naproxen has been researched along with pyrilamine in 8 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (pyrilamine) | Trials (pyrilamine) | Recent Studies (post-2010) (pyrilamine) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 1,860 | 26 | 116 |
| Protein | Taxonomy | naproxen (IC50) | pyrilamine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.13 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.976 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.3 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.997 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.13 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.0126 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.047 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0166 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 2.788 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.879 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.1 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.558 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Caron, G; Ermondi, G | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Ortiz, MI | 1 |
| Grundy, D; Jiang, W; Kirkup, AJ | 1 |
| González-de la Parra, M; Murguía-Cánovas, G; Ortiz, MI; Silva, R; Vargas-López, LC | 1 |
1 review(s) available for naproxen and pyrilamine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
1 trial(s) available for naproxen and pyrilamine
| Article | Year |
|---|---|
Naproxen, paracetamol and pamabrom versus paracetamol, pyrilamine and pamabrom in primary dysmenorrhea: a randomized, double-blind clinical trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Combinations; Dysmenorrhea; Female; Humans; Mexico; Naproxen; Pain Measurement; Propanolamines; Pyrilamine; Tablets; Theophylline; Treatment Outcome; Young Adult | 2016 |
6 other study(ies) available for naproxen and pyrilamine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment.
Topics: Absenteeism; Acetaminophen; Adolescent; Dipyrone; Drug Combinations; Dysmenorrhea; Female; Humans; Menarche; Mexico; Naproxen; Nonprescription Drugs; Pain; Prevalence; Propanolamines; Pyrilamine; Scopolamine; Severity of Illness Index; Students; Theophylline; Universities; Young Adult | 2010 |
Mast cells drive mesenteric afferent signalling during acute intestinal ischaemia.
Topics: Animals; Calcium Channels, L-Type; Gastrointestinal Motility; Hexamethonium; Intestines; Ischemia; Male; Mast Cells; Mesentery; Naproxen; Neurons, Afferent; Nifedipine; omega-Conotoxin GVIA; Pyrilamine; Rats; Reflex; Thioxanthenes; Xanthones | 2011 |