naproxen has been researched along with sk&f 86002 in 3 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (sk&f 86002) | Trials (sk&f 86002) | Recent Studies (post-2010) (sk&f 86002) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 83 | 4 | 13 |
| Protein | Taxonomy | naproxen (IC50) | sk&f 86002 (IC50) |
|---|---|---|---|
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | 3.8 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 5.4 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 10 | |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | 3.8 | |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | 3.8 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 2.1217 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adams, JL; Badger, AM; Boehm, JC; Bradbeer, J; Breton, JJ; Chabot-Fletcher, MC; Gallagher, TF; Garigipati, RS; Griswold, DE; Hillegass, LM; Laydon, JT; Lee, JC; Sheldrake, PL; Smietana, JM; Sorenson, ME | 1 |
| Griswold, DE; Hanna, N; Schwartz, L; Webb, E | 1 |
| Breton, J; Griswold, DE; Marshall, PJ; Torphy, TJ; Webb, EF; White, JR | 1 |
3 other study(ies) available for naproxen and sk&f 86002
| Article | Year |
|---|---|
1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis; Bone Density; Cyclooxygenase Inhibitors; Cytokines; Imidazoles; Lipoxygenase Inhibitors; Mice; Mice, Inbred BALB C; Molecular Structure; Morpholines; Prostaglandin-Endoperoxide Synthases; Protein Kinases; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 1996 |
Arachidonic acid-induced inflammation: inhibition by dual inhibitor of arachidonic acid metabolism, SK&F 86002.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Ibuprofen; Imidazoles; Inflammation; Male; Masoprocol; Mice; Mice, Inbred BALB C; Naproxen; Peritonitis; Piroxicam; Pyrazoles; Thiazoles | 1987 |
Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Ear, External; Eicosanoids; Histamine Release; Humans; Imidazoles; Inflammation; Leukotriene B4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Monocytes; Nadolol; Naproxen; Neutrophils; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrazoles; Pyrrolidinones; Receptors, Adrenergic, beta; Rolipram; SRS-A; Thiazoles | 1993 |