Page last updated: 2024-09-04

naproxen and mesalamine

naproxen has been researched along with mesalamine in 8 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(mesalamine)
Trials
(mesalamine)
Recent Studies (post-2010) (mesalamine)
4,5511,0571,4293,9065401,579

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)mesalamine (IC50)
microphthalmia-associated transcription factor isoform 9Homo sapiens (human)1.3007
Prostaglandin G/H synthase 1Ovis aries (sheep)7.73
Prostaglandin G/H synthase 2Homo sapiens (human)7.53
Thiosulfate sulfurtransferaseHomo sapiens (human)0.28
60 kDa chaperonin Escherichia coli3.245
10 kDa chaperonin Escherichia coli3.245
Hydroxyacid oxidase 1Mus musculus (house mouse)7.8
large T antigenBetapolyomavirus macacae19.1

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Wallace, JL1
Horváth, Z; Kiss, G; Kovács, V; Rácz, I; Regőczi, H; Szalai, M1

Reviews

3 review(s) available for naproxen and mesalamine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Nitric oxide-releasing mesalamine: potential utility for treatment of inflammatory bowel disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35 Suppl 2

    Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Colitis; Cytokines; Disease Models, Animal; Humans; Leukocytes; Mesalamine; Naproxen; Nitric Oxide; Rats

2003

Trials

1 trial(s) available for naproxen and mesalamine

ArticleYear
Mucosal healing effect of mesalazine granules in naproxen-induced small bowel enteropathy.
    World journal of gastroenterology, 2013, Feb-14, Volume: 19, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Female; Humans; Hungary; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Mesalamine; Middle Aged; Naproxen; Pilot Projects; Severity of Illness Index; Time Factors; Treatment Outcome; Wound Healing

2013

Other Studies

4 other study(ies) available for naproxen and mesalamine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012