Compounds > naproxen
Page last updated: 2024-09-04

naproxen and proadifen

naproxen has been researched along with proadifen in 3 studies

Compound Research Comparison

Studies
(naproxen)		Trials
(naproxen)		Recent Studies (post-2010)
(naproxen)		Studies
(proadifen)		Trials
(proadifen)		Recent Studies (post-2010) (proadifen)
4,5511,0571,4291,481035

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)proadifen (IC50)
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.5849
Aldehyde oxidase 1 Rattus norvegicus (Norway rat)1.1

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Awazu, S; Horie, T; Yokoyama, H1
Iley, J; Mendes, E; Moreira, R; Souza, S1

Other Studies

3 other study(ies) available for naproxen and proadifen

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Lipid peroxidation and chemiluminescence during naproxen metabolism in rat liver microsomes.
    Human & experimental toxicology, 1994, Volume: 13, Issue:12

    Topics: Animals; Antimutagenic Agents; Antioxidants; Ascorbic Acid; Cobalt; Electrophoresis, Polyacrylamide Gel; Ferrous Compounds; Histidine; Lipid Peroxidation; Luminescent Measurements; Magnesium Chloride; Male; Microsomes, Liver; Molecular Weight; NADP; Naproxen; Piperonyl Butoxide; Proadifen; Rats; Rats, Wistar; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Vitamin E

1994
Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 9, Issue:2

    Topics: Amides; Animals; Benzoic Acid; Carboxylic Acids; Clofibric Acid; Diclofenac; Drug Interactions; Esters; Hydrolases; Hydrolysis; Ibuprofen; In Vitro Techniques; Liver; Male; Naproxen; Physostigmine; Proadifen; Probenecid; Prodrugs; Rats; Rats, Sprague-Dawley; Refractometry; Solubility; Structure-Activity Relationship; Time Factors; Valproic Acid

1999