Compounds > naxagolide
Page last updated: 2024-08-24

naxagolide and raclopride

naxagolide has been researched along with raclopride in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.09)18.2507
2000's9 (40.91)29.6817
2010's11 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nobrega, JN; Seeman, P1
Day, J; Fibiger, HC1
Ginovart, N; Houle, S; Hussey, D; Kapur, S; Seeman, P; Willeit, M; Wilson, AA1
Bloomfield, PM; Galineau, L; Ginovart, N; Houle, S; Kapur, S; Mizrahi, R; Seeman, P; Willeit, M; Wilson, AA1
Galineau, L; Garcia, A; Ginovart, N; Houle, S; Kapur, S; Wilson, AA1
Gmeiner, P; Kapur, S; Seeman, P; Wilson, A1
Guillin, O; Hwang, DR; Hwang, Y; Laruelle, M; Narendran, R; Rabiner, E; Reeder, S; Scher, E; Slifstein, M1
Ginovart, N; Graff-Guerrero, A; Kapur, S; Mamo, D; Mizrahi, R; Rusjan, P; Seeman, P; Vitcu, I; Willeit, M; Wilson, AA1
Kapur, S; McCormick, PN; Seeman, P; Wilson, AA1
Adams, JR; Boileau, I; Furukawa, Y; Guttman, M; Hornykiewicz, O; Houle, S; Kapur, S; Kish, SJ; Rusjan, P; Tong, J; Wilson, AA1
Barsoum, P; Graff-Guerrero, A; Houle, S; Kapur, S; Mamo, D; Marcon, H; Mizrahi, R; Rusjan, P; Shammi, CM; Wilson, AA1
Ahmad, R; Brickute, D; Egerton, A; Grasby, PM; Hirani, E; Howes, OD; Luthra, SK; Rosso, L; Turton, DR1
Ding, M; Dorff, P; Elmore, CS; Maier, D; Malmquist, J; Mrzljak, L; Peng, T; Ström, P; Tuke, D; Werkheiser, J; Widzowski, D; Zysk, J1
Ginovart, N; McCormick, PN; Wilson, AA1
Bobok, A; Horti, F; Kiss, B1
Abanades, S; Beaver, JD; Colasanti, A; Gunn, RN; Huiban, M; Laruelle, M; Miller, SR; Plisson, C; Rabiner, EA; Searle, GE; Shotbolt, P; Tziortzi, AC; van der Aart, J1
Carson, RE; Cosgrove, KP; Gallezot, JD; Huang, Y; Kloczynski, T; Labaree, D; Lim, K; Morris, ED; Pittman, B; Rabiner, EA; Ridler, K; Weinzimmer, D; Zheng, MQ1
Anderson, GM; Baldan, LC; Billingslea, E; Bloch, MH; Crowley, M; de Araujo, I; Ding, YS; Ercan-Sencicek, AG; Gallezot, JD; Gorczyca, R; Hughes, ZA; Krusong, K; Krystal, JH; Leventhal, BL; Loring, E; Mayes, L; Ohtsu, H; Panza, KE; Pittenger, C; Pogorelov, V; Rapanelli, M; State, MW; Wasylink, S; Williams, KA1
Alexoff, D; Carter, P; Fowler, JS; Kang, Y; Kim, D; Kim, SW; King, P; Logan, J; Muench, L; Shea, C; Skolnick, P; Volkow, ND1
Abi-Jaoude, E; Cho, SS; Houle, S; Lang, AE; Obeso, I; Rusjan, P; Sandor, P; Segura, B; Strafella, AP1
Boileau, I; Caravaggio, F; Chung, JK; Gerretsen, P; Graff-Guerrero, A; Houle, S; Mamo, DC; Nakajima, S; Plitman, E; Wilson, AA1
Boileau, I; Caravaggio, F; Chakravarty, MM; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Kim, J; Ku Chung, J; Patel, R; Plitman, E; Remington, G1

Trials

1 trial(s) available for naxagolide and raclopride

ArticleYear
The effect of antipsychotics on the high-affinity state of D2 and D3 receptors: a positron emission tomography study With [11C]-(+)-PHNO.
    Archives of general psychiatry, 2009, Volume: 66, Issue:6

    Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzodiazepines; Benzothiazoles; Binding, Competitive; Carbon Radioisotopes; Caudate Nucleus; Clozapine; Dopamine Agonists; Dopamine Antagonists; Double-Blind Method; Female; Globus Pallidus; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Olanzapine; Oxazines; Positron-Emission Tomography; Pramipexole; Putamen; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D3; Risperidone; Schizophrenia

