naproxen has been researched along with nabumetone in 62 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (nabumetone) | Trials (nabumetone) | Recent Studies (post-2010) (nabumetone) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 393 | 105 | 60 |
| Protein | Taxonomy | naproxen (IC50) | nabumetone (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 5 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 1.868 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 0.998 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.868 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (25.81) | 18.7374 |
| 1990's | 23 (37.10) | 18.2507 |
| 2000's | 15 (24.19) | 29.6817 |
| 2010's | 7 (11.29) | 24.3611 |
| 2020's | 1 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Freeman, PC; Gaster, LM; Goudie, AC; Hughes, BO; Lake, AW; Miller, D; Rose, CJ | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Anderluh, M; Brunskole, M; Gobec, S; Lanisnik Rizner, T; Stefane, B; Stojan, J; Zorko, K | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Ardizzone, S; Bianchi Porro, G; Caruso, I; Montone, F; Petrillo, M | 1 |
| Fleischmann, RM | 1 |
| Clarke, A; Cree, F; Emery, P; Kill, D; Poland, M; Redhead, R; Williams, P | 1 |
| Roth, SH | 3 |
| Dandona, P; Jeremy, JY | 1 |
| Barradas, MA; Dandona, P; Jeremy, JY; Kirk, RM; Mikhailidis, DP | 2 |
| Azzolini, V; Caruso, I; Cazzola, M; Montrone, F; Vaiani, G | 1 |
| Dandona, P; Jeremy, JY; Mikhailidis, DP; Thompson, CS | 1 |
| Kaidbey, KH; Mitchell, FN | 1 |
| Goodman, LA; Pisko, EJ; Rice, D; Strader, K; White, R | 1 |
| Jenner, PN | 1 |
| Cerlek, S; Dominis, M; Greb, WH; Hauptmann, E; von Schrader, HW; Zenić, N | 1 |
| Brobyn, RD | 1 |
| Bockow, BI; Box, P; Brodsky, AL; Espinoza, LR; Fleischmann, RM; Fogari, RA; Germain, BF; Lipani, JA; Mullen, BJ; Vasey, FB | 1 |
| Hazleman, BL; Thomas, PP | 1 |
| Poiley, JE | 1 |
| Bockow, BI; Box, P; Brodsky, AL; Burch, FX; Collins, RL; Fleischmann, RM; Keller, MI; Lipani, JA; Pisko, EJ; Poiley, JE | 1 |
| Boyle, EA; Freeman, PC; Mangan, FR; Thomson, MJ | 1 |
| Burry, HC; Mowles, E; Richards, AM; Treadwell, BL; Tweed, JM | 1 |
| Croydon, EA; Fostiropoulos, G | 1 |
| Famaey, JP; Ginsberg, F | 1 |
| Cytryn, E; Pintens, H; Verbruggen, LA | 1 |
| Bijlsma, JW; Lems, WF; van Berge Henegouwen, GP | 1 |
| Bjarnason, I; Hayllar, J | 1 |
| Bianchi Porro, G; Caruso, I; Imbesi, V; Montrone, F; Petrillo, M | 1 |
| Bennett, R; Caldron, P; Koepp, R; Mitchell, C; Roth, SH; Swenson, C | 1 |
| DeLapp, RE; Eversmeyer, W; Jensen, CP; Poland, M | 1 |
| DeLapp, RE; Morgan, GJ; Poland, M | 1 |
| DeLapp, RE; Lister, BJ; Poland, M | 1 |
| Carryl, OR; Spangler, RS | 1 |
| Constantine, G; Schnitzer, TJ | 1 |
| Martínez, LJ; Scaiano, JC | 1 |
| Knijff-Dutmer, EA; Martens, A; vd Laar, MA | 1 |
| Farr, PM; Meggitt, SJ | 1 |
| Checketts, SR; Morgan, GJ | 1 |
| Berry, M; Broadwell, LK; DeLapp, R; Krug, H; Mahowald, M; Palmer, RH | 1 |
| Goto, T; Matsumoto, H; Mikami, E; Nishida, M; Ohno, T | 1 |
| Chan, FK; Chan, LY; Ching, JY; Chung, SC; Hui, Y; Lai, AC; Lee, YT; Leung, WK; Sung, JJ; Wu, JC | 1 |
| de Nucci, G; Ferraz, JG; Giuliano, F; Pereira, R; Warner, TD | 1 |
| Browning, RA; Burgess, FW | 1 |
| Cha, HS; Jeon, CH; Kim, JS; Koh, EM; Koh, JH; Lee, CK | 1 |
| Ausiello, JC; Stafford, RS | 1 |
| Chen, BY; Cheng, NN; Li, D; Shi, W; Wang, YM | 1 |
| Ashworth, NL; Muhajarine, N; Peloso, PM; Stang, M | 2 |
| Chang, CE; Chen, W; Gilson, MK | 1 |
| Bjarnason, I; Bjornsson, E; Maiden, L; Premchand, P; Sherwood, R; Smale, S; Takeuchi, K; Thjodleifsson, B | 1 |
| Gonzalo-Garijo, MA; Pérez-Calderón, R; Pérez-Rangel, I; Sánchez-Vega, S; Zambonino, MA | 1 |
| Carrasco Garcia, I; Gomez-Traseira, C; Gonzalez Mendiola, R; Herranz Mañas, M; Laguna Martinez, JJ; Perez-Ezquerra, PR; Rubio Matos, A; Sanchez-Morillas, L | 1 |
| Changchien, E; Chiang, CH; Chin, HY; Lin, MF; Wang, CJ | 1 |
| Abbasi, B; Asadi, M; Dadfarnia, S; Haji Shabani, AM | 1 |
6 review(s) available for naproxen and nabumetone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Gastroscopic evaluation of the effects of nabumetone on the gastrointestinal mucosa of rheumatic patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Controlled Clinical Trials as Topic; Digestive System; Gastroscopy; Humans; Indomethacin; Nabumetone; Naproxen; Prospective Studies; Randomized Controlled Trials as Topic; Rheumatic Diseases | 1991 |
Upper gastrointestinal safety with nabumetone.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Chromium Radioisotopes; Clinical Trials as Topic; Digestive System; Double-Blind Method; Endoscopy; Gastrointestinal Hemorrhage; Humans; Longitudinal Studies; Nabumetone; Naproxen | 1992 |
