nbi 27914 has been researched along with cp 154526 in 6 studies
| Studies (nbi 27914) | Trials (nbi 27914) | Recent Studies (post-2010) (nbi 27914) | Studies (cp 154526) | Trials (cp 154526) | Recent Studies (post-2010) (cp 154526) |
|---|---|---|---|---|---|
| 76 | 0 | 29 | 20 | 0 | 5 |
| 76 | 0 | 29 | 129 | 1 | 40 |
| Protein | Taxonomy | nbi 27914 (IC50) | cp 154526 (IC50) |
|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Homo sapiens (human) | 0.0134 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C; Dagnino, R; Grigoriadis, DE; Huang, CQ; McCarthy, JR | 1 |
| Balanda, LA; Browman, KE; Burris, KD; Dubowchik, GM; Fiedler, T; Fung, L; Gao, Q; James, CA; Michne, JA; Pin, SS; Ruediger, EH; Schwartz, W; Scola, PM; Taber, MT; Wu, D; Zhang, J; Zuev, D | 1 |
| Balanda, LA; Browman, KE; Burris, KD; Dubowchik, GM; Fiedler, T; Fung, LK; Han, X; Michne, JA; Pin, SS; Taber, MT; Zhang, J | 1 |
| Brodbeck, R; De Lombaert, S; Doller, D; Fung, L; Ge, P; Gulianello, M; Hodgetts, KJ; Hoffman, D; Horvath, RF; Kehne, JH; Kieltyka, A; Krause, JE; Lee, Y; Maynard, GD; Yoon, T | 1 |
| Gilligan, PJ; Robertson, DW; Zaczek, R | 1 |
| Cummons, T; Harrison, JE; Hummel, M; Kennedy, JD; Lu, P; Mark, L; Whiteside, GT | 1 |
1 review(s) available for nbi 27914 and cp 154526
| Article | Year |
|---|---|
Corticotropin releasing factor (CRF) receptor modulators: progress and opportunities for new therapeutic agents.
Topics: Amino Acid Sequence; Animals; Humans; Molecular Sequence Data; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological | 2000 |
5 other study(ies) available for nbi 27914 and cp 154526
| Article | Year |
|---|---|
1-Alkyl-3-amino-5-aryl-1H-[1,2,4]triazoles: novel synthesis via cyclization of N-acyl-S-methylisothioureas with alkylhydrazines and their potent corticotropin-releasing factor-1 (CRF(1)) receptor antagonist activities.
Topics: Humans; Hydrazines; Magnetic Resonance Spectroscopy; Receptors, Corticotropin-Releasing Hormone; Thiourea; Triazoles | 2001 |
2-arylaminothiazoles as high-affinity corticotropin-releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy.
Topics: Animals; Binding Sites; Humans; Kinetics; Rats; Receptors, Corticotropin-Releasing Hormone; Structure-Activity Relationship; Thiazoles | 2003 |
Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Blood-Brain Barrier; Corticotropin-Releasing Hormone; Humans; Imidazoles; Mice; Rats; Receptors, Corticotropin-Releasing Hormone; Structure-Activity Relationship | 2005 |
Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.
Topics: Adipose Tissue; Administration, Oral; Adrenocorticotropic Hormone; Animals; Biological Availability; Blood-Brain Barrier; Cell Line; Cerebral Cortex; Humans; In Vitro Techniques; Injections, Intraventricular; Male; Microsomes, Liver; Motor Activity; Pyrazines; Radioligand Assay; Rats; Receptors, Corticotropin-Releasing Hormone; Restraint, Physical; Structure-Activity Relationship | 2011 |
Pain is a salient "stressor" that is mediated by corticotropin-releasing factor-1 receptors.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Corticotropin-Releasing Hormone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hyperalgesia; Indomethacin; Inflammation; Male; Mice; Pain; Pain Threshold; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Spinal Cord Injuries; Stomach Ulcer; Stress, Psychological | 2010 |