Compounds > naproxen
Page last updated: 2024-09-04

naproxen and l 663536

naproxen has been researched along with l 663536 in 2 studies

Compound Research Comparison

Studies
(naproxen)		Trials
(naproxen)		Recent Studies (post-2010)
(naproxen)		Studies
(l 663536)		Trials
(l 663536)		Recent Studies (post-2010) (l 663536)
4,5511,0571,4294854138

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)l 663536 (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.023
Prostaglandin E synthaseHomo sapiens (human)2.2274
Prostaglandin G/H synthase 1Ovis aries (sheep)8
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)0.57
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.023
Arachidonate 5-lipoxygenase-activating proteinHomo sapiens (human)0.025
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.023
Prostaglandin G/H synthase 2Homo sapiens (human)2.4
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.023
Leukotriene C4 synthaseHomo sapiens (human)3
Macrophage-expressed gene 1 proteinHomo sapiens (human)2.2
GABA theta subunitRattus norvegicus (Norway rat)0.023
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.023
Prostaglandin E synthase 2Homo sapiens (human)1.6

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kreft, AF; Musser, JH1
Ambrosi, G; Bauer, J; Elkady, M; Laufer, SA; Luderer, S; Nieß, R; Schaible, AM; Werz, O1

Reviews

1 review(s) available for naproxen and l 663536

ArticleYear
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
    Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines

1992

Other Studies

1 other study(ies) available for naproxen and l 663536

ArticleYear
Modified acidic nonsteroidal anti-inflammatory drugs as dual inhibitors of mPGES-1 and 5-LOX.
    Journal of medicinal chemistry, 2012, Oct-25, Volume: 55, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cell Line; Humans; Indomethacin; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Microsomes; Prostaglandin-E Synthases; Pyrazoles; Structure-Activity Relationship; Sulfonamides

2012