naproxen has been researched along with glycine in 8 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (glycine) | Trials (glycine) | Recent Studies (post-2010) (glycine) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 35,163 | 756 | 8,415 |
| Protein | Taxonomy | naproxen (IC50) | glycine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 1.4852 | |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | 106 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | 128 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bjørnsdottir, I; Honorè Hansen, S; Olsen, J | 1 |
| Corrigan, OI; Lane, ME; Levis, K; McDonald, GS | 1 |
| Cho, YH; Choi, D; Hwang, GS; Jung, J; Kim, J; Lee, HS; Park, HJ; Park, M; Ryu, DH; Shim, SB | 1 |
| Agrawal, S; Mishra, A; Pathak, K | 1 |
8 other study(ies) available for naproxen and glycine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Identification of coenzyme A-related tolmetin metabolites in rats: relationship with reactive drug metabolites.
Topics: Acyl Coenzyme A; Administration, Oral; Animals; Clofibric Acid; Glutathione; Glycine; Male; Naproxen; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Taurine; Tolmetin; Tritium | 2003 |
Comparative assessment of two indices of drug induced permeability changes in the perfused rat intestine.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Glycine; Ibuprofen; In Vitro Techniques; Intestinal Mucosa; Intestines; Ketoprofen; Naproxen; Permeability; Phenylalanine; Polyethylene Glycols; Rats | 2006 |
¹H NMR-based metabolic profiling of naproxen-induced toxicity in rats.
Topics: Animals; Choline; Dose-Response Relationship, Drug; Energy Metabolism; Glycine; Hydroxybutyrates; Kynurenic Acid; Magnetic Resonance Spectroscopy; Male; Naproxen; Pantothenic Acid; Phosphocreatine; Rats; Rats, Sprague-Dawley; Stomach; Tryptophan | 2011 |
Naproxen glycine conjugate-synthesis, pharmaceutical preformulation and pharmacodynamic evaluation.
Topics: Animals; Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Colitis; Colon; Drug Delivery Systems; Glycine; Hydrogen-Ion Concentration; Naproxen; Permeability; Prodrugs; Rats; Solubility | 2012 |