naproxen has been researched along with n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide in 11 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide) | Trials (n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide) | Recent Studies (post-2010) (n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 1,220 | 3 | 229 |
| Protein | Taxonomy | naproxen (IC50) | n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide (IC50) |
|---|---|---|---|
| Prostaglandin E synthase | Homo sapiens (human) | 10 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 2.1 | |
| Aromatase | Homo sapiens (human) | 0.68 | |
| Prostaglandin G/H synthase 1 | Mus musculus (house mouse) | 1.67 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 3 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.9037 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 2.4333 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.1522 | |
| Carboxypeptidase B2 | Homo sapiens (human) | 1.8 | |
| Prostaglandin E synthase | Mus musculus (house mouse) | 0.007 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bohlin, L; Danielson, H; Noreen, Y; Perera, P; Ringbom, T | 1 |
| Bohlin, L; Noreen, Y; Perera, P; Ringbom, T; Segura, L | 1 |
| Ertan, M; Kazkayasi, I; Okay, G; Ozadali-Sari, K; Sarigol, D; Somuncuoglu, EI; Tel, BC; Tozkoparan, B; Unsal-Tan, O; Uzgoren-Baran, A | 1 |
| Barrios-Rodiles, M; Belley, A; Chadee, K; Keller, K | 1 |
| Wallace, JL | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, E; Konturek, PC; Konturek, SJ; KwiecieĊ, S; Pajdo, R; Pawlik, M; Ptak, A; Sliwowski, Z | 1 |
| Di Battista, JA; Fahmi, H; He, Y; Martel-Pelletier, J; Pelletier, JP; Zhang, M | 1 |
| Lozano, JJ; Pouplana, R; Ruiz, J | 1 |
| Andrews, J; Andrews, P; Djakiew, D; Krygier, S | 1 |
| Allen, RE; Mendias, CL; Tatsumi, R | 1 |
| Burstein, R; Jakubowski, M; Levy, D; Zhang, XC | 1 |
1 review(s) available for naproxen and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
| Article | Year |
|---|---|
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Humans; Ibuprofen; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles | 1999 |
10 other study(ies) available for naproxen and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
| Article | Year |
|---|---|
Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis.
Topics: Animals; Biological Assay; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Placenta; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep | 1998 |
Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis.
Topics: Animals; Cattle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; In Vitro Techniques; Isoenzymes; Plantago; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep; Triterpenes; Ursolic Acid | 1998 |
Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Drug Design; Edema; Humans; Inflammation; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Naproxen; Nociception; Pain; Pain Measurement; Structure-Activity Relationship; Thiazoles; Thiones; Triazoles | 2015 |
Nonsteroidal antiinflammatory drugs inhibit cyclooxygenase-2 enzyme activity but not mRNA expression in human macrophages.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression; Humans; Indomethacin; Isoenzymes; Lipopolysaccharides; Macrophages; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides | 1996 |
Gastroprotective and ulcer healing effects of nitric oxide-releasing non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Ethanol; Gastric Mucosa; Isoenzymes; Male; Membrane Proteins; Microcirculation; Models, Animal; Naproxen; Nitric Oxide; Nitrobenzenes; Nitroso Compounds; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Stomach; Stomach Ulcer; Sulfonamides | 2000 |
Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Naproxen; Nitrobenzenes; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Synovial Membrane | 2001 |
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.
Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Humans; Ibuprofen; In Situ Nick-End Labeling; Male; Mice; Naproxen; Nitrobenzenes; Prostatic Neoplasms; Sulfonamides; Tumor Cells, Cultured | 2002 |
Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Division; Cell Fusion; Cells, Cultured; Culture Media; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Immunohistochemistry; Isoenzymes; Luminescent Measurements; Male; Membrane Proteins; Myogenin; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Satellite Cells, Skeletal Muscle; Sulfonamides | 2004 |
Sensitization of meningeal nociceptors: inhibition by naproxen.
Topics: Administration, Topical; Animals; Cyclooxygenase Inhibitors; Electrophysiology; Infusions, Intravenous; Male; Meninges; Naproxen; Nitrobenzenes; Nociceptors; Rats; Rats, Sprague-Dawley; Sulfonamides | 2008 |