Compounds > naproxen
Page last updated: 2024-09-04

naproxen and lithocholic acid

naproxen has been researched along with lithocholic acid in 5 studies

Compound Research Comparison

Studies
(naproxen)		Trials
(naproxen)		Recent Studies (post-2010)
(naproxen)		Studies
(lithocholic acid)		Trials
(lithocholic acid)		Recent Studies (post-2010) (lithocholic acid)
4,5511,0571,4291,11124280

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)lithocholic acid (IC50)
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1Homo sapiens (human)4.823
60 kDa heat shock protein, mitochondrialHomo sapiens (human)10
Tyrosine-protein phosphatase non-receptor type 2Homo sapiens (human)6.12
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)2.71
10 kDa heat shock protein, mitochondrialHomo sapiens (human)10
Bile acid receptorHomo sapiens (human)0.0183
large T antigenBetapolyomavirus macacae26.1

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Kazancioglu, MZ; Sacher, JR; Saha, J; Skoda, EM; Wipf, P1
Bertucci, C1

Reviews

1 review(s) available for naproxen and lithocholic acid

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

4 other study(ies) available for naproxen and lithocholic acid

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
An uncharged oxetanyl sulfoxide as a covalent modifier for improving aqueous solubility.
    ACS medicinal chemistry letters, 2014, Aug-14, Volume: 5, Issue:8

    Topics:

2014
Enantioselective inhibition of the binding of rac-profens to human serum albumin induced by lithocholate.
    Chirality, 2001, Volume: 13, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Chromatography; Circular Dichroism; Drug Interactions; Fenoprofen; Humans; Ketoprofen; Lithocholic Acid; Naproxen; Phenylpropionates; Serum Albumin; Stereoisomerism; Substrate Specificity; Suprofen

2001