NSAID gastropathy. The central issue.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Humans; Nabumetone; Naproxen; Peptic Ulcer | 1990 |
['Stomach-friendly' NSAIDs: careful optimism?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Butanones; Gastritis; Humans; Ibuprofen; Misoprostol; Nabumetone; Naproxen; Randomized Controlled Trials as Topic; Risk Factors; Stomach Ulcer | 1995 |
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans; Ibuprofen; Meloxicam; Nabumetone; Naproxen; Osteoarthritis; Oxaprozin; Propionates; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiazoles | 2003 |
28 trial(s) available for naproxen and nabumetone
| Article | Year |
|---|---|
Clinical efficacy and safety of nabumetone in rheumatoid arthritis and osteoarthritis.
Topics: Adult; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Butanones; Double-Blind Method; Female; Humans; Longitudinal Studies; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis | 1992 |
Nabumetone compared with naproxen in the treatment of rheumatoid arthritis: a multicenter, double blind, randomized, parallel group trial in hospital outpatients.
Topics: Adult; Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Double-Blind Method; Female; Hemoglobins; Humans; Male; Middle Aged; Nabumetone; Naproxen; Pain; Severity of Illness Index; Treatment Outcome | 1992 |
Analgesic activity of nabumetone versus naproxen in acute exacerbation of osteoarthritis. A short term study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Drug Evaluation; Female; Humans; Male; Nabumetone; Naproxen; Osteoarthritis | 1990 |
Photosensitizing potential of certain nonsteroidal anti-inflammatory agents.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Humans; Hypersensitivity, Immediate; Male; Nabumetone; Naproxen; Photosensitivity Disorders; Piroxicam; Propionates; Ultraviolet Rays | 1989 |
A 6-month, double-blind study comparing nabumetone to naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Butanones; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Random Allocation | 1987 |
Nabumetone in the treatment of skin and soft tissue injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Clinical Trials as Topic; Double-Blind Method; Edema; Female; Humans; Ibuprofen; Joints; Male; Middle Aged; Nabumetone; Naproxen; Pain; Random Allocation; Skin; Sprains and Strains | 1987 |
Endoscopic studies of nabumetone in patients with rheumatoid arthritis. A comparative endoscopic and histologic evaluation.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Butanones; Clinical Trials as Topic; Drug Administration Schedule; Female; Gastric Mucosa; Gastroscopy; Humans; Indomethacin; Male; Middle Aged; Nabumetone; Naproxen; Random Allocation | 1987 |
Endoscopy-controlled study of the safety of nabumetone compared with naproxen in arthritis therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Double-Blind Method; Duodenoscopy; Endoscopy; Esophagoscopy; Female; Gastric Mucosa; Gastroscopy; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis | 1987 |
Nabumetone in the treatment of active adult rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Random Allocation | 1987 |
Controlled evaluation of nabumetone in the treatment of active adult rheumatoid arthritis. Nabumetone versus naproxen double-blind parallel study.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Prospective Studies; Random Allocation | 1987 |
Single-blind comparative study of nabumetone (Relafen) versus naproxen in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Random Allocation | 1987 |
Nabumetone versus naproxen in the treatment of osteoarthritis. A six-month trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Random Allocation | 1987 |
Six-month multi-center study comparing nabumetone with naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Random Allocation | 1987 |
Nabumetone, a new non-steroidal anti-inflammatory drug: a comparison with naproxen.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Double-Blind Method; Humans; Nabumetone; Naproxen; Pain; Random Allocation; Time Factors | 1983 |
A comparative study of the effectiveness and safety of two non-steroidal anti-inflammatory agents, nabumetone and naproxen in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Random Allocation | 1982 |
Double-blind crossover study of nabumetone versus naproxen in the treatment of osteoarthritis of the knee and hip.
