Page last updated: 2024-09-05

nbi 27914 and dmp 696

nbi 27914 has been researched along with dmp 696 in 3 studies

Compound Research Comparison

Studies
(nbi 27914)
Trials
(nbi 27914)
Recent Studies (post-2010)
(nbi 27914)
Studies
(dmp 696)
Trials
(dmp 696)
Recent Studies (post-2010) (dmp 696)
760293104

Protein Interaction Comparison

ProteinTaxonomynbi 27914 (IC50)dmp 696 (IC50)
Histamine H1 receptorCavia porcellus (domestic guinea pig)0.0398
Corticotropin-releasing factor receptor 1Homo sapiens (human)0.0504
Corticotropin-releasing factor receptor 1Rattus norvegicus (Norway rat)0.0042

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gilligan, PJ; Robertson, DW; Zaczek, R1
Brodbeck, R; De Lombaert, S; Doller, D; Fung, L; Ge, P; Gulianello, M; Hodgetts, KJ; Hoffman, D; Horvath, RF; Kehne, JH; Kieltyka, A; Krause, JE; Lee, Y; Maynard, GD; Yoon, T1
Crowe, PD; Grigoriadis, DE; Hoare, SR; Ling, N; Schwarz, DA; Sullivan, SK; Vale, WW1

Reviews

1 review(s) available for nbi 27914 and dmp 696

ArticleYear
Corticotropin releasing factor (CRF) receptor modulators: progress and opportunities for new therapeutic agents.
    Journal of medicinal chemistry, 2000, May-04, Volume: 43, Issue:9

    Topics: Amino Acid Sequence; Animals; Humans; Molecular Sequence Data; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological

2000

Other Studies

2 other study(ies) available for nbi 27914 and dmp 696

ArticleYear
Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.
    Journal of medicinal chemistry, 2011, Jun-23, Volume: 54, Issue:12

    Topics: Adipose Tissue; Administration, Oral; Adrenocorticotropic Hormone; Animals; Biological Availability; Blood-Brain Barrier; Cell Line; Cerebral Cortex; Humans; In Vitro Techniques; Injections, Intraventricular; Male; Microsomes, Liver; Motor Activity; Pyrazines; Radioligand Assay; Rats; Receptors, Corticotropin-Releasing Hormone; Restraint, Physical; Structure-Activity Relationship

2011
Ligand affinity for amino-terminal and juxtamembrane domains of the corticotropin releasing factor type I receptor: regulation by G-protein and nonpeptide antagonists.
    Biochemistry, 2004, Apr-06, Volume: 43, Issue:13

    Topics: Amphibian Proteins; Aniline Compounds; Animals; Binding, Competitive; Cell Line; Corticotropin-Releasing Hormone; Extracellular Space; GTP-Binding Proteins; Humans; Ligands; Models, Chemical; Peptide Fragments; Peptide Hormones; Peptides; Protein Binding; Protein Structure, Tertiary; Pyrazoles; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Triazines; Urocortins

2004