide-spectrum serotonin-, norepinephrine-, dopamine-reuptake inhibitor (SNDRI) and a species-selective dopamine-reuptake inhibitor based on the gamma-amino alcohol functional group.
    Bioorganic & medicinal chemistry letters, 1998, Mar-03, Volume: 8, Issue:5

    Topics: Amino Alcohols; Animals; Antidepressive Agents; Dopamine; Humans; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Serotonin; Species Specificity

1998
A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.
    Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Fluoresceins; Fluorescent Dyes; Humans; Models, Molecular; Multivariate Analysis; Permeability; Quantitative Structure-Activity Relationship

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT(2A) receptor and 5-HT transporter.
    Journal of medicinal chemistry, 2011, Sep-22, Volume: 54, Issue:18

    Topics: Animals; Antidepressive Agents; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Mice; Motor Activity; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Reassessment of nefazodone.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Oct-01, Volume: 53, Issue:19

    Topics: 1-Naphthylamine; Antidepressive Agents, Second-Generation; Humans; Paroxetine; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Triazoles

1996
Sertraline-induced anorgasmia treated with intermittent nefazodone.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:2

    Topics: 1-Naphthylamine; Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Humans; Male; Orgasm; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Sexual Dysfunctions, Psychological; Triazoles

1997
Evaluating the tolerability of the newer antidepressants.
    The Journal of nervous and mental disease, 1999, Volume: 187, Issue:2

    Topics: Antidepressive Agents; Bupropion; Central Nervous System Diseases; Citalopram; Cyclohexanols; Delayed-Action Preparations; Drug Information Services; Fluvoxamine; Gastrointestinal Diseases; Guidelines as Topic; Humans; Incidence; Paroxetine; Piperazines; Placebos; Selective Serotonin Reuptake Inhibitors; Sertraline; Sexual Dysfunctions, Psychological; Triazoles; United States; United States Agency for Healthcare Research and Quality; Venlafaxine Hydrochloride

1999
Serotonergic agents in the treatment of social phobia in children and adolescents: a case series.
    Depression and anxiety, 1999, Volume: 10, Issue:1

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Child; Female; Humans; Male; Paroxetine; Phobic Disorders; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome; Triazoles

1999
Sertraline-induced anorgasmia reversed by nefazodone.
    The British journal of psychiatry : the journal of mental science, 1999, Volume: 175

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Ejaculation; Humans; Libido; Male; Middle Aged; Piperazines; Sertraline; Triazoles

1999
Newer antidepressants: a comparison of tolerability in general practice.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 1999, Volume: 49, Issue:448

    Topics: Adult; Aged; Antidepressive Agents; Cohort Studies; Cyclohexanols; Depressive Disorder; Family Practice; Female; Fluoxetine; Humans; Male; Middle Aged; Moclobemide; Paroxetine; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Triazoles; Venlafaxine Hydrochloride

1999
Terfenadine-antidepressant interactions: an in vitro inhibition study using human liver microsomes.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:3

    Topics: Alkylation; Antidepressive Agents, Second-Generation; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Fluoxetine; Histamine H1 Antagonists; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Piperazines; Sertraline; Terfenadine; Triazoles

1998
CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:10

    Topics: Antibodies; Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Fluvoxamine; Humans; Hydroxylation; Isoenzymes; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Paroxetine; Piperazines; Sertraline; Triazoles

2000
Geometric mean IELT and premature ejaculation: appropriate statistics to avoid overestimation of treatment efficacy.
    The journal of sexual medicine, 2008, Volume: 5, Issue:2

    Topics: Antidepressive Agents; Coitus; Data Interpretation, Statistical; Ejaculation; Fluoxetine; Fluvoxamine; Humans; Male; Mianserin; Mirtazapine; Models, Biological; Piperazines; Reaction Time; Research Design; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Sertraline; Sexual Dysfunction, Physiological; Treatment Outcome; Triazoles

2008