Page last updated: 2024-09-04

naproxen and phenothiazine

naproxen has been researched along with phenothiazine in 3 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(phenothiazine)
Trials
(phenothiazine)
Recent Studies (post-2010) (phenothiazine)
4,5511,0571,4292,5537191

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)phenothiazine (IC50)
NADPH oxidase 1Homo sapiens (human)0.3589
rac GTPase-activating protein 1 isoform aHomo sapiens (human)18.5
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)2.236
Cytochrome P450 1A2Homo sapiens (human)0.016
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.461
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)1.4
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)4.643
Amine oxidase [flavin-containing] AHomo sapiens (human)0.592
Prostaglandin G/H synthase 1Homo sapiens (human)0.196
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.461
5-hydroxytryptamine receptor 2CHomo sapiens (human)2.236
Prostaglandin G/H synthase 2Homo sapiens (human)0.532
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.94
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.94

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carty, TJ; Moore, PF; Mylari, BL; Zembrowski, WJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1

Other Studies

3 other study(ies) available for naproxen and phenothiazine

ArticleYear
1,2-Dihydro-1-oxopyrrolo[3,2,1-kl]phenothiazine-2-carboxamides and congeners, dual cyclooxygenase/5-lipoxygenase inhibitors with antiinflammatory activity.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Line; Cyclooxygenase Inhibitors; Edema; Indicators and Reagents; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Models, Molecular; Molecular Structure; Prostaglandin Antagonists; Pyrroles; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazines

1990
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010