naproxen has been researched along with methylprednisolone in 21 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (methylprednisolone) | Trials (methylprednisolone) | Recent Studies (post-2010) (methylprednisolone) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 20,247 | 2,602 | 5,317 |
| Protein | Taxonomy | naproxen (IC50) | methylprednisolone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Homo sapiens (human) | 0.011 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.011 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.011 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.011 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 11 (52.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Lane, NE; Schurman, DJ; Smith, RL; Williams, RJ | 1 |
| Bello López, JL; Fonseca, E; Manso, F | 1 |
| Kumar, KL; Lucas, LM; McAfee, JH; Romney, DM; Smith, DL | 1 |
| Chaudhuri, G; Hayden, B; Soderberg, R; Zarem, H | 1 |
| Asselin, I; Célestin, F; Entman, M; Goulet, M; Guérette, B; Huard, C; Roy, B; Roy, R; Skuk, D; Tardif, F; Tremblay, JP | 1 |
| Croft, P; Hay, EM; Hosie, G; Lewis, M; Paterson, SM | 1 |
| Chu, SC; Hsieh, YS; Li, TJ; Lu, KH; Lue, KH; Yang, SF | 1 |
| Ertugrul, BM; Gencer, P; Ozturk, B; Sakarya, S; Saylak Ersoy, OM | 1 |
| De Nisco, A; De Rosa, G; Piastra, M; Rigante, D; Valentini, P | 1 |
1 review(s) available for naproxen and methylprednisolone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for naproxen and methylprednisolone
| Article | Year |
|---|---|
Treatment of nonseptic olecranon bursitis. A controlled, blinded prospective trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Bursitis; Double-Blind Method; Drug Therapy, Combination; Elbow Joint; Humans; Injections; Male; Methylprednisolone; Methylprednisolone Acetate; Middle Aged; Naproxen; Prospective Studies; Randomized Controlled Trials as Topic; Ulna | 1989 |
Pragmatic randomised controlled trial of local corticosteroid injection and naproxen for treatment of lateral epicondylitis of elbow in primary care.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Female; Humans; Injections, Intramuscular; Injections, Subcutaneous; Male; Methylprednisolone; Middle Aged; Naproxen; Tennis Elbow; Treatment Outcome | 1999 |
18 other study(ies) available for naproxen and methylprednisolone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Inhibition of interleukin 1 induced chondrocyte protease activity by a corticosteroid and a nonsteroidal antiinflammatory drug.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Caseins; Collagen; Endopeptidases; Interleukin-1; Methylprednisolone; Naproxen; Prostaglandins E; Protease Inhibitors | 1992 |
Sweet's syndrome during the chronic phase of chronic myeloid leukaemia.
Topics: Drug Therapy, Combination; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Chronic-Phase; Leukocytosis; Male; Methylprednisolone; Middle Aged; Naproxen; Neutrophils; Skin Diseases; Syndrome | 1990 |
Salvage of ischemic rabbit ear by BW-755C and steroids, but not by indomethacin.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Ear; Indomethacin; Ischemia; Methylprednisolone; Naproxen; Necrosis; Pyrazoles; Rabbits | 1987 |
Prevention by anti-LFA-1 of acute myoblast death following transplantation.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Apoptosis; beta-Galactosidase; Biomarkers; Cell Adhesion; Cell Death; Cell Line, Transformed; Fluoresceins; Genes, Reporter; Graft Rejection; Immunosuppressive Agents; Inflammation; Interleukin-1; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; Methylprednisolone; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, SCID; Muscle, Skeletal; Muscular Dystrophy, Animal; Naproxen; Necrosis; Neutrophils; Oxidative Stress; Peroxidase; Piroxicam; Radiation Chimera; Stem Cell Transplantation; Tacrolimus; Whole-Body Irradiation; Zymosan | 1997 |
Naproxen, meloxicam and methylprednisolone inhibit urokinase plasminogen activator and inhibitor and gelatinases expression during the early stage of osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gelatinases; Humans; Meloxicam; Methylprednisolone; Naproxen; Osteoarthritis; Thiazines; Thiazoles; Urokinase-Type Plasminogen Activator | 2008 |
Adult-onset Still's disease in an 83-year-old.
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Diagnosis, Differential; Female; Follow-Up Studies; Glucocorticoids; Humans; Methylprednisolone; Naproxen; Still's Disease, Adult-Onset; Tomography, X-Ray Computed | 2012 |
Efficacy of high-dose methylprednisolone pulses in a child with noninfectious persistent pleuropericarditis revealing systemic juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Diagnosis, Differential; Humans; Male; Methylprednisolone; Naproxen; Pericarditis; Pulse Therapy, Drug; Thoracentesis; Treatment Outcome | 2016 |