2009

Other Studies

21 other study(ies) available for naxagolide and raclopride

ArticleYear
Dopamine D2 receptors mapped in rat brain with [3H](+)PHNO.
    Synapse (New York, N.Y.), 1994, Volume: 17, Issue:3

    Topics: Animals; Autoradiography; Brain; Brain Chemistry; Brain Mapping; Densitometry; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Guanine Nucleotides; Guanylyl Imidodiphosphate; In Vitro Techniques; Ligands; Male; Oxazines; Raclopride; Rats; Rats, Wistar; Salicylamides; Spiperone

1994
Dopaminergic regulation of cortical acetylcholine release: effects of dopamine receptor agonists.
    Neuroscience, 1993, Volume: 54, Issue:3

    Topics: Acetylcholine; Animals; Apomorphine; Benzazepines; Cerebral Cortex; Dialysis; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Ergolines; Indoles; Male; Nerve Endings; Oxazines; Phenanthridines; Quinpirole; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides

1993
High-affinity states of human brain dopamine D2/3 receptors imaged by the agonist [11C]-(+)-PHNO.
    Biological psychiatry, 2006, Mar-01, Volume: 59, Issue:5

    Topics: Adult; Brain; Brain Mapping; Carbon Radioisotopes; Dopamine Antagonists; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Oxazines; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Reference Values

2006
Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography.
    Journal of neurochemistry, 2006, Volume: 97, Issue:4

    Topics: Amphetamine; Animals; Binding Sites; Binding, Competitive; Brain; Brain Chemistry; Carbon Radioisotopes; Cats; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Oxazines; Positron-Emission Tomography; Presynaptic Terminals; Raclopride; Receptors, Dopamine D2; Synaptic Transmission

2006
In vivo characterization of the pharmacokinetics and pharmacological properties of [11C]-(+)-PHNO in rats using an intracerebral beta-sensitive system.
    Synapse (New York, N.Y.), 2006, Volume: 60, Issue:2

    Topics: Amphetamine; Animals; Binding, Competitive; Brain; Brain Chemistry; Carbon Radioisotopes; Cerebellum; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Male; Molecular Structure; Oxazines; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2

2006
Dopamine D2 and D3 receptors in human putamen, caudate nucleus, and globus pallidus.
    Synapse (New York, N.Y.), 2006, Sep-01, Volume: 60, Issue:3

    Topics: Animals; Binding, Competitive; Caudate Nucleus; CHO Cells; Cloning, Molecular; Cricetinae; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Globus Pallidus; Humans; In Vitro Techniques; Oxazines; Piperazines; Putamen; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Dopamine D3; Remoxipride; Thiophenes

2006
Dopamine (D2/3) receptor agonist positron emission tomography radiotracer [11C]-(+)-PHNO is a D3 receptor preferring agonist in vivo.
    Synapse (New York, N.Y.), 2006, Dec-01, Volume: 60, Issue:7

    Topics: Animals; Binding, Competitive; Brain; Brain Mapping; Carbon Radioisotopes; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Down-Regulation; Female; Globus Pallidus; Male; Oxazines; Papio anubis; Piperazines; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D3; Species Specificity; Time Factors

2006
Brain region binding of the D2/3 agonist [11C]-(+)-PHNO and the D2/3 antagonist [11C]raclopride in healthy humans.
    Human brain mapping, 2008, Volume: 29, Issue:4

    Topics: Adult; Binding, Competitive; Brain Mapping; Carbon Radioisotopes; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Globus Pallidus; Humans; Male; Neostriatum; Oxazines; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Substantia Nigra; Time Factors; Tissue Distribution

2008
Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo.
    Nuclear medicine and biology, 2008, Volume: 35, Issue:1

    Topics: Animals; Carbon Radioisotopes; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Male; Oxazines; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Tritium

2008
Decreased binding of the D3 dopamine receptor-preferring ligand [11C]-(+)-PHNO in drug-naive Parkinson's disease.
    Brain : a journal of neurology, 2009, Volume: 132, Issue:Pt 5

    Topics: Aged; Binding, Competitive; Carbon Radioisotopes; Case-Control Studies; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; Globus Pallidus; Humans; Male; Middle Aged; Oxazines; Parkinson Disease; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D3; Statistics, Nonparametric

2009
Further evaluation of the carbon11-labeled D(2/3) agonist PET radiotracer PHNO: reproducibility in tracer characteristics and characterization of extrastriatal binding.
    Synapse (New York, N.Y.), 2010, Volume: 64, Issue:4