Topics: Anti-Inflammatory Agents; Butanones; Double-Blind Method; Drug Tolerance; Hip Joint; Humans; Knee Joint; Locomotion; Nabumetone; Naproxen; Osteoarthritis | 1982 |
Double-blind crossover study of nabumetone versus naproxen in the treatment of osteoarthritis.
Topics: Aged; Anti-Inflammatory Agents; Butanones; Double-Blind Method; Drug Tolerance; Female; Hip Joint; Humans; Knee Joint; Locomotion; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Random Allocation; Spinal Osteophytosis | 1982 |
Gastroduodenal tolerability of nabumetone versus naproxen in the treatment of rheumatic patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Double-Blind Method; Duodenitis; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Gastritis; Humans; Intestinal Mucosa; Male; Middle Aged; Nabumetone; Naproxen; Peptic Ulcer | 1995 |
A longterm endoscopic evaluation of patients with arthritis treated with nabumetone vs naproxen.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Double-Blind Method; Female; Follow-Up Studies; Gastroscopy; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Peptic Ulcer; Prospective Studies; Time Factors | 1994 |
Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy and safety of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in the elderly.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Male; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Life Style; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Etodolac (Lodine) in the treatment of osteoarthritis: recent studies.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Double-Blind Method; Etodolac; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Pain Measurement; Placebos | 1997 |
Effects of nabumetone compared with naproxen on platelet aggregation in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Cross-Over Studies; Cyclooxygenase Inhibitors; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Platelet Aggregation; Platelet Aggregation Inhibitors; Statistics, Nonparametric | 1999 |
Tolerability and efficacy of nabumetone and naproxen in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen | 2000 |
Randomized trial of low-dose misoprostol and naproxen vs. nabumetone to prevent recurrent upper gastrointestinal haemorrhage in users of non-steroidal anti-inflammatory drugs.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Prospective Studies; Recurrence | 2001 |
Cyclooxygenase selectivity of non-steroid anti-inflammatory drugs in humans: ex vivo evaluation.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Etodolac; Humans; Isoenzymes; Male; Meloxicam; Membrane Proteins; Nabumetone; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Thiazines; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Comparison of the efficacy and safety of naproxen CR and nabumetone in the treatment of patients with osteoarthritis of the knee.
Topics: Activities of Daily Living; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Constipation; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Nausea; Osteoarthritis, Knee; Pain Measurement; Single-Blind Method; Treatment Outcome; Walking | 2001 |
28 other study(ies) available for naproxen and nabumetone
| Article | Year |
|---|---|
4-(6-Methoxy-2-naphthyl)butan-2-one and related analogues, a novel structural class of antiinflammatory compounds.
Topics: Animals; Anti-Inflammatory Agents; Female; Gossypium; Granuloma; Naphthalenes; Rats; Structure-Activity Relationship | 1978 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening.
Topics: Amino Acid Sequence; Ascomycota; Benzopyrans; Enzyme Inhibitors; Fungal Proteins; Melanins; Models, Molecular; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Structural Homology, Protein; Substrate Specificity | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Nonsteroidal anti-inflammatory drug therapy and gastric side effects. Does nabumetone provide a solution?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Gastric Mucosa; Humans; Indomethacin; Male; Nabumetone; Naproxen; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane A2 | 1990 |
Effects of the prodrug nabumetone, and its active metabolite, 6-MNA, on human and rat gastric mucosal prostanoids and platelet function.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Butanones; Dinoprostone; Epoprostenol; Gastric Mucosa; Humans; Indomethacin; Male; Nabumetone; Naphthaleneacetic Acids; Naproxen; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Rats; Rats, Inbred Strains | 1990 |
The effect of nabumetone and its principal active metabolite on in vitro human gastric mucosal prostanoid synthesis and platelet function.
