naproxen has been researched along with tolfenamic acid in 13 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (tolfenamic acid) | Trials (tolfenamic acid) | Recent Studies (post-2010) (tolfenamic acid) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 294 | 47 | 132 |
| Protein | Taxonomy | naproxen (IC50) | tolfenamic acid (IC50) |
|---|---|---|---|
| phospholipase A2 precursor | Homo sapiens (human) | 7.74 | |
| cysteine protease ATG4B isoform a | Homo sapiens (human) | 8.17 | |
| Cytochrome c oxidase subunit 2 | Homo sapiens (human) | 1.29 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bundgaard, H; Nielsen, NM | 1 |
| Charitos, C; Doulgkeris, C; Galanakis, D; Gavalas, A; Kourounakis, AP; Kourounakis, PN; Kravaritou, C; Rekka, EA; Tsiakitzis, KC | 1 |
| Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P | 1 |
| Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P | 1 |
| Huang, S; Li, Y; Liu, W; Zhang, K; Zheng, X | 1 |
| Pradalier, A; Vincent, D | 1 |
| Isomäki, H; Laitinen, O; Nissilä, M; Nuotio, P; Nykänen, E; Seppälä, E; Vapaatalo, H | 1 |
| Isomäki, H; Kaarela, K; Kajander, A; Koota, K; Lehtinen, K; Luukkainen, R; Martio, J; Martio, T; Nissilä, M; Nuotio, P | 1 |
| Ardia, A; Baggio, A; Cornelli, U; Franchini, S | 1 |
| Barbosa, JS; Krymchantowski, AV | 1 |
| Khan, AI; Lei, L; Norquist, AJ; O'Hare, D | 1 |
| Morillo, LE | 2 |
3 review(s) available for naproxen and tolfenamic acid
| Article | Year |
|---|---|
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic | 1992 |
Migraine headache.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Diclofenac; Drug Therapy, Combination; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2003 |
Migraine headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Sumatriptan; Triazoles; Tryptamines | 2004 |
3 trial(s) available for naproxen and tolfenamic acid
| Article | Year |
|---|---|
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic | 1992 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Ketoprofen; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Quinazolines | 1984 |
Comparative studies with tolfenamic acid in rheumatic disorders.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Osteoarthritis; Pain | 1994 |
8 other study(ies) available for naproxen and tolfenamic acid
| Article | Year |
|---|---|
Esters of N,N-disubstituted 2-hydroxyacetamides as a novel highly biolabile prodrug type for carboxylic acid agents.
Topics: Acetamides; Biotransformation; Carboxylic Acids; Half-Life; Humans; Indicators and Reagents; Kinetics; Structure-Activity Relationship | 1987 |
Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholesterol; Cysteine; Drug Evaluation; Gastrointestinal Diseases; Lipoproteins, LDL; Mice; Rats; Triglycerides | 2004 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid | 2015 |
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides | 2016 |
Synergistic effect of tolfenamic acid and glycyrrhizic acid on TPA-induced skin inflammation in mice.
Topics: | 2019 |
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2 | 1985 |
Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Prospective Studies; Secondary Prevention; Serotonin Receptor Agonists; Sumatriptan | 2001 |
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Gemfibrozil; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Naproxen; ortho-Aminobenzoates; Phenylacetates; Valproic Acid | 2001 |