naproxen has been researched along with triiodothyronine in 10 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (triiodothyronine) | Trials (triiodothyronine) | Recent Studies (post-2010) (triiodothyronine) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 26,247 | 861 | 3,473 |
| Protein | Taxonomy | naproxen (IC50) | triiodothyronine (IC50) |
|---|---|---|---|
| Thyroid hormone receptor alpha | Homo sapiens (human) | 0.0006 | |
| Thyroid hormone receptor beta | Homo sapiens (human) | 0.0006 | |
| Proliferating cell nuclear antigen | Homo sapiens (human) | 3.6 | |
| Thyroid hormone receptor beta | Rattus norvegicus (Norway rat) | 0.0031 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.4109 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Akbar, M; Burke, G; Park, S; Richman, R; Yu, S | 1 |
| Mackenzie, LS; Patel, P; Perez-Diaz, N; Tang, L; Zloh, M | 1 |
| Chen, L; Dai, Q; Guo, H; Liu, J; Liu, W; Niu, L; Sun, X; Tu, W; Xu, C; Ye, J | 1 |
2 review(s) available for naproxen and triiodothyronine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
8 other study(ies) available for naproxen and triiodothyronine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Regulation of thyroid ornithine ornithine decarboxylase (ODC) by thyrotropin. I. The rat.
Topics: Animals; Arachidonic Acids; Aspirin; Bucladesine; Carboxy-Lyases; Colchicine; Cyclic AMP; Indomethacin; Kinetics; Male; Naproxen; Organ Size; Ornithine Decarboxylase; Phenylbutazone; Prostaglandins E; Putrescine; Rats; Thyroid Gland; Thyrotropin; Time Factors; Triiodothyronine; Vinblastine | 1975 |
Evidence that diclofenac and celecoxib are thyroid hormone receptor beta antagonists.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Computer Simulation; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Male; Mesenteric Arteries; Models, Molecular; Naproxen; Rats; Rats, Wistar; Thyroid Hormone Receptors beta; Triiodothyronine; Vasodilation | 2016 |
Long-term exposure to the non-steroidal anti-inflammatory drug (NSAID) naproxen causes thyroid disruption in zebrafish at environmentally relevant concentrations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endocrine Disruptors; Naproxen; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine; Water Pollutants, Chemical; Zebrafish | 2019 |