naproxen has been researched along with sulindac sulfide in 6 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (sulindac sulfide) | Trials (sulindac sulfide) | Recent Studies (post-2010) (sulindac sulfide) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 212 | 2 | 67 |
| Protein | Taxonomy | naproxen (IC50) | sulindac sulfide (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 2 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.05 | |
| Adenosine receptor A3 | Homo sapiens (human) | 7.231 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.231 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.4015 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 1.092 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.9182 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.231 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bain, G; Beher, D; Chen, W; Jiang, X; Munoz, B; Peachey, J; Prasit, P; Shearman, MS; St-Jacques, R; Stock, N; Williamson, TL; Wrigley, JD | 1 |
| Cook, L; Ternai, B | 1 |
| Beermann, B; Eriksson, LO; Kallner, M | 1 |
| Anderson, SA; Brater, DC; Brown-Cartwright, D | 1 |
| Chremos, AN; Dunn, MJ; Zambraski, EJ | 1 |
| Fukuyama, T; Hayashi, I; Iwatsubo, T; Kan, T; Morohashi, Y; Natsugari, H; Rikimaru, K; Takahashi, Y; Tominari, Y; Tomita, T | 1 |
1 trial(s) available for naproxen and sulindac sulfide
| Article | Year |
|---|---|
Renal function and tubular transport effects of sulindac and naproxen in chronic heart failure.
Topics: Aged; Biological Transport; Body Water; Chronic Disease; Electrolytes; Female; Furosemide; Glomerular Filtration Rate; Heart Failure; Humans; Indenes; Kidney; Kidney Tubules; Naproxen; Prostaglandins; Renal Circulation; Renin; Sulindac | 1987 |
5 other study(ies) available for naproxen and sulindac sulfide
| Article | Year |
|---|---|
The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Mice; Peptide Fragments | 2006 |
Effect of Cu2+ and Zn2+ on the inhibition of human leucocyte elastase by 6-alkyl-3-(omega-carboxyalkyl)-2-pyrone, oleic acid and sulindac sulfide.
Topics: Copper; Diflunisal; Humans; Indenes; Indomethacin; Leukocytes; Naproxen; Oleic Acid; Oleic Acids; Pancreatic Elastase; Pyrans; Pyrones; Structure-Activity Relationship; Sulindac; Zinc | 1989 |
Reversible acute decrease in renal function by NSAIDs in cirrhosis.
Topics: Acute Disease; Creatinine; Female; Humans; Ibuprofen; Indenes; Kidney; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Naproxen; Prostaglandins; Sulindac; Urodynamics | 1987 |
Comparison of the effects of sulindac with other cyclooxygenase inhibitors on prostaglandin excretion and renal function in normal and chronic bile duct-ligated dogs and swine.
Topics: Animals; Bile Ducts; Cyclooxygenase Inhibitors; Dogs; Female; Glomerular Filtration Rate; Ibuprofen; Indenes; Kidney; Ligation; Liver Diseases; Naproxen; Prostaglandins; Sulindac; Swine; Swine, Miniature | 1984 |
Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid Endopeptidases; Cells, Cultured; DNA, Complementary; Dose-Response Relationship, Drug; Endopeptidases; Enzyme-Linked Immunosorbent Assay; HeLa Cells; Humans; Membrane Proteins; Naproxen; Peptide Fragments; Peptides; Protein Binding; Protein Structure, Tertiary; Receptors, Notch; Sulindac | 2003 |