naproxen has been researched along with phenacetin in 21 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (phenacetin) | Trials (phenacetin) | Recent Studies (post-2010) (phenacetin) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 2,373 | 75 | 162 |
| Protein | Taxonomy | naproxen (IC50) | phenacetin (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.0287 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 13 (61.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Cihlar, T; Ho, ES; Mulato, AS | 1 |
| Brozic, P; Gobec, S; Rizner, TL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Anderluh, M; Brunskole, M; Gobec, S; Lanisnik Rizner, T; Stefane, B; Stojan, J; Zorko, K | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Balko, KM; Colby, DA; Mo, H | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Buttram, VC; Gravlee, LC; Hale, RW; Lifshitz, S | 1 |
| Castañeda-Hernández, G; García-López, P; Guízar-Sahagún, G; Martínez-Cruz, A | 1 |
| Acero, JL; Benitez, FJ; Real, FJ; Roldan, G | 1 |
| Acero, JL; Benitez, FJ; Casas, F; Real, FJ; Roldan, G | 1 |
| Birungi, G; Gumbi, BP; Moodley, B; Ndungu, PG | 1 |
1 trial(s) available for naproxen and phenacetin
| Article | Year |
|---|---|
Naproxen sodium vs. a combination of aspirin, phenacetin, caffeine and codeine phosphate for pain after major gynecologic surgery. A multicenter comparison.
Topics: Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Female; Genital Diseases, Female; Humans; Hysterectomy; Infertility, Female; Naproxen; Pain, Postoperative; Phenacetin | 1984 |
20 other study(ies) available for naproxen and phenacetin
| Article | Year |
|---|---|
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Molecular Structure; Tumor Cells, Cultured | 2005 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening.
Topics: Amino Acid Sequence; Ascomycota; Benzopyrans; Enzyme Inhibitors; Fungal Proteins; Melanins; Models, Molecular; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Structural Homology, Protein; Substrate Specificity | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A practical deuterium-free NMR method for the rapid determination of 1-octanol/water partition coefficients of pharmaceutical agents.
Topics: 1-Octanol; Magnetic Resonance Spectroscopy; Pharmaceutical Preparations; Water | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Acute spinal cord injury changes the disposition of some, but not all drugs given intravenously.
Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Female; Gentamicins; Metabolic Clearance Rate; Naproxen; Phenacetin; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Thoracic Vertebrae | 2007 |
Kinetics of aqueous chlorination of some pharmaceuticals and their elimination from water matrices.
Topics: Amoxicillin; Fresh Water; Halogenation; Hydrogen-Ion Concentration; Kinetics; Metoprolol; Naproxen; Pharmaceutical Preparations; Phenacetin; Water Pollutants, Chemical; Water Purification | 2010 |
Bromination of selected pharmaceuticals in water matrices.
Topics: Amoxicillin; Halogenation; Hydrochlorothiazide; Hydrogen-Ion Concentration; Kinetics; Metoprolol; Naproxen; Pharmaceutical Preparations; Phenacetin; Water Pollutants, Chemical | 2011 |
Detection and quantification of acidic drug residues in South African surface water using gas chromatography-mass spectrometry.
Topics: Acids, Carbocyclic; Aspirin; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Nalidixic Acid; Naproxen; Phenacetin; Rivers; South Africa; Water; Water Pollutants, Chemical | 2017 |