Page last updated: 2024-09-04

naproxen and parecoxib

naproxen has been researched along with parecoxib in 4 studies

Compound Research Comparison

Studies (naproxen)	Trials (naproxen)	Recent Studies (post-2010) (naproxen)	Studies (parecoxib)	Trials (parecoxib)	Recent Studies (post-2010) (parecoxib)
4,551	1,057	1,429	436	186	229

Protein Interaction Comparison

Protein	Taxonomy	naproxen (IC50)	parecoxib (IC50)
Prostaglandin G/H synthase 2	Homo sapiens (human)		0.005

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (75.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Goldstein, JL; Harris, SI; Hubbard, RC; Kuss, M	1
Burian, M; Geisslinger, G	1
Deray, G; Montalescot, G; Sibilia, J	1
Atkinson, TJ; Fudin, J; Jahn, HL; Kubotera, N; Rennick, AL; Rhorer, M	1

Reviews

3 review(s) available for naproxen and parecoxib

Article	Year
[Clinical pharmacology of the selective COX-2 inhibitors]. Der Orthopade, 2003, Volume: 32, Issue:12 Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Isoxazoles; Lactones; Naproxen; Osteoarthritis; Pain; Pain, Postoperative; Placebos; Pyrazoles; Sulfonamides; Sulfones	2003
[What do we know about the cardiovascular toxicity of the NSAIDs?]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:9 Spec No Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Case-Control Studies; Celecoxib; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Follow-Up Studies; Humans; Isoxazoles; Lactones; Meta-Analysis as Topic; Middle Aged; Naproxen; Pyrazoles; Randomized Controlled Trials as Topic; Risk Factors; Sulfonamides; Sulfones; Thrombosis; Time Factors	2006
What's new in NSAID pharmacotherapy: oral agents to injectables. Pain medicine (Malden, Mass.), 2013, Volume: 14 Suppl 1 Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Humans; Hyaluronic Acid; Hydrogen Sulfide; Ibuprofen; Injections; Injections, Intra-Articular; Isoxazoles; Nanoparticles; Naproxen; Nitric Oxide Donors; Vasodilator Agents	2013

Trials

1 trial(s) available for naproxen and parecoxib

Article	Year
Upper gastrointestinal safety evaluation of parecoxib sodium, a new parenteral cyclooxygenase-2-specific inhibitor, compared with ketorolac, naproxen, and placebo. Clinical therapeutics, 2001, Volume: 23, Issue:9 Topics: Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Gastric Mucosa; Humans; Infusions, Parenteral; Isoenzymes; Isoxazoles; Ketorolac; Male; Membrane Proteins; Naproxen; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases	2001

Article

Year

Upper gastrointestinal safety evaluation of parecoxib sodium, a new parenteral cyclooxygenase-2-specific inhibitor, compared with ketorolac, naproxen, and placebo.

Clinical therapeutics, 2001, Volume: 23, Issue:9

Topics: Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Gastric Mucosa; Humans; Infusions, Parenteral; Isoenzymes; Isoxazoles; Ketorolac; Male; Membrane Proteins; Naproxen; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases

2001