naproxen has been researched along with oxaprozin in 15 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (oxaprozin) | Trials (oxaprozin) | Recent Studies (post-2010) (oxaprozin) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 180 | 26 | 51 |
| Protein | Taxonomy | naproxen (IC50) | oxaprozin (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.798 | |
| Serine hydroxymethyltransferase, mitochondrial | Homo sapiens (human) | 1.9498 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.11 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Famaey, JP; Ginsberg, F | 1 |
| Schorn, D | 1 |
| Carson, JL; Manoukian, AV | 1 |
| Al-Khenaizan, S; Sasseville, D; Schechter, JF | 1 |
| Chen, BY; Cheng, NN; Li, D; Shi, W; Wang, YM | 1 |
| Costa, D; Fernandes, E; Gomes, A; Lima, JL | 1 |
| Gümüş, C; Ince, F; Inci, MF; Kara, IM; Polat, S | 1 |
4 review(s) available for naproxen and oxaprozin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Nonsteroidal anti-inflammatory drug-induced hepatic disorders. Incidence and prevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cohort Studies; Diclofenac; Humans; Incidence; Indomethacin; Liver; Liver Diseases; Naproxen; Oxaprozin; Phenylbutazone; Propionates; Risk Factors; Sulindac | 1996 |
Pseudoporphyria induced by propionic acid derivatives.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Drug Eruptions; Female; Humans; Low Back Pain; Male; Naproxen; Oxaprozin; Photosensitivity Disorders; Porphyrias; Propionates; Skin Diseases, Vesiculobullous | 1999 |
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans; Ibuprofen; Meloxicam; Nabumetone; Naproxen; Osteoarthritis; Oxaprozin; Propionates; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiazoles | 2003 |
3 trial(s) available for naproxen and oxaprozin
| Article | Year |
|---|---|
A double-blind, parallel trial of oxaprozin versus naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Oxaprozin; Propionates | 1984 |
A comparison between oxaprozin and naproxen in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Naproxen; Oxaprozin; Oxazoles; Propionates | 1981 |
Analgesic and anti-inflammatory effects of oxaprozin and naproxen sodium after removal of impacted lower third molars: a randomized, double-blind, placebo-controlled crossover study.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Edema; Face; Female; Humans; Male; Mandible; Molar, Third; Naproxen; Oxaprozin; Pain, Postoperative; Placebos; Propionates; Prospective Studies; Range of Motion, Articular; Tooth, Impacted; Trismus; Young Adult | 2010 |
8 other study(ies) available for naproxen and oxaprozin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Singlet oxygen scavenging activity of non-steroidal anti-inflammatory drugs.
Topics: Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dose-Response Relationship, Drug; Etodolac; Free Radical Scavengers; Indoprofen; Ketorolac; Molecular Structure; Naproxen; Oxaprozin; Propionates; Singlet Oxygen; Tolmetin | 2008 |