Page last updated: 2024-09-04

naproxen and thromboxanes

naproxen has been researched along with thromboxanes in 13 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(thromboxanes)
Trials
(thromboxanes)
Recent Studies (post-2010) (thromboxanes)
4,5511,0571,4293,202149199

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's1 (7.69)18.2507
2000's5 (38.46)29.6817
2010's1 (7.69)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Buchanan, WW; Butt, R; Howard-Lock, H; Kean, WF; Lock, CJ; Rischke, J1
Dahl, H1
Anderson, S; Baird, B; Brater, DC; Campbell, WB1
Burch, RM; Halushka, PV; Wise, WC1
Lefer, AM; Smith, EF1
Cook, GA; Elliott, SL; Hawkey, CJ; McAlindon, ME; Yeomans, ND1
Asfaha, S; McKnight, W; MuscarĂ¡, MN; Wallace, JL1
Branson, J; Ford, M; Kellett, N; Mair, S; Milosavljev, S; Rordorf, C; Scott, G1
Gertz, BJ; Reicin, A; Sperling, RS; Weir, MR1
Day, CA; Jacob, RF; Mason, RP; Walter, MF1
Geisslinger, G; Graff, J; Harder, S; Klinkhardt, U; NĂ¼sing, RM; Seyberth, H; Skarke, C; Watzer, B1
Bliden, KP; Centofanti, R; Gurbel, PA; Jarvis, S; Tantry, US; Troullos, E; Venkataraman, P; Zhu, J1
Hjemdahl, P; Stiller, CO1

Reviews

3 review(s) available for naproxen and thromboxanes

ArticleYear
Selective COX-2 inhibition and cardiovascular effects: a review of the rofecoxib development program.
    American heart journal, 2003, Volume: 146, Issue:4

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Endothelium, Vascular; Epoprostenol; Humans; Isoenzymes; Lactones; Membrane Proteins; Models, Animal; Naproxen; Osteoarthritis; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Sulfones; Thrombosis; Thromboxanes

2003
A biological rationale for the cardiotoxic effects of rofecoxib: comparative analysis with other COX-2 selective agents and NSAids.
    Sub-cellular biochemistry, 2007, Volume: 42

    Topics: Atherosclerosis; Cell Membrane; Cyclooxygenase 2 Inhibitors; Humans; Lactones; Lipid Peroxidation; Lipoproteins, LDL; Naproxen; Prostaglandins I; Risk Factors; Sulfones; Thromboxanes

2007
Lessons from 20 years with COX-2 inhibitors: Importance of dose-response considerations and fair play in comparative trials.
    Journal of internal medicine, 2022, Volume: 292, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Fibrinolytic Agents; Humans; Ibuprofen; Lactones; Naproxen; Prostaglandins; Prostaglandins I; Sulfones; Thromboxanes

2022

Trials

5 trial(s) available for naproxen and thromboxanes

ArticleYear
Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men.
    Kidney international, 1985, Volume: 27, Issue:1

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Kidney; Male; Naproxen; Prostaglandins; Random Allocation; Renin; Sulindac; Thromboxanes

1985
Gastric microbleeding following single and repeated dosing with naproxen.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:6

    Topics: Adaptation, Physiological; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastric Lavage; Gastrointestinal Hemorrhage; Humans; Male; Naproxen; Stomach Diseases; Thromboxanes

1995
Gastroduodenal tolerability of lumiracoxib vs placebo and naproxen: a pilot endoscopic study in healthy male subjects.
    Alimentary pharmacology & therapeutics, 2003, Sep-01, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Endoscopy, Gastrointestinal; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Isoenzymes; Male; Membrane Proteins; Middle Aged; Naproxen; Organic Chemicals; Pilot Projects; Prostaglandin-Endoperoxide Synthases; Thromboxanes

2003
Effects of selective COX-2 inhibition on prostanoids and platelet physiology in young healthy volunteers.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:12

    Topics: Adult; Antigens, Neoplasm; Blood Platelets; Celecoxib; Cell Adhesion; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Fibrinogen; Humans; Lactones; Leukocytes; Male; Naproxen; P-Selectin; Phospholipases A; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoprotein IIb; Prostaglandins; Pyrazoles; Reference Values; Sulfonamides; Sulfones; Thrombin; Thrombomodulin; Thromboxanes; Time Factors

2007
Thromboxane inhibition during concurrent therapy with low-dose aspirin and over-the-counter naproxen sodium.
    Journal of thrombosis and thrombolysis, 2018, Volume: 45, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Naproxen; Platelet Aggregation Inhibitors; Thromboxane B2; Thromboxanes

2018

Other Studies

5 other study(ies) available for naproxen and thromboxanes

ArticleYear
Effect of R and S enantiomers of naproxen on aggregation and thromboxane production in human platelets.
    Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:4

    Topics: Collagen; Female; Humans; In Vitro Techniques; Male; Naproxen; Platelet Aggregation; Platelet Aggregation Inhibitors; Stereoisomerism; Thromboxane A2; Thromboxanes

1989
Naproxen (Naprosyn). Pharmacokinetics: therapeutical relevance and tolerance profile.
    Cephalalgia : an international journal of headache, 1986, Volume: 6 Suppl 4

    Topics: Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Kinetics; Metabolic Clearance Rate; Migraine Disorders; Naproxen; Prostaglandins; Thromboxanes

1986
Prostaglandin-independent inhibition of calcium transport by nonsteroidal anti-inflammatory drugs: differential effects of carboxylic acids and piroxicam.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Biological Transport, Active; Calcium; Carboxylic Acids; Cell Membrane; Cricetinae; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Indomethacin; Ion Channels; Meclofenamic Acid; Microsomes, Liver; Mitochondria, Liver; Naproxen; Piroxicam; Prostaglandins; Rats; Thiazines; Thromboxanes

1983
Stabilization of cardiac lysosomal and cellular membranes in protection of ischemic myocardium due to coronary occlusion:efficacy of the nonsteroidal anti-inflammatory agent, naproxen.
    American heart journal, 1981, Volume: 101, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arterial Occlusive Diseases; Cats; Cell Membrane; Coronary Disease; Creatine Kinase; Lysosomes; Male; Naproxen; Platelet Aggregation; Thromboxane B2; Thromboxanes

1981
Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Celecoxib; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Exudates and Transudates; Gastric Mucosa; Inflammation; Isoenzymes; Male; Membrane Proteins; Naproxen; Nitrates; Nitric Oxide Donors; Nitrites; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Thromboxanes; Wound Healing

2000