Page last updated: 2024-09-04

naproxen and mobic

naproxen has been researched along with mobic in 43 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(mobic)
Trials
(mobic)
Recent Studies (post-2010) (mobic)
4,5511,0571,4291,739396936

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)mobic (IC50)
Prostaglandin G/H synthase 1Homo sapiens (human)1.5593
Prostaglandin G/H synthase 2Homo sapiens (human)0.4364
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.1514

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (6.98)18.2507
2000's24 (55.81)29.6817
2010's14 (32.56)24.3611
2020's2 (4.65)2.80

Authors

AuthorsStudies
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Barceló, P; Bevis, PJ; Bluhmki, E; Distel, M; Le Loët, X; Schattenkirchner, M; Wojtulewski, JA1
Fox, SM; Johnston, SA1
Wallace, JL1
Jick, SS1
Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K1
Sadowski, T; Steinmeyer, J2
de Nucci, G; Ferraz, JG; Giuliano, F; Pereira, R; Warner, TD1
Bai, JC; Mauriño, E; Meddings, J; Niveloni, S; Pedreira, S; Smecuol, E; Sugai, E; Vazquez, H1
Kalsbeek-Batenburg, EM; Knijff-Dutmer, EA; Koerts, J; van de Laar, MA1
Jain, NK; Kulkarni, SK; Singh, A1
Chen, BY; Cheng, NN; Li, D; Shi, W; Wang, YM1
Lanes, S; Singh, G; Triadafilopoulos, G1
Dahlborg, R; Day, CA; Jacob, RF; Mason, RP; Walter, MF; Weng, Y1
Cefle, K; Erkal, H; Koçak, H; Köseoglu, BG; Oztürk, S; Palanduz, S1
Alessio, M; Artamonova, V; Baildam, E; Bandeira, M; Buoncompagni, A; Emminger, W; Falcini, F; Foeldvari, I; Gerloni, V; Hanft, G; Joos, R; Kone-Paut, I; Lenhardt, A; Martini, A; Mouy, R; Nikishina, I; Pachanov, ED; Prieur, AM; Ruperto, N; Schwarz, R; Shachbazian, Y; Sigmund, R; Simianer, S; Zulian, F1
Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD1
Adelsberg, JV; Bolognese, JA; Cavanaugh, P; Chen, PY; Giannini, EH; Goodman, S; Kiss, MH; Lovell, DJ; Reicin, AS; Reiff, A; Zavaler, MF1
Cağici, CA; Calişkan, EE; Erkan, AN; Gencay, S; Ozlüoğlu, LN; Sener, M; Yavuz, H; Yilmaz, I; Yilmazer, C1
Beer, M; Collmann, H; Girschick, HJ; Haubitz, I; Hiort, O; Schneider, P; Seyberth, HW; Shin, YS1
Hashkes, PJ; Laxer, RM1
Hilário, MO; Len, CA; Terreri, MT1
Chu, SC; Hsieh, YS; Li, TJ; Lu, KH; Lue, KH; Yang, SF1
Bazso, A; Consolaro, A; Filocamo, G; Magni-Manzoni, S; Malattia, C; Martini, A; Pistorio, A; Ravelli, A; Ruperto, N; Viola, S1
Alsancak, G; Demiralay, EC; Ozkan, SA1
Kumar, A; Kumar, P; Kumari, B1
Kasemier, J; Meek, IL; Movig, KL; van de Laar, MA; Vonkeman, HE1
Beshay, JE; Levy, M; Madden, CJ; Rickert, KL; Sarode, R; Scott, WW1
Changchien, E; Chiang, CH; Chin, HY; Lin, MF; Wang, CJ1
Atli, O; Burukoglu, D; Ilgin, S; Perk, BO; Uzun, B1
Matteson, EL; Thongprayoon, C; Ungprasert, P1
Choi, HK; Dalal, DS; Dubreuil, M; Felson, DT; Lee, T; Lu, N; Zhang, Y1
Anderson, B; Cooper, TE; Eccleston, C; Fisher, E; Wilkinson, NM1
Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC1

