Page last updated: 2024-09-04

naproxen and niflumic acid

naproxen has been researched along with niflumic acid in 7 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(niflumic acid)
Trials
(niflumic acid)
Recent Studies (post-2010) (niflumic acid)
4,5511,0571,42972031160

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)niflumic acid (IC50)
Prostaglandin G/H synthase 1Homo sapiens (human)1.064
Prostaglandin G/H synthase 2Homo sapiens (human)0.918
Transcriptional enhancer factor TEF-3Homo sapiens (human)5.9
G-protein coupled receptor 35Homo sapiens (human)1.28

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chang, TK; Ensom, MH; Kiang, TK1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Boyle, E; Freeman, PC; Goudie, AC; Mangan, FR; Thomson, M1
Rivkin, I1
Bracht, A; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Lopez, CH; Sampaio, E; Yamamoto, NS1
Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC1

Reviews

2 review(s) available for naproxen and niflumic acid

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
    Paediatric drugs, 2022, Volume: 24, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain

2022

Other Studies

5 other study(ies) available for naproxen and niflumic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:12

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chelating Agents; Copper; Edema; Female; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Naproxen; Niflumic Acid; Peptic Ulcer; Prostaglandins E; Pyrroles; Rats

1976
The effect of bovine serum albumin on the in vitro inhibition of chemotaxis by anti-inflammatory agents.
    Agents and actions, 1977, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cattle; Chemotaxis, Leukocyte; Drug Interactions; Female; In Vitro Techniques; Naproxen; Neutrophils; Niflumic Acid; Phenylbutazone; Rabbits; Serum Albumin, Bovine; Time Factors

1977
The action of flufenamic acid and other nonsteroidal anti-inflammatories on sulfate transport in the isolated perfused rat liver.
    General pharmacology, 1999, Volume: 32, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Dose-Response Relationship, Drug; Flufenamic Acid; In Vitro Techniques; Liver; Male; Mefenamic Acid; Naproxen; Niflumic Acid; Perfusion; Piroxicam; Rats; Rats, Wistar; Sulfates; Sulfonamides; Sulfur Radioisotopes; Time Factors

1999