Page last updated: 2024-09-04

naproxen and p-aminohippuric acid

naproxen has been researched along with p-aminohippuric acid in 7 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(p-aminohippuric acid)
Trials
(p-aminohippuric acid)
Recent Studies (post-2010) (p-aminohippuric acid)
4,5511,0571,4292,2316488

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)p-aminohippuric acid (IC50)
Solute carrier family 22 member 6Homo sapiens (human)8.8

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Altman, RA; Borel, T; Davis, I; de Azambuja, F; Johnson, D; Liu, A; Sorrentino, JP; Udokwu, C; Yang, Y1
Bálint, G; Bartha, J; Bräunlich, H; Hably, C; Herceg, R1
Bartha, J; Bräunlich, H; Herceg, R1
Banki, K; Bartha, J; Bräunlich, H; Hably, C1

Reviews

1 review(s) available for naproxen and p-aminohippuric acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for naproxen and p-aminohippuric acid

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway.
    Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1

    Topics: Bacterial Proteins; Binding Sites; Biosynthetic Pathways; Carboxy-Lyases; Catalytic Domain; Crystallography, X-Ray; Diflunisal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kynurenine; Molecular Docking Simulation; NAD; Pseudomonas fluorescens; Structure-Activity Relationship; Tryptophan

2021
Comparison of the effects on inhibition of cyclooxygenase and thromboxane synthetase on renal excretion and haemodynamics in rats of different ages.
    Acta physiologica Hungarica, 1989, Volume: 73, Issue:1

    Topics: Age Factors; Animals; Cyclooxygenase Inhibitors; Diuresis; Female; Hemodynamics; Imidazoles; Indomethacin; Kidney; Male; Naproxen; p-Aminohippuric Acid; Rats; Renal Circulation; Thromboxane-A Synthase

1989
Influence of an inhibition of thromboxane synthetase by imidazole on kidney function in rats during postnatal development.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 275, Issue:1

    Topics: Aging; Animals; Female; Imidazoles; Kidney; Male; Naproxen; Oxidoreductases; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Thromboxane-A Synthase

1985
Effects of indomethacin and naproxen on renal p-amino-hippurate (PAH) excretion in rats during postnatal development.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 268, Issue:1

    Topics: Aging; Aminohippuric Acids; Animals; Diuresis; Female; Glomerular Filtration Rate; Hematocrit; Indomethacin; Male; Naproxen; p-Aminohippuric Acid; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Sodium

1984