Page last updated: 2024-09-04

naproxen and misoprostol

naproxen has been researched along with misoprostol in 21 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(misoprostol)
Trials
(misoprostol)
Recent Studies (post-2010) (misoprostol)
4,5511,0571,4294,6111,5221,686

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's10 (47.62)18.2507
2000's6 (28.57)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gale, D; Keenan, CM; Shoupe, TS; Wallace, JL1
Gerson, CD; Gupta, R; Kornbluth, A1
Huq, M1
Aadland, E; Cohen, H; Fausa, O; Quinlan, D; Vatn, M1
Bijlsma, JW; Lems, WF; van Berge Henegouwen, GP1
Geis, GS1
DiBattista, JA; Martel-Pelletier, J; Pelletier, JP; Ranger, P1
Bruyn, GA; Geis, GS; Melo Gomes, JA; Roth, SH; Woods, EM; Zeeh, J1
Bianchi Porro, G; Lazzaroni, M; Petrillo, M1
McKenna, F1
Fitzpatrick, LR; Le, T; Sakurai, K1
Chan, FK; Chan, LY; Ching, JY; Chung, SC; Hui, Y; Lai, AC; Lee, YT; Leung, WK; Sung, JJ; Wu, JC1
Delgado Fernández, M; Diez García, F; Zambrana García, JL1
Ashworth, NL; Muhajarine, N; Peloso, PM; Stang, M2
Allen, RH; Bartz, D; Grimes, DA; Hubacher, D; O'Brien, P1
Baldelli, F; Cipriani, S; D'Amore, C; Distrutti, E; Fiorucci, S; Francisci, D; Mencarelli, A; Renga, B; Santucci, L1
Allen, RH; Bartz, D; Bernholc, A; Hubacher, D; Lopez, LM; O'Brien, PA; Zeng, Y1
Elkhouly, NI; Maher, MA1

Reviews

3 review(s) available for naproxen and misoprostol

ArticleYear
['Stomach-friendly' NSAIDs: careful optimism?].
    Nederlands tijdschrift voor geneeskunde, 1995, Nov-04, Volume: 139, Issue:44

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Butanones; Gastritis; Humans; Ibuprofen; Misoprostol; Nabumetone; Naproxen; Randomized Controlled Trials as Topic; Risk Factors; Stomach Ulcer

1995
Interventions for pain with intrauterine device insertion.
    The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Misoprostol; Naproxen; Oxytocics; Pain; Randomized Controlled Trials as Topic

2009
Interventions for pain with intrauterine device insertion.
    The Cochrane database of systematic reviews, 2015, Jul-29, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; Misoprostol; Naproxen; Oxytocics; Pain; Prilocaine; Randomized Controlled Trials as Topic

2015

Trials

7 trial(s) available for naproxen and misoprostol

ArticleYear
Protection by misoprostol against naproxen-induced gastric mucosal damage.
    The American journal of medicine, 1987, Jul-27, Volume: 83, Issue:1A

    Topics: Adolescent; Adult; Alprostadil; Anti-Ulcer Agents; Female; Gastric Mucosa; Gastroscopy; Humans; Male; Middle Aged; Misoprostol; Naproxen

1987
Efficacy and upper GI safety of diclofenac/misoprostol, piroxicam and naproxen in patients with osteoarthritis.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Diclofenac; Double-Blind Method; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Male; Misoprostol; Naproxen; Osteoarthritis; Piroxicam; Safety

1993
Double-blind comparison of efficacy and gastroduodenal safety of diclofenac/misoprostol, piroxicam, and naproxen in the treatment of osteoarthritis.
    Annals of the rheumatic diseases, 1993, Volume: 52, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Diclofenac; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Misoprostol; Naproxen; Osteoarthritis; Peptic Ulcer; Piroxicam

1993
Double-blind, double-dummy endoscopic comparison of the mucosal protective effects of misoprostol versus ranitidine on naproxen-induced mucosal injury to the stomach and duodenum in rheumatic patients.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Double-Blind Method; Duodenal Ulcer; Duodenum; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Misoprostol; Naproxen; Osteoarthritis; Placebos; Ranitidine; Stomach Ulcer

