naproxen has been researched along with mecamylamine in 2 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (mecamylamine) | Trials (mecamylamine) | Recent Studies (post-2010) (mecamylamine) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 1,997 | 68 | 376 |
| Protein | Taxonomy | naproxen (IC50) | mecamylamine (IC50) |
|---|---|---|---|
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | 0.44 | |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | 2.0833 | |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | 1.6133 | |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | 1.8 | |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | 0.6 | |
| Neuronal acetylcholine receptor subunit alpha-2 | Homo sapiens (human) | 3.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for naproxen and mecamylamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 other study(ies) available for naproxen and mecamylamine
| Article | Year |
|---|---|
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |