naproxen has been researched along with mocetinostat in 19 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (mocetinostat) | Trials (mocetinostat) | Recent Studies (post-2010) (mocetinostat) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 21,735 | 390 | 8,606 |
| Protein | Taxonomy | naproxen (IC50) | mocetinostat (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.7851 | |
| Nuclear receptor corepressor 1 | Homo sapiens (human) | 0.022 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.57 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.102 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.102 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.5717 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.3433 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.6725 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.3537 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.6386 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.6725 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.5717 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.6725 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 0.045 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Lubbe, S; Potgieter, A; Van Zyl, A; Van Zyl, J | 1 |
| Lubbe, S; Theron, CN; Van Zyl, A | 1 |
| Gale, D; Keenan, CM; Shoupe, TS; Wallace, JL | 1 |
| Blackburn, WD; Chatham, WW; Heck, LW; Loose, LD | 1 |
| Bell, CJ; McKnight, GW; Wallace, JL | 1 |
| Griswold, DE; Tzimas, MN | 1 |
| Bucolo, C; Spadaro, A | 1 |
| Asselin, I; Célestin, F; Entman, M; Goulet, M; Guérette, B; Huard, C; Roy, B; Roy, R; Skuk, D; Tardif, F; Tremblay, JP | 1 |
| Antonelli, E; Cirino, G; Coata, G; Distrutti, E; Federici, B; Fiorucci, S; Morelli, A; Morelli, O; Renzo, GD; Santucci, L; Soldato, PD | 1 |
| Kato, S; Kunikata, T; Miyazawa, T; Takeuchi, K; Tanaka, A | 1 |
| Dhir, A; Kulkarni, SK; Naidu, PS | 1 |
| Berti, F; Brini, AT; Clement, MG; De Gennaro Colonna, V; Manfredi, B; Polvani, G; Rossoni, G | 1 |
| Aras, H; Berberoğlu, A; Cağlayan, F; Güncü, GN; Kilinç, K | 1 |
| Bani, D; Bolla, M; Masini, E; Pini, A; Viappiani, S | 1 |
| Barbosa, AL; Bezerra, TS; Carvalho, NS; Chaves, LS; Damasceno, SR; Freitas, AL; Medeiros, JV; Oliveira, CB; Santana, AP; Silva, RO; Soares, PM; Souza, MH | 1 |
| Dong, L; Jurban, BJ; Sharma, NP; Smith, WL | 1 |
| Lanzi, C; Lucarini, L; Masini, E; Pini, A; Rosa, AC; Stark, H; Thurmond, RL; Veglia, E | 1 |
| Gouveia, FS; Lopes, LG; Lucetti, LT; Medeiros, JV; Ribeiro, RA; Santana, AP; Soares, PM; Sousa, EH; Souza, MH; Tavares, BM | 1 |
1 trial(s) available for naproxen and mocetinostat
| Article | Year |
|---|---|
Effect of systemically administered naproxen sodium on clinical parameters and myeloperoxidase and elastase-like activity levels in gingival crevicular fluid.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Debridement; Dental Scaling; Female; Gingival Crevicular Fluid; Humans; Male; Naproxen; Pancreatic Elastase; Periodontal Index; Periodontitis; Peroxidase | 2007 |
18 other study(ies) available for naproxen and mocetinostat
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
The influence of non-steroidal anti-inflammatory and antithyroid agents on myeloperoxidase-catalysed activities of human leucocytes.
Topics: Antithyroid Agents; Diiodotyrosine; Flufenamic Acid; Humans; Imidazoles; Indomethacin; Iodine Radioisotopes; Leukocytes; Models, Biological; Naproxen; Peroxidase; Peroxidases; Phagocytosis; Serum Albumin, Bovine; Sonication; Thyroid Gland; Thyroxine | 1979 |
Inhibitory effects of non-steroidal anti-inflammatory drugs on human myeloperoxidase.
Topics: Flufenamic Acid; Guaiacol; Humans; Indomethacin; Iodine; Leukocytes; Naproxen; Peroxidase; Peroxidases; Serum Albumin, Bovine | 1979 |
Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Dinoprostone; Drug Combinations; Indomethacin; Leukotriene B4; Male; Misoprostol; Naproxen; Peroxidase; Quinolines; Rats; Rats, Inbred Strains | 1992 |
Tenidap, in contrast to several available nonsteroidal antiinflammatory drugs, potently inhibits the release of activated neutrophil collagenase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Hypochlorous Acid; Ibuprofen; In Vitro Techniques; Indoles; Indomethacin; Microbial Collagenase; Naproxen; Neutrophils; Oxindoles; Peroxidase; Piroxicam; Reference Values; Superoxides | 1991 |
Adaptation of rat gastric mucosa to aspirin requires mucosal contact.
