naproxen has been researched along with pilocarpine in 7 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (pilocarpine) | Trials (pilocarpine) | Recent Studies (post-2010) (pilocarpine) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 7,334 | 340 | 1,528 |
| Protein | Taxonomy | naproxen (IC50) | pilocarpine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.0267 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 3.84 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Fryer, AD; Okanlami, OA | 1 |
1 review(s) available for naproxen and pilocarpine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
6 other study(ies) available for naproxen and pilocarpine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Neuronal M2 muscarinic receptor function in guinea-pig lungs is inhibited by indomethacin.
Topics: Acetylcholine; Animals; Bronchoconstriction; Depression, Chemical; Drug Interactions; Electric Stimulation; Gallamine Triethiodide; Guinea Pigs; Indomethacin; Lung; Naproxen; Neurons; Parasympathetic Nervous System; Pilocarpine; Receptors, Muscarinic; Stereoisomerism; Vagus Nerve | 1993 |