Reviews

9 review(s) available for naproxen and mobic

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Use of carprofen for the treatment of pain and inflammation in dogs.
    Journal of the American Veterinary Medical Association, 1997, May-15, Volume: 210, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles

1997
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
    The American journal of medicine, 1999, Dec-13, Volume: 107, Issue:6A

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Humans; Ibuprofen; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles

1999
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2003, Volume: 24, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans; Ibuprofen; Meloxicam; Nabumetone; Naproxen; Osteoarthritis; Oxaprozin; Propionates; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiazoles

2003
Update on the medical treatment of juvenile idiopathic arthritis.
    Current rheumatology reports, 2006, Volume: 8, Issue:6

    Topics: Antibodies, Blocking; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Humans; Immunologic Factors; Infliximab; Isoxazoles; Leflunomide; Meloxicam; Methotrexate; Naproxen; Rheumatology; Thiazines; Thiazoles

2006
Nonsteroidal anti-inflammatory drugs: cyclooxygenase 2 inhibitors.
    Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl

    Topics: Adolescent; Aspirin; Celecoxib; Child; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Interactions; Etoricoxib; Fever; Humans; Hypersensitivity, Immediate; Inflammation; Leukotrienes; Meloxicam; Naproxen; Pain; Prostaglandins; Pyrazoles; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome

2006
Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
    Stroke, 2016, Volume: 47, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cerebral Hemorrhage; Diclofenac; Humans; Ibuprofen; Incidence; Indomethacin; Lactones; Meloxicam; Naproxen; Observational Studies as Topic; Odds Ratio; Piroxicam; Proportional Hazards Models; Stroke; Sulfones; Thiazines; Thiazoles

2016
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-02, Volume: 8

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Celecoxib; Child; Child, Preschool; Chronic Disease; Chronic Pain; Fenoprofen; Humans; Ibuprofen; Lactones; Meloxicam; Methoxsalen; Naproxen; Randomized Controlled Trials as Topic; Sulfones; Thiazines; Thiazoles

2017
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
    Paediatric drugs, 2022, Volume: 24, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain

2022

Trials

10 trial(s) available for naproxen and mobic

ArticleYear
A six-month double-blind trial to compare the efficacy and safety of meloxicam 7.5 mg daily and naproxen 750 mg daily in patients with rheumatoid arthritis.
    British journal of rheumatology, 1996, Volume: 35 Suppl 1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Double-Blind Method; Drug Tolerance; Gastrointestinal Diseases; Humans; Meloxicam; Middle Aged; Naproxen; Thiazines; Thiazoles; Time Factors; Treatment Outcome

1996
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:10

    Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2

2000
Cyclooxygenase selectivity of non-steroid anti-inflammatory drugs in humans: ex vivo evaluation.
    European journal of pharmacology, 2001, Aug-24, Volume: 426, Issue:1-2

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Etodolac; Humans; Isoenzymes; Male; Meloxicam; Membrane Proteins; Nabumetone; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Thiazines; Thiazoles; Time Factors; Tumor Cells, Cultured

2001
Platelet function is inhibited by non-selective non-steroidal anti-inflammatory drugs but not by cyclo-oxygenase-2-selective inhibitors in patients with rheumatoid arthritis.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bleeding Time; Blood Platelets; Cross-Over Studies; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Meloxicam; Middle Aged; Naproxen; Platelet Aggregation; Random Allocation; Thiazines; Thiazoles; Thromboxane B2

2002
Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicam.
    The American journal of medicine, 2004, Jul-15, Volume: 117, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Diclofenac; Dose-Response Relationship, Drug; Europe; Female; Gastrointestinal Diseases; Humans; Male; Meloxicam; Middle Aged; Naproxen; North America; Piroxicam; Risk Factors; Severity of Illness Index; Thiazines; Thiazoles; Thromboembolism; Time Factors; Treatment Failure; Upper Gastrointestinal Tract

2004
A randomized, double-blind clinical trial of two doses of meloxicam compared with naproxen in children with juvenile idiopathic arthritis: short- and long-term efficacy and safety results.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:2

    Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Male; Meloxicam; Naproxen; Thiazines; Thiazoles; Treatment Outcome