1997
Diclofenac/misoprostol: the European clinical experience.
    The Journal of rheumatology. Supplement, 1998, Volume: 51

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Combinations; Duodenal Ulcer; Duodenoscopy; Gastroscopy; Humans; Misoprostol; Naproxen; Osteoarthritis; Piroxicam; Stomach Ulcer

1998
Randomized trial of low-dose misoprostol and naproxen vs. nabumetone to prevent recurrent upper gastrointestinal haemorrhage in users of non-steroidal anti-inflammatory drugs.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Prospective Studies; Recurrence

2001
Different analgesics prior to intrauterine device insertion: is there any evidence of efficacy?
    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 2017, Volume: 22, Issue:3

    Topics: Adult; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Intrauterine Devices; Lidocaine; Misoprostol; Naproxen; Oxytocics; Pain Management; Pain, Procedural; Pelvic Pain; Prosthesis Implantation; Treatment Outcome; Young Adult

2017

Other Studies

11 other study(ies) available for naproxen and misoprostol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis.
    Gastroenterology, 1992, Volume: 102, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Dinoprostone; Drug Combinations; Indomethacin; Leukotriene B4; Male; Misoprostol; Naproxen; Peroxidase; Quinolines; Rats; Rats, Inbred Strains

1992
Life-threatening diarrhea after short-term misoprostol use in a patient with Crohn ileocolitis.
    Annals of internal medicine, 1990, Sep-15, Volume: 113, Issue:6

    Topics: Alprostadil; Anti-Ulcer Agents; Crohn Disease; Diarrhea; Female; Humans; Middle Aged; Misoprostol; Naproxen; Peptic Ulcer

1990
Neurological adverse effects of naproxen and misoprostol combination.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 1990, Volume: 40, Issue:339

    Topics: Alprostadil; Anti-Ulcer Agents; Ataxia; Drug Therapy, Combination; Humans; Male; Middle Aged; Misoprostol; Naproxen; Stomach Ulcer

1990
The reduced expression of glucocorticoid receptors in synovial cells induced by nonsteroidal antiinflammatory drugs can be reversed by prostaglandin E1 analog.
    The Journal of rheumatology, 1994, Volume: 21, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indomethacin; Misoprostol; Naproxen; Propionates; Receptors, Glucocorticoid; Synovial Membrane

1994
Effect of naproxen on the hamster gastric antrum: ulceration, adaptation and efficacy of anti-ulcer drugs.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:11

    Topics: Adaptation, Physiological; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cell Division; Cricetinae; Famotidine; Gastric Acid; Male; Mesocricetus; Misoprostol; Naproxen; Pyloric Antrum; Stomach Ulcer; Time Factors

1999
Upper gastrointestinal toxicity of rofecoxib and naproxen.
    The New England journal of medicine, 2001, May-03, Volume: 344, Issue:18

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Ethics, Medical; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Lactones; Middle Aged; Misoprostol; Naproxen; Proton Pump Inhibitors; Risk Factors; Sulfones

2001
A population based historical cohort study of the mortality associated with nabumetone, Arthrotec, diclofenac, and naproxen.
    The Journal of rheumatology, 2004, Volume: 31, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cause of Death; Chronic Disease; Cohort Studies; Diclofenac; Drug Combinations; Female; Humans; Logistic Models; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Risk; Saskatchewan; Survival Rate

2004
Risk of hospitalization with peptic ulcer disease or gastrointestinal hemorrhage associated with nabumetone, Arthrotec, diclofenac, and naproxen in a population based cohort study.
    The Journal of rheumatology, 2005, Volume: 32, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cohort Studies; Databases, Factual; Diclofenac; Drug Combinations; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Peptic Ulcer; Risk Factors; Saskatchewan

2005
In vivo administration of ritonavir worsens intestinal damage caused by cyclooxygease inhibitors.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: Alprostadil; Animals; Apoptosis; Aspirin; Chemokine CCL2; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; HIV Protease Inhibitors; HT29 Cells; Humans; Integrin alpha1beta1; Intestinal Mucosa; Intestine, Small; Ketoprofen; Mice; Mice, Inbred C57BL; Misoprostol; Naproxen; Nitric Oxide Synthase Type II; Ritonavir; RNA, Messenger; Tumor Necrosis Factor-alpha

2014