Page last updated: 2024-09-03

ne 58051 and 2-(2-pyridyl)ethylidine-1,1-bisphosphonate

ne 58051 has been researched along with 2-(2-pyridyl)ethylidine-1,1-bisphosphonate in 2 studies

Compound Research Comparison

Studies (ne 58051)	Trials (ne 58051)	Recent Studies (post-2010) (ne 58051)	Studies (2-(2-pyridyl)ethylidine-1,1-bisphosphonate)	Trials (2-(2-pyridyl)ethylidine-1,1-bisphosphonate)	Recent Studies (post-2010) (2-(2-pyridyl)ethylidine-1,1-bisphosphonate)
17	0	2	6	0	0

Protein Interaction Comparison

Protein	Taxonomy	ne 58051 (IC50)	2-(2-pyridyl)ethylidine-1,1-bisphosphonate (IC50)
Farnesyl pyrophosphate synthase	Homo sapiens (human)		0.1446

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Martin, MB; Oldfield, E; Szabo, CM	1
Barnett, BL; Dunford, JE; Ebetino, FH; Kavanagh, KL; Kwaasi, AA; Oppermann, U; Rogers, MJ; Russell, RG	1

Other Studies

2 other study(ies) available for ne 58051 and 2-(2-pyridyl)ethylidine-1,1-bisphosphonate

Article	Year
An investigation of bone resorption and Dictyostelium discoideum growth inhibition by bisphosphonate drugs. Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14 Topics: Alkyl and Aryl Transferases; Animals; Bone Resorption; Crystallography, X-Ray; Dictyostelium; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Inhibitory Concentration 50; Models, Molecular; Quantitative Structure-Activity Relationship; Rats	2002
Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Binding Sites; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Models, Molecular; Molecular Structure; Nitrogen; Stereoisomerism; Structure-Activity Relationship; Time Factors	2008

Article

Year

An investigation of bone resorption and Dictyostelium discoideum growth inhibition by bisphosphonate drugs.

Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14

Topics: Alkyl and Aryl Transferases; Animals; Bone Resorption; Crystallography, X-Ray; Dictyostelium; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Inhibitory Concentration 50; Models, Molecular; Quantitative Structure-Activity Relationship; Rats

2002

Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.

Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

Topics: Binding Sites; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Models, Molecular; Molecular Structure; Nitrogen; Stereoisomerism; Structure-Activity Relationship; Time Factors

2008