Page last updated: 2024-09-04

naproxen and norethindrone

naproxen has been researched along with norethindrone in 9 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(norethindrone)
Trials
(norethindrone)
Recent Studies (post-2010) (norethindrone)
4,5511,0571,4294,295884303

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)norethindrone (IC50)
Estrogen receptorHomo sapiens (human)0.808
Glucocorticoid receptorHomo sapiens (human)0.433
Progesterone receptorHomo sapiens (human)0.0032
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.433
Androgen receptorRattus norvegicus (Norway rat)0.0711
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.433
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.433
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.433
Sodium-dependent serotonin transporterHomo sapiens (human)4.537

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Sapire, KE1
Faassen, F; Vromans, H1

Reviews

2 review(s) available for naproxen and norethindrone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Biowaivers for oral immediate-release products: implications of linear pharmacokinetics.
    Clinical pharmacokinetics, 2004, Volume: 43, Issue:15

    Topics: Administration, Oral; Animals; Bile; Biological Availability; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Estrenes; Furans; Humans; Ketoprofen; Naproxen; Norethindrone; Solubility; Therapeutic Equivalency

2004

Trials

1 trial(s) available for naproxen and norethindrone

ArticleYear
A study of bleeding patterns with two injectable contraceptives given postpartum and the effect of two non-hormonal treatments.
    Advances in contraception : the official journal of the Society for the Advancement of Contraception, 1991, Volume: 7, Issue:4

    Topics: Contraceptive Agents, Female; Double-Blind Method; Female; Humans; Injections; Medroxyprogesterone; Medroxyprogesterone Acetate; Naproxen; Norethindrone; Postpartum Period; Pregnancy; Tranexamic Acid; Uterine Hemorrhage

1991

Other Studies

6 other study(ies) available for naproxen and norethindrone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012