2005
Evaluation of the comparative efficacy and tolerability of rofecoxib and naproxen in children and adolescents with juvenile rheumatoid arthritis: a 12-week randomized controlled clinical trial with a 52-week open-label extension.
    The Journal of rheumatology, 2006, Volume: 33, Issue:5

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Lactones; Longitudinal Studies; Male; Meloxicam; Naproxen; Sulfones; Thiazines; Thiazoles; Treatment Outcome

2006
[Postoperative pain management in clinics of otolaryngology].
    Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2006, Volume: 16, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Dipyrone; Etodolac; Female; Humans; Lactones; Male; Meloxicam; Middle Aged; Naproxen; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Pain, Postoperative; Postoperative Period; Sulfones; Thiazines; Thiazoles; Treatment Outcome

2006
Interference of NSAIDs with the thrombocyte inhibitory effect of aspirin: a placebo-controlled, ex vivo, serial placebo-controlled serial crossover study.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Administration Schedule; Drug Interactions; Etoricoxib; Female; Humans; Ibuprofen; Male; Meloxicam; Middle Aged; Naproxen; Netherlands; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Pyridines; Risk Assessment; Sulfones; Thiazines; Thiazoles; Time Factors; Young Adult

2013
Assessment of common nonsteroidal anti-inflammatory medications by whole blood aggregometry: a clinical evaluation for the perioperative setting.
    World neurosurgery, 2014, Volume: 82, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Celecoxib; Cyclooxygenase Inhibitors; Female; Healthy Volunteers; Humans; Ibuprofen; Male; Meloxicam; Middle Aged; Naproxen; Perioperative Care; Platelet Aggregation; Pyrazoles; Sulfonamides; Thiazines; Thiazoles; Young Adult

2014

Other Studies

24 other study(ies) available for naproxen and mobic

ArticleYear
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
The risk of gastrointestinal bleed, myocardial infarction, and newly diagnosed hypertension in users of meloxicam, diclofenac, naproxen, and piroxicam.
    Pharmacotherapy, 2000, Volume: 20, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Databases, Factual; Diclofenac; Gastrointestinal Hemorrhage; Humans; Hypertension; Isoenzymes; Meloxicam; Membrane Proteins; Myocardial Infarction; Naproxen; Piroxicam; Prostaglandin-Endoperoxide Synthases; Risk Assessment; Thiazines; Thiazoles; United Kingdom

2000
Effects of non-steroidal antiinflammatory drugs and dexamethasone on the activity and expression of matrix metalloproteinase-1, matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by bovine articular chondrocytes.
    Osteoarthritis and cartilage, 2001, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Collagenases; Dexamethasone; Glucocorticoids; Indomethacin; Interleukin-1; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinases; Meloxicam; Metalloendopeptidases; Naproxen; Precipitin Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazines; Thiazoles; Tissue Inhibitor of Metalloproteinase-1

2001
Acute gastrointestinal permeability responses to different non-steroidal anti-inflammatory drugs.
    Gut, 2001, Volume: 49, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chromatography, High Pressure Liquid; Confidence Intervals; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Female; Gastric Mucosa; Humans; Indomethacin; Intestinal Mucosa; Lactulose; Male; Mannitol; Meloxicam; Middle Aged; Naproxen; Permeability; Pyrazoles; Statistics, Nonparametric; Sucrose; Sulfonamides; Thiazines; Thiazoles

2001
Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Chondrocytes; Diclofenac; Dose-Response Relationship, Drug; Gene Expression Regulation; Indomethacin; Interleukin-1; Meloxicam; Naproxen; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Propionates; RNA, Messenger; Thiazines; Thiazoles

2002
Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects.
    Life sciences, 2002, May-03, Volume: 70, Issue:24

    Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Synergism; Drug Therapy, Combination; Meloxicam; Mice; Naproxen; Pain; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Sulfonamides; Thiazines; Thiazoles; Yohimbine

2002
Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs.
    Atherosclerosis, 2004, Volume: 177, Issue:2

    Topics: Animals; Antioxidants; Celecoxib; Cholesterol, LDL; Chromans; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Isoprostanes; Isoxazoles; Lactones; Meloxicam; Naproxen; Oxidation-Reduction; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles

