Page last updated: 2024-09-04

naproxen and tiaprofenic acid

naproxen has been researched along with tiaprofenic acid in 20 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(tiaprofenic acid)
Trials
(tiaprofenic acid)
Recent Studies (post-2010) (tiaprofenic acid)
4,5511,0571,4292905818

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)tiaprofenic acid (IC50)
Caspase-1Homo sapiens (human)1.092
Caspase-3Homo sapiens (human)1.092
Caspase-4Homo sapiens (human)1.092
Caspase-5Homo sapiens (human)1.092
Caspase-9Homo sapiens (human)1.092

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19906 (30.00)18.7374
1990's7 (35.00)18.2507
2000's3 (15.00)29.6817
2010's4 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Allegretti, M; Berdini, V; Bertini, R; Bizzarri, C; Cesta, MC; Colotta, F; Di Bello, N; Di Bitondo, R; Di Cioccio, V; Fantucci, P; Florio, S; Galliera, E; Locati, M; Nano, G; Nicolini, L; Russo, V; Topai, A; Zampella, G1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Jones, TA; Nakagawa, A; Smith, CE; Soti, S; Xue, D; Yin, H1
Carney, SL; Hall, LG; Muir, H1
Kauppila, A; Mäkäräinen, L; Mäkilä, UM; Puolakka, J; Seppälä, A1
Brogden, RN; Sorkin, EM1
Clarke, TK; Mungavin, JM1
Daymond, TJ; Diffey, BL; Fairgreaves, H1
Obel, AO1
DiBattista, JA; Martel-Pelletier, J; Pelletier, JP; Ranger, P1
Ersmark, H; Fagertun, H; Høyeraal, HM; Ingemann-Hansen, T; Rönn, O1
Castell, JV; Gomez-Lechon, MJ; Grassa, C; Martinez, LA; Miranda, MA; Tarrega, P1
Becker, L; Eberlein-König, B; Przybilla, B1
Chouini-Lalanne, N; Defais, M; Paillous, N1
el-Bary, AA; el-Nabarawi, MA; Mohamed, MI1
Arslan, S; Hasçelik, Z; Inanici, F; Orhan, H; Sahin, G1
Sadowski, T; Steinmeyer, J1
Chouini-Lalanne, N; Fabre, PL; Hajj, V; Latapie, L; Michaud, S; Noirot, A; Sartor, V1

Reviews

3 review(s) available for naproxen and tiaprofenic acid

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Tiaprofenic acid. A review of its pharmacological properties and therapeutic efficacy in rheumatic diseases and pain states.
    Drugs, 1985, Volume: 29, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Platelets; Drug Evaluation; Drug Interactions; Humans; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Kinetics; Naproxen; Osteoarthritis; Pain; Propionates; Prostaglandins; Rheumatic Diseases; Tissue Distribution

1985
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
    East African medical journal, 1982, Volume: 59, Issue:6

    Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines

1982

Trials

3 trial(s) available for naproxen and tiaprofenic acid

ArticleYear
Tiaprofenic acid in the treatment of primary dysmenorrhoea.
    European journal of obstetrics, gynecology, and reproductive biology, 1986, Volume: 22, Issue:5-6

    Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Naproxen; Propionates; Random Allocation

1986
A multi-centre study of tiaprofenic acid ('Surgam') and five comparative drugs in rheumatoid arthritis and osteoarthritis in general practice.
    Current medical research and opinion, 1983, Volume: 8, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Patient Compliance; Propionates; Sex Factors; Thiazines

1983
Characterization of responders and nonresponders to tiaprofenic acid and naproxen in the treatment of patients with osteoarthritis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Discriminant Analysis; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Propionates; Treatment Outcome

1993

Other Studies

14 other study(ies) available for naproxen and tiaprofenic acid

ArticleYear
2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.
    Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13

    Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Movement; Chemokines, CXC; Chemotaxis, Leukocyte; Female; Humans; Ketoprofen; Ligands; Lymphoma; Macrophages, Peritoneal; Mice; Models, Molecular; Mutagenesis, Site-Directed; Propionates; Receptors, Interleukin-8A; Recombinant Proteins; Structure-Activity Relationship

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.
    Cell chemical biology, 2017, Mar-16, Volume: 24, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Caspase Inhibitors; Caspases; Caspases, Initiator; Cell Line; Cell Survival; High-Throughput Screening Assays; Humans; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Naproxen; Small Molecule Libraries; Substrate Specificity

2017
Effects of tiaprofenic acid and other NSAIDs on proteoglycan metabolism in articular cartilage explants.
    Drugs, 1988, Volume: 35 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cartilage, Articular; Culture Techniques; Dogs; Electrophoresis, Polyacrylamide Gel; Indomethacin; Naproxen; Propionates; Proteoglycans; Sulfur Radioisotopes

1988
Phototoxic reactions to piroxicam, naproxen and tiaprofenic acid.
    British journal of rheumatology, 1983, Volume: 22, Issue:4

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Humans; Male; Naproxen; Osteoarthritis; Photosensitivity Disorders; Piroxicam; Propionates; Thiazines

1983
The reduced expression of glucocorticoid receptors in synovial cells induced by nonsteroidal antiinflammatory drugs can be reversed by prostaglandin E1 analog.
    The Journal of rheumatology, 1994, Volume: 21, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indomethacin; Misoprostol; Naproxen; Propionates; Receptors, Glucocorticoid; Synovial Membrane

1994
Involvement of drug-derived peroxides in the phototoxicity of naproxen and tiaprofenic acid.
    Photochemistry and photobiology, 1993, Volume: 57, Issue:3

    Topics: Aerobiosis; Anaerobiosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Liver; Male; Naproxen; Peroxides; Photolysis; Propionates; Rats; Rats, Sprague-Dawley

1993
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
    Acta dermato-venereologica, 1996, Volume: 76, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocytes; Hemolysis; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Light; Naproxen; Phenylbutazone; Photosensitizing Agents; Piroxicam; Propionates

1996
Nonsteroidal antiinflammatory drug-photosensitized formation of pyrimidine dimer in DNA.
    Biochemical pharmacology, 1998, Feb-15, Volume: 55, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; DNA; DNA Damage; DNA, Single-Stranded; Energy Transfer; In Vitro Techniques; Indomethacin; Ketoprofen; Naproxen; Photochemistry; Photosensitizing Agents; Propionates; Pyrimidine Dimers

1998
Effect of chemical structure on the release of certain propionic acid derivatives from their dosage forms.
    Drug development and industrial pharmacy, 1998, Volume: 24, Issue:5

    Topics: Capsules; Chemical Phenomena; Chemistry, Physical; Dosage Forms; Drug Compounding; Drug Stability; Drug Storage; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Propionates; Suppositories

1998
In vivo effects of non-steroidal antiinflammatory drugs on oxidative stress-related parameters of human erythrocytes.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1999, Volume: 51, Issue:4-5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Erythrocytes; Female; Glutathione Peroxidase; Glutathione Transferase; Humans; Indomethacin; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Naproxen; Oxidative Stress; Propionates

1999
Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Chondrocytes; Diclofenac; Dose-Response Relationship, Drug; Gene Expression Regulation; Indomethacin; Interleukin-1; Meloxicam; Naproxen; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Propionates; RNA, Messenger; Thiazines; Thiazoles

2002
Correlations between electrochemical behaviors and DNA photooxidative properties of non-steroïdal anti-inflammatory drugs and their photoproducts.
    Journal of photochemistry and photobiology. B, Biology, 2012, May-02, Volume: 110

    Topics: Anti-Inflammatory Agents, Non-Steroidal; DNA; Ketoprofen; Naproxen; Photolysis; Photosensitizing Agents; Propionates

2012