naproxen has been researched along with fenofibrate in 19 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (fenofibrate) | Trials (fenofibrate) | Recent Studies (post-2010) (fenofibrate) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 3,058 | 529 | 1,354 |
| 4,551 | 1,057 | 1,429 | 42 | 0 | 23 |
| Protein | Taxonomy | naproxen (IC50) | fenofibrate (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 2.371 | |
| Adenosine receptor A3 | Homo sapiens (human) | 5.701 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.701 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.118 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 2.371 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.701 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 8.633 | |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | 1 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 5.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 14 (73.68) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Hornung, S; Krill, SL; Vippagunta, SR; Wang, Z | 1 |
| Bhakay, A; Bilgili, E; Davé, RN; Iqbal, Z; Jerez-Rozo, JI; Michniak-Kohn, B; Pandya, N; Romañach, RJ; Sievens-Figueroa, L | 1 |
| Backhuijs, F; Martens, JA; Van den Mooter, G; Vialpando, M | 1 |
| Bilgili, E; Davé, RN; Iqbal, Z; Pielecha-Safira, B; Ramachandran, R; Romañach, R; Ying, Y; Zhang, J | 1 |
| Afolabi, A; Bilgili, E; Davé, RN; Iqbal, Z; Krull, SM; Li, M; Susarla, R; Ying, Y | 1 |
| Bögershausen, A; Hagedorn, M; Hoffmann, S; Liebich, L; Massing, U; Mende, S; Rischer, M | 1 |
| Bergonzi, A; Clasen, C; Koekoekx, R; Michiels, E; Pas, T; Rousseau, F; Schymkowitz, J; Van den Mooter, G; Vergauwen, B | 1 |
| Brinkmann, J; Luebbert, C; Rest, F; Sadowski, G | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
1 review(s) available for naproxen and fenofibrate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
18 other study(ies) available for naproxen and fenofibrate
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Factors affecting the formation of eutectic solid dispersions and their dissolution behavior.
Topics: Drug Carriers; Fenofibrate; Flurbiprofen; Griseofulvin; Ibuprofen; Models, Chemical; Molecular Weight; Naproxen; Polyethylene Glycols; Sodium Dodecyl Sulfate; Solubility; Transition Temperature; Water | 2007 |
Preparation and characterization of hydroxypropyl methyl cellulose films containing stable BCS Class II drug nanoparticles for pharmaceutical applications.
Topics: Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Drug Carriers; Drug Compounding; Elastic Modulus; Feasibility Studies; Fenofibrate; Glycerol; Griseofulvin; Hydrogen Bonding; Hypromellose Derivatives; Kinetics; Methylcellulose; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Naproxen; Particle Size; Plasticizers; Solubility; Spectroscopy, Near-Infrared; Spectrum Analysis, Raman; Surface Properties; Surface-Active Agents; Technology, Pharmaceutical | 2012 |
Risk assessment of premature drug release during wet granulation of ordered mesoporous silica loaded with poorly soluble compounds itraconazole, fenofibrate, naproxen, and ibuprofen.
Topics: Calorimetry, Differential Scanning; Carboxymethylcellulose Sodium; Excipients; Fenofibrate; Ibuprofen; Itraconazole; Naproxen; Particle Size; Porosity; Powders; Risk Assessment; Silicon Dioxide; Solubility; Temperature | 2012 |
Raman spectroscopy for in-line and off-line quantification of poorly soluble drugs in strip films.
Topics: Calibration; Chemistry, Pharmaceutical; Fenofibrate; Nanoparticles; Naproxen; Principal Component Analysis; Spectrum Analysis, Raman | 2014 |
Polymer strip films as a robust, surfactant-free platform for delivery of BCS Class II drug nanoparticles.
Topics: Azo Compounds; Drug Delivery Systems; Fenofibrate; Glycerol; Griseofulvin; Hypromellose Derivatives; Nanoparticles; Naproxen; Phenylbutazone; Solubility | 2015 |
Rapid development of API nano-formulations from screening to production combining dual centrifugation and wet agitator bead milling.
Topics: Centrifugation; Excipients; Fenofibrate; Microscopy, Electron, Scanning; Nanoparticles; Naproxen; Polymers; Surface-Active Agents; Technology, Pharmaceutical | 2019 |
Preparation of Amorphous Solid Dispersions by Cryomilling: Chemical and Physical Concerns Related to Active Pharmaceutical Ingredients and Carriers.
Topics: Cinnarizine; Crystallization; Drug Carriers; Drug Compounding; Drug Stability; Dynamic Light Scattering; Fenofibrate; Gelatin; Glass; Hypromellose Derivatives; Indomethacin; Molecular Structure; Molecular Weight; Naproxen; Povidone; Serum Albumin, Bovine; Solubility; Spectroscopy, Fourier Transform Infrared; Transition Temperature; Viscosity | 2020 |
Solubility of Pharmaceutical Ingredients in Natural Edible Oils.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cinnarizine; Coconut Oil; Drug Compounding; Drug Delivery Systems; Excipients; Felodipine; Fenofibrate; Griseofulvin; Ibuprofen; Indomethacin; Models, Molecular; Naproxen; Plant Oils; Solubility; Soybean Oil; Spectrum Analysis, Raman; Thermodynamics; Transition Temperature; Triglycerides | 2020 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |