Page last updated: 2024-09-04

naproxen and s 1743

naproxen has been researched along with s 1743 in 28 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(s 1743)
Trials
(s 1743)
Recent Studies (post-2010) (s 1743)
4,5511,0571,4291,228569704

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's22 (78.57)24.3611
2020's6 (21.43)2.80

Authors

AuthorsStudies
Fort, JG; Miner, P; Orlemans, E; Plachetka, J; Sostek, M1
Fort, JG; Goldstein, JL; Hochberg, MC; Hwang, C; Sostek, M; Zhang, Y1
Estborn, L; Fort, JG; Sostek, MB; Vikman, K1
Dhillon, S1
Fort, JG; Hochberg, MC; Hwang, C; Sostek, M; Svensson, O1
Fort, J; Sostek, M; Wang-Smith, L; Zhang, Y1
Cryer, BL; Fort, JG; Hochberg, MC; Hwang, C; Sostek, MB; Svensson, O1
Angiolillo, DJ; Datto, C; Desai, B; Hwang, C; Sostek, M1
Danabal, P; Gopinath, S; Kumar, RS; Shankar, MB1
Angiolillo, DJ; Datto, C; Raines, S; Yeomans, ND1
Choi, HG; Im, YJ; Jeon, JY; Jin, C; Kim, EY; Kim, H; Kim, MG; Kim, Y; Kwak, SS; Lee, SY; Wang, HM1
De Beer, M; De Beer, T; Monteyne, T; Remon, JP; Vervaet, C; Voorspoels, J; Vynckier, AK1
Amer, SM; Lotfy, HM; Mostafa, NS; Zaazaa, HE1
Choi, Y; Han, H; Lim, KS; Shin, D; Yu, KS1
Bello, AE; Fort, JG; Grahn, AY; Holt, RJ; Kent, JD1
Kan, S; Liu, J; Lu, J; Zhang, W; Zhao, Y1
Brozoski, DT; Calvo, AM; Dionísio, TJ; Faria, FA; Lauris, JR; Santos, CF; Simoneti, LF; Torres, EA; Weckwerth, GM; Zupelari-Gonçalves, P1
El-Kimary, EI; Ragab, MAA1
Bao, W; Borer, JS; Graham, DY; Husni, ME; Libby, P; Lincoff, AM; Lüscher, TF; Nissen, SE; Solomon, DH; Stevens, T; Vargo, J; Walker, C; Wang, Q; Wisniewski, LM; Wolski, KE; Yeomans, ND1
Alpan, O; Ball, J; Dare, JA; Francis-Sedlak, M; Goldsmith, D; Gottlieb, B; Gupta, R; Holt, RJ; Jerath, R; Jung, L; LaMoreaux, BD; Lovell, DJ; Naddaf, H; Reinhardt, A; Von Scheven, E; Zeft, A1
Amazonas, RB; Bocchi de Oliveira, MF; Ecclissato, C; Macêdo, EA; Pott Júnior, H; Scheinberg, M1
Kang, CN; Kim, HJ; Kim, JH; Lee, S; Lee, WS; Moon, SH; Park, MS; Shin, SJ1
Kwon, Y; Park, D1
Calvo, AM; Dionísio, TJ; Faria, FC; Morettin, M; Oliveira, GM; Santos, CF1
Li, X; Sun, L; Yang, Y; Zhang, T; Zhou, Q1
An, H; Shin, D1
Calvo, AM; Dionísio, TJ; Faria, FAC; Oliveira, GM; Polanco, NLDH; Santos, CF; Siqueira-Sandrin, VS1

Reviews

1 review(s) available for naproxen and s 1743

ArticleYear
Naproxen/esomeprazole fixed-dose combination: for the treatment of arthritic symptoms and to reduce the risk of gastric ulcers.
    Drugs & aging, 2011, Mar-01, Volume: 28, Issue:3

    Topics: Animals; Arthritis; Drug Combinations; Drug Dosage Calculations; Esomeprazole; Humans; Naproxen; Stomach Ulcer

2011

Trials

17 trial(s) available for naproxen and s 1743

ArticleYear
Clinical trial: evaluation of gastric acid suppression with three doses of immediate-release esomeprazole in the fixed-dose combination of PN 400 (naproxen/esomeprazole magnesium) compared with naproxen 500 mg and enteric-coated esomeprazole 20 mg: a rand
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Anti-Ulcer Agents; Clinical Trials, Phase I as Topic; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Esomeprazole; Female; Gastric Acid; Humans; Magnesium; Male; Middle Aged; Naproxen; Young Adult

2010
Clinical trial: the incidence of NSAID-associated endoscopic gastric ulcers in patients treated with PN 400 (naproxen plus esomeprazole magnesium) vs. enteric-coated naproxen alone.
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Esomeprazole; Humans; Incidence; Magnesium; Middle Aged; Naproxen; Osteoarthritis; Stomach Ulcer; Tablets, Enteric-Coated; Treatment Outcome; Young Adult

2010
Long-term safety of naproxen and esomeprazole magnesium fixed-dose combination: phase III study in patients at risk for NSAID-associated gastric ulcers.
    Current medical research and opinion, 2011, Volume: 27, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Dosage Forms; Drug Combinations; Esomeprazole; Female; Humans; Magnesium Compounds; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Stomach Ulcer; Time Factors

2011
Fixed-dose combination of enteric-coated naproxen and immediate-release esomeprazole has comparable efficacy to celecoxib for knee osteoarthritis: two randomized trials.
    Current medical research and opinion, 2011, Volume: 27, Issue:6

    Topics: Celecoxib; Double-Blind Method; Drug Combinations; Esomeprazole; Humans; Naproxen; Osteoarthritis, Knee; Placebos; Pyrazoles; Sulfonamides; Treatment Outcome

2011
Pharmacokinetics and relative bioavailability of a fixed-dose combination of enteric-coated naproxen and non-enteric-coated esomeprazole magnesium.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biological Availability; Capsules; Cross-Over Studies; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Humans; Least-Squares Analysis; Male; Middle Aged; Models, Biological; Naproxen; Peptic Ulcer; Prospective Studies; Proton Pump Inhibitors; Tablets, Enteric-Coated; Young Adult

2012
A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two randomized, parallel-group, placebo-controlled trials.
    Annals of medicine, 2011, Volume: 43, Issue:8

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Combinations; Dyspepsia; Esomeprazole; Female; Gastrointestinal Tract; Heartburn; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pyrazoles; Sulfonamides; Tablets, Enteric-Coated; Treatment Outcome

2011
Impact of a fixed-dose combination of naproxen and esomeprazole magnesium on serum thromboxane B2 inhibition by low-dose aspirin over 5 days in healthy adults: a phase I, randomized, double-blind, placebo-controlled, noninferiority trial.
    Clinical therapeutics, 2011, Volume: 33, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Combinations; Esomeprazole; Female; Humans; Male; Middle Aged; Naproxen; Pilot Projects; Placebos; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Tablets, Enteric-Coated; Thromboxane B2; Time Factors; United States

2011
Impact of concomitant low-dose aspirin on the safety and tolerability of naproxen and esomeprazole magnesium delayed-release tablets in patients requiring chronic nonsteroidal anti-inflammatory drug therapy: an analysis from 5 Phase III studies.
    Journal of thrombosis and thrombolysis, 2014, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Aspirin; Delayed-Action Preparations; Double-Blind Method; Esomeprazole; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Naproxen; Osteoarthritis

2014
Pharmacokinetic comparison study of a combination containing 500 mg of Naproxen and 20 mg of Esomeprazole: a randomized, single-dose, 2-way crossover, open-label study in healthy Korean men.
    Clinical therapeutics, 2015, Jan-01, Volume: 37, Issue:1

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Asian People; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Drug Combinations; Esomeprazole; Humans; Male; Naproxen; Proton Pump Inhibitors; Republic of Korea; Tandem Mass Spectrometry; Therapeutic Equivalency; Young Adult

2015
Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chemistry, Pharmaceutical; Cross-Over Studies; Drug Combinations; Esomeprazole; Half-Life; Healthy Volunteers; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Naproxen; Proton Pump Inhibitors; Republic of Korea; Young Adult

2015
Onset and durability of pain relief in knee osteoarthritis: Pooled results from two placebo trials of naproxen/esomeprazole combination and celecoxib.
    The Physician and sportsmedicine, 2015, Volume: 43, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Proton Pump Inhibitors

2015
Efficacy of naproxen with or without esomeprazole for pain and inflammation in patients after bilateral third molar extractions: A double blinded crossover study.
    Medicina oral, patologia oral y cirugia bucal, 2017, Jan-01, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Humans; Inflammation; Male; Molar, Third; Naproxen; Pain Management; Pain, Postoperative; Proton Pump Inhibitors; Tooth Extraction; Treatment Outcome; Young Adult

2017
Randomised clinical trial: gastrointestinal events in arthritis patients treated with celecoxib, ibuprofen or naproxen in the PRECISION trial.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:11

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Aspirin; Celecoxib; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Treatment Outcome

2018
A 6-month, multicenter, open-label study of fixed dose naproxen/esomeprazole in adolescent patients with juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2018, Jun-26, Volume: 16, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Drug Therapy, Combination; Esomeprazole; Female; Follow-Up Studies; Humans; Male; Naproxen; Prospective Studies; Proton Pump Inhibitors; Treatment Outcome; United States

2018
Efficacy and safety of a fixed-dose combination of nimesulide/pantoprazole compared to naproxen/esomeprazole for pain relief in patients with osteoarticular diseases and dyspeptic symptoms.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Dyspepsia; Esomeprazole; Female; Humans; Male; Middle Aged; Naproxen; Osteoporosis; Pain; Pain Management; Pantoprazole; Sulfonamides; Tablets