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Butanones; Culture Techniques; Dinoprostone; Epoprostenol; Gastric Mucosa; Humans; Indomethacin; Nabumetone; Naphthaleneacetic Acids; Naproxen; Platelet Aggregation; Thromboxane A2; Thromboxane B2 | 1990 |
Effect of the antiinflammatory prodrug, nabumetone and its principal active metabolite on rat gastric mucosal, aortic and platelet eicosanoid synthesis, in vitro and ex vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Blood Platelets; Butanones; Eicosanoids; Gastric Mucosa; In Vitro Techniques; Indomethacin; Male; Nabumetone; Naphthaleneacetic Acids; Naproxen; Prodrugs; Rats; Rats, Inbred Strains | 1990 |
Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new anti-inflammatory agent.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Female; Granuloma; Indomethacin; Nabumetone; Naproxen; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer | 1982 |
NSAIDs, Cox-2 inhibitors, and the gut.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase Inhibitors; Diclofenac; Digestive System; Humans; Indans; Nabumetone; Naproxen; Oxidative Phosphorylation; Piroxicam; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases | 1995 |
Comparative effects of nabumetone, naproxen, piroxicam, and diclofenac on rat gastric irritancy following acute exposure to OTC non-steroidal anti-inflammatory agents and other gastric irritants.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Gastric Mucosa; Male; Nabumetone; Naproxen; Nonprescription Drugs; Piroxicam; Rats; Rats, Wistar | 1995 |
Characterization of the transient intermediates generated from the photoexcitation of nabumetone: a comparison with naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Nabumetone; Naproxen; Oxygen; Photosensitizing Agents; Singlet Oxygen; Spectrometry, Fluorescence | 1998 |
Pseudoporphyria and propionic acid non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Drug Eruptions; Humans; Nabumetone; Naproxen; Porphyrias | 1999 |
Two cases of nabumetone induced pseudoporphyria.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Porphyria Cutanea Tarda | 1999 |
Simultaneous analysis of naproxen, nabumetone and its major metabolite 6-methoxy-2-naphthylacetic acid in pharmaceuticals and human urine by high-performance liquid chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Nabumetone; Naphthaleneacetic Acids; Naproxen; Reference Standards; Spectrophotometry, Ultraviolet | 2000 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors | 2001 |
Trends in medication use for osteoarthritis treatment.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Drug Utilization; Female; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; United States | 2002 |
A population based historical cohort study of the mortality associated with nabumetone, Arthrotec, diclofenac, and naproxen.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cause of Death; Chronic Disease; Cohort Studies; Diclofenac; Drug Combinations; Female; Humans; Logistic Models; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Risk; Saskatchewan; Survival Rate | 2004 |
Calculation of cyclodextrin binding affinities: energy, entropy, and implications for drug design.
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Benzene; Binding Sites; Butanones; Computer Simulation; Cyclodextrins; Drug Delivery Systems; Drug Design; Energy Transfer; Entropy; Flurbiprofen; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Nabumetone; Naproxen; Resorcinols | 2004 |
Risk of hospitalization with peptic ulcer disease or gastrointestinal hemorrhage associated with nabumetone, Arthrotec, diclofenac, and naproxen in a population based cohort study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cohort Studies; Databases, Factual; Diclofenac; Drug Combinations; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Peptic Ulcer; Risk Factors; Saskatchewan | 2005 |
Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colitis, Ulcerative; Crohn Disease; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Indomethacin; Inflammatory Bowel Diseases; Male; Middle Aged; Nabumetone; Naproxen; Prevalence; Recurrence; Sulfonamides | 2006 |
Fixed drug eruption due to nabumetone in a patient with previous fixed drug eruptions due to naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Drug Eruptions; Female; Humans; Middle Aged; Nabumetone; Naproxen; Skin Tests | 2011 |
Hypersensitivity to nabumetone: cross reactivity with naproxen.
Topics: Adult; Angioedema; Butanones; Cross Reactions; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Humans; Middle Aged; Nabumetone; Naproxen; Urticaria | 2013 |
Concentration of non-steroidal anti-inflammatory drugs in the pelvic floor muscles: an experimental comparative rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Chronic Pain; Diclofenac; Female; Meloxicam; Muscles; Nabumetone; Naproxen; Pelvic Floor; Pelvic Pain; Piroxicam; Rats; Rats, Wistar; Thiazines; Thiazoles | 2014 |
Vortex-assisted surfactant-enhanced emulsification microextraction based on solidification of floating organic drop combined with high performance liquid chromatography for determination of naproxen and nabumetone.
Topics: Animals; Butanones; Calibration; Chromatography, High Pressure Liquid; Emulsifying Agents; Limit of Detection; Liquid Phase Microextraction; Milk; Nabumetone; Naproxen; Surface-Active Agents; Wastewater; Water | 2015 |