Topics: Adaptation, Physiological; Animals; Aspirin; Dinoprostone; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Indomethacin; Male; Naproxen; Ornithine Decarboxylase; Peroxidase; Rats; Rats, Wistar | 1995 |
Ultraviolet B-induced inflammatory cytokine production, in vivo: initial pharmacological characterization.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dose-Response Relationship, Radiation; Inflammation; Mice; Mice, Inbred BALB C; Naproxen; Peroxidase; Pyrrolidinones; Rolipram; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 1995 |
Effect of sodium naproxen on inflammatory response induced by anterior chamber paracentesis in the rabbit.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Atropine; Ciliary Body; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Female; Leukotriene B4; Mydriatics; Naproxen; Neutrophils; Ophthalmic Solutions; Peroxidase; Phenylephrine; Rabbits | 1995 |
Prevention by anti-LFA-1 of acute myoblast death following transplantation.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Apoptosis; beta-Galactosidase; Biomarkers; Cell Adhesion; Cell Death; Cell Line, Transformed; Fluoresceins; Genes, Reporter; Graft Rejection; Immunosuppressive Agents; Inflammation; Interleukin-1; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; Methylprednisolone; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, SCID; Muscle, Skeletal; Muscular Dystrophy, Animal; Naproxen; Necrosis; Neutrophils; Oxidative Stress; Peroxidase; Piroxicam; Radiation Chimera; Stem Cell Transplantation; Tacrolimus; Whole-Body Irradiation; Zymosan | 1997 |
Nitric oxide-releasing NSAIDs inhibit interleukin-1beta converting enzyme-like cysteine proteases and protect endothelial cells from apoptosis induced by TNFalpha.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase Inhibitors; Cell Line; Cysteine Proteinase Inhibitors; DNA Fragmentation; Endothelium, Vascular; Flurbiprofen; Gastric Mucosa; Humans; In Situ Nick-End Labeling; Male; Mice; Naproxen; Nitric Oxide; Peroxidase; Rats; Rats, Wistar | 1999 |
Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Naproxen; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley | 2002 |
Effect of naproxen, a non-selective cyclo-oxygenase inhibitor, on pentylenetetrazol-induced kindling in mice.
Topics: Animals; Behavior, Animal; Brain; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Glutathione; Hot Temperature; Hyperalgesia; Immersion; Injections, Intraperitoneal; Kindling, Neurologic; Male; Malondialdehyde; Mice; Motor Activity; Naproxen; Nitrites; Oxidative Stress; Pain Measurement; Pentylenetetrazole; Peroxidase | 2005 |
Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats.
Topics: Animals; Arginine; Arrhythmias, Cardiac; Cardiotonic Agents; Creatine Kinase; Epoprostenol; Isosorbide Dinitrate; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Naproxen; Nitric Oxide; Peroxidase; Polydeoxyribonucleotides; Random Allocation; Rats; Rats, Wistar; Thromboxane B2 | 2006 |
Prevention of bleomycin-induced lung fibrosis in mice by a novel approach of parallel inhibition of cyclooxygenase and nitric-oxide donation using NCX 466, a prototype cyclooxygenase inhibitor and nitric-oxide donor.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bleomycin; Collagen; Cyclooxygenase Inhibitors; Deoxyguanosine; Dinoprostone; Inflammation; Lung; Male; Mice; Mice, Inbred C57BL; Naproxen; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Peroxidase; Propionates; Prostaglandin-Endoperoxide Synthases; Pulmonary Fibrosis; Thiobarbiturates; Transforming Growth Factor beta | 2012 |
A sulfated-polysaccharide fraction from seaweed Gracilaria birdiae prevents naproxen-induced gastrointestinal damage in rats.
Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Glutathione; Gracilaria; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Naproxen; Peroxidase; Polysaccharides; Rats; Rats, Wistar | 2012 |
Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.
Topics: Acetylation; Amino Acid Sequence; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flurbiprofen; Guanidine; Heme; Humans; Indomethacin; Kinetics; Models, Biological; Mutant Proteins; Mutation; Naproxen; Oxygen; Palmitic Acid; Peroxidase; Protein Multimerization; Pyrazoles; Substrate Specificity; Sulfonamides | 2013 |
Prevention of bleomycin-induced lung inflammation and fibrosis in mice by naproxen and JNJ7777120 treatment.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Cyclooxygenase 2; Deoxyguanosine; Disease Models, Animal; Goblet Cells; Indoles; Lung; Mice; Muscle, Smooth; Naproxen; Oxidative Stress; Peroxidase; Piperazines; Pneumonia; Pulmonary Fibrosis; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta | 2014 |
The nitric oxide donor cis-[Ru(bpy)2(SO3)NO](PF6) increases gastric mucosa protection in mice--involvement of the soluble guanylate cyclase/K(ATP) pathway.
Topics: 2,2'-Dipyridyl; Animals; Cytokines; Ethanol; Gastric Mucosa; Guanylate Cyclase; Inflammation; KATP Channels; Mice; Naproxen; Nitrates; Nitric Oxide Donors; Nitrites; Organometallic Compounds; Peroxidase; Protective Agents; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2015 |