2018
A comparative study of the efficacy of NAXOZOL compared to celecoxib in patients with osteoarthritis.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Double-Blind Method; Esomeprazole; Female; Gastrointestinal Diseases; Humans; Male; Naproxen; Osteoarthritis; Pain; Prospective Studies; Surveys and Questionnaires

2020
Simultaneous separation of naproxen and 6-O-desmethylnaproxen metabolite in saliva samples by liquid chromatography-tandem mass spectrometry: Pharmacokinetic study of naproxen alone and associated with esomeprazole.
    PloS one, 2020, Volume: 15, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Esomeprazole; Female; Gastrointestinal Absorption; Humans; Male; Methanol; Middle Aged; Naproxen; Pain, Procedural; Reproducibility of Results; Saliva; Tablets; Tandem Mass Spectrometry; Young Adult

2020

Other Studies

10 other study(ies) available for naproxen and s 1743

ArticleYear
Naproxen/esomeprazole (Vimovo).
    The Medical letter on drugs and therapeutics, 2010, Sep-20, Volume: 52, Issue:1347

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Combinations; Esomeprazole; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Naproxen; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Treatment Outcome

2010
Development and validation of a sensitive and high-throughput LC-MS/MS method for the simultaneous determination of esomeprazole and naproxen in human plasma.
    Biomedical chromatography : BMC, 2013, Volume: 27, Issue:7

    Topics: Chromatography, Liquid; Drug Stability; Esomeprazole; High-Throughput Screening Assays; Humans; Linear Models; Naproxen; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Temperature

2013
Enteric protection of naproxen in a fixed-dose combination product produced by hot-melt co-extrusion.
    International journal of pharmaceutics, 2015, Aug-01, Volume: 491, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Citrates; Drug Combinations; Drug Compounding; Drug Stability; Esomeprazole; Naproxen; Spectroscopy, Fourier Transform Infrared; Tablets, Enteric-Coated

2015
A comparative study of the novel spectrophotometric methods versus conventional ones for the simultaneous determination of Esomeprazole magnesium trihydrate and Naproxen in their binary mixture.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Volume: 151

    Topics: Cyclooxygenase Inhibitors; Drug Combinations; Esomeprazole; Naproxen; Proton Pump Inhibitors; Spectrophotometry; Tablets

2015
Novel naproxen/esomeprazole magnesium compound pellets based on acid-independent mechanism: in vitro and in vivo evaluation.
    Drug development and industrial pharmacy, 2016, Volume: 42, Issue:9

    Topics: Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Implants; Esomeprazole; Excipients; Humans; Hydrogen-Ion Concentration; Male; Malondialdehyde; Naproxen; Nitric Oxide; Rats; Rats, Sprague-Dawley; Technology, Pharmaceutical

2016
High performance liquid chromatography with photo diode array for separation and analysis of naproxen and esomeprazole in presence of their chiral impurities: Enantiomeric purity determination in tablets.
    Journal of chromatography. A, 2017, May-12, Volume: 1497

    Topics: 2-Propanol; Chromatography, High Pressure Liquid; Esomeprazole; Hexanes; Limit of Detection; Naproxen; Omeprazole; Reproducibility of Results; Stereoisomerism; Tablets; Trifluoroacetic Acid

2017
Factors Affecting Quality of Life and Satisfaction in Patients with Arthritis after Change to a Fixed-Dose Naproxen/Esomeprazole Combination Drug.
    Clinics in orthopedic surgery, 2020, Volume: 12, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Drug Combinations; Esomeprazole; Female; Humans; Male; Middle Aged; Naproxen; Personal Satisfaction; Prospective Studies; Quality of Life; Surveys and Questionnaires; Young Adult

2020
Simultaneous determination of naproxen and esomeprazole in beagle dog plasma by supercritical fluid chromatography-tandem mass spectrometry coupled with evaporation-free liquid-liquid extraction.
    Journal of pharmaceutical and biomedical analysis, 2021, Jan-30, Volume: 193

    Topics: Animals; Chromatography, Supercritical Fluid; Dogs; Esomeprazole; Limit of Detection; Liquid-Liquid Extraction; Naproxen; Reproducibility of Results; Tandem Mass Spectrometry

2021
Multivariate Assessment for Bioequivalence Based on the Correlation of Random Effect.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Area Under Curve; Biological Availability; Biphenyl Compounds; Datasets as Topic; Drug Combinations; Esomeprazole; Humans; Linear Models; Male; Models, Statistical; Multivariate Analysis; Naproxen; Pyrimidines; Randomized Controlled Trials as Topic; Tetrazoles; Therapeutic Equivalency; Tramadol

2021
Simultaneous separation of naproxen and 6-O-desmethylnaproxen metabolite in saliva samples by liquid chromatography-tandem mass spectrometry: Pharmacokinetic study of naproxen alone and associated with esomeprazol-Results.
    PloS one, 2022, Volume: 17, Issue:12

    Topics: Chromatography, Liquid; Esomeprazole; Humans; Naproxen; Saliva; Tandem Mass Spectrometry

2022