Page last updated: 2024-09-04

naproxen and sulfinpyrazone

naproxen has been researched along with sulfinpyrazone in 14 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(sulfinpyrazone)
Trials
(sulfinpyrazone)
Recent Studies (post-2010) (sulfinpyrazone)
4,5511,0571,4291,12217232

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)sulfinpyrazone (IC50)
fMet-Leu-Phe receptorHomo sapiens (human)14.4
fMet-Leu-Phe receptorHomo sapiens (human)10

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's0 (0.00)18.2507
2000's4 (28.57)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Emmerson, BT1
Ali, M; McDonald, JW1
Burghardt, B; Cardell, M; Janero, DR; Lopez, R1
Kelley, WN; Palella, TD1
Bolli, R; Davenport, N; Epstein, SE; Goldstein, RE1
James, FJ; Nunn, B1

Reviews

3 review(s) available for naproxen and sulfinpyrazone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
Drug control of gout and hyperuricaemia.
    Drugs, 1978, Volume: 16, Issue:2

    Topics: Allopurinol; Arthritis; Chronic Disease; Colchicine; Gout; Humans; Indomethacin; Naproxen; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents

1978

Other Studies

11 other study(ies) available for naproxen and sulfinpyrazone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Reversible and irreversible inhibition of platelet cyclooxygenase and serotonin release by nonsteroidal antinflammatory drugs.
    Thrombosis research, 1978, Volume: 13, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cattle; Collagen; Fenoprofen; Humans; Naproxen; Oxygenases; Phenylbutazone; Serotonin; Serotonin Antagonists; Sulfinpyrazone

1978
Influence of cardioprotective cyclooxygenase and lipoxygenase inhibitors on peroxidative injury to myocardial-membrane phospholipid.
    Biochemical pharmacology, 1989, Dec-15, Volume: 38, Issue:24

    Topics: Aspirin; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipid Peroxidation; Lipid Peroxides; Lipoxygenase Inhibitors; Membrane Lipids; Myocardial Reperfusion Injury; Naproxen; Sulfinpyrazone; Superoxides; Time Factors; Xanthine Oxidase

1989
An approach to hyperuricemia and gout.
    Geriatrics, 1984, Volume: 39, Issue:11

    Topics: Allopurinol; Anti-Inflammatory Agents; Colchicine; Female; Gout; Humans; Male; Naproxen; Phenylbutazone; Prognosis; Sulfinpyrazone; Uric Acid

1984
Influence of sulfinpyrazone and naproxen on infarct size in the dog.
    The American journal of cardiology, 1981, Volume: 47, Issue:4

    Topics: Animals; Constriction, Pathologic; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Male; Myocardial Infarction; Myocardium; Naproxen; Platelet Aggregation; Risk; Sulfinpyrazone

1981
Effect of sulphinpyrazone on human platelet aggregation, 5-hydroxytryptamine release and adhesion ex vivo: comparison with naproxen.
    British journal of clinical pharmacology, 1980, Volume: 9, Issue:3

    Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Humans; In Vitro Techniques; Naproxen; Platelet Adhesiveness; Platelet Aggregation; Serotonin; Sulfinpyrazone

1980