    Topics: Animals; Binding, Competitive; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine Agonists; Male; Oxazines; Positron-Emission Tomography; Protein Binding; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reproducibility of Results; Tissue Distribution

2010
D2 receptor occupancy in conscious rat brain is not significantly distinguished with [3H]-MNPA, [3H]-(+)-PHNO, and [3H]-raclopride.
    Synapse (New York, N.Y.), 2010, Volume: 64, Issue:8

    Topics: Animals; Apomorphine; Binding Sites; Binding, Competitive; Brain; CHO Cells; Cricetinae; Cricetulus; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Male; Oxazines; Raclopride; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Receptors, G-Protein-Coupled

2010
Isoflurane anaesthesia differentially affects the amphetamine sensitivity of agonist and antagonist D2/D3 positron emission tomography radiotracers: implications for in vivo imaging of dopamine release.
    Molecular imaging and biology, 2011, Volume: 13, Issue:4

    Topics: Amphetamine; Anesthesia; Animals; Cats; Cerebellum; Dopamine; Dopamine D2 Receptor Antagonists; Isoflurane; Male; Neostriatum; Oxazines; Positron-Emission Tomography; Raclopride; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Time Factors

2011
In vitro and in vivo comparison of [³H](+)-PHNO and [³H]raclopride binding to rat striatum and lobes 9 and 10 of the cerebellum: a method to distinguish dopamine D₃ from D₂ receptor sites.
    Synapse (New York, N.Y.), 2011, Volume: 65, Issue:6

    Topics: Animals; Binding, Competitive; Cerebellum; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Ligands; Male; Oxazines; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Staining and Labeling; Tissue Culture Techniques; Tritium

2011
Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012, Volume: 32, Issue:1

    Topics: Adult; Amphetamine; Binding, Competitive; Brain; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Ligands; Male; Middle Aged; Oxazines; Positron-Emission Tomography; Protein Binding; Raclopride; Radioligand Assay; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Dopamine D3; Sensitivity and Specificity

2012
Imaging nicotine- and amphetamine-induced dopamine release in rhesus monkeys with [(11)C]PHNO vs [(11)C]raclopride PET.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:4

    Topics: Amphetamine; Animals; Brain; Central Nervous System Stimulants; Dopamine; Dopamine Agonists; Dopamine Antagonists; Female; Macaca mulatta; Magnetic Resonance Imaging; Nicotine; Nicotinic Agonists; Oxazines; Positron-Emission Tomography; Protein Binding; Raclopride

2014
Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice.
    Neuron, 2014, Jan-08, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Amphetamine; Animals; Brain; Child; Dopamine Agonists; Dopamine Antagonists; Exploratory Behavior; Female; Histidine Decarboxylase; Humans; Male; Maze Learning; Mice; Mice, Knockout; Middle Aged; Mutation; Oxazines; Raclopride; Radionuclide Imaging; Stereotyped Behavior; Time Factors; Tourette Syndrome; Tryptophan; Young Adult

2014
Therapeutic doses of buspirone block D3 receptors in the living primate brain.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:8

    Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Benzazepines; Benzofurans; Buspirone; Corpus Striatum; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Female; Functional Neuroimaging; Globus Pallidus; Injections, Intramuscular; Mesencephalon; Oxazines; Papio anubis; Positron-Emission Tomography; Raclopride; Radioligand Assay; Receptors, Dopamine D3

2014
Similar striatal D2/D3 dopamine receptor availability in adults with Tourette syndrome compared with healthy controls: A [(11) C]-(+)-PHNO and [(11) C]raclopride positron emission tomography imaging study.
    Human brain mapping, 2015, Volume: 36, Issue:7

    Topics: Adolescent; Adult; Corpus Striatum; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Female; Humans; Male; Middle Aged; Oxazines; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D3; Severity of Illness Index; Tourette Syndrome; Young Adult

2015
Lack of age-dependent decrease in dopamine D3 receptor availability: a [(11)C]-(+)-PHNO and [(11)C]-raclopride positron emission tomography study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Volume: 35, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Binding, Competitive; Brain; Brain Chemistry; Carbon Radioisotopes; Caudate Nucleus; Corpus Striatum; Dopamine Agonists; Female; Globus Pallidus; Healthy Volunteers; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Oxazines; Positron-Emission Tomography; Putamen; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D3; Young Adult

2015
The relationship between subcortical brain volume and striatal dopamine D
    Human brain mapping, 2017, Volume: 38, Issue:11

    Topics: Adult; Corpus Striatum; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Organ Size; Oxazines; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Dopamine D3; Thalamus

2017