Page last updated: 2024-09-04

naproxen and propofol

naproxen has been researched along with propofol in 7 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(propofol)
Trials
(propofol)
Recent Studies (post-2010) (propofol)
4,5511,0571,42916,8275,1886,805

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)propofol (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)8.1667
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)9.393
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)7.596
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)8.1667
Prostaglandin G/H synthase 1Homo sapiens (human)3.832
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)8.1667
Sodium-dependent noradrenaline transporter Homo sapiens (human)9.393
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)8.3
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)8.1667
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)8.3
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)8.3
5-hydroxytryptamine receptor 2BHomo sapiens (human)5.499
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)8.3
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)8.1667
GABA theta subunitRattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)8.1667

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

3 review(s) available for naproxen and propofol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for naproxen and propofol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010