2004
In vitro effects of selective and non-selective nonsteroidal anti-inflammatory drugs on the frequency of sister chromatid exchanges.
    Drugs in R&D, 2004, Volume: 5, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Female; Humans; Lymphocytes; Male; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Prostaglandin-Endoperoxide Synthases; Sister Chromatid Exchange; Thiazines; Thiazoles

2004
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2

2006
Effective NSAID treatment indicates that hyperprostaglandinism is affecting the clinical severity of childhood hypophosphatasia.
    Orphanet journal of rare diseases, 2006, Jun-28, Volume: 1

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Calcium Pyrophosphate; Child; Child, Preschool; Dose-Response Relationship, Drug; Fibroblasts; Humans; Hypophosphatasia; In Vitro Techniques; Male; Meloxicam; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridoxal Phosphate; Thiazines; Thiazoles

2006
Naproxen, meloxicam and methylprednisolone inhibit urokinase plasminogen activator and inhibitor and gelatinases expression during the early stage of osteoarthritis.
    Clinica chimica acta; international journal of clinical chemistry, 2008, Volume: 387, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gelatinases; Humans; Meloxicam; Methylprednisolone; Naproxen; Osteoarthritis; Thiazines; Thiazoles; Urokinase-Type Plasminogen Activator

2008
Development and validation of a composite disease activity score for juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2009, May-15, Volume: 61, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Cross-Sectional Studies; Disability Evaluation; Humans; Joints; Meloxicam; Methotrexate; Naproxen; Outcome Assessment, Health Care; Prognosis; Severity of Illness Index; Thiazines; Thiazoles; Treatment Outcome

2009
Determination of pKa values of nonsteroidal antiinflammatory drug-oxicams by RP-HPLC and their analysis in pharmaceutical dosage forms.
    Journal of separation science, 2009, Volume: 32, Issue:17

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Meloxicam; Molecular Structure; Naproxen; Pharmaceutical Preparations; Piroxicam; Thiazines; Thiazoles

2009
Protective effects of selective and non-selective cyclooxygenase inhibitors in an animal model of chronic stress.
    Neuroscience bulletin, 2010, Volume: 26, Issue:1

    Topics: Animals; Anxiety; Catalase; Chronic Disease; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Glutathione; Isoxazoles; Lactones; Lipid Peroxidation; Male; Meloxicam; Memory; Mice; Motor Activity; Naproxen; Nitrites; Random Allocation; Stress, Psychological; Sulfonamides; Sulfones; Thiazines; Thiazoles

2010
Concentration of non-steroidal anti-inflammatory drugs in the pelvic floor muscles: an experimental comparative rat model.
    Yonsei medical journal, 2014, Volume: 55, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Chronic Pain; Diclofenac; Female; Meloxicam; Muscles; Nabumetone; Naproxen; Pelvic Floor; Pelvic Pain; Piroxicam; Rats; Rats, Wistar; Thiazines; Thiazoles

2014
Evaluation of the reproductive toxicity of naproxen sodium and meloxicam in male rats.
    Human & experimental toxicology, 2015, Volume: 34, Issue:4

    Topics: Alprostadil; Animals; Catalase; Cyclooxygenase Inhibitors; Dinoprostone; Follicle Stimulating Hormone; Glutathione; Glutathione Peroxidase; Luteinizing Hormone; Male; Meloxicam; Naproxen; Rats, Wistar; Sperm Count; Sperm Motility; Superoxide Dismutase; Testis; Testosterone; Thiazines; Thiazoles

2015
Use of non-steroidal anti-inflammatory drugs correlates with the risk of venous thromboembolism in knee osteoarthritis patients: a UK population-based case-control study.
    Rheumatology (Oxford, England), 2016, Volume: 55, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Logistic Models; Male; Meloxicam; Middle Aged; Naproxen; Odds Ratio; Osteoarthritis, Knee; Risk Factors; Sulfones; Thiazines; Thiazoles; Treatment Outcome; United Kingdom; Venous Thromboembolism

2016